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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for AGCACCA

Z-value: 3.12

Motif logo

miRNA associated with seed AGCACCA

NamemiRBASE accession
MIMAT0000086
MIMAT0000100
MIMAT0000681

Activity profile of AGCACCA motif

Sorted Z-values of AGCACCA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCACCA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0034970 histone H3-R2 methylation(GO:0034970)
1.4 4.2 GO:0008057 eye pigment granule organization(GO:0008057)
1.2 3.7 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
1.2 3.6 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
1.2 3.5 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
1.0 9.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
1.0 3.0 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
1.0 3.0 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.9 2.7 GO:2000349 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.9 8.9 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.8 2.4 GO:0071109 superior temporal gyrus development(GO:0071109)
0.8 3.9 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.8 2.3 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.8 5.4 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.7 1.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.7 2.8 GO:1990927 vesicle-mediated cholesterol transport(GO:0090119) short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.7 3.3 GO:0051541 elastin metabolic process(GO:0051541)
0.6 1.8 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.6 3.6 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.6 2.4 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.5 2.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.5 2.1 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.5 1.5 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.5 4.0 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.5 1.4 GO:2000705 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.5 1.4 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.4 1.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.4 1.6 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.4 3.2 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.4 2.0 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.4 1.9 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.4 1.5 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.4 4.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.4 2.2 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.4 1.8 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.4 4.9 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.3 3.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.3 3.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.3 1.3 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.3 9.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.3 1.0 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.3 1.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.3 1.9 GO:0097327 response to antineoplastic agent(GO:0097327) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.3 1.3 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3 1.9 GO:0090135 positive regulation of synapse structural plasticity(GO:0051835) actin filament branching(GO:0090135)
0.3 2.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 1.8 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.3 0.9 GO:0035283 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.3 0.9 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.3 2.2 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.3 1.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 0.8 GO:0010360 negative regulation of anion channel activity(GO:0010360) Golgi to plasma membrane CFTR protein transport(GO:0043000)
0.3 9.5 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.3 1.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.2 1.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.7 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.2 3.0 GO:0006477 protein sulfation(GO:0006477)
0.2 2.5 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.2 2.9 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 0.9 GO:0072254 metanephric mesangial cell differentiation(GO:0072209) metanephric glomerular mesangial cell differentiation(GO:0072254) metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2 1.1 GO:0036343 negative regulation of extracellular matrix disassembly(GO:0010716) psychomotor behavior(GO:0036343)
0.2 1.3 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.2 2.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.6 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.2 0.8 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.2 1.4 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 1.8 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.2 1.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 1.8 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.2 0.8 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.2 1.9 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.2 3.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 0.5 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.2 0.5 GO:0060921 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.2 1.0 GO:0042633 molting cycle(GO:0042303) hair cycle(GO:0042633)
0.2 0.9 GO:0035617 stress granule disassembly(GO:0035617)
0.2 0.5 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.2 0.5 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.2 7.7 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.2 1.0 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.2 1.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 1.7 GO:1904179 positive regulation of adipose tissue development(GO:1904179)
0.2 1.5 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.2 0.5 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 3.7 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1 2.2 GO:0033227 dsRNA transport(GO:0033227)
0.1 1.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 5.2 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 1.7 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1 2.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 3.3 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 0.8 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 1.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.7 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 1.7 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 2.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.9 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 3.8 GO:0035855 megakaryocyte development(GO:0035855)
0.1 1.6 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.6 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 1.9 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.1 0.2 GO:0019882 antigen processing and presentation(GO:0019882)
0.1 1.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 1.7 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 1.8 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.3 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.1 2.4 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.1 1.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 0.8 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.1 1.0 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 0.5 GO:0033600 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 1.1 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.1 0.4 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 2.8 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.1 0.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.7 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 1.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
0.1 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.5 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 2.7 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 2.0 GO:0006853 carnitine shuttle(GO:0006853)
0.1 0.6 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.8 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.1 0.7 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.4 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.4 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.5 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 0.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.7 GO:0061097 regulation of protein tyrosine kinase activity(GO:0061097)
0.1 1.1 GO:0015074 DNA integration(GO:0015074)
0.1 1.9 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 1.2 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.1 0.9 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.2 GO:2000302 positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 0.7 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 0.9 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 1.7 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.6 GO:0035494 SNARE complex disassembly(GO:0035494)
0.1 0.6 GO:0003417 growth plate cartilage development(GO:0003417)
0.1 1.5 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.4 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.6 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 2.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 1.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.8 GO:0035973 aggrephagy(GO:0035973)
0.1 0.9 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 3.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 0.7 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 1.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.8 GO:0014029 neural crest formation(GO:0014029)
0.1 0.5 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 1.3 GO:0045116 protein neddylation(GO:0045116)
0.1 0.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 6.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.2 GO:0072189 ureter development(GO:0072189)
0.1 3.3 GO:1901998 toxin transport(GO:1901998)
0.1 1.6 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 1.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 1.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 0.3 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.5 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 1.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.8 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 1.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.4 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 7.7 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 1.2 GO:2000780 negative regulation of double-strand break repair(GO:2000780)
0.0 6.6 GO:0048593 camera-type eye morphogenesis(GO:0048593)
0.0 1.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.9 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 1.4 GO:0022038 corpus callosum development(GO:0022038)
0.0 1.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 2.7 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.7 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 2.5 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 3.2 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.8 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 1.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0070836 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 2.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.2 GO:0051549 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.7 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.5 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 1.8 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 1.1 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.2 GO:0060384 innervation(GO:0060384)
0.0 0.9 GO:0051438 regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0 1.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.4 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.3 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 1.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.5 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.1 GO:0035627 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.0 1.2 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 1.8 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.0 4.4 GO:1901800 positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.2 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 2.1 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 1.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.6 GO:0030855 epithelial cell differentiation(GO:0030855)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.7 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 2.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 3.7 GO:0070268 cornification(GO:0070268)
0.0 0.2 GO:0015808 L-alanine transport(GO:0015808)
0.0 2.0 GO:0008544 epidermis development(GO:0008544)
0.0 2.7 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 1.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.1 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 4.2 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.4 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 2.2 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.0 1.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.3 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.3 GO:0071397 cellular response to cholesterol(GO:0071397)
0.0 1.2 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 1.3 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.0 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.6 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 2.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.6 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 1.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:0071409 response to cycloheximide(GO:0046898) cellular response to cycloheximide(GO:0071409)
0.0 0.3 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.5 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 0.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.5 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.8 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 0.1 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.3 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 1.1 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 1.0 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.7 GO:0001881 receptor recycling(GO:0001881)
0.0 0.0 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 0.7 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071)
0.0 0.8 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:1990032 parallel fiber(GO:1990032)
1.1 9.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.8 2.4 GO:0005584 collagen type I trimer(GO:0005584)
0.7 2.0 GO:0000814 ESCRT II complex(GO:0000814)
0.5 2.2 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.4 2.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.4 5.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.3 1.7 GO:0043260 laminin-1 complex(GO:0005606) laminin-11 complex(GO:0043260)
0.3 0.9 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.3 5.3 GO:0031209 SCAR complex(GO:0031209)
0.3 1.3 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.3 3.0 GO:0032009 early phagosome(GO:0032009)
0.2 1.7 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 6.2 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 5.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 0.6 GO:0042565 RNA nuclear export complex(GO:0042565)
0.2 0.8 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.2 3.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 1.9 GO:0030175 filopodium(GO:0030175)
0.2 1.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 1.6 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 1.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2 4.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 1.9 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 7.3 GO:0030057 desmosome(GO:0030057)
0.2 1.2 GO:0097452 GAIT complex(GO:0097452)
0.1 3.2 GO:0032433 filopodium tip(GO:0032433)
0.1 2.4 GO:0036449 microtubule minus-end(GO:0036449)
0.1 2.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 1.9 GO:0000322 storage vacuole(GO:0000322)
0.1 3.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.1 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.3 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 0.8 GO:0070545 PeBoW complex(GO:0070545)
0.1 2.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.0 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 1.5 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.5 GO:0031905 early endosome lumen(GO:0031905)
0.1 3.0 GO:0043194 axon initial segment(GO:0043194)
0.1 1.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.0 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 6.7 GO:0002102 podosome(GO:0002102)
0.1 2.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 3.7 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 2.2 GO:0010369 chromocenter(GO:0010369)
0.1 0.3 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 2.1 GO:0042599 lamellar body(GO:0042599)
0.1 0.7 GO:0035976 AP1 complex(GO:0035976)
0.1 2.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.0 GO:0030897 HOPS complex(GO:0030897)
0.1 0.2 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 2.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 10.1 GO:0005776 autophagosome(GO:0005776)
0.1 1.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.7 GO:0071564 npBAF complex(GO:0071564)
0.1 0.8 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.8 GO:0042587 glycogen granule(GO:0042587)
0.1 0.9 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 2.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 6.9 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 1.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.6 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 4.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.9 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 1.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 4.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 2.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 3.8 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 1.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 3.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 6.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 5.2 GO:0043204 perikaryon(GO:0043204)
0.0 1.2 GO:1990752 microtubule end(GO:1990752)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 4.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 3.7 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.7 GO:0005844 polysome(GO:0005844)
0.0 2.1 GO:0045202 synapse(GO:0045202)
0.0 0.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 3.4 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 7.0 GO:0005769 early endosome(GO:0005769)
0.0 0.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 2.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.0 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 1.6 GO:0043679 axon terminus(GO:0043679)
0.0 3.7 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 1.5 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 9.5 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
1.3 5.2 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
1.2 3.7 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
1.2 3.6 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.8 4.0 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.6 1.8 GO:0098770 FBXO family protein binding(GO:0098770)
0.6 3.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.5 3.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.5 7.6 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.5 1.9 GO:0032427 GBD domain binding(GO:0032427)
0.5 1.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.4 7.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.4 3.0 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.4 4.5 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.4 1.5 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.4 2.2 GO:0004096 catalase activity(GO:0004096)
0.4 2.2 GO:0052842 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.4 2.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.4 1.1 GO:0016768 spermine synthase activity(GO:0016768)
0.3 3.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.3 1.0 GO:0033149 FFAT motif binding(GO:0033149)
0.3 2.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.3 2.4 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.3 3.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3 2.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.3 0.8 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 5.0 GO:0051400 BH domain binding(GO:0051400)
0.2 3.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.2 0.9 GO:0099609 microtubule lateral binding(GO:0099609)
0.2 1.5 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 0.6 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 4.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 0.6 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.2 2.1 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.8 GO:0009041 uridylate kinase activity(GO:0009041)
0.2 4.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 1.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 3.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 2.2 GO:0038132 neuregulin binding(GO:0038132)
0.2 1.7 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.5 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 0.6 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.9 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 2.0 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 2.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 2.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.1 6.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.9 GO:0089720 caspase binding(GO:0089720)
0.1 1.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.9 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.6 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 1.0 GO:0043426 MRF binding(GO:0043426)
0.1 4.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 1.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 1.4 GO:0071253 connexin binding(GO:0071253)
0.1 2.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.9 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 1.0 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 2.0 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 1.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 4.0 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 3.0 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 2.0 GO:0097602 cullin family protein binding(GO:0097602)
0.1 2.6 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 2.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 2.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.2 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1 0.5 GO:0097493 extracellular matrix constituent conferring elasticity(GO:0030023) structural molecule activity conferring elasticity(GO:0097493)
0.1 0.8 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 0.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 2.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 1.8 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 0.3 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 2.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 1.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 2.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.2 GO:0090541 MIT domain binding(GO:0090541)
0.1 4.8 GO:0070888 E-box binding(GO:0070888)
0.1 0.3 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.5 GO:0050815 phosphoserine binding(GO:0050815)
0.1 3.2 GO:0032452 histone demethylase activity(GO:0032452)
0.1 0.8 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 0.3 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.9 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 3.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 3.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 2.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 1.5 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 10.0 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.4 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 3.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.7 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 2.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 4.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.7 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 15.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 1.8 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 4.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 1.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 1.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 1.9 GO:0050699 WW domain binding(GO:0050699)
0.0 2.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.8 GO:0031690 adrenergic receptor binding(GO:0031690)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 1.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 2.1 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 1.0 GO:0008143 poly(A) binding(GO:0008143)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0005123 death receptor binding(GO:0005123)
0.0 6.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.0 GO:0043531 ADP binding(GO:0043531)
0.0 2.0 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001)
0.0 0.6 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 1.5 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 1.1 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.7 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 2.8 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 1.1 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 16.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.2 2.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 11.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 11.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 8.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 3.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 4.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 6.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 13.9 PID NOTCH PATHWAY Notch signaling pathway
0.1 4.0 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 4.4 PID CD40 PATHWAY CD40/CD40L signaling
0.1 4.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 3.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 2.4 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.1 1.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 3.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 2.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 3.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 4.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 3.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 8.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 4.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 5.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.0 PID FGF PATHWAY FGF signaling pathway
0.0 1.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 5.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.0 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.9 PID P73PATHWAY p73 transcription factor network
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.2 5.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 6.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 3.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 1.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.2 3.9 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 2.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 1.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 5.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 3.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 1.9 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 3.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 3.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 4.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 8.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 1.1 REACTOME SIGNALING BY FGFR IN DISEASE Genes involved in Signaling by FGFR in disease
0.1 1.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 9.4 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 3.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 4.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.9 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 4.3 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 1.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 4.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 3.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.4 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 1.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 1.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 3.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 3.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.1 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 3.0 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.1 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 1.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 1.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.0 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.1 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 2.1 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.8 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 4.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.5 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.4 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells