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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CCCUGAG

Z-value: 2.13

Motif logo

miRNA associated with seed CCCUGAG

NamemiRBASE accession
MIMAT0000443
MIMAT0000423
MIMAT0016870

Activity profile of CCCUGAG motif

Sorted Z-values of CCCUGAG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CCCUGAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0034147 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.5 1.5 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.5 0.5 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.4 1.3 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 1.2 GO:0042938 dipeptide transport(GO:0042938)
0.4 2.7 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.3 2.0 GO:0060005 vestibular reflex(GO:0060005)
0.3 1.6 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.3 0.6 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.3 2.2 GO:1904925 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.3 1.5 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.3 1.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.3 0.8 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.3 1.6 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.3 1.0 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.3 1.0 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 1.0 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.2 1.2 GO:1902534 single-organism membrane invagination(GO:1902534)
0.2 1.4 GO:0051697 protein delipidation(GO:0051697)
0.2 0.6 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.2 0.2 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.2 0.6 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.2 0.6 GO:0061386 closure of optic fissure(GO:0061386)
0.2 0.7 GO:0042351 'de novo' GDP-L-fucose biosynthetic process(GO:0042351)
0.2 1.1 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 0.9 GO:2000051 Wnt receptor catabolic process(GO:0038018) negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 0.5 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.2 0.5 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.2 0.3 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.2 1.7 GO:0035897 proteolysis in other organism(GO:0035897)
0.2 0.5 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.6 GO:1990927 vesicle-mediated cholesterol transport(GO:0090119) short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 1.6 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 0.4 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.1 0.5 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.4 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.1 0.6 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.5 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.6 GO:0061528 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.4 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 1.0 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.8 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.7 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.5 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 1.3 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.7 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.1 0.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 0.4 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.1 0.3 GO:1904747 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1 0.3 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.3 GO:0070904 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.5 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.5 GO:1901490 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) regulation of lymphangiogenesis(GO:1901490)
0.1 0.3 GO:0018277 protein deamination(GO:0018277)
0.1 0.6 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 0.7 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 0.4 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.3 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.9 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.6 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.3 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.8 GO:0086027 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.1 0.3 GO:0021784 postganglionic parasympathetic fiber development(GO:0021784)
0.1 0.9 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 1.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 1.4 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 0.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.5 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.6 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.4 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.6 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.3 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 1.7 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.6 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.6 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 1.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.1 GO:2000979 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) optic placode formation involved in camera-type eye formation(GO:0046619) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 2.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 0.7 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 1.0 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.6 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 1.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 1.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 2.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 1.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.5 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.7 GO:0003334 keratinocyte development(GO:0003334)
0.0 1.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 1.0 GO:0050779 RNA destabilization(GO:0050779)
0.0 0.9 GO:0030220 platelet formation(GO:0030220)
0.0 0.0 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.9 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.6 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164) positive regulation of opsonization(GO:1903028)
0.0 0.3 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0 0.3 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
0.0 1.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:1901383 negative regulation of chorionic trophoblast cell proliferation(GO:1901383)
0.0 0.2 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.3 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.4 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.9 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.0 0.6 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0001767 establishment of lymphocyte polarity(GO:0001767)
0.0 0.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.0 0.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.3 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.0 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.6 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.9 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.0 0.3 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0 0.7 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.1 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.4 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.5 GO:0007507 heart development(GO:0007507)
0.0 1.5 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 1.6 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.5 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.0 0.3 GO:0045686 negative regulation of glial cell differentiation(GO:0045686)
0.0 0.0 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 1.7 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.5 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0051532 regulation of NFAT protein import into nucleus(GO:0051532) positive regulation of NFAT protein import into nucleus(GO:0051533)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0060187 cell pole(GO:0060187)
0.3 0.9 GO:0098855 HCN channel complex(GO:0098855)
0.2 1.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.2 2.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.5 GO:0097196 Shu complex(GO:0097196)
0.1 0.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.6 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 1.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.5 GO:0031251 PAN complex(GO:0031251)
0.1 0.6 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 0.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.6 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.6 GO:0042588 zymogen granule(GO:0042588)
0.1 1.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.1 0.3 GO:0016938 kinesin I complex(GO:0016938)
0.1 0.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 1.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.6 GO:0032009 early phagosome(GO:0032009)
0.0 0.9 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0071203 WASH complex(GO:0071203)
0.0 0.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 1.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 1.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.0 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0005925 focal adhesion(GO:0005925)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.2 GO:0035580 specific granule lumen(GO:0035580)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 2.0 GO:0016605 PML body(GO:0016605)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.2 0.7 GO:0050577 GDP-4-dehydro-D-rhamnose reductase activity(GO:0042356) GDP-L-fucose synthase activity(GO:0050577)
0.2 2.2 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 1.2 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.2 0.7 GO:0070984 SET domain binding(GO:0070984)
0.2 0.6 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.2 0.9 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 1.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 1.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.4 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.6 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 1.7 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.5 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.6 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 1.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 2.3 GO:0051400 BH domain binding(GO:0051400)
0.1 0.5 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.5 GO:0010736 serum response element binding(GO:0010736)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.3 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.6 GO:0098821 BMP receptor activity(GO:0098821)
0.1 0.9 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.4 GO:0017089 glycolipid transporter activity(GO:0017089)
0.1 2.7 GO:0031489 myosin V binding(GO:0031489)
0.1 0.4 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1 0.3 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 1.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 1.3 GO:0048185 activin binding(GO:0048185)
0.1 0.3 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.9 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 2.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 2.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.3 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 2.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.9 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 1.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 1.3 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.0 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 1.1 GO:0035198 miRNA binding(GO:0035198)
0.0 1.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 1.0 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 1.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.6 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.9 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.6 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.3 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.6 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.3 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.6 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 3.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.4 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 3.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.4 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 1.0 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.2 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 4.1 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.6 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.6 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.0 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.5 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 1.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.3 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 8.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.2 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.5 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0030971 receptor tyrosine kinase binding(GO:0030971)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.6 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 2.5 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 6.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 2.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.9 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 2.0 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 3.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.9 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 1.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.6 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.0 1.5 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.5 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 1.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME NEUROTRANSMITTER RELEASE CYCLE Genes involved in Neurotransmitter Release Cycle
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets