ISMARA results: AHR

Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation

Downloads

Results for AHR_ARNT2

Z-value: 0.47

Motif logo

Transcription factors associated with AHR_ARNT2

Gene Symbol	Gene ID	Gene Info
AHR Ensembl NCBI GeneCards UniProt	ENSG00000106546.8	aryl hydrocarbon receptor
ARNT2 Ensembl NCBI GeneCards UniProt	ENSG00000172379.14	aryl hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
AHR	hg19_v2_chr7_+_17338239_17338262	-0.64	2.2e-03	Click!
ARNT2	hg19_v2_chr15_+_80696666_80696700	0.46	4.0e-02	Click!

Activity profile of AHR_ARNT2 motif

Sorted Z-values of AHR_ARNT2 motif

No targets for AHR_ARNT2

Network of associatons between targets according to the STRING database.

First level regulatory network of AHR_ARNT2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.5	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.0	1.3	GO:0070126	mitochondrial translational termination(GO:0070126)
0.0	1.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.9	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.8	GO:0070982	L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.0	0.8	GO:0015886	heme transport(GO:0015886)
0.0	0.8	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.8	GO:0070207	protein homotrimerization(GO:0070207)
0.1	0.7	GO:1902462	regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1	0.7	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)

Showing 1 to 10 of 384 entries

Gene overrepresentation in cellular_component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.6	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	1.3	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	1.3	GO:0015935	small ribosomal subunit(GO:0015935)
0.0	0.8	GO:0005761	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0	0.7	GO:0031143	pseudopodium(GO:0031143)
0.0	0.6	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.6	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.1	0.5	GO:1990031	pinceau fiber(GO:1990031)
0.1	0.5	GO:0098536	deuterosome(GO:0098536)
0.1	0.5	GO:0000408	EKC/KEOPS complex(GO:0000408)

Showing 1 to 10 of 109 entries

Gene overrepresentation in molecular_function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.7	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	1.1	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3	0.9	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
0.1	0.8	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0	0.8	GO:0039706	co-receptor binding(GO:0039706)
0.0	0.8	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.8	GO:0000030	mannosyltransferase activity(GO:0000030)
0.0	0.8	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.7	GO:0008483	transaminase activity(GO:0008483)
0.0	0.7	GO:0050431	transforming growth factor beta binding(GO:0050431)

Showing 1 to 10 of 234 entries

Gene overrepresentation in C2:CP category:

Search:

Show entries

Total log-likelihood	Term	Description
1.4	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	PID REELIN PATHWAY	Reelin signaling pathway
0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	PID S1P S1P3 PATHWAY	S1P3 pathway

Showing 1 to 8 of 8 entries

Gene overrepresentation in C2:CP:REACTOME category:

Search:

Show entries

Total log-likelihood	Term	Description
2.6	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
1.7	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
1.4	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
1.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
1.1	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.9	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.9	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.8	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.8	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism

Showing 1 to 10 of 35 entries

Results for AHR_ARNT2

Z-value: 0.47

Motif logo

Transcription factors associated with AHR_ARNT2

Activity-expression correlation:

Activity profile of AHR_ARNT2 motif

Sorted Z-values of AHR_ARNT2 motif

No targets for AHR_ARNT2

Network of associatons between targets according to the STRING database.

First level regulatory network of AHR_ARNT2

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: