ISMARA results: EBF3

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EBF3

Z-value: 2.00

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Transcription factors associated with EBF3

Gene Symbol	Gene ID	Gene Info
EBF3 Ensembl NCBI GeneCards UniProt	ENSG00000108001.9	EBF transcription factor 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
EBF3	hg19_v2_chr10_-_131762105_131762105	0.44	5.4e-02	Click!

Activity profile of EBF3 motif

Sorted Z-values of EBF3 motif

No targets for EBF3

Network of associatons between targets according to the STRING database.

First level regulatory network of EBF3

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	14.6	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
2.9	14.5	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
1.0	7.9	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2	7.7	GO:0022038	corpus callosum development(GO:0022038)
1.2	6.0	GO:1902228	mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
0.0	6.0	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.2	5.3	GO:0032060	bleb assembly(GO:0032060)
0.4	5.2	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.6	5.1	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.7	5.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)

Showing 1 to 10 of 207 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.6	14.0	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1	8.3	GO:0016459	myosin complex(GO:0016459)
0.0	7.1	GO:0005581	collagen trimer(GO:0005581)
0.0	7.1	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	6.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.9	6.0	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.1	5.3	GO:0043218	compact myelin(GO:0043218)
0.1	5.1	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.3	4.5	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
1.1	4.3	GO:0044301	climbing fiber(GO:0044301)

Showing 1 to 10 of 78 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	15.0	GO:0003680	AT DNA binding(GO:0003680)
0.7	14.0	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	6.2	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.7	6.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1	5.5	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	5.3	GO:0016504	peptidase activator activity(GO:0016504)
0.7	5.1	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
1.7	5.0	GO:0070698	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.0	5.0	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.1	4.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)

Showing 1 to 10 of 163 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	15.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	8.1	PID BMP PATHWAY	BMP receptor signaling
0.0	7.4	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	7.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	3.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	3.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	2.8	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	2.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	2.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	2.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events

Showing 1 to 10 of 44 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	14.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.1	5.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	5.2	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	5.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	4.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	4.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	3.6	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	3.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.5	3.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	3.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand

Showing 1 to 10 of 58 entries

Results for EBF3

Z-value: 2.00

Motif logo

Transcription factors associated with EBF3

Activity-expression correlation:

Activity profile of EBF3 motif

Sorted Z-values of EBF3 motif

No targets for EBF3

Network of associatons between targets according to the STRING database.

First level regulatory network of EBF3

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: