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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for CREB5_CREM_JUNB
Z-value: 1.41
Motif logo
Transcription factors associated with CREB5_CREM_JUNB
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
CREB5
|
ENSG00000146592.12 | cAMP responsive element binding protein 5 |
|
CREM
|
ENSG00000095794.15 | cAMP responsive element modulator |
|
JUNB
|
ENSG00000171223.4 | JunB proto-oncogene, AP-1 transcription factor subunit |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| JUNB | hg19_v2_chr19_+_12902289_12902310 | -0.94 | 8.9e-10 | Click! |
| CREB5 | hg19_v2_chr7_+_28725585_28725608 | 0.77 | 7.0e-05 | Click! |
| CREM | hg19_v2_chr10_+_35484053_35484076 | -0.75 | 1.5e-04 | Click! |
Activity profile of CREB5_CREM_JUNB motif
Sorted Z-values of CREB5_CREM_JUNB motif
Network of associatons between targets according to the STRING database.
First level regulatory network of CREB5_CREM_JUNB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 5.5 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 1.1 | 3.4 | GO:1904235 | regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237) |
| 1.1 | 3.2 | GO:0021503 | neural fold bending(GO:0021503) |
| 0.9 | 2.7 | GO:0035022 | positive regulation of Rac protein signal transduction(GO:0035022) |
| 0.9 | 2.7 | GO:1902598 | creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598) |
| 0.8 | 4.9 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.8 | 2.3 | GO:1990108 | protein linear deubiquitination(GO:1990108) |
| 0.6 | 3.1 | GO:0071500 | cellular response to nitrosative stress(GO:0071500) |
| 0.6 | 6.6 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
| 0.6 | 2.9 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
| 0.6 | 1.7 | GO:0060382 | regulation of DNA strand elongation(GO:0060382) |
| 0.6 | 1.7 | GO:2000681 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 0.5 | 5.4 | GO:0042695 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
| 0.5 | 3.6 | GO:0043163 | cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229) |
| 0.5 | 2.5 | GO:0060266 | negative regulation of respiratory burst involved in inflammatory response(GO:0060266) |
| 0.5 | 2.9 | GO:0090135 | actin filament branching(GO:0090135) |
| 0.4 | 3.9 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.4 | 1.7 | GO:0061582 | intestinal epithelial cell migration(GO:0061582) |
| 0.4 | 1.3 | GO:1903452 | regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452) |
| 0.4 | 2.4 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.4 | 1.2 | GO:0021896 | forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) gamma-aminobutyric acid secretion, neurotransmission(GO:0061534) |
| 0.4 | 2.3 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
| 0.4 | 1.8 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.4 | 2.8 | GO:2000323 | negative regulation of glucocorticoid receptor signaling pathway(GO:2000323) |
| 0.3 | 7.0 | GO:0031268 | pseudopodium organization(GO:0031268) |
| 0.3 | 1.4 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 0.3 | 1.0 | GO:1990519 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 0.3 | 6.5 | GO:0010510 | regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) |
| 0.3 | 1.3 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 0.3 | 1.2 | GO:0071684 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 0.3 | 1.4 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 0.3 | 11.1 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
| 0.3 | 2.2 | GO:0060702 | negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) |
| 0.3 | 3.0 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.3 | 1.9 | GO:1903332 | regulation of protein folding(GO:1903332) |
| 0.3 | 1.3 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.3 | 4.0 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.3 | 0.8 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 0.3 | 3.1 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
| 0.3 | 3.1 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.3 | 0.8 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 0.2 | 2.5 | GO:0060244 | negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052) |
| 0.2 | 3.7 | GO:0061042 | vascular wound healing(GO:0061042) |
| 0.2 | 2.9 | GO:0019367 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.2 | 3.8 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.2 | 8.5 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.2 | 4.3 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.2 | 0.7 | GO:0006117 | acetaldehyde metabolic process(GO:0006117) |
| 0.2 | 1.5 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.2 | 1.5 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.2 | 1.1 | GO:0035617 | stress granule disassembly(GO:0035617) |
| 0.2 | 1.5 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.2 | 5.2 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 0.2 | 0.8 | GO:0097252 | oligodendrocyte apoptotic process(GO:0097252) |
| 0.2 | 1.2 | GO:0032911 | negative regulation of transforming growth factor beta1 production(GO:0032911) |
| 0.2 | 1.2 | GO:0061034 | olfactory bulb mitral cell layer development(GO:0061034) |
| 0.2 | 0.6 | GO:0090271 | positive regulation of fibroblast growth factor production(GO:0090271) |
| 0.2 | 1.4 | GO:0051414 | response to cortisol(GO:0051414) |
| 0.2 | 1.2 | GO:2001106 | regulation of modification of synaptic structure(GO:1905244) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.2 | 1.3 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.2 | 2.0 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
| 0.2 | 3.0 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.2 | 0.6 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.2 | 2.8 | GO:0046325 | negative regulation of glucose import(GO:0046325) |
| 0.2 | 8.5 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.2 | 1.9 | GO:0007042 | lysosomal lumen acidification(GO:0007042) |
| 0.2 | 6.6 | GO:0060644 | mammary gland epithelial cell differentiation(GO:0060644) |
| 0.2 | 0.7 | GO:1990637 | response to prolactin(GO:1990637) |
| 0.2 | 0.3 | GO:1901258 | positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258) |
| 0.2 | 0.5 | GO:0034140 | negative regulation of toll-like receptor 3 signaling pathway(GO:0034140) negative regulation of store-operated calcium channel activity(GO:1901340) |
| 0.2 | 3.2 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.2 | 0.5 | GO:0042214 | terpene metabolic process(GO:0042214) epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418) phytoalexin metabolic process(GO:0052314) |
| 0.2 | 2.0 | GO:0060235 | lens induction in camera-type eye(GO:0060235) |
| 0.2 | 4.3 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.2 | 1.8 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.1 | 1.8 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.1 | 1.2 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.1 | 0.7 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 0.1 | 2.5 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.1 | 0.4 | GO:0070898 | RNA polymerase III transcriptional preinitiation complex assembly(GO:0070898) |
| 0.1 | 0.4 | GO:0048075 | positive regulation of eye pigmentation(GO:0048075) |
| 0.1 | 0.5 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 0.1 | 2.4 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.1 | 0.4 | GO:0035905 | ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.1 | 2.7 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.1 | 0.6 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.1 | 1.9 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.1 | 1.1 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 0.7 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.1 | 0.4 | GO:1903660 | negative regulation of complement-dependent cytotoxicity(GO:1903660) |
| 0.1 | 0.3 | GO:0006286 | base-excision repair, base-free sugar-phosphate removal(GO:0006286) |
| 0.1 | 0.9 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.1 | 0.3 | GO:0006429 | glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429) |
| 0.1 | 0.7 | GO:0072642 | interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741) |
| 0.1 | 0.7 | GO:1902963 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.1 | 0.9 | GO:0007000 | nucleolus organization(GO:0007000) |
| 0.1 | 2.1 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.1 | 1.5 | GO:0000050 | urea cycle(GO:0000050) |
| 0.1 | 0.4 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 0.1 | 0.4 | GO:0033484 | nitric oxide homeostasis(GO:0033484) |
| 0.1 | 0.7 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.1 | 1.0 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.1 | 0.6 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.1 | 8.7 | GO:0042771 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771) |
| 0.1 | 2.4 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.1 | 0.6 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.1 | 0.9 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
| 0.1 | 0.6 | GO:0042797 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.1 | 1.4 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.1 | 2.7 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
| 0.1 | 0.9 | GO:0090487 | toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487) |
| 0.1 | 1.2 | GO:0002098 | tRNA wobble uridine modification(GO:0002098) |
| 0.1 | 3.6 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.1 | 1.2 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.1 | 0.3 | GO:0060734 | regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) |
| 0.1 | 1.5 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.1 | 0.1 | GO:0000255 | allantoin metabolic process(GO:0000255) |
| 0.1 | 0.6 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.1 | 1.0 | GO:0034214 | protein hexamerization(GO:0034214) |
| 0.1 | 0.7 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.1 | 4.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.1 | 0.4 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.1 | 1.1 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.1 | 0.6 | GO:0071557 | histone H3-K27 demethylation(GO:0071557) |
| 0.1 | 0.7 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 0.1 | 0.6 | GO:0045955 | negative regulation of calcium ion-dependent exocytosis(GO:0045955) |
| 0.1 | 5.6 | GO:0033275 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.1 | 0.7 | GO:0002943 | tRNA dihydrouridine synthesis(GO:0002943) |
| 0.1 | 1.2 | GO:0061117 | negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of heart growth(GO:0061117) |
| 0.1 | 0.8 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.1 | 0.4 | GO:0030581 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 0.1 | 0.2 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.1 | 0.3 | GO:0043335 | protein unfolding(GO:0043335) |
| 0.1 | 8.2 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.1 | 1.7 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
| 0.1 | 0.3 | GO:0043652 | engulfment of apoptotic cell(GO:0043652) |
| 0.1 | 1.3 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.1 | 0.4 | GO:0090070 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 0.1 | 0.7 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.1 | 1.2 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.1 | 0.8 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
| 0.1 | 0.3 | GO:0072619 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.1 | 0.8 | GO:0040016 | embryonic cleavage(GO:0040016) |
| 0.1 | 0.3 | GO:0021553 | olfactory nerve development(GO:0021553) |
| 0.1 | 0.4 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
| 0.1 | 0.2 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.1 | 0.8 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.1 | 0.3 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.1 | 0.4 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) regulation of protein autoubiquitination(GO:1902498) |
| 0.1 | 1.0 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.1 | 0.3 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 0.1 | 0.4 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.1 | 0.3 | GO:2000690 | regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691) |
| 0.1 | 1.0 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
| 0.1 | 0.5 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
| 0.0 | 0.1 | GO:1900369 | negative regulation of RNA interference(GO:1900369) |
| 0.0 | 2.5 | GO:0007340 | acrosome reaction(GO:0007340) |
| 0.0 | 0.3 | GO:0060161 | positive regulation of dopamine receptor signaling pathway(GO:0060161) |
| 0.0 | 1.5 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 0.4 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.0 | 0.6 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.0 | 0.1 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.0 | 1.1 | GO:0038092 | nodal signaling pathway(GO:0038092) |
| 0.0 | 1.1 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.2 | GO:0002071 | glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) |
| 0.0 | 1.9 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.2 | GO:0010730 | negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle cell proliferation(GO:0014858) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
| 0.0 | 0.9 | GO:0036315 | cellular response to sterol(GO:0036315) |
| 0.0 | 0.3 | GO:0032472 | Golgi calcium ion transport(GO:0032472) |
| 0.0 | 1.4 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
| 0.0 | 0.3 | GO:0006072 | glycerol-3-phosphate metabolic process(GO:0006072) |
| 0.0 | 0.6 | GO:0036155 | acylglycerol acyl-chain remodeling(GO:0036155) |
| 0.0 | 0.5 | GO:0032782 | bile acid secretion(GO:0032782) |
| 0.0 | 0.5 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.0 | 0.2 | GO:1903906 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
| 0.0 | 0.6 | GO:0006105 | succinate metabolic process(GO:0006105) |
| 0.0 | 0.1 | GO:0036451 | cap mRNA methylation(GO:0036451) |
| 0.0 | 1.5 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 0.3 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.0 | 0.1 | GO:0031081 | nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664) |
| 0.0 | 0.9 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.0 | 0.5 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.0 | 0.3 | GO:0040032 | post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828) |
| 0.0 | 0.7 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 0.1 | GO:1904705 | regulation of vascular smooth muscle cell proliferation(GO:1904705) vascular smooth muscle cell proliferation(GO:1990874) |
| 0.0 | 0.5 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
| 0.0 | 0.4 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.0 | 0.6 | GO:2000052 | positive regulation of non-canonical Wnt signaling pathway(GO:2000052) |
| 0.0 | 0.3 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.0 | 1.8 | GO:0033344 | cholesterol efflux(GO:0033344) |
| 0.0 | 0.3 | GO:0021603 | cranial nerve formation(GO:0021603) |
| 0.0 | 1.0 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 0.3 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.0 | 0.3 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 0.0 | 0.9 | GO:0003094 | glomerular filtration(GO:0003094) |
| 0.0 | 0.1 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 0.0 | 0.4 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.0 | 0.3 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.1 | GO:1901096 | regulation of autophagosome maturation(GO:1901096) |
| 0.0 | 0.5 | GO:0031573 | intra-S DNA damage checkpoint(GO:0031573) |
| 0.0 | 0.3 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) |
| 0.0 | 0.2 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 0.0 | 1.5 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.4 | GO:0015871 | choline transport(GO:0015871) |
| 0.0 | 0.5 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 0.0 | 0.6 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.0 | 0.4 | GO:0031116 | positive regulation of microtubule polymerization(GO:0031116) |
| 0.0 | 1.0 | GO:0001844 | protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844) |
| 0.0 | 0.2 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.0 | 0.5 | GO:0007567 | parturition(GO:0007567) |
| 0.0 | 0.4 | GO:0035635 | entry of bacterium into host cell(GO:0035635) |
| 0.0 | 0.5 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.0 | 0.6 | GO:0070374 | positive regulation of ERK1 and ERK2 cascade(GO:0070374) |
| 0.0 | 0.4 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.0 | 0.3 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.0 | 0.2 | GO:1902527 | positive regulation of protein monoubiquitination(GO:1902527) |
| 0.0 | 0.3 | GO:0010815 | bradykinin catabolic process(GO:0010815) |
| 0.0 | 2.9 | GO:0070268 | cornification(GO:0070268) |
| 0.0 | 1.1 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.0 | 0.4 | GO:1902187 | negative regulation of viral release from host cell(GO:1902187) |
| 0.0 | 1.0 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.0 | 0.4 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.0 | 0.3 | GO:2000059 | negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059) |
| 0.0 | 0.3 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.0 | 0.1 | GO:0006983 | ER overload response(GO:0006983) |
| 0.0 | 0.1 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.0 | 4.3 | GO:0006986 | response to unfolded protein(GO:0006986) |
| 0.0 | 0.2 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
| 0.0 | 1.1 | GO:0001947 | heart looping(GO:0001947) |
| 0.0 | 3.6 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.0 | 0.7 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
| 0.0 | 0.3 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.0 | 0.3 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.0 | 0.3 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.0 | 0.3 | GO:0045948 | positive regulation of translational initiation(GO:0045948) |
| 0.0 | 0.8 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 0.5 | GO:0042776 | mitochondrial ATP synthesis coupled proton transport(GO:0042776) |
| 0.0 | 0.1 | GO:2000767 | positive regulation of cytoplasmic translation(GO:2000767) |
| 0.0 | 0.2 | GO:0060149 | negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) |
| 0.0 | 1.8 | GO:0007030 | Golgi organization(GO:0007030) |
| 0.0 | 2.0 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
| 0.0 | 0.3 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.0 | 0.0 | GO:0034371 | chylomicron remodeling(GO:0034371) |
| 0.0 | 0.0 | GO:2001016 | positive regulation of skeletal muscle cell differentiation(GO:2001016) |
| 0.0 | 0.1 | GO:0033082 | regulation of extrathymic T cell differentiation(GO:0033082) |
| 0.0 | 0.7 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.0 | 0.2 | GO:0006397 | mRNA processing(GO:0006397) |
| 0.0 | 0.4 | GO:0043162 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162) |
| 0.0 | 0.1 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.0 | 1.4 | GO:0002456 | T cell mediated immunity(GO:0002456) |
| 0.0 | 0.7 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.4 | GO:0071451 | cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451) |
| 0.0 | 0.5 | GO:0060976 | coronary vasculature development(GO:0060976) |
| 0.0 | 1.0 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.8 | GO:0032508 | DNA duplex unwinding(GO:0032508) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 9.8 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.5 | 1.6 | GO:0075341 | host cell PML body(GO:0075341) |
| 0.4 | 3.1 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.3 | 4.8 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.3 | 2.7 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.3 | 1.6 | GO:0060053 | neurofilament cytoskeleton(GO:0060053) |
| 0.3 | 5.8 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.3 | 0.8 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 0.3 | 5.8 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.3 | 1.8 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.2 | 3.4 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.2 | 1.4 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.2 | 9.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.2 | 7.8 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.2 | 0.7 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) |
| 0.2 | 1.9 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
| 0.2 | 1.3 | GO:0031673 | H zone(GO:0031673) |
| 0.2 | 1.8 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.2 | 2.6 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.2 | 2.1 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.2 | 4.8 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.2 | 3.2 | GO:0005818 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 0.2 | 0.7 | GO:0031084 | BLOC-2 complex(GO:0031084) |
| 0.2 | 1.3 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.2 | 0.6 | GO:0005749 | mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283) |
| 0.2 | 2.6 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.1 | 0.9 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.1 | 1.3 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.1 | 0.4 | GO:0000126 | transcription factor TFIIIB complex(GO:0000126) |
| 0.1 | 0.4 | GO:0031085 | BLOC-3 complex(GO:0031085) |
| 0.1 | 1.9 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 6.8 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 2.5 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 1.8 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.1 | 1.1 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 0.3 | GO:0034272 | phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272) |
| 0.1 | 0.8 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.1 | 5.4 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 1.4 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.1 | 0.6 | GO:0090576 | transcription factor TFIIIC complex(GO:0000127) RNA polymerase III transcription factor complex(GO:0090576) |
| 0.1 | 1.1 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 0.1 | 0.5 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 1.0 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 0.9 | GO:0030478 | actin cap(GO:0030478) |
| 0.1 | 0.5 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
| 0.1 | 1.0 | GO:0070187 | telosome(GO:0070187) |
| 0.1 | 2.6 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.1 | 1.7 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.1 | 5.6 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.1 | 0.4 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
| 0.1 | 2.0 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 1.1 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.0 | 1.2 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 1.4 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 0.8 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.0 | 0.7 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.0 | 0.4 | GO:0005663 | DNA replication factor C complex(GO:0005663) |
| 0.0 | 0.5 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.0 | 0.5 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 1.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 6.7 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 1.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.7 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 3.0 | GO:0030286 | dynein complex(GO:0030286) |
| 0.0 | 0.1 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.0 | 3.2 | GO:0014704 | intercalated disc(GO:0014704) |
| 0.0 | 6.4 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 1.4 | GO:0005921 | gap junction(GO:0005921) |
| 0.0 | 3.5 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 1.7 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.7 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.0 | 0.5 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 1.2 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 0.5 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.0 | 0.7 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 4.8 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.4 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 1.0 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.2 | GO:0032389 | MutLalpha complex(GO:0032389) |
| 0.0 | 1.7 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.3 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.0 | 1.2 | GO:0097542 | ciliary tip(GO:0097542) |
| 0.0 | 0.5 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.0 | 0.3 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.0 | 0.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 0.3 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 3.7 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 1.0 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.0 | 0.7 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 0.4 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 0.0 | 1.8 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 1.5 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 0.1 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
| 0.0 | 0.3 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 0.4 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.4 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.3 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 4.7 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.8 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 0.1 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 0.8 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 2.4 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 2.0 | GO:0030139 | endocytic vesicle(GO:0030139) |
| 0.0 | 0.3 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 0.9 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.2 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 2.8 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 1.6 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 7.1 | GO:0000785 | chromatin(GO:0000785) |
| 0.0 | 1.7 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.0 | 1.9 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
| 0.0 | 0.1 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 2.0 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.8 | GO:0016234 | inclusion body(GO:0016234) |
| 0.0 | 3.2 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 2.0 | GO:0000922 | spindle pole(GO:0000922) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 6.6 | GO:0004741 | [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741) |
| 0.9 | 2.7 | GO:0005308 | creatine transmembrane transporter activity(GO:0005308) |
| 0.9 | 7.1 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 0.8 | 4.9 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.8 | 3.1 | GO:0004142 | diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605) |
| 0.7 | 2.9 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.7 | 4.0 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.5 | 3.1 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.4 | 6.6 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.4 | 1.6 | GO:0070012 | oligopeptidase activity(GO:0070012) |
| 0.4 | 1.1 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.3 | 1.0 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 0.3 | 1.2 | GO:0034602 | oxoglutarate dehydrogenase (NAD+) activity(GO:0034602) |
| 0.3 | 8.5 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.3 | 1.4 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 0.3 | 2.2 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.3 | 3.6 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.3 | 0.8 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 0.3 | 0.8 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
| 0.2 | 1.5 | GO:0032558 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 0.2 | 2.0 | GO:0070137 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.2 | 2.9 | GO:0102338 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.2 | 0.2 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.2 | 0.6 | GO:0051538 | succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538) |
| 0.2 | 0.6 | GO:0000992 | polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) |
| 0.2 | 4.8 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.2 | 1.1 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.2 | 0.9 | GO:0008607 | phosphorylase kinase regulator activity(GO:0008607) |
| 0.2 | 2.3 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.2 | 0.8 | GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616) |
| 0.2 | 0.7 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 0.2 | 1.0 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.2 | 3.9 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.2 | 0.9 | GO:0045174 | oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610) |
| 0.2 | 1.4 | GO:0010853 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 0.2 | 0.5 | GO:0004421 | hydroxymethylglutaryl-CoA synthase activity(GO:0004421) |
| 0.1 | 1.3 | GO:0008467 | [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467) |
| 0.1 | 1.8 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.1 | 3.4 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 0.9 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
| 0.1 | 0.4 | GO:0001156 | TFIIIC-class transcription factor binding(GO:0001156) |
| 0.1 | 0.9 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.1 | 1.6 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.1 | 3.3 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 1.0 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.1 | 4.1 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.1 | 0.4 | GO:0043849 | Ras palmitoyltransferase activity(GO:0043849) |
| 0.1 | 3.8 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.1 | 0.7 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.1 | 0.7 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.1 | 0.3 | GO:0090541 | MIT domain binding(GO:0090541) |
| 0.1 | 0.3 | GO:0004823 | glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823) |
| 0.1 | 2.4 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 1.3 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.1 | 1.2 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.1 | 0.5 | GO:0097677 | STAT family protein binding(GO:0097677) |
| 0.1 | 2.1 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 1.2 | GO:0005172 | vascular endothelial growth factor receptor binding(GO:0005172) |
| 0.1 | 2.8 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 2.6 | GO:0036041 | long-chain fatty acid binding(GO:0036041) |
| 0.1 | 1.2 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.1 | 2.6 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.1 | 0.8 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.1 | 5.4 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 0.7 | GO:0035473 | lipase binding(GO:0035473) |
| 0.1 | 0.8 | GO:0033170 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.1 | 0.9 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.1 | 1.8 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 0.7 | GO:0051880 | G-quadruplex DNA binding(GO:0051880) |
| 0.1 | 3.5 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.1 | 0.1 | GO:0098770 | FBXO family protein binding(GO:0098770) |
| 0.1 | 2.4 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.1 | 3.9 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.1 | 0.4 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 0.1 | 0.6 | GO:0071558 | histone demethylase activity (H3-K27 specific)(GO:0071558) |
| 0.1 | 1.2 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.1 | 2.7 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 0.2 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.1 | 0.7 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
| 0.1 | 2.7 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.1 | 0.5 | GO:0034617 | tetrahydrobiopterin binding(GO:0034617) |
| 0.1 | 1.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.1 | 1.3 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.1 | 0.7 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.1 | 1.9 | GO:0046933 | proton-transporting ATP synthase activity, rotational mechanism(GO:0046933) |
| 0.1 | 2.6 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.1 | 2.7 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 2.9 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.1 | 0.7 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.1 | 0.4 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 0.1 | 3.1 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.1 | 1.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.1 | 0.8 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.1 | 6.7 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 1.3 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 0.8 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 1.1 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.1 | 0.6 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.1 | 0.5 | GO:0004459 | L-lactate dehydrogenase activity(GO:0004459) |
| 0.1 | 1.3 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.1 | 1.3 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.0 | 1.5 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 1.7 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.0 | 0.4 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 0.0 | 3.4 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.0 | 1.9 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 0.3 | GO:0047493 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.0 | 0.2 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
| 0.0 | 2.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 1.1 | GO:0003995 | acyl-CoA dehydrogenase activity(GO:0003995) |
| 0.0 | 0.5 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.0 | 1.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 3.1 | GO:0070888 | E-box binding(GO:0070888) |
| 0.0 | 0.9 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.3 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.0 | 0.3 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.0 | 0.8 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.1 | GO:0004483 | mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483) |
| 0.0 | 0.9 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 1.3 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.0 | 1.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 4.8 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 7.4 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.0 | 1.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.0 | 0.2 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.0 | 1.2 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 2.3 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 1.1 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 1.0 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 1.1 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.0 | 1.3 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.4 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 1.3 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.7 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.0 | 0.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.9 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.0 | 0.0 | GO:0017129 | triglyceride binding(GO:0017129) |
| 0.0 | 0.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.9 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.0 | 2.0 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 0.2 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
| 0.0 | 1.2 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 1.5 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 1.8 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 0.3 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.2 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
| 0.0 | 0.8 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 0.5 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
| 0.0 | 1.1 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 2.8 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 0.1 | GO:0047280 | nicotinamide phosphoribosyltransferase activity(GO:0047280) |
| 0.0 | 1.6 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.1 | GO:0036440 | citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440) |
| 0.0 | 2.7 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 6.4 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 2.7 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 0.3 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 1.1 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.4 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.0 | 0.3 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.0 | 0.1 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 0.0 | 0.1 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.0 | 1.9 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
| 0.0 | 0.1 | GO:0045155 | electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155) |
| 0.0 | 0.3 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.0 | 0.8 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 0.5 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.5 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.0 | 1.6 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.6 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.1 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.0 | 0.3 | GO:0003906 | DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906) |
| 0.0 | 0.8 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
| 0.0 | 5.4 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 2.2 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) |
| 0.0 | 0.5 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 0.4 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.0 | 0.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.0 | 0.3 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.3 | GO:0004871 | signal transducer activity(GO:0004871) |
| 0.0 | 0.1 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.0 | 0.4 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.3 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.0 | 0.0 | GO:0004040 | amidase activity(GO:0004040) |
| 0.0 | 0.2 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.0 | 2.2 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 1.0 | GO:0030145 | manganese ion binding(GO:0030145) |
| 0.0 | 8.9 | GO:0050839 | cell adhesion molecule binding(GO:0050839) |
| 0.0 | 0.3 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 0.3 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.3 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 0.1 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.0 | 0.4 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.5 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 9.7 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.1 | 1.4 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 3.4 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.1 | 6.3 | PID P38 MK2 PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.1 | 1.7 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.1 | 5.3 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.1 | 2.4 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.1 | 0.4 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.1 | 3.3 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.1 | 4.4 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 7.4 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 5.8 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 7.9 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 6.3 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 2.6 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.1 | 1.4 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 2.1 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 2.3 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 2.0 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 3.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.7 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 3.3 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 1.3 | PID WNT NONCANONICAL PATHWAY | Noncanonical Wnt signaling pathway |
| 0.0 | 0.8 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.8 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 0.8 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.2 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 2.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.6 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 1.8 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 1.1 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 0.0 | 2.1 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 6.9 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 2.0 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 0.3 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 1.2 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.0 | 0.2 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.0 | 0.3 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.0 | 0.6 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.0 | 0.7 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 0.9 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.5 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 0.9 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 0.1 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.0 | 1.0 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 0.7 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 5.4 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.3 | 6.5 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.3 | 8.5 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.2 | 7.1 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.2 | 5.4 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.1 | 6.4 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 7.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 2.4 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.1 | 2.9 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.1 | 4.3 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.1 | 5.4 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.1 | 2.6 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.1 | 7.4 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 1.4 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.1 | 1.3 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 1.7 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 1.9 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.1 | 2.4 | REACTOME DESTABILIZATION OF MRNA BY KSRP | Genes involved in Destabilization of mRNA by KSRP |
| 0.1 | 2.1 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.1 | 3.5 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 1.6 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.1 | 1.1 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.1 | 2.5 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.1 | 2.4 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 1.9 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 0.0 | 3.3 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 1.3 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.0 | 0.6 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.0 | 0.8 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 0.5 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 1.9 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 2.2 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.0 | 0.9 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.8 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.5 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 0.0 | 1.7 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 1.5 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.0 | 0.7 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 1.2 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.8 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.5 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.0 | 1.1 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.5 | REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING | Genes involved in Formation of ATP by chemiosmotic coupling |
| 0.0 | 2.8 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.0 | 9.8 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.0 | 2.7 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.8 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 0.0 | 0.2 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.3 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.0 | 0.4 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 1.3 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.3 | REACTOME CIRCADIAN CLOCK | Genes involved in Circadian Clock |
| 0.0 | 1.7 | REACTOME LATE PHASE OF HIV LIFE CYCLE | Genes involved in Late Phase of HIV Life Cycle |
| 0.0 | 1.1 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |