ISMARA results: BPTF

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for BPTF

Z-value: 3.85

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Transcription factors associated with BPTF

Gene Symbol	Gene ID	Gene Info
BPTF Ensembl NCBI GeneCards UniProt	ENSG00000171634.12	bromodomain PHD finger transcription factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
BPTF	hg19_v2_chr17_+_65821636_65821641	0.18	4.4e-01	Click!

Activity profile of BPTF motif

Sorted Z-values of BPTF motif

No targets for BPTF

Network of associatons between targets according to the STRING database.

First level regulatory network of BPTF

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	13.9	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.9	11.5	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.4	10.4	GO:0090656	t-circle formation(GO:0090656)
1.0	10.3	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.3	9.6	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
1.3	9.3	GO:0007079	mitotic chromosome movement towards spindle pole(GO:0007079)
0.5	9.0	GO:0071420	cellular response to histamine(GO:0071420)
0.2	8.6	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.2	8.3	GO:0071431	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.5	7.5	GO:0019227	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)

Showing 1 to 10 of 663 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	12.7	GO:0042555	MCM complex(GO:0042555)
0.2	11.8	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	11.3	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.7	10.8	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.1	10.6	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.4	10.0	GO:0031616	spindle pole centrosome(GO:0031616)
0.1	8.9	GO:0005814	centriole(GO:0005814)
0.3	7.8	GO:1902711	GABA-A receptor complex(GO:1902711)
0.1	7.7	GO:0018995	host(GO:0018995) host cell(GO:0043657)
0.1	7.6	GO:0035580	specific granule lumen(GO:0035580)

Showing 1 to 10 of 299 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	10.8	GO:0003688	DNA replication origin binding(GO:0003688)
0.9	9.6	GO:0019237	centromeric DNA binding(GO:0019237)
0.4	9.2	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.1	9.1	GO:0019843	rRNA binding(GO:0019843)
0.8	9.0	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.2	8.0	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	7.8	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
1.9	7.5	GO:0008112	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.3	7.1	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1	6.9	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)

Showing 1 to 10 of 458 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	21.8	PID FANCONI PATHWAY	Fanconi anemia pathway
0.2	15.9	PID AURORA B PATHWAY	Aurora B signaling
0.3	14.4	PID ATR PATHWAY	ATR signaling pathway
0.4	10.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	9.4	PID BMP PATHWAY	BMP receptor signaling
0.1	9.1	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.1	8.9	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.1	8.3	PID PLK1 PATHWAY	PLK1 signaling events
0.1	7.8	PID AURORA A PATHWAY	Aurora A signaling
0.1	7.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network

Showing 1 to 10 of 71 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	20.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.2	15.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.2	13.2	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.6	12.7	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	11.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.2	11.3	REACTOME KINESINS	Genes involved in Kinesins
0.1	10.8	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4	10.0	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3	9.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.3	9.6	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)

Showing 1 to 10 of 146 entries

Results for BPTF

Z-value: 3.85

Motif logo

Transcription factors associated with BPTF

Activity-expression correlation:

Activity profile of BPTF motif

Sorted Z-values of BPTF motif

No targets for BPTF

Network of associatons between targets according to the STRING database.

First level regulatory network of BPTF

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: