ISMARA results: CREB3L1

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CREB3L1_CREB3

Z-value: 0.24

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Transcription factors associated with CREB3L1_CREB3

Gene Symbol	Gene ID	Gene Info
CREB3L1 Ensembl NCBI GeneCards UniProt	ENSG00000157613.6	cAMP responsive element binding protein 3 like 1
CREB3 Ensembl NCBI GeneCards UniProt	ENSG00000107175.6	cAMP responsive element binding protein 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CREB3L1	hg19_v2_chr11_+_46316677_46316719	0.31	1.8e-01	Click!
CREB3	hg19_v2_chr9_+_35732312_35732332	-0.03	8.9e-01	Click!

Activity profile of CREB3L1_CREB3 motif

Sorted Z-values of CREB3L1_CREB3 motif

No targets for CREB3L1_CREB3

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L1_CREB3

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0015728	mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0	0.7	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.6	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.1	0.4	GO:0036483	neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.0	0.4	GO:0042695	thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0	0.4	GO:0090204	protein localization to nuclear pore(GO:0090204)
0.0	0.4	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.4	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.4	GO:0016180	snRNA processing(GO:0016180)
0.1	0.3	GO:0048698	negative regulation of collateral sprouting in absence of injury(GO:0048698)

Showing 1 to 10 of 38 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.0	0.4	GO:0032039	integrator complex(GO:0032039)
0.0	0.4	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.4	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.4	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.1	0.3	GO:1990032	parallel fiber(GO:1990032)
0.0	0.3	GO:0070876	SOSS complex(GO:0070876)
0.0	0.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.3	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	0.2	GO:0008623	CHRAC(GO:0008623)

Showing 1 to 10 of 25 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0015130	mevalonate transmembrane transporter activity(GO:0015130)
0.1	0.7	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0	0.5	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.5	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.4	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1	0.3	GO:1902271	D3 vitamins binding(GO:1902271)
0.0	0.3	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.0	0.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.3	GO:0046870	cadmium ion binding(GO:0046870)
0.0	0.3	GO:0022841	potassium ion leak channel activity(GO:0022841)

Showing 1 to 10 of 24 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
0.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway

Showing 1 to 3 of 3 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Total log-likelihood	Term	Description
0.8	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.3	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation

Showing 1 to 5 of 5 entries

Results for CREB3L1_CREB3

Z-value: 0.24

Motif logo

Transcription factors associated with CREB3L1_CREB3

Activity-expression correlation:

Activity profile of CREB3L1_CREB3 motif

Sorted Z-values of CREB3L1_CREB3 motif

No targets for CREB3L1_CREB3

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L1_CREB3

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: