ISMARA results: CCCUGAG

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CCCUGAG

Z-value: 2.13

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miRNA associated with seed CCCUGAG

Name	miRBASE accession
hsa-miR-125a-5p miRBase	MIMAT0000443
hsa-miR-125b-5p miRBase	MIMAT0000423
hsa-miR-4319 miRBase	MIMAT0016870

Activity profile of CCCUGAG motif

Sorted Z-values of CCCUGAG motif

No targets for CCCUGAG

Network of associatons between targets according to the STRING database.

First level regulatory network of CCCUGAG

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.7	GO:1902162	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.8	2.4	GO:0034147	regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.0	2.4	GO:0007212	dopamine receptor signaling pathway(GO:0007212)
0.3	2.2	GO:1904925	negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0	2.2	GO:0050919	negative chemotaxis(GO:0050919)
0.3	2.0	GO:0060005	vestibular reflex(GO:0060005)
0.2	1.7	GO:0035897	proteolysis in other organism(GO:0035897)
0.1	1.7	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	1.7	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.0	1.7	GO:0031532	actin cytoskeleton reorganization(GO:0031532)

Showing 1 to 10 of 170 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	2.0	GO:0016605	PML body(GO:0016605)
0.1	1.6	GO:0042588	zymogen granule(GO:0042588)
0.0	1.6	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	1.5	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
0.3	1.3	GO:0060187	cell pole(GO:0060187)
0.0	1.3	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.1	1.2	GO:0097225	sperm midpiece(GO:0097225)
0.0	1.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	1.2	GO:0035580	specific granule lumen(GO:0035580)

Showing 1 to 10 of 53 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	8.4	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	4.1	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	3.4	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	3.4	GO:0001158	enhancer sequence-specific DNA binding(GO:0001158)
0.1	2.7	GO:0031489	myosin V binding(GO:0031489)
0.1	2.4	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.1	2.4	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.1	2.3	GO:0051400	BH domain binding(GO:0051400)
0.1	2.3	GO:0038191	neuropilin binding(GO:0038191)
0.2	2.2	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)

Showing 1 to 10 of 117 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.5	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	3.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	3.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	2.9	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	2.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.1	2.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	2.0	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	2.0	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.0	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	1.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II

Showing 1 to 10 of 29 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.9	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	2.3	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.0	1.7	REACTOME POTASSIUM CHANNELS	Genes involved in Potassium Channels
0.1	1.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	1.5	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0	1.3	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	1.3	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	1.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	1.2	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.0	1.1	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis

Showing 1 to 10 of 34 entries

Results for CCCUGAG

Z-value: 2.13

Motif logo

miRNA associated with seed CCCUGAG

Activity profile of CCCUGAG motif

Sorted Z-values of CCCUGAG motif

No targets for CCCUGAG

Network of associatons between targets according to the STRING database.

First level regulatory network of CCCUGAG

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: