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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for AGUGCAA

Z-value: 1.41

Motif logo

miRNA associated with seed AGUGCAA

NamemiRBASE accession
MIMAT0000425
MIMAT0000691
MIMAT0000688
MIMAT0004958
MIMAT0003885
MIMAT0018088
MIMAT0016844

Activity profile of AGUGCAA motif

Sorted Z-values of AGUGCAA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AGUGCAA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.3 1.3 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.3 1.9 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 0.7 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.2 0.7 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 0.6 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.2 0.9 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.2 1.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 0.8 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 1.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.2 1.0 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.2 0.8 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.4 GO:0003032 detection of oxygen(GO:0003032)
0.1 0.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.6 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 1.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 1.3 GO:0030242 pexophagy(GO:0030242)
0.1 2.3 GO:0015693 magnesium ion transport(GO:0015693)
0.1 0.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.4 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.4 GO:1905073 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.1 0.6 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.3 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.9 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.6 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 0.6 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 1.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.1 0.9 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 1.0 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.4 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 0.4 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.5 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.3 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.1 0.2 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.1 0.4 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.4 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 0.3 GO:0006408 snRNA export from nucleus(GO:0006408)
0.1 0.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.4 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.1 0.6 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 1.4 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.2 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.2 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.1 0.3 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.2 GO:0035188 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1 0.4 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.1 0.5 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.1 0.3 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.6 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.8 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.3 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.5 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.4 GO:0071484 cellular response to light intensity(GO:0071484)
0.0 0.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.9 GO:0044320 cellular response to leptin stimulus(GO:0044320)
0.0 0.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.2 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.4 GO:0097338 response to clozapine(GO:0097338)
0.0 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.7 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.4 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.0 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.2 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.3 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.3 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0050904 diapedesis(GO:0050904)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.9 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.5 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.0 0.1 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.0 0.4 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.8 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.3 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 0.3 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.4 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 1.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 1.0 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.3 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.6 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.5 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.4 GO:0060242 contact inhibition(GO:0060242)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 1.0 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.6 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.0 0.5 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.5 GO:2000810 regulation of bicellular tight junction assembly(GO:2000810)
0.0 0.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.4 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.4 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:0051029 rRNA transport(GO:0051029)
0.0 0.2 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.5 GO:0033622 integrin activation(GO:0033622)
0.0 0.3 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.3 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.3 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.0 0.1 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.0 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0097149 centralspindlin complex(GO:0097149)
0.2 0.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.6 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.1 0.4 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.4 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.2 GO:0097227 sperm annulus(GO:0097227)
0.1 0.5 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 1.8 GO:0090543 Flemming body(GO:0090543)
0.1 1.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.8 GO:0030905 retromer, tubulation complex(GO:0030905)
0.1 0.2 GO:0034657 GID complex(GO:0034657)
0.1 1.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0031417 NatC complex(GO:0031417)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 0.2 GO:0075341 host cell PML body(GO:0075341)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.3 GO:0031905 early endosome lumen(GO:0031905)
0.1 0.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 0.9 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.3 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 1.1 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.4 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.8 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.5 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0030891 VCB complex(GO:0030891)
0.0 0.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 1.5 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.4 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 0.6 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.7 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.8 GO:0031941 filamentous actin(GO:0031941)
0.0 1.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.5 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.8 GO:0001772 immunological synapse(GO:0001772)
0.0 0.2 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.2 1.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 0.5 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.2 0.5 GO:0071633 dihydroceramidase activity(GO:0071633)
0.2 0.7 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 0.9 GO:0004882 androgen receptor activity(GO:0004882)
0.2 0.5 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 1.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:0050405 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1 1.0 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.7 GO:1990460 leptin receptor binding(GO:1990460)
0.1 1.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.5 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.6 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.9 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.5 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.4 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.9 GO:1904929 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 2.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 0.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 1.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.2 GO:0019961 interferon binding(GO:0019961)
0.1 0.7 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 2.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.3 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.4 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.8 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 1.0 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.2 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.3 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.4 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.3 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.4 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 2.4 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 1.1 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0016174 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) NAD(P)H oxidase activity(GO:0016174)
0.0 1.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.4 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.5 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.7 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.5 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 1.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.8 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.7 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.2 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 2.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 1.1 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.1 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.2 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 2.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 1.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.3 REACTOME KINESINS Genes involved in Kinesins
0.0 0.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.0 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME PKB MEDIATED EVENTS Genes involved in PKB-mediated events
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins