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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for BBX
Z-value: 1.09
Motif logo
Transcription factors associated with BBX
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
BBX
|
ENSG00000114439.14 | BBX high mobility group box domain containing |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BBX | hg19_v2_chr3_+_107241882_107241904 | -0.88 | 3.9e-07 | Click! |
Activity profile of BBX motif
Sorted Z-values of BBX motif
Network of associatons between targets according to the STRING database.
First level regulatory network of BBX
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 9.5 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.3 | 0.8 | GO:0002728 | negative regulation of natural killer cell cytokine production(GO:0002728) |
| 0.2 | 0.6 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.1 | 1.1 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 0.1 | 1.3 | GO:0015747 | urate transport(GO:0015747) |
| 0.1 | 0.4 | GO:1902161 | positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161) |
| 0.1 | 0.4 | GO:0031508 | pericentric heterochromatin assembly(GO:0031508) |
| 0.1 | 0.5 | GO:0070173 | regulation of enamel mineralization(GO:0070173) |
| 0.1 | 0.4 | GO:0033615 | mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615) |
| 0.1 | 0.3 | GO:0006480 | N-terminal protein amino acid methylation(GO:0006480) |
| 0.1 | 0.6 | GO:1903899 | lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899) |
| 0.1 | 0.9 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.1 | 0.5 | GO:0007619 | courtship behavior(GO:0007619) |
| 0.1 | 0.4 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
| 0.1 | 0.9 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.1 | 0.7 | GO:0050428 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 0.1 | 0.4 | GO:0009441 | glycolate metabolic process(GO:0009441) |
| 0.1 | 0.2 | GO:0070121 | pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121) |
| 0.0 | 0.5 | GO:0016998 | cell wall macromolecule catabolic process(GO:0016998) |
| 0.0 | 0.2 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.0 | 0.4 | GO:0000821 | regulation of arginine metabolic process(GO:0000821) |
| 0.0 | 0.5 | GO:0046951 | ketone body biosynthetic process(GO:0046951) |
| 0.0 | 0.4 | GO:0045078 | positive regulation of interferon-gamma biosynthetic process(GO:0045078) |
| 0.0 | 0.1 | GO:0036371 | protein localization to T-tubule(GO:0036371) |
| 0.0 | 0.4 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.0 | 0.4 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.0 | 0.9 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.3 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.0 | 0.2 | GO:0006216 | cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087) |
| 0.0 | 0.2 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.0 | 0.1 | GO:0010157 | response to chlorate(GO:0010157) |
| 0.0 | 0.1 | GO:0009257 | 10-formyltetrahydrofolate biosynthetic process(GO:0009257) |
| 0.0 | 0.6 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.2 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.0 | 1.2 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.0 | 0.2 | GO:0006108 | malate metabolic process(GO:0006108) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 9.5 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 1.1 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 0.4 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.1 | 0.5 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.0 | 0.5 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.3 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.0 | 0.2 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.6 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 1.3 | GO:0031526 | brush border membrane(GO:0031526) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 0.9 | GO:0019862 | IgA binding(GO:0019862) |
| 0.2 | 1.3 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 0.1 | 0.4 | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) |
| 0.1 | 0.5 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.1 | 0.4 | GO:0005260 | channel-conductance-controlling ATPase activity(GO:0005260) |
| 0.1 | 0.5 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.1 | 1.1 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.1 | 0.3 | GO:0071885 | N-terminal protein N-methyltransferase activity(GO:0071885) |
| 0.1 | 0.5 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.1 | 0.5 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 9.5 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.1 | 0.4 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.0 | 0.5 | GO:0003796 | lysozyme activity(GO:0003796) |
| 0.0 | 0.2 | GO:0047860 | diiodophenylpyruvate reductase activity(GO:0047860) |
| 0.0 | 0.2 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.0 | 0.7 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.4 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 0.2 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.0 | 0.9 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.2 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.0 | 0.6 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 0.2 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.0 | 0.4 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 0.0 | 0.4 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.0 | 0.6 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 0.2 | GO:0005549 | odorant binding(GO:0005549) |
| 0.0 | 0.1 | GO:0004329 | formate-tetrahydrofolate ligase activity(GO:0004329) |
| 0.0 | 0.3 | GO:0015125 | bile acid transmembrane transporter activity(GO:0015125) |
| 0.0 | 0.9 | GO:0004984 | olfactory receptor activity(GO:0004984) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.5 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 1.1 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.0 | 0.7 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 9.5 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 1.0 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 1.1 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 0.3 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.0 | 0.4 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.0 | 0.4 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.0 | 0.3 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 1.3 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |