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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ACAGUAC

Z-value: 1.50

Motif logo

miRNA associated with seed ACAGUAC

NamemiRBASE accession
MIMAT0000099

Activity profile of ACAGUAC motif

Sorted Z-values of ACAGUAC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ACAGUAC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.4 1.3 GO:0097195 pilomotor reflex(GO:0097195)
0.4 1.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.4 2.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.4 1.1 GO:0045210 FasL biosynthetic process(GO:0045210)
0.3 0.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.3 1.4 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.3 1.7 GO:0035063 nuclear speck organization(GO:0035063)
0.3 0.9 GO:0021722 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.3 1.9 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.3 1.5 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.3 1.0 GO:0007538 primary sex determination(GO:0007538)
0.2 1.4 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.2 2.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 0.8 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 2.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.2 1.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.7 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.8 GO:0090325 regulation of locomotion involved in locomotory behavior(GO:0090325)
0.2 0.8 GO:0008050 female courtship behavior(GO:0008050)
0.2 0.5 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.7 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.4 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 1.9 GO:0060174 limb bud formation(GO:0060174)
0.1 2.9 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.1 0.7 GO:1902724 positive regulation of skeletal muscle cell proliferation(GO:0014858) mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.7 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 1.0 GO:0015798 myo-inositol transport(GO:0015798)
0.1 0.4 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.5 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.8 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.6 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 1.9 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.4 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 1.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.3 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1 0.4 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.4 GO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905007)
0.1 1.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.7 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.6 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.4 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.5 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.5 GO:0006344 optic cup formation involved in camera-type eye development(GO:0003408) maintenance of chromatin silencing(GO:0006344)
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.4 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.8 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.5 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.5 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.2 GO:0019085 early viral transcription(GO:0019085)
0.1 0.5 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.7 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.4 GO:0048388 endosomal lumen acidification(GO:0048388)
0.1 0.3 GO:0035519 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.1 1.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.1 0.3 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.9 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.6 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.4 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 0.8 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.9 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.8 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.6 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.7 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.4 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 2.2 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.2 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.6 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.6 GO:0014029 neural crest formation(GO:0014029)
0.0 1.1 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.9 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.3 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.9 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.9 GO:0032060 bleb assembly(GO:0032060)
0.0 1.4 GO:0016577 histone demethylation(GO:0016577)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.6 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.9 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 1.7 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 1.3 GO:0007020 microtubule nucleation(GO:0007020)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0 0.1 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.7 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.7 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.2 GO:0008343 adult feeding behavior(GO:0008343)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0035412 regulation of catenin import into nucleus(GO:0035412) negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.7 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.7 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.3 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 1.0 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.6 GO:0045589 regulation of regulatory T cell differentiation(GO:0045589)
0.0 0.2 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.9 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.5 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.0 0.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.2 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.6 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 0.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.2 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.2 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 0.3 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.6 GO:0070534 protein K63-linked ubiquitination(GO:0070534)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005595 collagen type XII trimer(GO:0005595)
0.2 0.7 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.2 1.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.2 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 2.4 GO:0005577 fibrinogen complex(GO:0005577)
0.1 2.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.4 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 0.5 GO:0031213 RSF complex(GO:0031213)
0.1 1.9 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.4 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.6 GO:0097452 GAIT complex(GO:0097452)
0.1 0.9 GO:0030314 junctional membrane complex(GO:0030314)
0.1 2.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 2.0 GO:0071564 npBAF complex(GO:0071564)
0.1 0.7 GO:0042382 paraspeckles(GO:0042382)
0.1 0.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 0.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.0 1.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.6 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.6 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 4.3 GO:0016605 PML body(GO:0016605)
0.0 1.9 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 0.2 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.4 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 1.4 GO:0016235 aggresome(GO:0016235)
0.0 1.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.7 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0042588 zymogen granule(GO:0042588)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.7 GO:0031904 endosome lumen(GO:0031904)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 0.7 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.5 2.1 GO:0070052 collagen V binding(GO:0070052)
0.4 0.4 GO:0031690 adrenergic receptor binding(GO:0031690)
0.3 1.0 GO:0005365 myo-inositol transmembrane transporter activity(GO:0005365)
0.3 0.9 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.3 1.5 GO:0052841 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.2 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 1.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 0.5 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 1.0 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.9 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 2.9 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 1.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 2.8 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.4 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.1 1.0 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 2.1 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 2.1 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.1 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 2.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 0.7 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 5.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.5 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 0.4 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 1.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.2 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.5 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.8 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.8 GO:0034452 dynactin binding(GO:0034452)
0.0 1.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 1.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 1.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.8 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.4 GO:0005114 transforming growth factor beta receptor activity, type I(GO:0005025) type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.7 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 1.3 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 1.1 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.4 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.0 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 0.9 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 1.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 1.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 0.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.8 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 2.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.3 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 2.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.7 PID IFNG PATHWAY IFN-gamma pathway
0.0 2.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.2 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.9 PID FGF PATHWAY FGF signaling pathway
0.0 0.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.3 PID EPO PATHWAY EPO signaling pathway
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.2 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.9 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.6 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.8 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.9 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 2.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 2.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade