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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for BACH2
Z-value: 0.99
Motif logo
Transcription factors associated with BACH2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
BACH2
|
ENSG00000112182.10 | BTB domain and CNC homolog 2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BACH2 | hg19_v2_chr6_-_91006461_91006517 | 0.75 | 1.6e-04 | Click! |
Activity profile of BACH2 motif
Sorted Z-values of BACH2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of BACH2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 3.5 | GO:0018153 | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262) |
| 0.5 | 4.7 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.5 | 2.5 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 0.5 | 2.0 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.4 | 8.5 | GO:0051546 | keratinocyte migration(GO:0051546) |
| 0.4 | 1.1 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.3 | 2.2 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.3 | 1.5 | GO:0030807 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123) |
| 0.3 | 1.7 | GO:0098886 | modification of dendritic spine(GO:0098886) |
| 0.3 | 1.9 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.2 | 1.6 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 0.2 | 1.1 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.2 | 1.8 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.2 | 4.3 | GO:0016102 | retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102) |
| 0.2 | 2.6 | GO:0006477 | protein sulfation(GO:0006477) |
| 0.2 | 0.7 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.2 | 6.3 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.2 | 0.8 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.2 | 1.0 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.2 | 3.8 | GO:0060707 | trophoblast giant cell differentiation(GO:0060707) |
| 0.2 | 0.9 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 0.1 | 3.1 | GO:0016540 | protein autoprocessing(GO:0016540) |
| 0.1 | 2.2 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.1 | 1.2 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 0.7 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
| 0.1 | 1.0 | GO:1903575 | cornified envelope assembly(GO:1903575) |
| 0.1 | 3.6 | GO:0030502 | negative regulation of bone mineralization(GO:0030502) |
| 0.1 | 0.5 | GO:0032764 | negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.1 | 3.0 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.1 | 1.6 | GO:0007320 | insemination(GO:0007320) |
| 0.1 | 1.5 | GO:0001766 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 0.1 | 0.8 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.1 | 0.6 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.1 | 0.8 | GO:0071651 | positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) |
| 0.1 | 0.4 | GO:1903422 | negative regulation of synaptic vesicle recycling(GO:1903422) |
| 0.1 | 0.3 | GO:1903660 | negative regulation of complement-dependent cytotoxicity(GO:1903660) |
| 0.1 | 0.4 | GO:0021812 | neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812) |
| 0.1 | 0.9 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.1 | 0.6 | GO:0098881 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.1 | 0.4 | GO:1902728 | positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
| 0.1 | 3.8 | GO:0060512 | prostate gland morphogenesis(GO:0060512) |
| 0.1 | 0.9 | GO:0030091 | protein repair(GO:0030091) |
| 0.1 | 1.0 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.1 | 0.5 | GO:1905232 | cellular response to L-glutamate(GO:1905232) |
| 0.1 | 1.2 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.1 | 0.4 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 3.8 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.4 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.0 | 0.8 | GO:0097012 | cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012) |
| 0.0 | 0.1 | GO:1901656 | glycoside transport(GO:1901656) |
| 0.0 | 0.3 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 0.0 | 0.3 | GO:0044805 | late nucleophagy(GO:0044805) |
| 0.0 | 0.4 | GO:0032960 | regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962) |
| 0.0 | 0.8 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.0 | 0.9 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.0 | 0.2 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.0 | 1.5 | GO:0032461 | positive regulation of protein oligomerization(GO:0032461) |
| 0.0 | 0.3 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 0.0 | 0.6 | GO:0098902 | regulation of membrane depolarization during action potential(GO:0098902) |
| 0.0 | 0.2 | GO:0060742 | epithelial cell differentiation involved in prostate gland development(GO:0060742) |
| 0.0 | 0.9 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 0.1 | GO:1903028 | positive regulation of opsonization(GO:1903028) |
| 0.0 | 0.1 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.0 | 1.3 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 0.1 | GO:0033693 | neurofilament bundle assembly(GO:0033693) |
| 0.0 | 0.1 | GO:0048200 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.0 | 2.6 | GO:0030834 | regulation of actin filament depolymerization(GO:0030834) |
| 0.0 | 0.6 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.0 | 0.2 | GO:0042636 | negative regulation of hair cycle(GO:0042636) |
| 0.0 | 0.2 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.0 | 0.3 | GO:1903943 | regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944) |
| 0.0 | 0.7 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.0 | 0.0 | GO:0009609 | response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) |
| 0.0 | 2.5 | GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) |
| 0.0 | 0.7 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 0.8 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 1.6 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 0.3 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.0 | 0.4 | GO:0001765 | membrane raft assembly(GO:0001765) |
| 0.0 | 0.5 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
| 0.0 | 0.1 | GO:0010979 | regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) vitamin D catabolic process(GO:0042369) positive regulation of response to alcohol(GO:1901421) |
| 0.0 | 1.1 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.0 | 0.2 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.0 | 0.2 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.0 | 0.2 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.0 | 0.1 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.0 | 0.8 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.0 | 1.6 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.6 | GO:0034629 | cellular protein complex localization(GO:0034629) |
| 0.0 | 0.5 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
| 0.0 | 0.7 | GO:0006936 | muscle contraction(GO:0006936) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 2.6 | GO:0034515 | proteasome storage granule(GO:0034515) |
| 0.6 | 6.3 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.6 | 1.7 | GO:0097444 | spine apparatus(GO:0097444) |
| 0.2 | 0.9 | GO:0098592 | cytoplasmic side of apical plasma membrane(GO:0098592) |
| 0.2 | 1.0 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.2 | 3.6 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.2 | 1.0 | GO:0031673 | H zone(GO:0031673) |
| 0.1 | 0.6 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 0.1 | 0.8 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.1 | 0.4 | GO:0043257 | laminin-8 complex(GO:0043257) |
| 0.1 | 7.5 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 3.0 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 0.9 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.1 | 1.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 0.6 | GO:0005827 | polar microtubule(GO:0005827) |
| 0.1 | 1.6 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.1 | 0.5 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.1 | 2.2 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.8 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 0.7 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 0.8 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 0.3 | GO:0097513 | myosin II filament(GO:0097513) |
| 0.0 | 1.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 0.3 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.0 | 0.4 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.0 | 1.9 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 0.8 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 2.0 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 2.8 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 0.5 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 0.0 | 1.0 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.0 | 0.1 | GO:1902912 | pyruvate kinase complex(GO:1902912) |
| 0.0 | 0.4 | GO:0030130 | clathrin coat of trans-Golgi network vesicle(GO:0030130) |
| 0.0 | 2.5 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.0 | 0.7 | GO:0031105 | septin complex(GO:0031105) |
| 0.0 | 0.3 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.0 | 0.6 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 2.0 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 2.1 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 2.6 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 1.1 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 0.3 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 0.4 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.7 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
| 0.5 | 3.6 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.4 | 2.6 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.4 | 1.1 | GO:0070119 | ciliary neurotrophic factor binding(GO:0070119) |
| 0.3 | 1.2 | GO:0008260 | 3-oxoacid CoA-transferase activity(GO:0008260) |
| 0.2 | 0.8 | GO:1990175 | EH domain binding(GO:1990175) |
| 0.2 | 1.4 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.2 | 0.7 | GO:0004031 | aldehyde oxidase activity(GO:0004031) |
| 0.2 | 1.6 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.2 | 1.7 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.1 | 0.7 | GO:0003883 | CTP synthase activity(GO:0003883) |
| 0.1 | 2.6 | GO:0019841 | retinol binding(GO:0019841) |
| 0.1 | 0.9 | GO:0047493 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.1 | 0.9 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
| 0.1 | 3.0 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 5.1 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 2.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.6 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.1 | 2.0 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.1 | 1.5 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.1 | 0.9 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.1 | 1.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 0.3 | GO:0002134 | pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551) |
| 0.1 | 0.8 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.1 | 0.6 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.1 | 0.2 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.1 | 0.1 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 2.4 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 2.4 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.0 | 0.4 | GO:0000340 | RNA 7-methylguanosine cap binding(GO:0000340) |
| 0.0 | 2.2 | GO:0050431 | transforming growth factor beta binding(GO:0050431) |
| 0.0 | 12.4 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.4 | GO:0005143 | interleukin-12 receptor binding(GO:0005143) |
| 0.0 | 0.6 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.0 | 0.5 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.0 | 0.5 | GO:0008526 | phosphatidylcholine transporter activity(GO:0008525) phosphatidylinositol transporter activity(GO:0008526) |
| 0.0 | 0.8 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 3.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 1.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.1 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.0 | 0.8 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.0 | 0.4 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.6 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.0 | 0.4 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.0 | 0.4 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.0 | 0.6 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 1.5 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 9.7 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 5.0 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.7 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.0 | 3.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.5 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.0 | 1.1 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.0 | 0.2 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.0 | 0.2 | GO:0004565 | beta-galactosidase activity(GO:0004565) |
| 0.0 | 0.5 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 0.1 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.0 | 0.1 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.0 | 0.4 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.0 | 0.7 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.0 | 0.3 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
| 0.0 | 0.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 0.2 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 8.7 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 1.4 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.1 | 5.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 4.0 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 1.5 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 0.7 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 1.8 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.7 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 2.8 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 0.9 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 1.1 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.6 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.4 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.6 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.4 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.4 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 1.4 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 1.6 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.1 | 2.6 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 3.9 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 7.2 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.0 | 2.9 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.0 | 0.7 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.9 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 1.3 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 1.1 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 1.5 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 0.6 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.2 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.0 | 0.3 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.9 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.9 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.4 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 0.4 | REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C | Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C |
| 0.0 | 0.3 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |
| 0.0 | 0.3 | REACTOME RNA POL III CHAIN ELONGATION | Genes involved in RNA Polymerase III Chain Elongation |
| 0.0 | 0.8 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.4 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 0.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |