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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for CREB1
Z-value: 3.44
Motif logo
Transcription factors associated with CREB1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
CREB1
|
ENSG00000118260.10 | cAMP responsive element binding protein 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CREB1 | hg19_v2_chr2_+_208394658_208394692 | 0.70 | 6.1e-04 | Click! |
Activity profile of CREB1 motif
Sorted Z-values of CREB1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of CREB1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 5.2 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 1.2 | 3.5 | GO:0034727 | lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) |
| 1.0 | 2.9 | GO:1901340 | negative regulation of store-operated calcium channel activity(GO:1901340) |
| 0.9 | 3.8 | GO:0009138 | pyrimidine nucleoside diphosphate metabolic process(GO:0009138) |
| 0.7 | 6.4 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.6 | 5.9 | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
| 0.6 | 1.7 | GO:0098972 | dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972) |
| 0.6 | 2.2 | GO:0033140 | negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140) |
| 0.5 | 2.7 | GO:0070901 | mitochondrial tRNA methylation(GO:0070901) |
| 0.5 | 1.5 | GO:1903988 | spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988) |
| 0.5 | 1.9 | GO:0031081 | nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664) |
| 0.5 | 2.4 | GO:0060830 | ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) |
| 0.5 | 1.9 | GO:1901491 | negative regulation of lymphangiogenesis(GO:1901491) |
| 0.5 | 1.9 | GO:0006272 | leading strand elongation(GO:0006272) |
| 0.4 | 7.2 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.4 | 2.5 | GO:0039689 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 0.4 | 1.1 | GO:0070681 | glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681) |
| 0.4 | 1.1 | GO:0006433 | glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433) |
| 0.3 | 2.0 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.3 | 1.0 | GO:0006481 | C-terminal protein methylation(GO:0006481) |
| 0.3 | 2.6 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197) |
| 0.3 | 1.3 | GO:0009386 | translational attenuation(GO:0009386) |
| 0.3 | 1.2 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.3 | 8.4 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.3 | 2.8 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.3 | 1.9 | GO:0030047 | actin modification(GO:0030047) |
| 0.3 | 1.2 | GO:0098838 | reduced folate transmembrane transport(GO:0098838) |
| 0.3 | 2.2 | GO:2000348 | regulation of CD40 signaling pathway(GO:2000348) |
| 0.3 | 0.8 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) |
| 0.3 | 1.6 | GO:0045903 | positive regulation of translational fidelity(GO:0045903) |
| 0.3 | 3.2 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.3 | 2.1 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
| 0.3 | 3.9 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.3 | 2.3 | GO:0042797 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.3 | 2.0 | GO:0060702 | negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) |
| 0.2 | 0.7 | GO:0071586 | CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120) |
| 0.2 | 1.6 | GO:2000048 | negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048) |
| 0.2 | 3.6 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.2 | 0.9 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
| 0.2 | 0.8 | GO:0005997 | xylulose metabolic process(GO:0005997) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 0.2 | 0.9 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 0.2 | 0.7 | GO:0007231 | osmosensory signaling pathway(GO:0007231) |
| 0.2 | 1.3 | GO:0048254 | snoRNA localization(GO:0048254) |
| 0.2 | 0.8 | GO:0034184 | positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) |
| 0.2 | 1.4 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.2 | 1.4 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.1 | 2.1 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.1 | 1.0 | GO:0048539 | bone marrow development(GO:0048539) |
| 0.1 | 1.1 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.1 | 0.7 | GO:0043328 | protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
| 0.1 | 0.5 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.1 | 4.6 | GO:0006625 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.1 | 1.0 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
| 0.1 | 2.6 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.1 | 1.6 | GO:0032364 | oxygen homeostasis(GO:0032364) |
| 0.1 | 2.7 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
| 0.1 | 0.6 | GO:0045829 | negative regulation of isotype switching(GO:0045829) |
| 0.1 | 2.3 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.1 | 2.9 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.1 | 1.3 | GO:0034465 | response to carbon monoxide(GO:0034465) |
| 0.1 | 2.0 | GO:0006296 | nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) |
| 0.1 | 0.3 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 0.1 | 2.7 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 0.1 | 5.1 | GO:0033120 | positive regulation of RNA splicing(GO:0033120) |
| 0.1 | 1.1 | GO:2001140 | regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140) |
| 0.1 | 0.8 | GO:0070987 | error-free translesion synthesis(GO:0070987) |
| 0.1 | 2.7 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 0.3 | GO:0072717 | cellular response to actinomycin D(GO:0072717) |
| 0.1 | 5.4 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 0.2 | GO:0006667 | sphinganine metabolic process(GO:0006667) |
| 0.1 | 1.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 0.2 | GO:0036451 | cap mRNA methylation(GO:0036451) |
| 0.1 | 0.5 | GO:0031536 | positive regulation of exit from mitosis(GO:0031536) |
| 0.1 | 0.2 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
| 0.1 | 5.5 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.1 | 0.3 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.1 | 1.8 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.1 | 2.4 | GO:0000460 | maturation of 5.8S rRNA(GO:0000460) |
| 0.1 | 1.0 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 3.7 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.1 | 4.0 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.1 | 1.3 | GO:2001241 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241) |
| 0.1 | 0.4 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.1 | 0.6 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.7 | GO:0021960 | anterior commissure morphogenesis(GO:0021960) |
| 0.0 | 1.6 | GO:0045880 | positive regulation of smoothened signaling pathway(GO:0045880) |
| 0.0 | 1.8 | GO:0030261 | chromosome condensation(GO:0030261) |
| 0.0 | 0.9 | GO:0034134 | toll-like receptor 2 signaling pathway(GO:0034134) |
| 0.0 | 0.8 | GO:0051775 | response to redox state(GO:0051775) |
| 0.0 | 0.8 | GO:0050942 | positive regulation of pigment cell differentiation(GO:0050942) |
| 0.0 | 0.2 | GO:0000960 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
| 0.0 | 0.9 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.0 | 0.1 | GO:0035522 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.0 | 1.1 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
| 0.0 | 1.3 | GO:0006363 | termination of RNA polymerase I transcription(GO:0006363) |
| 0.0 | 2.1 | GO:0003091 | renal water homeostasis(GO:0003091) |
| 0.0 | 3.4 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.4 | GO:1902969 | mitotic DNA replication(GO:1902969) |
| 0.0 | 0.3 | GO:0036444 | calcium ion transmembrane import into mitochondrion(GO:0036444) |
| 0.0 | 0.2 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.0 | 1.4 | GO:0061621 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.0 | 0.6 | GO:1900364 | negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.0 | 1.1 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.0 | 3.6 | GO:0046718 | viral entry into host cell(GO:0046718) |
| 0.0 | 0.4 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
| 0.0 | 0.2 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.0 | 0.2 | GO:0043254 | regulation of protein complex assembly(GO:0043254) |
| 0.0 | 3.0 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.0 | 0.7 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 0.2 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.0 | 1.0 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 2.4 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.0 | 0.3 | GO:0033539 | fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539) |
| 0.0 | 2.5 | GO:0051897 | positive regulation of protein kinase B signaling(GO:0051897) |
| 0.0 | 2.6 | GO:0048704 | embryonic skeletal system morphogenesis(GO:0048704) |
| 0.0 | 0.4 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.0 | 0.7 | GO:2001240 | negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240) |
| 0.0 | 0.2 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.0 | 0.5 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.9 | 5.7 | GO:0075341 | host cell PML body(GO:0075341) |
| 1.2 | 8.7 | GO:0043527 | tRNA methyltransferase complex(GO:0043527) |
| 0.8 | 2.5 | GO:0030689 | Noc complex(GO:0030689) |
| 0.4 | 1.1 | GO:0030956 | glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956) |
| 0.3 | 2.4 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.3 | 5.2 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.3 | 0.9 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
| 0.3 | 3.9 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.3 | 1.6 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.3 | 1.9 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.3 | 2.3 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.3 | 0.8 | GO:0043224 | nuclear SCF ubiquitin ligase complex(GO:0043224) |
| 0.2 | 0.9 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.2 | 6.4 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.2 | 0.7 | GO:0000814 | ESCRT II complex(GO:0000814) |
| 0.2 | 1.6 | GO:0097361 | CIA complex(GO:0097361) |
| 0.2 | 2.7 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.2 | 2.7 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.2 | 2.4 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.2 | 0.9 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.2 | 2.4 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 0.9 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.1 | 2.6 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.1 | 0.6 | GO:0044753 | amphisome(GO:0044753) |
| 0.1 | 1.0 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.1 | 1.1 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.1 | 2.4 | GO:0042405 | nuclear inclusion body(GO:0042405) |
| 0.1 | 0.3 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.1 | 1.9 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 5.2 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.1 | 1.3 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.1 | 0.6 | GO:0032021 | NELF complex(GO:0032021) |
| 0.1 | 2.1 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 0.8 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.1 | 4.0 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.1 | 6.1 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 2.0 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 1.3 | GO:0005687 | U4 snRNP(GO:0005687) |
| 0.1 | 1.4 | GO:0090543 | Flemming body(GO:0090543) |
| 0.1 | 5.0 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 0.5 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.1 | 2.2 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.1 | 1.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.1 | 0.5 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.1 | 6.2 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.5 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 0.6 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 1.7 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 0.4 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.0 | 3.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.0 | 1.0 | GO:0000783 | telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783) |
| 0.0 | 0.2 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.0 | 1.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 0.4 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.7 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 0.8 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.8 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 0.2 | GO:1990393 | 3M complex(GO:1990393) |
| 0.0 | 2.3 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 5.3 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.0 | 1.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 3.8 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 1.8 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.6 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.0 | 0.3 | GO:0043190 | ATP-binding cassette (ABC) transporter complex(GO:0043190) |
| 0.0 | 2.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 2.8 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.0 | 0.2 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 0.0 | 1.2 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 2.8 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 1.0 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 1.1 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.0 | 1.1 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 1.2 | GO:0043657 | host(GO:0018995) host cell(GO:0043657) |
| 0.0 | 0.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 2.7 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 0.3 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.0 | 3.2 | GO:0098858 | actin-based cell projection(GO:0098858) |
| 0.0 | 1.3 | GO:0005901 | caveola(GO:0005901) |
| 0.0 | 0.3 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 5.3 | GO:0016730 | ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731) |
| 1.3 | 5.2 | GO:0016429 | tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429) |
| 1.2 | 3.5 | GO:0019778 | Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779) |
| 1.0 | 8.1 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 0.9 | 3.8 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 0.5 | 1.5 | GO:0097689 | iron channel activity(GO:0097689) |
| 0.5 | 1.4 | GO:0090541 | MIT domain binding(GO:0090541) |
| 0.5 | 1.4 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
| 0.4 | 2.5 | GO:0030144 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144) |
| 0.4 | 1.1 | GO:0050567 | glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567) |
| 0.4 | 2.2 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 0.4 | 1.1 | GO:0004827 | glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827) |
| 0.3 | 1.0 | GO:0003880 | protein C-terminal carboxyl O-methyltransferase activity(GO:0003880) |
| 0.3 | 0.3 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 0.3 | 1.2 | GO:0008518 | reduced folate carrier activity(GO:0008518) |
| 0.3 | 2.0 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.3 | 0.8 | GO:0016744 | transferase activity, transferring aldehyde or ketonic groups(GO:0016744) |
| 0.2 | 0.7 | GO:0030366 | molybdopterin synthase activity(GO:0030366) |
| 0.2 | 1.1 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.2 | 4.0 | GO:0016423 | tRNA (guanine) methyltransferase activity(GO:0016423) |
| 0.2 | 5.7 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.2 | 6.4 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.2 | 1.6 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.2 | 2.8 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.2 | 3.2 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.2 | 0.5 | GO:0061711 | N(6)-L-threonylcarbamoyladenine synthase(GO:0061711) |
| 0.2 | 1.1 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.2 | 1.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 3.6 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.1 | 1.3 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.1 | 1.3 | GO:0030621 | U4 snRNA binding(GO:0030621) |
| 0.1 | 0.8 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.1 | 0.9 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.1 | 9.2 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.1 | 0.9 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.1 | 0.6 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.1 | 1.1 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
| 0.1 | 1.6 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 0.6 | GO:0008240 | tripeptidyl-peptidase activity(GO:0008240) |
| 0.1 | 4.8 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.1 | 1.0 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.1 | 8.1 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.1 | 5.6 | GO:0003954 | NADH dehydrogenase activity(GO:0003954) |
| 0.1 | 0.8 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.1 | 0.2 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 0.1 | 1.2 | GO:0015232 | heme transporter activity(GO:0015232) |
| 0.1 | 1.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 2.3 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 2.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.1 | 2.4 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.1 | 0.2 | GO:0004127 | cytidylate kinase activity(GO:0004127) |
| 0.1 | 1.3 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
| 0.1 | 0.4 | GO:0016802 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.1 | 1.7 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.1 | 2.0 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 0.1 | 3.2 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.1 | 1.0 | GO:0098505 | G-rich strand telomeric DNA binding(GO:0098505) |
| 0.1 | 0.3 | GO:0016402 | pristanoyl-CoA oxidase activity(GO:0016402) |
| 0.0 | 0.2 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 0.0 | 1.3 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.0 | 1.6 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.4 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.0 | 0.8 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 0.0 | 0.3 | GO:0000182 | rDNA binding(GO:0000182) |
| 0.0 | 0.0 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
| 0.0 | 1.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 2.0 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.2 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.0 | 4.0 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 3.9 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.9 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 3.4 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
| 0.0 | 2.5 | GO:0004497 | monooxygenase activity(GO:0004497) |
| 0.0 | 2.3 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 0.4 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 1.4 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.9 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.0 | 2.2 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.1 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 0.0 | 0.6 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.9 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 1.1 | GO:0020037 | heme binding(GO:0020037) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 1.0 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 0.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 2.0 | ST T CELL SIGNAL TRANSDUCTION | T Cell Signal Transduction |
| 0.0 | 1.6 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 2.8 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 1.8 | PID CXCR4 PATHWAY | CXCR4-mediated signaling events |
| 0.0 | 1.0 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 1.0 | PID BMP PATHWAY | BMP receptor signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.4 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.2 | 2.2 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.2 | 2.6 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.1 | 3.2 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 1.4 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.1 | 5.7 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 1.9 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.1 | 3.8 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.1 | 5.0 | REACTOME RNA POL III TRANSCRIPTION | Genes involved in RNA Polymerase III Transcription |
| 0.1 | 6.4 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 1.0 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.1 | 2.7 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.1 | 3.6 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.1 | 3.9 | REACTOME IRON UPTAKE AND TRANSPORT | Genes involved in Iron uptake and transport |
| 0.0 | 2.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 1.3 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |
| 0.0 | 0.7 | REACTOME G2 M DNA DAMAGE CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.0 | 1.0 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 4.0 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.0 | 4.0 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 1.4 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 1.1 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 2.1 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |
| 0.0 | 0.7 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.7 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 1.3 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 1.5 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |