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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for CAGUAGU
Z-value: 0.56
Motif logo
miRNA associated with seed CAGUAGU
| Name | miRBASE accession |
|---|---|
|
hsa-miR-199a-3p
|
MIMAT0000232 |
|
hsa-miR-199b-3p
|
MIMAT0004563 |
|
hsa-miR-3129-5p
|
MIMAT0014992 |
Activity profile of CAGUAGU motif
Sorted Z-values of CAGUAGU motif
Network of associatons between targets according to the STRING database.
First level regulatory network of CAGUAGU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:1903045 | neural crest cell migration involved in sympathetic nervous system development(GO:1903045) |
| 0.1 | 0.3 | GO:0050720 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) interleukin-1 beta biosynthetic process(GO:0050720) |
| 0.1 | 0.3 | GO:0034085 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930) |
| 0.1 | 0.5 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 0.1 | 0.5 | GO:0060005 | vestibular reflex(GO:0060005) |
| 0.1 | 0.2 | GO:0048007 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.1 | 0.5 | GO:0072674 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 0.1 | 0.3 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.1 | 0.4 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.1 | 0.5 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.1 | 0.3 | GO:0035801 | adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) |
| 0.1 | 0.2 | GO:1904237 | regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237) |
| 0.1 | 0.2 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 0.0 | 0.8 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.0 | 0.1 | GO:2000681 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 0.0 | 0.1 | GO:0021718 | superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
| 0.0 | 0.3 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 0.0 | 0.4 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.0 | 0.3 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.0 | 0.2 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 0.0 | 0.2 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 0.0 | 0.6 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.0 | 0.2 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.0 | 0.3 | GO:1903826 | arginine transmembrane transport(GO:1903826) |
| 0.0 | 0.2 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 0.0 | 0.3 | GO:0019065 | receptor-mediated endocytosis of virus by host cell(GO:0019065) modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) positive regulation of dopamine receptor signaling pathway(GO:0060161) endocytosis involved in viral entry into host cell(GO:0075509) |
| 0.0 | 0.2 | GO:0030336 | negative regulation of cell migration(GO:0030336) |
| 0.0 | 0.1 | GO:1902309 | regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.0 | 0.1 | GO:0045875 | negative regulation of sister chromatid cohesion(GO:0045875) |
| 0.0 | 0.2 | GO:0097368 | establishment of Sertoli cell barrier(GO:0097368) |
| 0.0 | 0.2 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 0.0 | 0.5 | GO:0010668 | ectodermal cell differentiation(GO:0010668) |
| 0.0 | 0.1 | GO:0032489 | aminophospholipid transport(GO:0015917) regulation of Cdc42 protein signal transduction(GO:0032489) regulation of high-density lipoprotein particle assembly(GO:0090107) |
| 0.0 | 0.2 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.0 | 0.2 | GO:0035977 | protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) |
| 0.0 | 0.2 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.0 | 0.2 | GO:0032237 | activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341) |
| 0.0 | 0.3 | GO:0061303 | cornea development in camera-type eye(GO:0061303) |
| 0.0 | 0.2 | GO:0021999 | neural plate anterior/posterior regionalization(GO:0021999) |
| 0.0 | 0.2 | GO:0000710 | meiotic mismatch repair(GO:0000710) |
| 0.0 | 0.3 | GO:0060449 | bud elongation involved in lung branching(GO:0060449) |
| 0.0 | 0.2 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.0 | 0.4 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.0 | 0.1 | GO:2000568 | memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568) |
| 0.0 | 0.1 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 0.0 | 0.3 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.0 | 0.1 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.0 | 0.1 | GO:0060437 | lung growth(GO:0060437) |
| 0.0 | 0.2 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.0 | 0.0 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 0.0 | 0.3 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.0 | 0.1 | GO:0034721 | histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721) |
| 0.0 | 0.1 | GO:0007621 | negative regulation of female receptivity(GO:0007621) |
| 0.0 | 0.1 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.0 | 0.2 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.0 | 0.6 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.0 | GO:0003032 | detection of oxygen(GO:0003032) |
| 0.0 | 0.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0034676 | integrin alpha6-beta4 complex(GO:0034676) |
| 0.1 | 0.3 | GO:0005595 | collagen type XII trimer(GO:0005595) |
| 0.1 | 0.3 | GO:0034686 | integrin alphav-beta8 complex(GO:0034686) |
| 0.1 | 0.3 | GO:0035189 | Rb-E2F complex(GO:0035189) |
| 0.1 | 0.5 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
| 0.1 | 0.3 | GO:0071149 | TEAD-2-YAP complex(GO:0071149) |
| 0.1 | 0.9 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 0.2 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 0.0 | 0.1 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.0 | 0.4 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.0 | 0.2 | GO:0032301 | MutSalpha complex(GO:0032301) |
| 0.0 | 0.1 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.0 | 0.2 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.0 | 0.1 | GO:0075341 | host cell PML body(GO:0075341) |
| 0.0 | 0.4 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.0 | 0.3 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 0.1 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 0.3 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 0.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.0 | 0.2 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.0 | 0.2 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 0.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.3 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.1 | 0.3 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.1 | 0.3 | GO:0061676 | importin-alpha family protein binding(GO:0061676) |
| 0.0 | 0.1 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
| 0.0 | 0.3 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.0 | 0.2 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.0 | 0.5 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.0 | 0.3 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
| 0.0 | 0.1 | GO:0090556 | apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556) |
| 0.0 | 0.2 | GO:0032143 | single thymine insertion binding(GO:0032143) |
| 0.0 | 0.1 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.0 | 0.4 | GO:0031386 | protein tag(GO:0031386) |
| 0.0 | 0.3 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.0 | 0.3 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.0 | 0.2 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.0 | 0.8 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.0 | 0.7 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.5 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.0 | 0.2 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.0 | 0.1 | GO:0008426 | protein kinase C inhibitor activity(GO:0008426) |
| 0.0 | 0.3 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 0.4 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.0 | 0.1 | GO:0023030 | MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030) |
| 0.0 | 0.3 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.0 | 0.1 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.0 | 0.2 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
| 0.0 | 0.5 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 0.1 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 0.0 | 0.2 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 0.2 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.5 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.5 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 0.8 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 0.8 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.5 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 0.3 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.0 | 1.2 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 0.3 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |