ISMARA results: CXXC1

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CXXC1

Z-value: 3.74

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Transcription factors associated with CXXC1

Gene Symbol	Gene ID	Gene Info
CXXC1 Ensembl NCBI GeneCards UniProt	ENSG00000154832.10	CXXC finger protein 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CXXC1	hg19_v2_chr18_-_47814032_47814079	0.29	2.2e-01	Click!

Activity profile of CXXC1 motif

Sorted Z-values of CXXC1 motif

No targets for CXXC1

Network of associatons between targets according to the STRING database.

First level regulatory network of CXXC1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	11.5	GO:0006999	nuclear pore organization(GO:0006999)
0.5	10.9	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.4	10.9	GO:0051383	kinetochore organization(GO:0051383)
0.6	7.7	GO:0034465	response to carbon monoxide(GO:0034465)
0.5	6.6	GO:0071763	nuclear membrane organization(GO:0071763)
1.9	5.6	GO:0000961	negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.4	5.6	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.6	5.1	GO:0030242	pexophagy(GO:0030242)
0.2	5.0	GO:0051103	DNA ligation involved in DNA repair(GO:0051103)
0.1	5.0	GO:0061462	protein localization to lysosome(GO:0061462)

Showing 1 to 10 of 481 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	16.6	GO:0005637	nuclear inner membrane(GO:0005637)
0.1	13.0	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.7	8.5	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.4	8.5	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.1	8.5	GO:0005901	caveola(GO:0005901)
0.2	8.2	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.3	6.8	GO:0042555	MCM complex(GO:0042555)
0.2	6.7	GO:0043194	axon initial segment(GO:0043194)
0.0	6.6	GO:0001650	fibrillar center(GO:0001650)
0.2	6.1	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)

Showing 1 to 10 of 227 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	8.9	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.9	8.5	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
0.1	8.0	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	7.0	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.1	6.8	GO:0008536	Ran GTPase binding(GO:0008536)
0.2	6.1	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	5.9	GO:0030695	GTPase regulator activity(GO:0030695)
0.6	5.8	GO:0043515	kinetochore binding(GO:0043515)
0.1	5.7	GO:0019894	kinesin binding(GO:0019894)
0.3	5.3	GO:0043024	ribosomal small subunit binding(GO:0043024)

Showing 1 to 10 of 323 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	12.5	PID AURORA B PATHWAY	Aurora B signaling
0.1	9.1	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	8.7	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.1	8.3	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	5.5	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.1	5.0	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.2	4.9	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	4.8	ST G ALPHA I PATHWAY	G alpha i Pathway
0.1	3.9	PID ATR PATHWAY	ATR signaling pathway
0.2	3.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network

Showing 1 to 10 of 61 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	30.2	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.3	16.9	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	8.8	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.4	8.3	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	8.1	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2	8.0	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	7.2	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.1	6.7	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.2	6.0	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.2	5.3	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis

Showing 1 to 10 of 114 entries

Results for CXXC1

Z-value: 3.74

Motif logo

Transcription factors associated with CXXC1

Activity-expression correlation:

Activity profile of CXXC1 motif

Sorted Z-values of CXXC1 motif

No targets for CXXC1

Network of associatons between targets according to the STRING database.

First level regulatory network of CXXC1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: