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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for AAUACUG

Z-value: 1.93

Motif logo

miRNA associated with seed AAUACUG

NamemiRBASE accession
MIMAT0000318
MIMAT0000617
MIMAT0001536

Activity profile of AAUACUG motif

Sorted Z-values of AAUACUG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUACUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.7 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.6 1.8 GO:2000974 mitral valve formation(GO:0003192) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.5 1.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.4 1.2 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.4 1.2 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4 1.2 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.3 1.0 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.3 1.0 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.3 1.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.3 1.8 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.3 1.5 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 1.3 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.3 4.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 1.7 GO:0022614 membrane to membrane docking(GO:0022614)
0.2 0.7 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.2 1.2 GO:0021557 optic cup structural organization(GO:0003409) oculomotor nerve development(GO:0021557) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.2 0.9 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 0.7 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.2 0.7 GO:0008057 eye pigment granule organization(GO:0008057)
0.2 1.8 GO:0003383 apical constriction(GO:0003383)
0.2 1.3 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058) positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.2 0.7 GO:0070898 RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898)
0.2 0.8 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.2 1.3 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.2 1.0 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.2 1.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 1.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.2 0.6 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 0.6 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.2 1.7 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 0.6 GO:0001543 ovarian follicle rupture(GO:0001543)
0.2 0.9 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.2 0.7 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 0.5 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2 1.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 0.5 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.2 0.2 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.2 1.3 GO:0038107 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
0.2 0.6 GO:1903542 negative regulation of exosomal secretion(GO:1903542)
0.1 0.9 GO:0021764 amygdala development(GO:0021764)
0.1 0.4 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.9 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.7 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.6 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.1 1.4 GO:0051013 microtubule severing(GO:0051013)
0.1 2.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 1.8 GO:1901166 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 0.9 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.1 0.5 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.3 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.8 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.3 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1 0.3 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.5 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 0.3 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.1 0.5 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.1 0.7 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.5 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.4 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.8 GO:0030578 PML body organization(GO:0030578)
0.1 0.8 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.4 GO:1904978 regulation of endosome organization(GO:1904978)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 0.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.6 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 2.0 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.7 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 1.4 GO:0060613 fat pad development(GO:0060613)
0.1 1.0 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.3 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.7 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 2.3 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.5 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 1.0 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 1.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.2 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.1 0.2 GO:0043400 cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.1 0.6 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.3 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.1 0.3 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.5 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.4 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.2 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 1.0 GO:0006477 protein sulfation(GO:0006477)
0.1 1.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.6 GO:0050957 equilibrioception(GO:0050957)
0.1 1.0 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1 1.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.1 0.2 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.1 0.2 GO:0019085 early viral transcription(GO:0019085)
0.1 0.5 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.2 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 1.0 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.1 0.5 GO:0032808 lacrimal gland development(GO:0032808)
0.1 0.1 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 2.3 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 2.3 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.6 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.8 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.5 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.1 0.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.7 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.2 GO:0051413 response to cortisone(GO:0051413)
0.1 0.7 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.8 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 1.9 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 1.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.9 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.3 GO:0018032 protein amidation(GO:0018032)
0.0 0.3 GO:0032455 nerve growth factor processing(GO:0032455)
0.0 0.5 GO:0060174 limb bud formation(GO:0060174)
0.0 0.3 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 1.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.4 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.2 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.4 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.6 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 1.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 1.2 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.9 GO:0016180 snRNA processing(GO:0016180)
0.0 1.1 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.7 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0035973 aggrephagy(GO:0035973)
0.0 0.4 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.2 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.8 GO:0045116 protein neddylation(GO:0045116)
0.0 0.5 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.4 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 2.4 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 1.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.2 GO:1903624 regulation of apoptotic DNA fragmentation(GO:1902510) regulation of DNA catabolic process(GO:1903624)
0.0 2.9 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.7 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.7 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.4 GO:0015074 DNA integration(GO:0015074)
0.0 0.6 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 1.5 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.5 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.6 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.8 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 1.5 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.1 GO:1903515 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.8 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 0.2 GO:0003091 renal water homeostasis(GO:0003091)
0.0 0.6 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 0.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.2 GO:0072641 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.2 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 0.1 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.2 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.3 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.6 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.4 GO:0007379 segment specification(GO:0007379)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.0 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.5 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.4 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.8 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.0 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.8 GO:0001662 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.5 GO:0006363 transcription elongation from RNA polymerase I promoter(GO:0006362) termination of RNA polymerase I transcription(GO:0006363)
0.0 0.3 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.9 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.3 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.8 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996) positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.0 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.5 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.4 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 0.5 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.3 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.4 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
0.0 0.2 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.2 GO:0042953 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.5 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.4 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.2 GO:0014029 neural crest formation(GO:0014029)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.3 0.8 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) glial limiting end-foot(GO:0097451)
0.3 1.3 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.2 1.3 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.2 1.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 0.9 GO:0005606 laminin-1 complex(GO:0005606) laminin-11 complex(GO:0043260)
0.2 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.2 2.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 1.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 0.7 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.2 1.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.6 GO:0031592 centrosomal corona(GO:0031592)
0.1 4.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 2.2 GO:0061700 GATOR2 complex(GO:0061700)
0.1 1.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 2.0 GO:0016600 flotillin complex(GO:0016600)
0.1 0.3 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 0.7 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 1.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 1.0 GO:0051286 cell tip(GO:0051286)
0.1 1.7 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.7 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0070695 FHF complex(GO:0070695)
0.1 0.2 GO:0075341 host cell PML body(GO:0075341)
0.1 0.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 1.8 GO:0042588 zymogen granule(GO:0042588)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.7 GO:0001739 sex chromatin(GO:0001739)
0.1 1.0 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 0.9 GO:0032039 integrator complex(GO:0032039)
0.1 0.2 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.1 0.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.8 GO:0045180 basal cortex(GO:0045180)
0.1 0.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 2.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.5 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0072487 MSL complex(GO:0072487)
0.0 0.8 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0043293 apoptosome(GO:0043293)
0.0 0.7 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 1.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.0 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 1.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.7 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 1.2 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.5 GO:0043219 lateral loop(GO:0043219)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.3 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593) postsynaptic recycling endosome(GO:0098837)
0.0 2.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.5 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124) STAGA complex(GO:0030914)
0.0 1.5 GO:0097542 ciliary tip(GO:0097542)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 1.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.7 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.8 GO:0005811 lipid particle(GO:0005811)
0.0 1.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 1.2 GO:0002102 podosome(GO:0002102)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 3.1 GO:0098862 cluster of actin-based cell projections(GO:0098862)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 3.0 GO:0030027 lamellipodium(GO:0030027)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 9.6 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 0.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 1.0 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.3 1.3 GO:0047298 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.3 0.8 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.2 0.7 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.2 0.7 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.2 0.8 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 0.8 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.2 0.5 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.2 1.3 GO:0050815 phosphoserine binding(GO:0050815)
0.2 0.8 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 1.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.4 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 1.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 1.0 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 1.9 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.1 0.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.7 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 1.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.8 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.5 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.7 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1 0.4 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 0.6 GO:0052843 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.6 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.3 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.9 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 2.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.7 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.1 1.5 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.6 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.0 GO:0030911 TPR domain binding(GO:0030911)
0.1 2.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 1.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 1.8 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 1.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.1 1.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.9 GO:0005112 Notch binding(GO:0005112)
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.7 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 0.4 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.8 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.1 1.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.7 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.3 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 1.5 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 1.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 4.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 2.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 1.2 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.8 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 2.6 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 1.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.8 GO:0097602 cullin family protein binding(GO:0097602)
0.0 1.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.1 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0 1.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.3 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.0 1.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.5 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 2.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.2 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.9 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 2.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.5 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.7 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.5 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 4.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 3.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.7 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.5 PID IGF1 PATHWAY IGF1 pathway
0.0 4.6 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 3.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 4.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.5 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.6 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.4 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 6.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.6 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.1 2.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.9 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 3.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 1.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.1 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.5 REACTOME SIGNAL AMPLIFICATION Genes involved in Signal amplification
0.0 0.9 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.8 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 1.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 2.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.1 REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX Genes involved in Formation of RNA Pol II elongation complex
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 1.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.3 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases