Project
avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for ACCCUGU
Z-value: 0.78
Motif logo
miRNA associated with seed ACCCUGU
| Name | miRBASE accession |
|---|---|
|
hsa-miR-10a-5p
|
MIMAT0000253 |
|
hsa-miR-10b-5p
|
MIMAT0000254 |
Activity profile of ACCCUGU motif
Sorted Z-values of ACCCUGU motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ACCCUGU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.2 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.2 | 1.5 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.2 | 0.5 | GO:0031587 | positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) |
| 0.1 | 0.7 | GO:0060399 | positive regulation of growth hormone receptor signaling pathway(GO:0060399) |
| 0.1 | 0.6 | GO:0003409 | optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623) |
| 0.1 | 0.3 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
| 0.1 | 0.9 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
| 0.1 | 0.6 | GO:1900147 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) |
| 0.1 | 0.5 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
| 0.1 | 0.5 | GO:0021773 | striatal medium spiny neuron differentiation(GO:0021773) positive regulation of long-term neuronal synaptic plasticity(GO:0048170) NMDA glutamate receptor clustering(GO:0097114) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969) |
| 0.1 | 0.3 | GO:0048627 | myoblast development(GO:0048627) |
| 0.1 | 0.6 | GO:1904550 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.1 | 0.2 | GO:1904562 | phosphatidylinositol 5-phosphate metabolic process(GO:1904562) |
| 0.1 | 1.7 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.1 | 0.2 | GO:0045763 | negative regulation of cellular amino acid metabolic process(GO:0045763) |
| 0.1 | 0.3 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
| 0.1 | 0.3 | GO:0060011 | Sertoli cell proliferation(GO:0060011) |
| 0.1 | 0.2 | GO:0007493 | endodermal cell fate determination(GO:0007493) |
| 0.0 | 0.2 | GO:1905123 | regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123) |
| 0.0 | 0.2 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.0 | 0.1 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930) |
| 0.0 | 0.3 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.0 | 0.4 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.0 | 0.2 | GO:0010847 | regulation of chromatin assembly(GO:0010847) |
| 0.0 | 0.2 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.0 | 0.4 | GO:1904628 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.0 | 1.1 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.0 | 0.6 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.0 | 0.5 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 0.2 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.0 | 0.3 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
| 0.0 | 0.3 | GO:0072502 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.0 | 0.4 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 0.0 | 0.1 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.0 | 0.1 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 0.0 | 0.1 | GO:0043634 | polyadenylation-dependent ncRNA catabolic process(GO:0043634) |
| 0.0 | 0.6 | GO:0006783 | heme biosynthetic process(GO:0006783) |
| 0.0 | 0.2 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.8 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.1 | 0.3 | GO:0002945 | cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945) |
| 0.1 | 0.6 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.0 | 0.9 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.0 | 0.5 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.1 | GO:0090498 | extrinsic component of Golgi membrane(GO:0090498) |
| 0.0 | 0.3 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 0.5 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.3 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 0.6 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.5 | GO:0010369 | chromocenter(GO:0010369) |
| 0.0 | 0.0 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.0 | 0.1 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.0 | 0.1 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.0 | 0.5 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.4 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.8 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.1 | 0.4 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.1 | 0.3 | GO:0047389 | glycerophosphocholine phosphodiesterase activity(GO:0047389) |
| 0.1 | 0.6 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.1 | 0.5 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.0 | 1.2 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.8 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.0 | 0.3 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.0 | 0.6 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.3 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.0 | 0.4 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.2 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.0 | 0.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.6 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 0.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.3 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.0 | 0.6 | GO:0032452 | histone demethylase activity(GO:0032452) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 0.6 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 0.6 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 1.5 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 0.7 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII | Genes involved in CREB phosphorylation through the activation of CaMKII |
| 0.0 | 0.6 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |