avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
CENPB
|
ENSG00000125817.7 | centromere protein B |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
CENPB | hg19_v2_chr20_-_3767324_3767443 | 0.76 | 9.8e-05 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 2.5 | GO:0042369 | vitamin D catabolic process(GO:0042369) |
0.6 | 2.3 | GO:1902361 | mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361) |
0.5 | 1.6 | GO:0006267 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
0.4 | 1.3 | GO:2000338 | interleukin-15 production(GO:0032618) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) positive regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000340) |
0.4 | 1.2 | GO:2000196 | positive regulation of female gonad development(GO:2000196) |
0.3 | 0.9 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
0.3 | 1.2 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
0.3 | 1.8 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
0.2 | 1.7 | GO:0015798 | myo-inositol transport(GO:0015798) |
0.2 | 0.7 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
0.2 | 0.7 | GO:1990051 | activation of protein kinase C activity(GO:1990051) |
0.2 | 1.7 | GO:0002353 | regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353) |
0.2 | 5.7 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
0.2 | 2.3 | GO:0046146 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
0.2 | 0.6 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
0.2 | 0.6 | GO:1905069 | allantois development(GO:1905069) |
0.2 | 1.1 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
0.2 | 1.8 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
0.2 | 2.4 | GO:0007144 | female meiosis I(GO:0007144) |
0.2 | 2.3 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
0.1 | 1.8 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.1 | 3.7 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
0.1 | 0.4 | GO:0034552 | respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032) |
0.1 | 0.4 | GO:0098923 | retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545) |
0.1 | 0.6 | GO:1903615 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
0.1 | 0.5 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
0.1 | 1.7 | GO:0051151 | negative regulation of smooth muscle cell differentiation(GO:0051151) |
0.1 | 7.3 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
0.1 | 0.4 | GO:0045829 | negative regulation of isotype switching(GO:0045829) |
0.1 | 0.5 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.1 | 1.9 | GO:0007220 | Notch receptor processing(GO:0007220) |
0.1 | 0.2 | GO:1904924 | negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924) |
0.1 | 0.8 | GO:0001826 | inner cell mass cell differentiation(GO:0001826) |
0.1 | 3.0 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
0.1 | 1.6 | GO:0007379 | segment specification(GO:0007379) |
0.1 | 0.3 | GO:0061760 | antifungal innate immune response(GO:0061760) |
0.1 | 0.5 | GO:1903679 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
0.1 | 1.2 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
0.1 | 1.6 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
0.1 | 10.1 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.1 | 1.8 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
0.1 | 2.5 | GO:0014002 | astrocyte development(GO:0014002) |
0.1 | 0.9 | GO:0002862 | negative regulation of inflammatory response to antigenic stimulus(GO:0002862) |
0.1 | 1.8 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
0.0 | 2.1 | GO:0070536 | protein K63-linked deubiquitination(GO:0070536) |
0.0 | 0.8 | GO:0042424 | catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424) |
0.0 | 0.7 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
0.0 | 0.8 | GO:0046777 | protein autophosphorylation(GO:0046777) |
0.0 | 1.0 | GO:0036109 | alpha-linolenic acid metabolic process(GO:0036109) linoleic acid metabolic process(GO:0043651) |
0.0 | 0.6 | GO:0001682 | tRNA 5'-leader removal(GO:0001682) |
0.0 | 0.2 | GO:0046600 | negative regulation of centriole replication(GO:0046600) |
0.0 | 1.1 | GO:0042391 | regulation of membrane potential(GO:0042391) |
0.0 | 0.2 | GO:0019064 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
0.0 | 0.2 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.0 | 0.6 | GO:0006103 | 2-oxoglutarate metabolic process(GO:0006103) |
0.0 | 1.9 | GO:0007193 | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193) |
0.0 | 1.9 | GO:0051865 | protein autoubiquitination(GO:0051865) |
0.0 | 1.4 | GO:0000266 | mitochondrial fission(GO:0000266) |
0.0 | 0.3 | GO:0006782 | protoporphyrinogen IX biosynthetic process(GO:0006782) |
0.0 | 0.4 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
0.0 | 0.4 | GO:0006012 | galactose metabolic process(GO:0006012) |
0.0 | 2.6 | GO:0014902 | myotube differentiation(GO:0014902) |
0.0 | 0.1 | GO:0021849 | neuroblast division in subventricular zone(GO:0021849) |
0.0 | 0.1 | GO:1990009 | retinal cell apoptotic process(GO:1990009) |
0.0 | 0.7 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
0.0 | 1.6 | GO:0021510 | spinal cord development(GO:0021510) |
0.0 | 0.0 | GO:0071629 | cytoplasm-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071629) |
0.0 | 0.6 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.0 | 0.5 | GO:0055090 | acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) |
0.0 | 0.3 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0005656 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
0.3 | 1.2 | GO:0002081 | outer acrosomal membrane(GO:0002081) |
0.3 | 1.8 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.3 | 1.6 | GO:0071817 | MMXD complex(GO:0071817) |
0.2 | 1.1 | GO:0031510 | SUMO activating enzyme complex(GO:0031510) |
0.2 | 1.9 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.1 | 0.5 | GO:0045293 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
0.1 | 9.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.1 | 1.9 | GO:0034709 | methylosome(GO:0034709) |
0.1 | 1.5 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
0.1 | 1.8 | GO:0042555 | MCM complex(GO:0042555) |
0.1 | 0.6 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.1 | 1.8 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
0.1 | 2.8 | GO:0031304 | intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305) |
0.1 | 3.1 | GO:0034451 | centriolar satellite(GO:0034451) |
0.1 | 1.6 | GO:0035102 | PRC1 complex(GO:0035102) |
0.1 | 0.8 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
0.1 | 0.9 | GO:0019774 | proteasome core complex, beta-subunit complex(GO:0019774) |
0.0 | 0.4 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
0.0 | 0.7 | GO:0097225 | sperm midpiece(GO:0097225) |
0.0 | 1.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.1 | GO:0014802 | terminal cisterna(GO:0014802) |
0.0 | 0.5 | GO:0060077 | inhibitory synapse(GO:0060077) |
0.0 | 1.8 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
0.0 | 2.5 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.4 | GO:0032433 | filopodium tip(GO:0032433) |
0.0 | 1.7 | GO:0045178 | basal part of cell(GO:0045178) |
0.0 | 0.3 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
0.0 | 0.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.0 | 3.6 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.2 | 3.7 | GO:0016731 | ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731) |
0.6 | 1.7 | GO:0005365 | myo-inositol transmembrane transporter activity(GO:0005365) |
0.5 | 2.5 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
0.4 | 1.1 | GO:0019948 | SUMO activating enzyme activity(GO:0019948) |
0.3 | 1.0 | GO:0045485 | omega-6 fatty acid desaturase activity(GO:0045485) |
0.3 | 2.3 | GO:0050833 | pyruvate transmembrane transporter activity(GO:0050833) |
0.3 | 1.3 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
0.2 | 0.7 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
0.2 | 0.6 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
0.2 | 1.6 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
0.2 | 1.8 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
0.2 | 0.6 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
0.2 | 0.8 | GO:0070579 | methylcytosine dioxygenase activity(GO:0070579) |
0.2 | 0.5 | GO:0001147 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
0.2 | 1.1 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
0.2 | 0.7 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
0.2 | 7.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.2 | 0.5 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
0.1 | 0.4 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
0.1 | 10.1 | GO:0019843 | rRNA binding(GO:0019843) |
0.1 | 1.9 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
0.1 | 2.1 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
0.1 | 1.2 | GO:0032190 | acrosin binding(GO:0032190) |
0.1 | 0.5 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.1 | 1.0 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.1 | 0.8 | GO:0016206 | catechol O-methyltransferase activity(GO:0016206) |
0.1 | 0.7 | GO:0004515 | nicotinate-nucleotide adenylyltransferase activity(GO:0004515) |
0.1 | 0.3 | GO:0003870 | 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749) |
0.1 | 1.6 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
0.1 | 1.8 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
0.1 | 1.7 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
0.1 | 0.6 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
0.1 | 1.2 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
0.0 | 2.3 | GO:0004033 | aldo-keto reductase (NADP) activity(GO:0004033) |
0.0 | 1.8 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 0.6 | GO:0070700 | BMP receptor binding(GO:0070700) |
0.0 | 0.6 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.0 | 0.9 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
0.0 | 0.4 | GO:0004300 | enoyl-CoA hydratase activity(GO:0004300) |
0.0 | 0.5 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
0.0 | 1.2 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
0.0 | 2.1 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
0.0 | 1.1 | GO:0030552 | cAMP binding(GO:0030552) |
0.0 | 2.6 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
0.0 | 0.4 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
0.0 | 0.4 | GO:0042043 | neurexin family protein binding(GO:0042043) |
0.0 | 0.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.2 | GO:0032027 | myosin light chain binding(GO:0032027) |
0.0 | 0.1 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
0.0 | 1.9 | GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors(GO:0016614) |
0.0 | 0.6 | GO:0042287 | MHC protein binding(GO:0042287) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 7.3 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
0.1 | 1.9 | PID S1P S1P4 PATHWAY | S1P4 pathway |
0.1 | 1.2 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
0.1 | 2.6 | ST GA12 PATHWAY | G alpha 12 Pathway |
0.1 | 1.9 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
0.0 | 4.1 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
0.0 | 1.3 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
0.0 | 0.6 | PID ALK2 PATHWAY | ALK2 signaling events |
0.0 | 1.8 | PID ATR PATHWAY | ATR signaling pathway |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.4 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
0.1 | 7.3 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
0.1 | 9.4 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
0.1 | 1.9 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
0.1 | 2.4 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.1 | 1.7 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
0.1 | 1.2 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.1 | 2.5 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
0.0 | 1.9 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
0.0 | 0.2 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
0.0 | 1.0 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
0.0 | 1.3 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
0.0 | 1.1 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
0.0 | 1.8 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
0.0 | 0.5 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.4 | REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.0 | 0.6 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
0.0 | 0.6 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
0.0 | 1.1 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
0.0 | 0.9 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
0.0 | 1.7 | REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS | Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds |
0.0 | 0.5 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.7 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |