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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for AAGUGCU

Z-value: 1.15

Motif logo

miRNA associated with seed AAGUGCU

NamemiRBASE accession
MIMAT0000684
MIMAT0000715
MIMAT0000717
MIMAT0000718
MIMAT0005931
MIMAT0000724
MIMAT0000726
MIMAT0002834
MIMAT0002843
MIMAT0002846
MIMAT0002856
MIMAT0002825

Activity profile of AAGUGCU motif

Sorted Z-values of AAGUGCU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAGUGCU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.7 2.0 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.6 1.9 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.6 2.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.4 1.6 GO:0009956 radial pattern formation(GO:0009956)
0.4 1.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.4 2.5 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 0.9 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.3 1.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.3 0.8 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.3 1.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.2 0.5 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.2 0.7 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.2 0.7 GO:0061386 closure of optic fissure(GO:0061386)
0.2 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 5.7 GO:0002347 response to tumor cell(GO:0002347)
0.2 1.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.2 0.5 GO:0060988 lipid tube assembly(GO:0060988)
0.2 1.2 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.2 0.7 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.2 0.9 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 3.7 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 1.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.7 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 1.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.4 GO:0048627 myoblast development(GO:0048627)
0.1 0.4 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.4 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.4 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.4 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.7 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.7 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 2.0 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.5 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.3 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.1 3.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.9 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.1 0.2 GO:0070428 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.1 1.2 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.7 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.5 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.3 GO:0033341 regulation of collagen binding(GO:0033341)
0.1 0.3 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.9 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.0 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.4 GO:0032489 aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.2 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 1.0 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.1 0.3 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.3 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.9 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.1 1.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 1.3 GO:0007614 short-term memory(GO:0007614)
0.1 0.3 GO:0030047 actin modification(GO:0030047)
0.1 0.5 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.5 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.7 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.4 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029) common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.4 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.0 0.4 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 1.0 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 1.1 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.8 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 1.3 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.5 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.0 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.6 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.8 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.7 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.5 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.2 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.6 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.6 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.2 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 2.5 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.9 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0 0.4 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.5 3.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 1.0 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.3 2.8 GO:0005610 laminin-5 complex(GO:0005610)
0.2 3.9 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 0.8 GO:0031213 RSF complex(GO:0031213)
0.1 0.4 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 0.3 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.0 0.8 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.5 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 5.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.7 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.5 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.0 0.9 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.8 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.6 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 5.4 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.8 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 2.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.7 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.1 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 1.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332) micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.4 2.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.2 1.2 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 1.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 1.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 2.5 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 3.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.4 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.1 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.7 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.4 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0003696 satellite DNA binding(GO:0003696)
0.0 1.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.3 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.7 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.3 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.6 GO:0044548 S100 protein binding(GO:0044548) structural molecule activity conferring elasticity(GO:0097493)
0.0 1.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.6 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 1.0 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 1.2 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 1.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 2.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 2.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.7 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.9 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.2 PID FGF PATHWAY FGF signaling pathway
0.0 1.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 5.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.5 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 4.5 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.7 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation