avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Name	miRBASE accession
hsa-miR-365a-3p Links miRBase	MIMAT0000710
hsa-miR-365b-3p Links miRBase	MIMAT0022834

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.3	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.2	0.9	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.2	0.7	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2	1.5	GO:0072675	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2	0.9	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1	0.6	GO:0009956	radial pattern formation(GO:0009956)
0.1	0.5	GO:1903045	neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1	0.6	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
0.1	0.4	GO:0061349	chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.1	2.0	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	0.3	GO:0035978	mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1	0.2	GO:0006679	glucosylceramide biosynthetic process(GO:0006679)
0.1	1.6	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.1	0.3	GO:0043328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.1	0.2	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.0	0.2	GO:0010847	regulation of chromatin assembly(GO:0010847)
0.0	0.5	GO:0035766	cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0	0.5	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	0.9	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	1.6	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0	0.4	GO:0021759	globus pallidus development(GO:0021759)
0.0	0.1	GO:0035283	rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.2	GO:0072658	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0	0.2	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0	0.3	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.1	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0	0.2	GO:2000973	vitellogenesis(GO:0007296) regulation of pro-B cell differentiation(GO:2000973)
0.0	0.1	GO:0097535	lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0	0.2	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.2	GO:1903677	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0	0.5	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.2	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.2	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.1	GO:0021836	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0	0.4	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
0.0	0.2	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:1903215	negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0	0.1	GO:1902725	negative regulation of satellite cell differentiation(GO:1902725)
0.0	0.4	GO:0045116	protein neddylation(GO:0045116)
0.0	0.2	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.1	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0	0.0	GO:0060382	regulation of DNA strand elongation(GO:0060382)
0.0	0.5	GO:2001014	regulation of skeletal muscle cell differentiation(GO:2001014)
0.0	0.2	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.4	GO:2000696	regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0	0.0	GO:0060406	positive regulation of penile erection(GO:0060406)
0.0	0.2	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0	0.3	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.0	0.6	GO:2000178	negative regulation of neural precursor cell proliferation(GO:2000178)
0.0	0.2	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.3	GO:0072189	ureter development(GO:0072189)
0.0	0.4	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.1	GO:0090076	relaxation of skeletal muscle(GO:0090076)
0.0	0.2	GO:0090557	establishment of endothelial intestinal barrier(GO:0090557)
0.0	0.5	GO:0070306	lens fiber cell differentiation(GO:0070306)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0000814	ESCRT II complex(GO:0000814)
0.1	0.3	GO:0031213	RSF complex(GO:0031213)
0.1	0.6	GO:0070876	SOSS complex(GO:0070876)
0.0	1.6	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.3	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.9	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	0.9	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.3	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.3	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	1.5	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.3	GO:0001741	XY body(GO:0001741)
0.0	1.9	GO:0005604	basement membrane(GO:0005604)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.1	0.4	GO:0005115	receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1	1.6	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.9	GO:0045545	syndecan binding(GO:0045545)
0.1	1.5	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1	0.3	GO:0035501	MH1 domain binding(GO:0035501)
0.0	0.1	GO:0004421	hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0	0.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.5	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	1.6	GO:0042379	chemokine receptor binding(GO:0042379)
0.0	0.5	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.1	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0	0.4	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	3.4	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.2	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.4	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0	0.5	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.3	GO:0035198	miRNA binding(GO:0035198)
0.0	0.2	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.0	0.2	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.6	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.5	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.4	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.1	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.2	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.6	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.0	GO:0031685	adenosine receptor binding(GO:0031685)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.6	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.9	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.2	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.4	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	1.0	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	3.4	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.6	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.5	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.2	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.4	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.0	1.2	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.6	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity