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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CTCF_CTCFL

Z-value: 3.78

Motif logo

Transcription factors associated with CTCF_CTCFL

Gene Symbol Gene ID Gene Info
ENSG00000102974.10 CCCTC-binding factor
ENSG00000124092.8 CCCTC-binding factor like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CTCFLhg19_v2_chr20_-_56100179_561002650.165.1e-01Click!
CTCFhg19_v2_chr16_+_67596310_675963530.106.8e-01Click!

Activity profile of CTCF_CTCFL motif

Sorted Z-values of CTCF_CTCFL motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CTCF_CTCFL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 23.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
3.4 10.2 GO:0043181 vacuolar sequestering(GO:0043181)
3.1 9.4 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
3.1 18.5 GO:1903412 response to bile acid(GO:1903412)
3.1 9.2 GO:0032203 telomere formation via telomerase(GO:0032203)
1.7 30.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
1.3 8.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
1.3 8.0 GO:0031860 telomeric 3' overhang formation(GO:0031860)
1.3 5.3 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
1.3 5.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
1.1 3.4 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
1.1 13.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
1.1 12.0 GO:0030259 lipid glycosylation(GO:0030259)
1.1 4.3 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
1.1 3.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
1.1 5.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
1.1 3.2 GO:0006258 UDP-glucose catabolic process(GO:0006258)
1.1 1.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.9 3.6 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.9 7.3 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.9 7.9 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.9 4.4 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.8 3.4 GO:0035712 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.8 2.5 GO:0090427 activation of meiosis(GO:0090427)
0.8 2.4 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.8 4.7 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.7 6.0 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.7 3.6 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.7 4.4 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.7 7.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.7 6.4 GO:0003010 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.7 5.0 GO:0060263 regulation of respiratory burst(GO:0060263)
0.7 6.3 GO:0035865 cellular response to potassium ion(GO:0035865)
0.7 2.1 GO:0034059 response to anoxia(GO:0034059) positive regulation of penile erection(GO:0060406)
0.7 4.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.7 2.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.6 3.9 GO:0019541 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate metabolic process(GO:0019541) propionate biosynthetic process(GO:0019542)
0.6 1.9 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.6 3.9 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.6 7.7 GO:0035754 B cell chemotaxis(GO:0035754)
0.6 2.4 GO:1904387 cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
0.6 2.4 GO:0042414 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759) epinephrine metabolic process(GO:0042414)
0.6 4.2 GO:0060480 lung goblet cell differentiation(GO:0060480)
0.6 1.8 GO:0015709 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.6 4.7 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.6 1.7 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.6 1.7 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.6 10.3 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.6 2.3 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.6 8.9 GO:0030238 male sex determination(GO:0030238)
0.6 8.9 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.5 4.8 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.5 17.5 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109) linoleic acid metabolic process(GO:0043651)
0.5 1.6 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.5 1.6 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.5 2.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.5 3.0 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.5 3.3 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.5 4.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.5 1.8 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091)
0.5 2.7 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.5 2.3 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.5 3.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.4 3.5 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.4 2.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.4 0.4 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.4 2.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.4 2.8 GO:0046104 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.4 1.2 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.4 1.5 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.4 1.9 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.4 4.8 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.4 10.3 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.4 1.4 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.3 4.5 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 7.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3 8.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 1.7 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3 1.3 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.3 4.7 GO:0007144 female meiosis I(GO:0007144)
0.3 1.7 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.3 3.7 GO:0071316 cellular response to nicotine(GO:0071316)
0.3 1.5 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.3 5.4 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.3 2.4 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.3 1.2 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501) peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.3 5.6 GO:0015671 oxygen transport(GO:0015671)
0.3 1.4 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.3 4.5 GO:0070307 lens fiber cell development(GO:0070307)
0.3 0.9 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.3 1.1 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.3 2.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.3 1.1 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
0.3 0.8 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.3 1.6 GO:0098886 modification of dendritic spine(GO:0098886)
0.3 5.7 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.3 6.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 0.5 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.3 1.3 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.3 1.8 GO:0048478 replication fork protection(GO:0048478)
0.3 1.8 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.3 5.5 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 11.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.2 2.9 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 9.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.2 1.7 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.2 3.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 3.3 GO:0032308 regulation of prostaglandin secretion(GO:0032306) positive regulation of prostaglandin secretion(GO:0032308)
0.2 1.9 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.2 1.6 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.2 3.0 GO:0001887 selenium compound metabolic process(GO:0001887)
0.2 0.7 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2 0.9 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.2 6.3 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway(GO:0035791)
0.2 0.4 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.2 1.0 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.2 1.2 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.2 20.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 1.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 3.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2 1.0 GO:0006490 dolichol-linked oligosaccharide biosynthetic process(GO:0006488) oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.2 2.3 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.2 5.4 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.2 1.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 1.8 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.2 1.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.2 0.2 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.2 0.7 GO:0006272 leading strand elongation(GO:0006272)
0.2 1.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.2 9.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.2 3.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 0.8 GO:0009149 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.2 0.8 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.2 1.9 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 3.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.2 0.6 GO:0046967 cytosol to ER transport(GO:0046967)
0.2 0.5 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.9 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.2 0.6 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.2 3.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.1 1.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.6 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.7 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.7 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.1 0.7 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.7 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 4.3 GO:0060065 uterus development(GO:0060065)
0.1 4.7 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 2.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 4.6 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.1 0.3 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.7 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 11.1 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 0.9 GO:1903232 melanosome assembly(GO:1903232)
0.1 1.3 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.3 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.1 0.9 GO:0044800 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.1 2.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 1.9 GO:0005984 disaccharide metabolic process(GO:0005984)
0.1 1.5 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 3.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.1 4.9 GO:0014002 astrocyte development(GO:0014002)
0.1 1.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 2.4 GO:0051775 response to redox state(GO:0051775)
0.1 0.4 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.1 0.4 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 2.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.7 GO:0030242 pexophagy(GO:0030242)
0.1 1.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.6 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.1 0.5 GO:0015942 10-formyltetrahydrofolate biosynthetic process(GO:0009257) formate metabolic process(GO:0015942)
0.1 0.8 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 2.6 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.1 1.0 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.3 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.7 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 1.2 GO:0032364 oxygen homeostasis(GO:0032364)
0.1 2.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 4.3 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 1.6 GO:1903351 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.1 0.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.5 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.1 1.0 GO:0050808 synapse organization(GO:0050808)
0.1 3.1 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.1 0.7 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1 1.7 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 1.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.6 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.1 5.6 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.1 0.3 GO:1900276 negative regulation of phospholipase C activity(GO:1900275) regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 4.8 GO:0019228 neuronal action potential(GO:0019228)
0.1 1.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.6 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.1 2.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.6 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.1 0.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.3 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 1.5 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.1 1.5 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.8 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.2 GO:0071529 cementum mineralization(GO:0071529)
0.1 0.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 1.7 GO:0021756 striatum development(GO:0021756)
0.1 5.1 GO:0051310 metaphase plate congression(GO:0051310)
0.1 1.1 GO:1902074 response to salt(GO:1902074)
0.1 3.5 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.1 0.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.3 GO:0044691 tooth eruption(GO:0044691)
0.1 0.8 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 1.0 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 2.9 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.2 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 1.0 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.8 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.1 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 4.0 GO:0042073 intraciliary transport(GO:0042073)
0.1 1.6 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.1 1.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.8 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 5.9 GO:0051439 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
0.1 5.9 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.1 0.9 GO:0045023 G0 to G1 transition(GO:0045023)
0.1 1.5 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 1.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 2.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.3 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.1 0.8 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.1 3.3 GO:0006739 NADP metabolic process(GO:0006739)
0.1 0.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.2 GO:0036090 cleavage furrow ingression(GO:0036090)
0.1 1.0 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.0 GO:0006270 DNA replication initiation(GO:0006270)
0.1 1.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 2.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.1 1.5 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 10.7 GO:0051384 response to glucocorticoid(GO:0051384)
0.1 0.2 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 1.8 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 1.9 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.4 GO:0010288 response to lead ion(GO:0010288)
0.1 3.2 GO:0007405 neuroblast proliferation(GO:0007405)
0.1 1.1 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 1.0 GO:0009303 rRNA transcription(GO:0009303)
0.1 4.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.5 GO:0006298 mismatch repair(GO:0006298)
0.1 0.4 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 2.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.5 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.7 GO:0015886 heme transport(GO:0015886)
0.0 0.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 4.5 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.5 GO:0006621 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 1.5 GO:0038202 TORC1 signaling(GO:0038202)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.8 GO:0009125 nucleoside monophosphate catabolic process(GO:0009125)
0.0 2.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 3.9 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 6.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 1.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.5 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0 4.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.6 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.0 0.4 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.7 GO:0031297 replication fork processing(GO:0031297)
0.0 1.2 GO:0050482 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.8 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 1.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.7 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.9 GO:0010165 response to X-ray(GO:0010165)
0.0 0.2 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 1.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.2 GO:0006273 lagging strand elongation(GO:0006273)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.7 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.9 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.5 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.9 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 1.4 GO:0001755 neural crest cell migration(GO:0001755)
0.0 0.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 2.0 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 0.8 GO:0006611 protein export from nucleus(GO:0006611)
0.0 4.3 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.6 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 2.5 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.8 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.8 GO:0045109 intermediate filament organization(GO:0045109)
0.0 2.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 2.1 GO:0035690 cellular response to drug(GO:0035690)
0.0 4.7 GO:0021987 cerebral cortex development(GO:0021987)
0.0 0.3 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 4.1 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.3 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.5 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.0 1.9 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0046602 mitotic centrosome separation(GO:0007100) regulation of mitotic centrosome separation(GO:0046602)
0.0 2.9 GO:0001678 cellular glucose homeostasis(GO:0001678)
0.0 0.1 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.6 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.6 GO:0009988 cell-cell recognition(GO:0009988)
0.0 0.7 GO:0006536 glutamate metabolic process(GO:0006536)
0.0 0.5 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 1.0 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.7 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 1.4 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.2 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.8 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.8 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 2.4 GO:0009566 fertilization(GO:0009566)
0.0 0.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.7 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.0 0.5 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.7 GO:0001947 heart looping(GO:0001947)
0.0 0.1 GO:0055074 calcium ion homeostasis(GO:0055074)
0.0 0.3 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.2 GO:0045008 depyrimidination(GO:0045008)
0.0 0.9 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.0 1.2 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 1.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.0 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.4 GO:0035272 exocrine system development(GO:0035272)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0 0.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.3 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.3 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.6 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 15.8 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
2.1 23.0 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.2 5.0 GO:0000811 GINS complex(GO:0000811)
1.2 12.0 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
1.2 7.2 GO:0097149 centralspindlin complex(GO:0097149)
1.0 10.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.9 4.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.8 2.4 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.7 5.9 GO:1990111 spermatoproteasome complex(GO:1990111)
0.7 8.9 GO:0042788 polysomal ribosome(GO:0042788)
0.6 8.2 GO:0030870 Mre11 complex(GO:0030870)
0.6 2.4 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.6 4.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.6 2.4 GO:0070939 Dsl1p complex(GO:0070939)
0.6 1.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.6 2.9 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.6 4.5 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.6 5.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.5 11.2 GO:0036038 MKS complex(GO:0036038)
0.5 5.6 GO:0005833 hemoglobin complex(GO:0005833)
0.5 3.0 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.5 3.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.5 3.6 GO:0043196 varicosity(GO:0043196)
0.4 1.3 GO:0035101 FACT complex(GO:0035101)
0.4 3.0 GO:0031262 Ndc80 complex(GO:0031262)
0.4 4.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.4 3.9 GO:0031298 replication fork protection complex(GO:0031298)
0.4 5.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.4 2.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.4 4.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.4 1.5 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.4 1.1 GO:0030689 Noc complex(GO:0030689)
0.4 1.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.4 1.1 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.3 2.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 21.1 GO:0001917 photoreceptor inner segment(GO:0001917)
0.3 0.8 GO:0034455 t-UTP complex(GO:0034455)
0.3 6.4 GO:0005861 troponin complex(GO:0005861)
0.3 4.7 GO:0033391 chromatoid body(GO:0033391)
0.3 4.6 GO:0000813 ESCRT I complex(GO:0000813)
0.2 5.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 3.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 4.7 GO:0032059 bleb(GO:0032059)
0.2 7.9 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.2 9.3 GO:0031527 filopodium membrane(GO:0031527)
0.2 1.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2 0.8 GO:0031523 Myb complex(GO:0031523)
0.2 4.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 4.4 GO:0000812 Swr1 complex(GO:0000812)
0.2 1.4 GO:0032807 DNA ligase IV complex(GO:0032807)
0.2 7.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 0.9 GO:0031905 early endosome lumen(GO:0031905)
0.2 2.7 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 1.3 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.2 2.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 1.2 GO:0045298 tubulin complex(GO:0045298)
0.2 6.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 3.7 GO:0035102 PRC1 complex(GO:0035102)
0.2 1.7 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.2 1.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 2.2 GO:0070652 HAUS complex(GO:0070652)
0.2 1.2 GO:0097361 CIA complex(GO:0097361)
0.2 1.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.7 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.1 1.0 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 1.1 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 5.0 GO:0005921 gap junction(GO:0005921)
0.1 0.4 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 2.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.3 GO:0034464 BBSome(GO:0034464)
0.1 0.6 GO:0031417 NatC complex(GO:0031417)
0.1 3.3 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 0.9 GO:0061617 MICOS complex(GO:0061617)
0.1 3.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 0.5 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 3.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.6 GO:0032039 integrator complex(GO:0032039)
0.1 1.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.5 GO:0031931 TORC1 complex(GO:0031931)
0.1 4.7 GO:0000791 euchromatin(GO:0000791)
0.1 11.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.1 0.4 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 9.8 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 17.1 GO:0072562 blood microparticle(GO:0072562)
0.1 0.8 GO:0001939 female pronucleus(GO:0001939) male pronucleus(GO:0001940)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.1 5.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 0.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 5.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.4 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 10.1 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.1 2.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 3.9 GO:0016235 aggresome(GO:0016235)
0.1 7.2 GO:0005902 microvillus(GO:0005902)
0.1 1.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 5.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.0 GO:0008091 spectrin(GO:0008091)
0.1 1.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.1 1.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 0.9 GO:0071439 clathrin complex(GO:0071439)
0.0 0.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 5.5 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 2.7 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.0 1.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 3.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 1.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 56.8 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 10.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.3 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.8 GO:0005840 ribosome(GO:0005840)
0.0 2.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.7 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 10.5 GO:0030133 transport vesicle(GO:0030133)
0.0 1.8 GO:0097542 ciliary tip(GO:0097542)
0.0 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 4.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.7 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 1.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 10.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 3.6 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 2.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.3 GO:0043679 axon terminus(GO:0043679)
0.0 4.9 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 1.7 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.3 GO:0032982 myosin filament(GO:0032982)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 3.5 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.1 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.7 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
3.4 10.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
2.4 12.0 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
2.1 6.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.8 5.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.8 7.0 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
1.6 4.8 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
1.5 18.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.5 8.8 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
1.4 4.2 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
1.3 3.8 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.2 4.9 GO:0031685 adenosine receptor binding(GO:0031685)
1.1 11.2 GO:0008158 hedgehog receptor activity(GO:0008158)
1.1 3.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.0 3.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.0 7.7 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
1.0 2.9 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.9 9.7 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.9 6.0 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.8 7.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.8 4.7 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.7 2.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.7 4.1 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.7 2.0 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.6 5.8 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.6 2.4 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.6 2.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.6 3.0 GO:0098626 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.6 2.4 GO:0035514 DNA demethylase activity(GO:0035514)
0.6 1.8 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.6 10.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.6 1.1 GO:0016530 metallochaperone activity(GO:0016530)
0.6 5.0 GO:0004673 protein histidine kinase activity(GO:0004673)
0.5 4.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.5 2.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.5 28.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.5 2.0 GO:0001601 peptide YY receptor activity(GO:0001601)
0.5 3.5 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.5 2.4 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.5 3.9 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.5 2.8 GO:0004797 thymidine kinase activity(GO:0004797)
0.5 6.4 GO:0031014 troponin T binding(GO:0031014)
0.5 4.5 GO:1990446 U1 snRNP binding(GO:1990446)
0.4 6.6 GO:0019215 intermediate filament binding(GO:0019215)
0.4 8.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.4 1.2 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.4 3.7 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 4.0 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.4 1.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.4 4.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.4 1.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.4 12.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.4 1.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.3 1.0 GO:0052830 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.3 7.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 4.7 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.3 2.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 5.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 13.6 GO:0000217 DNA secondary structure binding(GO:0000217)
0.3 2.2 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.3 5.0 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.3 0.9 GO:0030984 kininogen binding(GO:0030984)
0.3 3.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.3 2.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3 5.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 3.3 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 1.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.3 9.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 9.9 GO:0004697 protein kinase C activity(GO:0004697)
0.3 2.9 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 3.0 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.5 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.2 0.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.9 GO:0099609 microtubule lateral binding(GO:0099609)
0.2 7.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 1.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 0.9 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.2 2.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 6.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 0.7 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2 3.1 GO:0089720 caspase binding(GO:0089720)
0.2 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 0.9 GO:0004122 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.2 0.6 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.2 1.7 GO:0046923 ER retention sequence binding(GO:0046923)
0.2 1.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 1.2 GO:0031705 bombesin receptor binding(GO:0031705)
0.2 1.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.2 9.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 3.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 11.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 11.1 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 3.8 GO:0008061 chitin binding(GO:0008061)
0.2 5.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.2 1.5 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.2 1.7 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 7.7 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 4.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 1.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 5.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.2 2.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.2 2.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.2 0.7 GO:0098808 mRNA cap binding(GO:0098808)
0.2 2.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 1.8 GO:0004645 phosphorylase activity(GO:0004645)
0.2 0.8 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.2 2.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.2 0.5 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2 1.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 2.5 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 0.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 1.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 1.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.9 GO:0046979 TAP2 binding(GO:0046979)
0.1 4.2 GO:0002162 dystroglycan binding(GO:0002162)
0.1 1.7 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.2 GO:0071723 lipopeptide binding(GO:0071723)
0.1 1.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 1.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 2.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 8.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.8 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 2.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 0.9 GO:0032027 myosin light chain binding(GO:0032027)
0.1 0.5 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 1.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 0.5 GO:0004905 type I interferon receptor activity(GO:0004905)
0.1 14.0 GO:0005518 collagen binding(GO:0005518)
0.1 2.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.8 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.1 0.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.7 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 1.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 4.7 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 0.4 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.1 3.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 3.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 1.0 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor(GO:0016655)
0.1 2.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 2.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.7 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.4 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 1.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 1.9 GO:0005542 folic acid binding(GO:0005542)
0.1 2.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 2.2 GO:0032183 SUMO binding(GO:0032183)
0.1 0.6 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 1.0 GO:0042731 PH domain binding(GO:0042731)
0.1 1.4 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 12.2 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.1 4.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 1.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.2 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 2.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.3 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.1 4.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 12.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 25.5 GO:0008017 microtubule binding(GO:0008017)
0.1 0.7 GO:0051434 BH3 domain binding(GO:0051434)
0.1 5.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 1.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 3.7 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 1.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 2.4 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.6 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 1.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 1.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.2 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 1.1 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 1.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 5.3 GO:0046332 SMAD binding(GO:0046332)
0.0 0.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0097677 STAT family protein binding(GO:0097677)
0.0 3.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0030284 mineralocorticoid receptor activity(GO:0017082) estrogen receptor activity(GO:0030284)
0.0 1.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 3.4 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 1.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 1.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 3.2 GO:0005230 extracellular ligand-gated ion channel activity(GO:0005230)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.1 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.8 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.3 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 13.8 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.0 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 0.1 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.8 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.0 0.7 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.4 GO:0051087 chaperone binding(GO:0051087)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 3.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 2.5 GO:0005125 cytokine activity(GO:0005125)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.7 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.8 GO:0002020 protease binding(GO:0002020)
0.0 0.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.2 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.5 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 21.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.4 9.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.3 4.7 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 9.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.3 22.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 17.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 9.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 11.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.2 16.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 18.5 PID FGF PATHWAY FGF signaling pathway
0.1 9.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.9 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 4.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 5.7 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 8.1 PID AURORA B PATHWAY Aurora B signaling
0.1 7.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 3.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.1 2.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 0.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 3.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 5.6 PID PLK1 PATHWAY PLK1 signaling events
0.1 0.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 8.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 5.2 PID P53 REGULATION PATHWAY p53 pathway
0.1 2.3 PID AURORA A PATHWAY Aurora A signaling
0.1 2.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.8 PID ATR PATHWAY ATR signaling pathway
0.0 0.8 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 2.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 3.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.5 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 3.8 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.0 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.8 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 2.1 PID LKB1 PATHWAY LKB1 signaling events
0.0 1.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 1.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 2.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 4.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 4.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 18.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
1.0 24.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.7 19.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.6 17.5 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.5 7.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 15.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.3 8.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.3 4.3 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.3 4.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.3 9.3 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3 12.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.2 5.0 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.2 4.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 8.4 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.2 3.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 12.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.2 6.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.2 3.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 3.5 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2 14.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 0.9 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.2 4.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 9.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 3.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 8.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 2.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 2.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.1 2.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 5.2 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 1.5 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 3.2 REACTOME KINESINS Genes involved in Kinesins
0.1 4.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 2.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 8.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 4.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 5.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 1.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.2 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 1.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 1.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 1.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.5 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 4.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.5 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 6.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 3.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.9 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.7 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 3.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.2 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 5.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.8 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0 0.5 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth
0.0 1.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.7 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.5 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.5 REACTOME SIGNALING BY FGFR1 MUTANTS Genes involved in Signaling by FGFR1 mutants
0.0 0.1 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions