ISMARA results: CREB3L2

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CREB3L2

Z-value: 1.28

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Transcription factors associated with CREB3L2

Gene Symbol	Gene ID	Gene Info
CREB3L2 Ensembl NCBI GeneCards UniProt	ENSG00000182158.10	cAMP responsive element binding protein 3 like 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CREB3L2	hg19_v2_chr7_-_137686791_137686821	-0.06	8.1e-01	Click!

Activity profile of CREB3L2 motif

Sorted Z-values of CREB3L2 motif

No targets for CREB3L2

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.0	GO:0015816	glycine transport(GO:0015816)
0.6	2.8	GO:0030807	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0	2.8	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.7	2.2	GO:0051780	mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.2	2.1	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1	2.1	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.1	1.9	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	1.7	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.3	1.6	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.2	1.6	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)

Showing 1 to 10 of 93 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	3.0	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.0	3.0	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0	2.9	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	2.6	GO:0030672	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	2.0	GO:0005604	basement membrane(GO:0005604)
0.0	1.7	GO:0015030	Cajal body(GO:0015030)
0.1	1.5	GO:0002116	semaphorin receptor complex(GO:0002116)
0.1	1.5	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	1.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	1.5	GO:0035578	azurophil granule lumen(GO:0035578)

Showing 1 to 10 of 41 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.0	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.2	2.8	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	2.8	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	2.5	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	2.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.7	2.2	GO:0015130	mevalonate transmembrane transporter activity(GO:0015130)
0.0	1.8	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0	1.7	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.5	1.6	GO:0008859	exoribonuclease II activity(GO:0008859)
0.1	1.6	GO:0008199	ferric iron binding(GO:0008199)

Showing 1 to 10 of 66 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.8	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	2.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.1	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	1.1	PID FOXO PATHWAY	FoxO family signaling
0.0	0.8	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.5	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway

Showing 1 to 7 of 7 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.8	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	2.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	2.4	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.1	2.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	1.9	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.5	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	1.5	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.0	1.3	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	1.2	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.9	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism

Showing 1 to 10 of 18 entries

Results for CREB3L2

Z-value: 1.28

Motif logo

Transcription factors associated with CREB3L2

Activity-expression correlation:

Activity profile of CREB3L2 motif

Sorted Z-values of CREB3L2 motif

No targets for CREB3L2

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: