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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for ARID5A
Z-value: 1.34
Motif logo
Transcription factors associated with ARID5A
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ARID5A
|
ENSG00000196843.11 | AT-rich interaction domain 5A |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ARID5A | hg19_v2_chr2_+_97202480_97202499 | -0.32 | 1.6e-01 | Click! |
Activity profile of ARID5A motif
Sorted Z-values of ARID5A motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ARID5A
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.2 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.5 | 1.6 | GO:1904328 | regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) |
| 0.4 | 1.1 | GO:0031247 | actin rod assembly(GO:0031247) |
| 0.3 | 2.4 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 0.3 | 0.9 | GO:1902173 | negative regulation of keratinocyte apoptotic process(GO:1902173) |
| 0.3 | 1.4 | GO:1903285 | negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.2 | 1.0 | GO:0060447 | bud outgrowth involved in lung branching(GO:0060447) |
| 0.2 | 1.4 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.2 | 1.0 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.2 | 0.6 | GO:0007113 | endomitotic cell cycle(GO:0007113) |
| 0.2 | 0.5 | GO:2000502 | negative regulation of natural killer cell chemotaxis(GO:2000502) |
| 0.2 | 1.0 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 0.2 | 0.5 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
| 0.2 | 0.5 | GO:0072616 | interleukin-18 secretion(GO:0072616) |
| 0.1 | 0.7 | GO:0016095 | polyprenol catabolic process(GO:0016095) |
| 0.1 | 2.5 | GO:0010759 | positive regulation of macrophage chemotaxis(GO:0010759) |
| 0.1 | 0.5 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.1 | 1.0 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.1 | 1.0 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 0.3 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
| 0.1 | 0.5 | GO:0003409 | optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623) |
| 0.1 | 1.4 | GO:0045919 | positive regulation of cytolysis(GO:0045919) |
| 0.1 | 0.4 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
| 0.1 | 0.6 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.1 | 0.3 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.1 | 0.7 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.1 | 0.5 | GO:1900827 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.1 | 1.9 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.1 | 1.3 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.1 | 0.4 | GO:2000639 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 0.1 | 0.2 | GO:0007439 | ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611) |
| 0.1 | 1.0 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.1 | 0.6 | GO:0072734 | response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734) |
| 0.1 | 0.6 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 0.1 | 0.3 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.1 | 0.5 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.1 | 0.2 | GO:0060152 | peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152) |
| 0.1 | 0.3 | GO:0038155 | interleukin-23-mediated signaling pathway(GO:0038155) |
| 0.1 | 0.5 | GO:0043622 | cortical microtubule organization(GO:0043622) |
| 0.1 | 0.3 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
| 0.1 | 1.0 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 0.1 | 0.1 | GO:0080171 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.1 | 0.4 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.1 | 0.8 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.1 | 2.4 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.1 | 0.7 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 0.1 | 0.2 | GO:0021503 | neural fold bending(GO:0021503) |
| 0.1 | 0.6 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.0 | 0.3 | GO:1904383 | response to sodium phosphate(GO:1904383) |
| 0.0 | 0.5 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.0 | 0.4 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.0 | 1.2 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.0 | 0.2 | GO:0008050 | female courtship behavior(GO:0008050) |
| 0.0 | 0.2 | GO:1904158 | axonemal central apparatus assembly(GO:1904158) |
| 0.0 | 0.3 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.0 | 0.1 | GO:0098507 | polynucleotide 5' dephosphorylation(GO:0098507) |
| 0.0 | 0.1 | GO:0072428 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.0 | 0.2 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.0 | 1.1 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.0 | 0.7 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 0.2 | GO:0010909 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 0.0 | 0.3 | GO:0034285 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
| 0.0 | 0.2 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.0 | 0.3 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 0.0 | 0.1 | GO:0001970 | positive regulation of activation of membrane attack complex(GO:0001970) |
| 0.0 | 0.2 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 0.0 | 0.2 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.0 | 0.8 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 0.0 | 0.1 | GO:0009405 | pathogenesis(GO:0009405) |
| 0.0 | 0.6 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.0 | 0.5 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.2 | GO:1901315 | negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.0 | 2.1 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.0 | 0.2 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.0 | 0.3 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.0 | 3.2 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.0 | 1.3 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.3 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.0 | 0.7 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 0.4 | GO:0034587 | piRNA metabolic process(GO:0034587) |
| 0.0 | 0.6 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.0 | 1.1 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.3 | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) |
| 0.0 | 0.2 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.0 | 0.2 | GO:0006987 | activation of signaling protein activity involved in unfolded protein response(GO:0006987) |
| 0.0 | 0.3 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.0 | 0.1 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 0.0 | 0.2 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.0 | 0.1 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.0 | 0.3 | GO:0051170 | nuclear import(GO:0051170) |
| 0.0 | 0.2 | GO:0051026 | chiasma assembly(GO:0051026) |
| 0.0 | 0.2 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
| 0.0 | 2.1 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.2 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 0.0 | 0.5 | GO:0034389 | lipid particle organization(GO:0034389) |
| 0.0 | 0.4 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.0 | 0.7 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.0 | 0.7 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.0 | 0.6 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.0 | 0.1 | GO:0030222 | eosinophil differentiation(GO:0030222) |
| 0.0 | 0.4 | GO:0045899 | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899) |
| 0.0 | 0.2 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.0 | 0.4 | GO:0036315 | cellular response to sterol(GO:0036315) |
| 0.0 | 0.1 | GO:0003185 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) |
| 0.0 | 0.5 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.0 | 0.1 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.0 | 1.2 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
| 0.0 | 0.3 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.0 | 0.1 | GO:0009804 | coumarin metabolic process(GO:0009804) |
| 0.0 | 0.1 | GO:0006198 | cAMP catabolic process(GO:0006198) cyclic nucleotide catabolic process(GO:0009214) |
| 0.0 | 0.5 | GO:0032620 | interleukin-17 production(GO:0032620) |
| 0.0 | 0.4 | GO:0045087 | innate immune response(GO:0045087) |
| 0.0 | 0.4 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.1 | GO:0034627 | 'de novo' NAD biosynthetic process(GO:0034627) |
| 0.0 | 0.2 | GO:0007597 | blood coagulation, intrinsic pathway(GO:0007597) |
| 0.0 | 0.2 | GO:0010839 | negative regulation of keratinocyte proliferation(GO:0010839) |
| 0.0 | 0.1 | GO:0070269 | pyroptosis(GO:0070269) |
| 0.0 | 0.1 | GO:0043696 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
| 0.0 | 0.1 | GO:0034144 | negative regulation of toll-like receptor 4 signaling pathway(GO:0034144) |
| 0.0 | 0.1 | GO:0070543 | response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
| 0.0 | 0.3 | GO:0046164 | alcohol catabolic process(GO:0046164) |
| 0.0 | 0.3 | GO:0035090 | maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.0 | 0.6 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.0 | 1.2 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 0.1 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
| 0.0 | 1.1 | GO:0016266 | O-glycan processing(GO:0016266) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 0.6 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.2 | 2.0 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.2 | 1.0 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.2 | 2.1 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.1 | 2.5 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 1.6 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.1 | 0.4 | GO:1990923 | PET complex(GO:1990923) |
| 0.1 | 0.6 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.1 | 0.3 | GO:0097635 | extrinsic component of autophagosome membrane(GO:0097635) |
| 0.1 | 0.2 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 0.1 | 0.7 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.1 | 0.6 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.1 | 1.0 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.1 | 0.4 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.1 | 0.2 | GO:1990745 | EARP complex(GO:1990745) |
| 0.1 | 0.3 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.1 | 0.3 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
| 0.0 | 1.1 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.5 | GO:0036128 | CatSper complex(GO:0036128) |
| 0.0 | 0.7 | GO:0098647 | collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647) |
| 0.0 | 1.1 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 0.2 | GO:0005594 | collagen type IX trimer(GO:0005594) |
| 0.0 | 1.5 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.3 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.3 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.0 | 1.0 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.2 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.0 | 0.1 | GO:0034515 | proteasome storage granule(GO:0034515) |
| 0.0 | 0.4 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.0 | 0.7 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 0.4 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.0 | 0.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.2 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.5 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.0 | 1.4 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 0.2 | GO:0001939 | female pronucleus(GO:0001939) |
| 0.0 | 1.6 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 0.6 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.3 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.0 | 0.2 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 0.5 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.0 | 0.3 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.0 | 0.4 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 0.2 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.0 | 0.1 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.0 | 0.1 | GO:0072557 | IPAF inflammasome complex(GO:0072557) |
| 0.0 | 0.3 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 0.4 | GO:0005942 | phosphatidylinositol 3-kinase complex(GO:0005942) |
| 0.0 | 0.2 | GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.0 | 0.6 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.2 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.0 | 1.5 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 0.1 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 0.0 | 1.5 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.2 | GO:0032300 | mismatch repair complex(GO:0032300) |
| 0.0 | 0.1 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.4 | GO:0002113 | interleukin-33 binding(GO:0002113) |
| 0.3 | 1.4 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.2 | 2.4 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.2 | 0.6 | GO:0019781 | NEDD8 activating enzyme activity(GO:0019781) |
| 0.2 | 1.0 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.2 | 0.7 | GO:0033765 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751) |
| 0.1 | 0.7 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.1 | 0.9 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
| 0.1 | 0.6 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.1 | 2.1 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.1 | 1.1 | GO:0046790 | virion binding(GO:0046790) |
| 0.1 | 1.3 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.1 | 0.8 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.1 | 1.1 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.1 | 0.3 | GO:0019115 | benzaldehyde dehydrogenase activity(GO:0019115) |
| 0.1 | 0.3 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.1 | 1.6 | GO:0008517 | folic acid transporter activity(GO:0008517) |
| 0.1 | 1.0 | GO:0045545 | syndecan binding(GO:0045545) |
| 0.1 | 0.3 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 0.1 | 3.1 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.1 | 2.5 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 0.3 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.1 | 0.5 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.1 | 0.3 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.1 | 0.2 | GO:0033149 | FFAT motif binding(GO:0033149) |
| 0.1 | 0.3 | GO:0042019 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.1 | 0.5 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 0.1 | 1.0 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.1 | 0.4 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.0 | 0.4 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.0 | 0.2 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.0 | 0.3 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.0 | 6.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.7 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.0 | 0.6 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.0 | 0.1 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.0 | 0.3 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.0 | 0.5 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.0 | 0.5 | GO:0089720 | caspase binding(GO:0089720) |
| 0.0 | 0.5 | GO:0043855 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.0 | 0.1 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 0.0 | 0.1 | GO:0004651 | polynucleotide 5'-phosphatase activity(GO:0004651) |
| 0.0 | 0.4 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
| 0.0 | 0.1 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.0 | 0.4 | GO:0046935 | 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935) |
| 0.0 | 0.7 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.0 | 0.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.0 | 0.2 | GO:0030377 | urokinase plasminogen activator receptor activity(GO:0030377) |
| 0.0 | 0.2 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.0 | 0.4 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.1 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.0 | 0.3 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.0 | 1.0 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.0 | 0.3 | GO:0003831 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831) |
| 0.0 | 0.8 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.0 | 0.2 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 0.2 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.0 | 0.2 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
| 0.0 | 0.5 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 1.1 | GO:0003755 | peptidyl-prolyl cis-trans isomerase activity(GO:0003755) |
| 0.0 | 0.0 | GO:0004397 | histidine ammonia-lyase activity(GO:0004397) |
| 0.0 | 0.1 | GO:0002114 | interleukin-33 receptor activity(GO:0002114) |
| 0.0 | 1.1 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.4 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.5 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.0 | 1.0 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.5 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 0.2 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.4 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.0 | 0.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 1.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.6 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.3 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 2.8 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 1.0 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 1.0 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 8.6 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.9 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.6 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.7 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.3 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.0 | 0.2 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 1.0 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.5 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.0 | 1.3 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.0 | 0.6 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 0.8 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 1.0 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.1 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.6 | PID MTOR 4PATHWAY | mTOR signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.1 | 0.9 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 1.4 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 1.1 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.0 | 0.7 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 0.0 | 1.5 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.7 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.0 | 0.5 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.0 | 1.2 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 2.8 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 0.7 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.7 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 0.4 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.0 | 2.1 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 0.5 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.3 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 1.2 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.6 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.0 | 0.3 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.0 | 0.3 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 1.0 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.4 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 1.0 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.3 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 0.3 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |