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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for DPRX
Z-value: 2.51
Motif logo
Transcription factors associated with DPRX
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
DPRX
|
ENSG00000204595.1 | divergent-paired related homeobox |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| DPRX | hg19_v2_chr19_+_54135310_54135310 | -0.10 | 6.8e-01 | Click! |
Activity profile of DPRX motif
Sorted Z-values of DPRX motif
Network of associatons between targets according to the STRING database.
First level regulatory network of DPRX
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.3 | 17.2 | GO:0001808 | negative regulation of type IV hypersensitivity(GO:0001808) |
| 2.2 | 69.1 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 1.7 | 6.8 | GO:0050717 | positive regulation of interleukin-1 alpha secretion(GO:0050717) |
| 1.2 | 3.6 | GO:0002581 | negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) |
| 1.2 | 4.7 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 1.1 | 5.3 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 1.0 | 3.1 | GO:0070175 | positive regulation of enamel mineralization(GO:0070175) |
| 0.9 | 5.2 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.8 | 9.4 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 0.6 | 5.6 | GO:0000023 | maltose metabolic process(GO:0000023) |
| 0.6 | 1.7 | GO:0048633 | negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.5 | 2.2 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.5 | 4.3 | GO:0071494 | cellular response to UV-C(GO:0071494) |
| 0.5 | 4.7 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758) |
| 0.5 | 1.9 | GO:0086092 | regulation of the force of heart contraction by cardiac conduction(GO:0086092) |
| 0.5 | 1.8 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 0.4 | 14.6 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.3 | 1.4 | GO:0035188 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 0.3 | 4.9 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.3 | 0.8 | GO:1903181 | negative regulation of late endosome to lysosome transport(GO:1902823) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166) |
| 0.3 | 2.7 | GO:0045359 | positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.3 | 2.8 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 0.3 | 3.6 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.2 | 0.7 | GO:0072738 | response to diamide(GO:0072737) cellular response to diamide(GO:0072738) |
| 0.2 | 1.7 | GO:0051684 | maintenance of Golgi location(GO:0051684) |
| 0.2 | 4.4 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.2 | 3.3 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.2 | 1.2 | GO:1901909 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.2 | 2.4 | GO:0001915 | negative regulation of T cell mediated cytotoxicity(GO:0001915) |
| 0.2 | 0.8 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
| 0.2 | 0.8 | GO:1903045 | neural crest cell migration involved in sympathetic nervous system development(GO:1903045) |
| 0.2 | 4.3 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.2 | 4.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.2 | 1.7 | GO:2001206 | positive regulation of osteoclast development(GO:2001206) |
| 0.2 | 1.3 | GO:1904690 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.2 | 7.9 | GO:0030511 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.2 | 4.0 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.2 | 0.9 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.2 | 1.2 | GO:0061052 | negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052) |
| 0.1 | 2.3 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.1 | 1.3 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.1 | 0.5 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.1 | 0.4 | GO:0045590 | negative regulation of regulatory T cell differentiation(GO:0045590) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525) |
| 0.1 | 0.9 | GO:0051461 | positive regulation of corticotropin secretion(GO:0051461) |
| 0.1 | 0.9 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.1 | 0.7 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.1 | 0.3 | GO:0035038 | female pronucleus assembly(GO:0035038) |
| 0.1 | 1.4 | GO:0035768 | cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544) |
| 0.1 | 1.9 | GO:1903689 | regulation of wound healing, spreading of epidermal cells(GO:1903689) |
| 0.1 | 0.3 | GO:1904875 | regulation of DNA ligase activity(GO:1904875) |
| 0.1 | 0.3 | GO:2000824 | embryonic heart tube anterior/posterior pattern specification(GO:0035054) negative regulation of androgen receptor activity(GO:2000824) |
| 0.1 | 0.8 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
| 0.1 | 0.8 | GO:0030168 | platelet activation(GO:0030168) |
| 0.1 | 0.8 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.1 | 0.5 | GO:0085032 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.1 | 1.0 | GO:0018377 | protein myristoylation(GO:0018377) |
| 0.1 | 0.3 | GO:0046586 | regulation of calcium-dependent cell-cell adhesion(GO:0046586) |
| 0.1 | 1.4 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 1.4 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.1 | 1.2 | GO:0042428 | serotonin metabolic process(GO:0042428) |
| 0.1 | 0.5 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.1 | 0.6 | GO:0072423 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
| 0.1 | 0.8 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.1 | 0.2 | GO:0070781 | response to biotin(GO:0070781) |
| 0.1 | 0.2 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.1 | 1.8 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.1 | 0.4 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 0.1 | 0.9 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.1 | 0.2 | GO:0048205 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
| 0.1 | 0.4 | GO:0032445 | fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 0.1 | 0.3 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.1 | 0.6 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.1 | 0.5 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.1 | 0.2 | GO:0072108 | positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108) |
| 0.1 | 0.2 | GO:0002101 | tRNA wobble cytosine modification(GO:0002101) |
| 0.1 | 0.6 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 1.5 | GO:2000696 | regulation of epithelial cell differentiation involved in kidney development(GO:2000696) |
| 0.0 | 0.3 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.0 | 0.2 | GO:0002729 | positive regulation of natural killer cell cytokine production(GO:0002729) |
| 0.0 | 0.4 | GO:0097106 | postsynaptic density organization(GO:0097106) |
| 0.0 | 0.3 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.0 | 0.4 | GO:0000389 | mRNA 3'-splice site recognition(GO:0000389) |
| 0.0 | 0.2 | GO:0001757 | somite specification(GO:0001757) |
| 0.0 | 0.4 | GO:1900004 | negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572) |
| 0.0 | 0.8 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.0 | 0.4 | GO:0015825 | L-serine transport(GO:0015825) |
| 0.0 | 1.4 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.0 | 1.1 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.0 | 0.4 | GO:0071670 | smooth muscle cell chemotaxis(GO:0071670) |
| 0.0 | 3.6 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 0.2 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.0 | 0.4 | GO:0035542 | regulation of SNARE complex assembly(GO:0035542) |
| 0.0 | 0.5 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 1.3 | GO:0097178 | ruffle assembly(GO:0097178) |
| 0.0 | 1.6 | GO:0071377 | cellular response to glucagon stimulus(GO:0071377) |
| 0.0 | 0.3 | GO:0043102 | amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267) |
| 0.0 | 0.4 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.0 | 0.2 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.0 | 0.9 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.0 | 0.5 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.0 | 0.5 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 0.2 | GO:0032439 | endosome localization(GO:0032439) |
| 0.0 | 0.5 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.0 | 0.1 | GO:0061364 | apoptotic process involved in luteolysis(GO:0061364) |
| 0.0 | 1.7 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
| 0.0 | 0.8 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.0 | 1.5 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.0 | 0.2 | GO:0030497 | fatty acid elongation(GO:0030497) |
| 0.0 | 0.7 | GO:0048741 | skeletal muscle fiber development(GO:0048741) |
| 0.0 | 7.1 | GO:0010631 | epithelial cell migration(GO:0010631) |
| 0.0 | 0.4 | GO:0006875 | cellular metal ion homeostasis(GO:0006875) |
| 0.0 | 0.5 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.0 | 0.8 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
| 0.0 | 0.4 | GO:0006633 | fatty acid biosynthetic process(GO:0006633) |
| 0.0 | 0.6 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.6 | GO:0033209 | tumor necrosis factor-mediated signaling pathway(GO:0033209) |
| 0.0 | 0.1 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.0 | 0.6 | GO:0007603 | phototransduction, visible light(GO:0007603) |
| 0.0 | 1.2 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.0 | 0.1 | GO:2000321 | interleukin-18 production(GO:0032621) positive regulation of T-helper 17 cell differentiation(GO:2000321) |
| 0.0 | 0.2 | GO:0001763 | morphogenesis of a branching structure(GO:0001763) |
| 0.0 | 1.9 | GO:0045727 | positive regulation of translation(GO:0045727) |
| 0.0 | 1.0 | GO:0007004 | telomere maintenance via telomerase(GO:0007004) |
| 0.0 | 0.2 | GO:0043524 | negative regulation of neuron apoptotic process(GO:0043524) |
| 0.0 | 0.2 | GO:0006264 | mitochondrial DNA replication(GO:0006264) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 11.1 | GO:0097179 | protease inhibitor complex(GO:0097179) |
| 0.5 | 14.6 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.3 | 2.2 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.3 | 64.1 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.3 | 3.9 | GO:0030478 | actin cap(GO:0030478) |
| 0.3 | 2.6 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.2 | 9.4 | GO:0030057 | desmosome(GO:0030057) |
| 0.2 | 3.4 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.2 | 5.3 | GO:0005922 | connexon complex(GO:0005922) |
| 0.2 | 0.5 | GO:0032783 | ELL-EAF complex(GO:0032783) |
| 0.2 | 0.8 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.2 | 0.8 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
| 0.2 | 4.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 0.6 | GO:0031251 | PAN complex(GO:0031251) |
| 0.1 | 2.7 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.1 | 1.9 | GO:0045180 | basal cortex(GO:0045180) |
| 0.1 | 0.9 | GO:0051286 | cell tip(GO:0051286) |
| 0.1 | 0.3 | GO:0070288 | intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288) |
| 0.1 | 0.9 | GO:0034464 | BBSome(GO:0034464) |
| 0.1 | 0.5 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.1 | 4.3 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
| 0.1 | 0.6 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 0.1 | 0.3 | GO:1990075 | kinesin II complex(GO:0016939) periciliary membrane compartment(GO:1990075) |
| 0.1 | 0.3 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.1 | 3.1 | GO:0005605 | basal lamina(GO:0005605) |
| 0.1 | 0.8 | GO:0044754 | autolysosome(GO:0044754) |
| 0.1 | 1.0 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.1 | 2.7 | GO:0030125 | clathrin vesicle coat(GO:0030125) |
| 0.1 | 2.0 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 5.6 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 0.2 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.0 | 4.7 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 0.1 | GO:0098855 | HCN channel complex(GO:0098855) |
| 0.0 | 7.4 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 1.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.3 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.0 | 1.7 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 0.3 | GO:0089701 | U2AF(GO:0089701) |
| 0.0 | 0.3 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.0 | 0.4 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.0 | 1.2 | GO:0071437 | invadopodium(GO:0071437) |
| 0.0 | 0.2 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
| 0.0 | 0.6 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 2.5 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.2 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.0 | 0.7 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.3 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.0 | 0.1 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.0 | 2.0 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 4.7 | GO:1904813 | ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813) |
| 0.0 | 0.5 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.3 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.2 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.0 | 3.5 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.1 | GO:0072559 | NLRP3 inflammasome complex(GO:0072559) |
| 0.0 | 2.6 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 1.4 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 3.6 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 0.2 | GO:0005652 | nuclear lamina(GO:0005652) |
| 0.0 | 0.7 | GO:0000786 | nucleosome(GO:0000786) |
| 0.0 | 0.2 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.1 | GO:1990635 | proximal dendrite(GO:1990635) |
| 0.0 | 0.3 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.0 | 0.2 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 0.5 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 4.5 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.3 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 17.2 | GO:0042015 | interleukin-20 binding(GO:0042015) |
| 0.8 | 9.4 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.6 | 1.9 | GO:0086040 | sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040) |
| 0.6 | 5.6 | GO:0004558 | alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450) |
| 0.6 | 1.8 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 0.6 | 2.4 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
| 0.5 | 2.2 | GO:0034040 | lipid-transporting ATPase activity(GO:0034040) |
| 0.5 | 7.0 | GO:0089720 | caspase binding(GO:0089720) |
| 0.4 | 1.7 | GO:0010348 | lithium:proton antiporter activity(GO:0010348) |
| 0.3 | 7.9 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.3 | 3.6 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.3 | 0.8 | GO:0016503 | pheromone receptor activity(GO:0016503) |
| 0.3 | 2.3 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.2 | 1.0 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.2 | 6.0 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.2 | 4.3 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.2 | 1.2 | GO:0052845 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.2 | 1.8 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
| 0.2 | 3.4 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.2 | 1.7 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.2 | 0.9 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.2 | 0.6 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.1 | 1.8 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 0.6 | GO:0002046 | opsin binding(GO:0002046) |
| 0.1 | 0.7 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.1 | 3.8 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.1 | 3.9 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.1 | 7.4 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 4.9 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 3.0 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.1 | 0.3 | GO:0047150 | betaine-homocysteine S-methyltransferase activity(GO:0047150) |
| 0.1 | 1.3 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.1 | 1.7 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.1 | 0.4 | GO:0016297 | oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297) |
| 0.1 | 0.4 | GO:0000386 | second spliceosomal transesterification activity(GO:0000386) |
| 0.1 | 4.3 | GO:0031369 | translation initiation factor binding(GO:0031369) |
| 0.1 | 0.9 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.1 | 3.0 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.1 | 1.5 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 1.7 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.1 | 0.4 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.1 | 0.4 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.1 | 1.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 0.2 | GO:0017099 | very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099) |
| 0.0 | 0.5 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
| 0.0 | 2.0 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 4.2 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.4 | GO:0005497 | androgen binding(GO:0005497) |
| 0.0 | 0.2 | GO:0070052 | collagen V binding(GO:0070052) |
| 0.0 | 0.3 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 0.0 | 6.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 0.8 | GO:0031748 | D1 dopamine receptor binding(GO:0031748) |
| 0.0 | 4.7 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 0.2 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
| 0.0 | 0.7 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.0 | 1.8 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.6 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.0 | 0.1 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.0 | 0.2 | GO:0004748 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.0 | 1.2 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.0 | 0.4 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 0.3 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.0 | 0.6 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 1.4 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.9 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.0 | 0.4 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 2.3 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.0 | 0.5 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.0 | 0.4 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.0 | 0.8 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.8 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 1.2 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
| 0.0 | 0.5 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.0 | 0.1 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 0.0 | 0.2 | GO:0009374 | biotin binding(GO:0009374) |
| 0.0 | 1.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.5 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.0 | 0.6 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 4.1 | GO:0019838 | growth factor binding(GO:0019838) |
| 0.0 | 0.0 | GO:0050254 | rhodopsin kinase activity(GO:0050254) |
| 0.0 | 0.5 | GO:0043394 | proteoglycan binding(GO:0043394) |
| 0.0 | 1.0 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.3 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.0 | 0.5 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.7 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 1.0 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 0.8 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.1 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 0.1 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 13.4 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.2 | 6.8 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.1 | 0.4 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.1 | 2.0 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.1 | 3.4 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.1 | 7.2 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 8.5 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.2 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 0.7 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.0 | 4.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 3.1 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 2.0 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 1.3 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 0.8 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.0 | 0.6 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 0.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.4 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 0.5 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 1.0 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 0.3 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.3 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 3.0 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 62.0 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.3 | 6.9 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.2 | 5.3 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.2 | 1.7 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.2 | 13.4 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 2.7 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.1 | 7.9 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.1 | 3.6 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 3.0 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 1.9 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 1.4 | REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 | Genes involved in Signaling by activated point mutants of FGFR1 |
| 0.1 | 1.6 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.1 | 2.2 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.1 | 1.2 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.1 | 4.3 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 1.6 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.1 | 1.2 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 2.8 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 4.3 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 1.2 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 0.5 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.0 | 1.0 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 0.8 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 0.0 | 1.0 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.0 | 0.6 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.4 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.2 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.0 | 0.4 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.0 | 0.2 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.0 | 2.3 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.0 | 0.2 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.0 | 0.3 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 2.2 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.2 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |