avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Name	miRBASE accession
hsa-miR-15a-5p Links miRBase	MIMAT0000068
hsa-miR-15b-5p Links miRBase	MIMAT0000417
hsa-miR-16-5p Links miRBase	MIMAT0000069
hsa-miR-195-5p Links miRBase	MIMAT0000461
hsa-miR-424-5p Links miRBase	MIMAT0001341
hsa-miR-497-5p Links miRBase	MIMAT0002820
hsa-miR-6838-5p Links miRBase	MIMAT0027578

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	3.8	GO:0060054	positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.7	2.0	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.6	1.8	GO:1904761	negative regulation of myofibroblast differentiation(GO:1904761)
0.6	1.7	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.6	1.7	GO:1904784	NLRP1 inflammasome complex assembly(GO:1904784)
0.5	1.6	GO:0021503	neural fold bending(GO:0021503)
0.5	1.5	GO:0003365	establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.5	1.4	GO:0002188	translation reinitiation(GO:0002188)
0.4	1.1	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.4	1.1	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.3	1.3	GO:0035616	histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.3	1.0	GO:0033341	regulation of collagen binding(GO:0033341)
0.3	1.0	GO:0060129	thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) renal vesicle induction(GO:0072034) regulation of testosterone biosynthetic process(GO:2000224)
0.3	1.3	GO:1903045	neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.3	2.8	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.3	0.9	GO:1903572	regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.3	0.9	GO:0034970	histone H3-R2 methylation(GO:0034970)
0.3	0.9	GO:0071109	superior temporal gyrus development(GO:0071109)
0.3	0.8	GO:0048633	negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.3	1.6	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.3	1.1	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.3	0.3	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
0.3	1.0	GO:0035978	mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.3	0.3	GO:0046619	optic placode formation involved in camera-type eye formation(GO:0046619)
0.3	0.8	GO:0021722	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2	1.5	GO:0060005	vestibular reflex(GO:0060005)
0.2	4.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.2	0.4	GO:2001038	regulation of cellular response to drug(GO:2001038)
0.2	4.9	GO:0071481	cellular response to X-ray(GO:0071481)
0.2	0.8	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.2	0.6	GO:1990108	protein linear deubiquitination(GO:1990108)
0.2	0.6	GO:0007538	primary sex determination(GO:0007538)
0.2	3.1	GO:0015074	DNA integration(GO:0015074)
0.2	0.6	GO:0031106	septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.2	0.6	GO:0060697	positive regulation of phospholipid catabolic process(GO:0060697)
0.2	0.9	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.2	0.7	GO:1904502	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.2	0.5	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.2	1.2	GO:0051012	microtubule sliding(GO:0051012)
0.2	0.5	GO:1904562	phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.2	0.5	GO:0061386	closure of optic fissure(GO:0061386)
0.2	0.5	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1	2.2	GO:0007028	cytoplasm organization(GO:0007028)
0.1	0.7	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.1	0.4	GO:0097676	histone H3-K36 dimethylation(GO:0097676)
0.1	0.9	GO:0061084	regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1	0.9	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	3.1	GO:0097264	self proteolysis(GO:0097264)
0.1	1.4	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.1	0.6	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1	0.4	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1	0.8	GO:0035947	regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1	0.5	GO:1904808	regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.1	0.8	GO:0015798	myo-inositol transport(GO:0015798)
0.1	0.7	GO:0018032	protein amidation(GO:0018032)
0.1	0.4	GO:0071504	cellular response to heparin(GO:0071504)
0.1	0.4	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1	1.3	GO:0060174	limb bud formation(GO:0060174)
0.1	0.9	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1	0.9	GO:0060017	parathyroid gland development(GO:0060017)
0.1	1.3	GO:0061734	parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.1	0.5	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.1	0.8	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.1	1.4	GO:0060613	fat pad development(GO:0060613)
0.1	0.7	GO:0022614	membrane to membrane docking(GO:0022614)
0.1	0.8	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1	0.3	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1	0.3	GO:0061534	gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1	0.8	GO:0046604	positive regulation of mitotic centrosome separation(GO:0046604)
0.1	1.0	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	1.6	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.1	3.3	GO:0021542	dentate gyrus development(GO:0021542)
0.1	0.5	GO:0001555	oocyte growth(GO:0001555)
0.1	2.5	GO:0002347	response to tumor cell(GO:0002347)
0.1	0.5	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
0.1	0.6	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1	0.3	GO:1904978	regulation of endosome organization(GO:1904978)
0.1	0.4	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1	0.6	GO:2000490	negative regulation of hepatic stellate cell activation(GO:2000490)
0.1	0.4	GO:0002528	regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1	1.0	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.1	1.1	GO:0070257	positive regulation of mucus secretion(GO:0070257)
0.1	0.3	GO:0016240	autophagosome docking(GO:0016240)
0.1	3.3	GO:0060441	epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.1	0.6	GO:0030099	myeloid cell differentiation(GO:0030099)
0.1	0.1	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.1	0.4	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1	0.6	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.1	1.7	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.1	0.2	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1	1.2	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	0.3	GO:0071874	cellular response to norepinephrine stimulus(GO:0071874)
0.1	0.6	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1	0.7	GO:0016584	nucleosome positioning(GO:0016584)
0.1	1.5	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1	0.3	GO:0089709	histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.1	0.8	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	0.6	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.1	0.2	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	1.0	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.1	0.2	GO:0002644	negative regulation of tolerance induction(GO:0002644)
0.1	1.0	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.1	0.3	GO:0036302	atrioventricular canal development(GO:0036302)
0.1	0.7	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.1	0.5	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.1	0.3	GO:0060011	Sertoli cell proliferation(GO:0060011)
0.1	0.8	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1	0.7	GO:0051044	cleavage furrow formation(GO:0036089) positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	0.3	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1	0.3	GO:0051029	rRNA transport(GO:0051029)
0.1	0.4	GO:1904885	beta-catenin destruction complex assembly(GO:1904885)
0.1	0.4	GO:1903895	negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.1	0.3	GO:0000255	allantoin metabolic process(GO:0000255)
0.1	0.2	GO:0019085	early viral transcription(GO:0019085)
0.1	1.2	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.1	0.2	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.1	0.5	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0	0.2	GO:0044010	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.0	0.8	GO:0035372	protein localization to microtubule(GO:0035372)
0.0	1.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.7	GO:0097012	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0	0.2	GO:0051413	response to cortisone(GO:0051413)
0.0	0.2	GO:0001828	inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0	2.0	GO:0019054	modulation by virus of host process(GO:0019054)
0.0	0.7	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.6	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.0	0.4	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.5	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.6	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	1.0	GO:0045116	protein neddylation(GO:0045116)
0.0	1.2	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.4	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	0.6	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.3	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.2	GO:0016094	polyprenol biosynthetic process(GO:0016094)
0.0	0.2	GO:0070459	prolactin secretion(GO:0070459)
0.0	0.4	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.9	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.6	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.2	GO:0061739	protein lipidation involved in autophagosome assembly(GO:0061739)
0.0	0.3	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.0	0.2	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0	0.3	GO:0060136	embryonic process involved in female pregnancy(GO:0060136) response to interleukin-15(GO:0070672)
0.0	0.8	GO:0086016	AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0	0.9	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.0	0.6	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.1	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0	0.4	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	1.0	GO:0006825	copper ion transport(GO:0006825)
0.0	0.3	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.7	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.0	0.2	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.2	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0	0.3	GO:0052428	modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0	0.6	GO:0038092	nodal signaling pathway(GO:0038092)
0.0	0.6	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.4	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	0.3	GO:0035494	SNARE complex disassembly(GO:0035494)
0.0	0.5	GO:0033227	dsRNA transport(GO:0033227)
0.0	0.1	GO:0035617	stress granule disassembly(GO:0035617)
0.0	0.1	GO:0018283	metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.0	1.4	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	2.7	GO:2001238	positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0	0.4	GO:0070141	response to UV-A(GO:0070141)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.3	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.0	GO:0090402	oncogene-induced cell senescence(GO:0090402)
0.0	0.7	GO:0046519	sphingoid metabolic process(GO:0046519)
0.0	0.5	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0	0.4	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	1.5	GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0	0.3	GO:0051438	regulation of ubiquitin-protein transferase activity(GO:0051438)
0.0	0.5	GO:0016926	protein desumoylation(GO:0016926)
0.0	0.7	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0	1.1	GO:0030199	collagen fibril organization(GO:0030199)
0.0	1.6	GO:0031648	protein destabilization(GO:0031648)
0.0	1.0	GO:0014059	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0	1.0	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
0.0	0.5	GO:0010663	positive regulation of striated muscle cell apoptotic process(GO:0010663) positive regulation of cardiac muscle cell apoptotic process(GO:0010666)
0.0	0.9	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.0	0.3	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0	0.3	GO:0002098	tRNA wobble uridine modification(GO:0002098)
0.0	0.4	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0010635	regulation of mitochondrial fusion(GO:0010635)
0.0	0.6	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.3	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.9	GO:0006986	response to unfolded protein(GO:0006986)
0.0	1.0	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0	0.5	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.5	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	1.1	GO:0046039	GTP metabolic process(GO:0046039)
0.0	0.4	GO:0060736	prostate gland growth(GO:0060736)
0.0	0.2	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.5	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.2	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0	0.1	GO:1900276	regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0	1.6	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.1	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.9	GO:1902592	viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.0	3.6	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0	0.2	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.0	0.1	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.0	0.0	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.3	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.3	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.4	GO:0000338	protein deneddylation(GO:0000338)
0.0	0.2	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	3.1	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0	1.5	GO:0045652	regulation of megakaryocyte differentiation(GO:0045652)
0.0	0.1	GO:0001878	response to yeast(GO:0001878)
0.0	0.5	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.4	GO:0090344	negative regulation of cell aging(GO:0090344)
0.0	0.1	GO:1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0	0.1	GO:0038033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0	0.7	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.0	0.5	GO:0000466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0	0.3	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.5	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.0	1.0	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.3	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	1.8	GO:1903363	negative regulation of cellular protein catabolic process(GO:1903363)
0.0	0.7	GO:0007050	cell cycle arrest(GO:0007050)
0.0	0.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.4	GO:0040013	negative regulation of locomotion(GO:0040013)
0.0	0.3	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.5	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.3	GO:0039536	negative regulation of RIG-I signaling pathway(GO:0039536)
0.0	0.1	GO:0051013	microtubule severing(GO:0051013)
0.0	0.1	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.1	GO:0071484	cellular response to light intensity(GO:0071484)
0.0	0.1	GO:0060152	peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.0	0.1	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.3	GO:0046777	protein autophosphorylation(GO:0046777)
0.0	1.1	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0	1.9	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.8	GO:0097485	neuron projection guidance(GO:0097485)
0.0	0.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.2	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.0	1.3	GO:0031398	positive regulation of protein ubiquitination(GO:0031398)
0.0	0.3	GO:0045794	negative regulation of cell volume(GO:0045794)
0.0	0.0	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.2	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.1	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.5	GO:0042026	protein refolding(GO:0042026)
0.0	0.4	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.3	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	2.1	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.2	GO:0019388	galactose catabolic process(GO:0019388)
0.0	0.1	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.8	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.0	1.2	GO:0002223	stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0	0.4	GO:0045581	negative regulation of T cell differentiation(GO:0045581)
0.0	0.0	GO:1904647	response to rotenone(GO:1904647)
0.0	0.4	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0	0.1	GO:0048712	negative regulation of astrocyte differentiation(GO:0048712)
0.0	0.2	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0	0.2	GO:0042534	tumor necrosis factor biosynthetic process(GO:0042533) regulation of tumor necrosis factor biosynthetic process(GO:0042534)
0.0	0.0	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.3	GO:0035066	positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.6	GO:0000186	activation of MAPKK activity(GO:0000186)
0.0	0.1	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.4	GO:0070932	histone H3 deacetylation(GO:0070932)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.2	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	0.4	GO:0016239	positive regulation of macroautophagy(GO:0016239)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	4.6	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.5	0.5	GO:0043260	laminin-11 complex(GO:0043260)
0.5	1.4	GO:0043614	multi-eIF complex(GO:0043614)
0.4	1.2	GO:0005595	collagen type XII trimer(GO:0005595)
0.4	2.0	GO:0035838	growing cell tip(GO:0035838)
0.2	1.7	GO:0072558	NLRP1 inflammasome complex(GO:0072558)
0.2	0.8	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2	0.7	GO:0031213	RSF complex(GO:0031213)
0.2	0.8	GO:0071149	TEAD-2-YAP complex(GO:0071149)
0.2	1.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.1	2.1	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.7	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.1	0.4	GO:0031592	centrosomal corona(GO:0031592)
0.1	1.3	GO:0030314	junctional membrane complex(GO:0030314)
0.1	1.0	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1	0.4	GO:1990425	ryanodine receptor complex(GO:1990425)
0.1	0.3	GO:0070195	growth hormone receptor complex(GO:0070195)
0.1	1.0	GO:0016589	NURF complex(GO:0016589)
0.1	1.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	1.3	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	1.2	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	0.3	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.1	0.6	GO:0005826	actomyosin contractile ring(GO:0005826)
0.1	0.2	GO:0002944	cyclin K-CDK12 complex(GO:0002944)
0.1	2.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.6	GO:0031415	NatA complex(GO:0031415)
0.1	1.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.5	GO:0033553	rDNA heterochromatin(GO:0033553)
0.1	1.0	GO:0071986	Ragulator complex(GO:0071986)
0.1	0.5	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	0.2	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
0.1	0.3	GO:0002081	outer acrosomal membrane(GO:0002081)
0.1	1.6	GO:0042588	zymogen granule(GO:0042588)
0.1	0.3	GO:0032449	CBM complex(GO:0032449)
0.1	0.7	GO:0042788	polysomal ribosome(GO:0042788)
0.1	1.0	GO:0033391	chromatoid body(GO:0033391)
0.1	0.3	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.1	0.9	GO:0000813	ESCRT I complex(GO:0000813)
0.1	0.9	GO:1990909	Wnt signalosome(GO:1990909)
0.1	3.7	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0031379	RNA-directed RNA polymerase complex(GO:0031379)
0.0	1.0	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.2	GO:0070931	Golgi-associated vesicle lumen(GO:0070931)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.4	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.9	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.7	GO:0032059	bleb(GO:0032059)
0.0	7.4	GO:0016605	PML body(GO:0016605)
0.0	0.4	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	1.8	GO:0016592	mediator complex(GO:0016592)
0.0	1.2	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.6	GO:0061200	clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0	0.3	GO:0002177	manchette(GO:0002177)
0.0	4.5	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.7	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	2.0	GO:0008180	COP9 signalosome(GO:0008180)
0.0	1.1	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.4	GO:0030478	actin cap(GO:0030478)
0.0	0.3	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	0.6	GO:0031045	dense core granule(GO:0031045)
0.0	0.4	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.6	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.0	0.1	GO:0035370	UBC13-UEV1A complex(GO:0035370)
0.0	0.5	GO:0097227	sperm annulus(GO:0097227)
0.0	0.6	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.2	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.0	0.1	GO:0030992	intraciliary transport particle B(GO:0030992)
0.0	1.6	GO:0031941	filamentous actin(GO:0031941)
0.0	0.5	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	1.0	GO:0030425	dendrite(GO:0030425)
0.0	2.9	GO:0005811	lipid particle(GO:0005811)
0.0	0.9	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	1.4	GO:0005813	centrosome(GO:0005813)
0.0	0.1	GO:0008537	proteasome activator complex(GO:0008537)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.5	GO:0000346	transcription export complex(GO:0000346)
0.0	1.7	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	1.0	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	1.2	GO:0016020	membrane(GO:0016020)
0.0	2.7	GO:0005643	nuclear pore(GO:0005643)
0.0	0.8	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.3	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.3	GO:0030914	STAGA complex(GO:0030914)
0.0	1.2	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.6	GO:0016580	Sin3 complex(GO:0016580)
0.0	2.4	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.5	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.2	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	1.7	GO:0005923	bicellular tight junction(GO:0005923)
0.0	0.5	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.1	GO:0061617	MICOS complex(GO:0061617)
0.0	0.1	GO:0043235	receptor complex(GO:0043235)
0.0	0.2	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	3.3	GO:0001650	fibrillar center(GO:0001650)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.3	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0	0.3	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.8	GO:0072686	mitotic spindle(GO:0072686)
0.0	1.6	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	1.4	GO:0030666	endocytic vesicle membrane(GO:0030666)
0.0	1.6	GO:0070469	respiratory chain(GO:0070469)
0.0	1.4	GO:0031970	organelle envelope lumen(GO:0031970)
0.0	1.6	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.2	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.6	GO:0048471	perinuclear region of cytoplasm(GO:0048471)
0.0	0.2	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	0.3	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.0	0.7	GO:0043034	costamere(GO:0043034)
0.0	0.4	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.0	0.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	1.4	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.0	0.7	GO:0005801	cis-Golgi network(GO:0005801)
0.0	0.5	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.1	GO:0042383	sarcolemma(GO:0042383)
0.0	0.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.4	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.3	GO:0030118	clathrin coat(GO:0030118)
0.0	1.0	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.5	2.0	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.3	0.8	GO:0005365	myo-inositol transmembrane transporter activity(GO:0005365)
0.3	0.8	GO:0098770	FBXO family protein binding(GO:0098770)
0.3	1.0	GO:0035501	MH1 domain binding(GO:0035501)
0.3	0.8	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2	1.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2	5.3	GO:0048018	receptor agonist activity(GO:0048018)
0.2	0.6	GO:0033149	FFAT motif binding(GO:0033149)
0.2	1.3	GO:0061649	ubiquitinated histone binding(GO:0061649)
0.2	1.6	GO:0043426	MRF binding(GO:0043426)
0.2	2.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.2	0.5	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.2	0.5	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.2	0.7	GO:0032184	SUMO polymer binding(GO:0032184)
0.2	1.6	GO:0038049	transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.2	0.6	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.1	0.6	GO:0009041	uridylate kinase activity(GO:0009041)
0.1	0.6	GO:0047888	fatty acid peroxidase activity(GO:0047888)
0.1	1.2	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	0.4	GO:0008193	tRNA guanylyltransferase activity(GO:0008193)
0.1	0.8	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1	0.3	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.1	1.5	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.1	0.3	GO:0047676	arachidonate-CoA ligase activity(GO:0047676)
0.1	0.8	GO:0070728	leucine binding(GO:0070728)
0.1	0.7	GO:0004504	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1	0.8	GO:0043813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.1	0.4	GO:0045322	unmethylated CpG binding(GO:0045322)
0.1	1.2	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1	0.8	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1	1.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1	0.4	GO:0071209	U7 snRNA binding(GO:0071209)
0.1	1.2	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.1	0.4	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.1	0.7	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1	0.8	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1	0.5	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1	0.2	GO:0016768	spermine synthase activity(GO:0016768)
0.1	1.1	GO:0031386	protein tag(GO:0031386)
0.1	0.4	GO:0010465	nerve growth factor receptor activity(GO:0010465)
0.1	2.2	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1	0.7	GO:0061665	SUMO ligase activity(GO:0061665)
0.1	0.6	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	0.4	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.1	0.6	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.1	0.4	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
0.1	2.0	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	0.3	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.1	0.9	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1	1.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1	0.3	GO:0004461	lactose synthase activity(GO:0004461)
0.1	1.7	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.1	3.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.1	0.7	GO:0035198	miRNA binding(GO:0035198)
0.1	0.9	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.1	0.2	GO:0090541	MIT domain binding(GO:0090541)
0.1	3.7	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.5	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1	2.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.1	1.3	GO:0045499	chemorepellent activity(GO:0045499)
0.1	0.8	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.1	0.7	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.1	0.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.1	0.2	GO:0031177	3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-acetyltransferase activity(GO:0016418) phosphopantetheine binding(GO:0031177)
0.1	0.9	GO:0000182	rDNA binding(GO:0000182)
0.1	0.4	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1	3.0	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.1	0.2	GO:0036033	mediator complex binding(GO:0036033)
0.1	0.3	GO:0070644	vitamin D response element binding(GO:0070644)
0.1	1.4	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.2	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.0	0.6	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	1.2	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.3	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	2.9	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.6	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	1.5	GO:0051428	peptide hormone receptor binding(GO:0051428)
0.0	0.9	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.8	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.3	GO:1901474	azole transmembrane transporter activity(GO:1901474)
0.0	1.1	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.3	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.4	GO:0043515	kinetochore binding(GO:0043515)
0.0	1.9	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	1.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	1.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.6	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.3	GO:0047522	13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0	0.3	GO:0072320	volume-sensitive chloride channel activity(GO:0072320)
0.0	0.2	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.2	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.9	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.2	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
0.0	0.9	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.6	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.2	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
0.0	0.3	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.9	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.3	GO:0047493	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0	0.7	GO:0045309	protein phosphorylated amino acid binding(GO:0045309)
0.0	1.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.4	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.9	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.6	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	2.0	GO:0050699	WW domain binding(GO:0050699)
0.0	0.1	GO:0031071	cysteine desulfurase activity(GO:0031071)
0.0	0.3	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.4	GO:0089720	caspase binding(GO:0089720)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:1904854	proteasome core complex binding(GO:1904854)
0.0	1.2	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	0.3	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.8	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	2.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.5	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.4	GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0	1.2	GO:0001671	ATPase activator activity(GO:0001671)
0.0	0.1	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0	0.2	GO:0016936	galactoside binding(GO:0016936)
0.0	0.5	GO:0001164	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.9	GO:0031489	myosin V binding(GO:0031489)
0.0	0.2	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	1.6	GO:0003700	transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	0.2	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	1.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.3	GO:0003712	transcription cofactor activity(GO:0003712) transcription coactivator activity(GO:0003713)
0.0	0.6	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.2	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.4	GO:0051400	BH domain binding(GO:0051400)
0.0	0.2	GO:0030628	pre-mRNA 3'-splice site binding(GO:0030628)
0.0	0.3	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.2	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0	1.0	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	1.0	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	1.3	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	2.0	GO:0005044	scavenger receptor activity(GO:0005044)
0.0	1.0	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.0	1.0	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.2	GO:0010385	double-stranded methylated DNA binding(GO:0010385)
0.0	0.4	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.1	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.3	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.4	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.4	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.6	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.3	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.2	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.5	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0001034	RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0	1.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.7	GO:0000146	microfilament motor activity(GO:0000146)
0.0	0.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.5	GO:0043015	gamma-tubulin binding(GO:0043015)
0.0	0.7	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.2	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	1.8	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	1.6	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0	0.4	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.1	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0	0.1	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.5	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.0	0.5	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.5	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.3	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.2	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.3	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.3	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	1.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.7	GO:0030507	spectrin binding(GO:0030507)
0.0	0.3	GO:0016504	peptidase activator activity(GO:0016504)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.1	3.5	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.1	3.7	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.1	5.7	PID NECTIN PATHWAY	Nectin adhesion pathway
0.1	3.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	1.7	PID S1P S1P1 PATHWAY	S1P1 pathway
0.1	4.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.1	2.8	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	0.4	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	2.8	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	1.0	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.7	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	1.1	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	1.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	1.4	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	1.7	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	1.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	2.1	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	2.7	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.5	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.0	1.1	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	1.1	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	6.3	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	2.0	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.0	0.2	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.5	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.7	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.6	PID MYC PATHWAY	C-MYC pathway
0.0	1.2	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.0	0.3	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	2.0	PID NOTCH PATHWAY	Notch signaling pathway
0.0	2.3	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.0	0.6	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	1.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	0.2	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.4	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.5	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.6	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.8	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.1	3.3	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.7	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.1	1.4	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	1.6	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	2.3	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.1	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1	2.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	1.5	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.1	1.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	1.2	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	0.8	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1	1.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	4.2	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.1	1.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	1.7	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	1.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	6.2	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	1.8	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	1.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.4	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.0	0.8	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	2.6	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	1.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.9	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.9	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.9	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	2.5	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	1.4	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	1.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	2.7	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.7	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	1.1	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.9	REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS	Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0	3.7	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	0.4	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.4	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.3	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.5	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	0.1	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events
0.0	1.4	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	1.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	1.5	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.6	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.4	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	0.4	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	1.2	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	4.2	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	0.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.3	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.1	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor