ISMARA results: DPRX

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for DPRX

Z-value: 2.51

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Transcription factors associated with DPRX

Gene Symbol	Gene ID	Gene Info
DPRX Ensembl NCBI GeneCards UniProt	ENSG00000204595.1	divergent-paired related homeobox

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
DPRX	hg19_v2_chr19_+_54135310_54135310	-0.10	6.8e-01	Click!

Activity profile of DPRX motif

Sorted Z-values of DPRX motif

No targets for DPRX

Network of associatons between targets according to the STRING database.

First level regulatory network of DPRX

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.2	69.1	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
4.3	17.2	GO:0001808	negative regulation of type IV hypersensitivity(GO:0001808)
0.4	14.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.8	9.4	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.2	7.9	GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0	7.1	GO:0010631	epithelial cell migration(GO:0010631)
1.7	6.8	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.6	5.6	GO:0000023	maltose metabolic process(GO:0000023)
1.1	5.3	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
0.9	5.2	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)

Showing 1 to 10 of 125 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	64.1	GO:0031902	late endosome membrane(GO:0031902)
0.5	14.6	GO:0030056	hemidesmosome(GO:0030056)
1.6	11.1	GO:0097179	protease inhibitor complex(GO:0097179)
0.2	9.4	GO:0030057	desmosome(GO:0030057)
0.0	7.4	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	5.6	GO:0005604	basement membrane(GO:0005604)
0.2	5.3	GO:0005922	connexon complex(GO:0005922)
0.0	4.7	GO:0043198	dendritic shaft(GO:0043198)
0.0	4.7	GO:1904813	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0	4.5	GO:0005578	proteinaceous extracellular matrix(GO:0005578)

Showing 1 to 10 of 67 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
2.9	17.2	GO:0042015	interleukin-20 binding(GO:0042015)
0.8	9.4	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.3	7.9	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1	7.4	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.5	7.0	GO:0089720	caspase binding(GO:0089720)
0.2	6.0	GO:0045499	chemorepellent activity(GO:0045499)
0.0	6.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.6	5.6	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.1	4.9	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	4.7	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)

Showing 1 to 10 of 90 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	13.4	NABA COLLAGENS	Genes encoding collagen proteins
0.0	8.5	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	7.2	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.2	6.8	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	4.1	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.1	3.4	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	3.1	PID NOTCH PATHWAY	Notch signaling pathway
0.0	3.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	2.0	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	2.0	PID RHOA PATHWAY	RhoA signaling pathway

Showing 1 to 10 of 22 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	62.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.2	13.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.1	7.9	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.3	6.9	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.2	5.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.1	4.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	4.3	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.1	3.6	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.1	3.0	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	2.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines

Showing 1 to 10 of 34 entries

Results for DPRX

Z-value: 2.51

Motif logo

Transcription factors associated with DPRX

Activity-expression correlation:

Activity profile of DPRX motif

Sorted Z-values of DPRX motif

No targets for DPRX

Network of associatons between targets according to the STRING database.

First level regulatory network of DPRX

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: