ISMARA results: BCL6B

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for BCL6B

Z-value: 0.52

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Transcription factors associated with BCL6B

Gene Symbol	Gene ID	Gene Info
BCL6B Ensembl NCBI GeneCards UniProt	ENSG00000161940.6	BCL6B transcription repressor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
BCL6B	hg19_v2_chr17_+_6926339_6926377	-0.16	5.0e-01	Click!

Activity profile of BCL6B motif

Sorted Z-values of BCL6B motif

No targets for BCL6B

Network of associatons between targets according to the STRING database.

First level regulatory network of BCL6B

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0	0.8	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.6	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1	0.5	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.5	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.5	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.1	0.4	GO:1904235	regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.1	0.4	GO:2000691	regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.1	0.3	GO:0051714	positive regulation of cytolysis in other organism(GO:0051714)
0.1	0.3	GO:0031247	actin rod assembly(GO:0031247)

Showing 1 to 10 of 39 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.5	GO:0005916	fascia adherens(GO:0005916)
0.0	0.3	GO:0097342	ripoptosome(GO:0097342)
0.0	0.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.2	GO:0032002	interleukin-28 receptor complex(GO:0032002)
0.0	0.2	GO:0031905	early endosome lumen(GO:0031905)
0.0	0.2	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0	0.2	GO:0000788	nuclear nucleosome(GO:0000788)

Showing 1 to 8 of 8 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.9	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.2	0.5	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0	0.5	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1	0.3	GO:0008745	N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.1	0.3	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.3	GO:0046790	virion binding(GO:0046790)
0.0	0.3	GO:0045545	syndecan binding(GO:0045545)
0.0	0.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	0.2	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0	0.2	GO:0070728	leucine binding(GO:0070728)

Showing 1 to 10 of 22 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.4	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.

Showing 1 to 2 of 2 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Total log-likelihood	Term	Description
0.6	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.5	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.5	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.4	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway

Showing 1 to 8 of 8 entries

Results for BCL6B

Z-value: 0.52

Motif logo

Transcription factors associated with BCL6B

Activity-expression correlation:

Activity profile of BCL6B motif

Sorted Z-values of BCL6B motif

No targets for BCL6B

Network of associatons between targets according to the STRING database.

First level regulatory network of BCL6B

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: