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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CEBPG

Z-value: 1.99

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Transcription factors associated with CEBPG

Gene Symbol Gene ID Gene Info
ENSG00000153879.4 CCAAT enhancer binding protein gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPGhg19_v2_chr19_+_33865218_33865254-0.651.8e-03Click!

Activity profile of CEBPG motif

Sorted Z-values of CEBPG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 11.8 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.8 3.3 GO:1990637 response to prolactin(GO:1990637)
0.7 2.2 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.5 2.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.5 1.5 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.5 3.9 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.4 1.3 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.4 7.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 0.7 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.3 12.2 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.3 2.0 GO:0008218 bioluminescence(GO:0008218)
0.3 1.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3 0.8 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.2 6.6 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.2 1.6 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713) cellular response to UV-C(GO:0071494)
0.2 1.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 0.7 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.2 0.6 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 1.6 GO:0032782 bile acid secretion(GO:0032782)
0.1 1.8 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.6 GO:0051546 keratinocyte migration(GO:0051546)
0.1 0.2 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 0.6 GO:0045345 positive regulation of MHC class I biosynthetic process(GO:0045345)
0.1 0.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 5.5 GO:0006953 acute-phase response(GO:0006953)
0.1 1.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 2.4 GO:0006825 copper ion transport(GO:0006825)
0.1 3.2 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 0.3 GO:0030185 nitric oxide transport(GO:0030185)
0.1 1.2 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 2.2 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.6 GO:0015866 ADP transport(GO:0015866)
0.0 0.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.6 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.0 1.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.4 GO:0046415 urate metabolic process(GO:0046415)
0.0 2.2 GO:0002292 T cell differentiation involved in immune response(GO:0002292)
0.0 0.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.5 GO:0098743 cell aggregation(GO:0098743)
0.0 0.3 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0010841 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.9 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.3 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.6 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 1.8 GO:0031638 zymogen activation(GO:0031638)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 1.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.8 GO:0097179 protease inhibitor complex(GO:0097179)
0.4 2.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 16.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 1.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 0.6 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 14.6 GO:0035580 specific granule lumen(GO:0035580)
0.1 1.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 2.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.5 GO:0005577 fibrinogen complex(GO:0005577)
0.1 13.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.7 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.6 GO:0043203 axon hillock(GO:0043203)
0.0 0.5 GO:0071437 invadopodium(GO:0071437)
0.0 3.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.0 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.3 1.0 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.3 16.6 GO:0042056 chemoattractant activity(GO:0042056)
0.3 0.8 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.3 3.8 GO:0089720 caspase binding(GO:0089720)
0.2 1.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.2 2.0 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 0.6 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 4.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 6.8 GO:0001848 complement binding(GO:0001848)
0.2 1.9 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 1.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.7 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.5 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.4 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.1 0.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.2 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.1 12.2 GO:0002020 protease binding(GO:0002020)
0.1 2.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.7 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 10.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 2.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.0 6.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 1.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 2.5 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 10.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 7.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 6.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.0 ST STAT3 PATHWAY STAT3 Pathway
0.1 2.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.5 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.3 10.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.5 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 3.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 1.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade