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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EBF3

Z-value: 2.00

Motif logo

Transcription factors associated with EBF3

Gene Symbol Gene ID Gene Info
ENSG00000108001.9 EBF transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EBF3hg19_v2_chr10_-_131762105_1317621050.445.4e-02Click!

Activity profile of EBF3 motif

Sorted Z-values of EBF3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EBF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 14.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.4 4.3 GO:0099558 maintenance of synapse structure(GO:0099558)
1.3 2.5 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
1.2 6.0 GO:1902228 mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
1.0 7.9 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.8 2.4 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.7 2.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.7 14.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.7 5.0 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.7 2.1 GO:0090427 activation of meiosis(GO:0090427)
0.6 5.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.6 1.9 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.6 2.9 GO:0032218 riboflavin transport(GO:0032218)
0.5 2.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.5 3.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.4 4.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 5.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.4 1.9 GO:0061150 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.4 1.9 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.3 2.4 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.3 2.4 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659)
0.3 1.0 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.3 1.0 GO:0055073 cadmium ion homeostasis(GO:0055073)
0.3 2.8 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.3 1.3 GO:1990637 response to prolactin(GO:1990637)
0.3 3.6 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.3 1.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.3 3.7 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 1.1 GO:0072248 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.3 1.0 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.3 1.0 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.3 1.3 GO:0042631 cellular response to water deprivation(GO:0042631)
0.3 1.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.2 1.0 GO:0002432 granuloma formation(GO:0002432)
0.2 1.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 4.2 GO:0060242 contact inhibition(GO:0060242)
0.2 5.3 GO:0032060 bleb assembly(GO:0032060)
0.2 1.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 2.7 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 7.7 GO:0022038 corpus callosum development(GO:0022038)
0.2 0.8 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.2 0.6 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.2 1.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2 1.9 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2 0.5 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.2 3.4 GO:0016322 neuron remodeling(GO:0016322)
0.2 1.7 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.2 0.7 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.2 3.5 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.2 0.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.2 0.6 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.2 0.9 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.2 1.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2 0.8 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.2 0.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.2 0.9 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1 2.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 2.8 GO:0005984 disaccharide metabolic process(GO:0005984)
0.1 1.5 GO:0070560 protein secretion by platelet(GO:0070560)
0.1 4.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.7 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.4 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.5 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.4 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 0.5 GO:0090293 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.8 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 1.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.9 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 4.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.5 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.5 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.5 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.1 1.9 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.7 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.5 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 2.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.3 GO:0019085 early viral transcription(GO:0019085)
0.1 0.9 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.1 1.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 1.8 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.8 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.1 0.8 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 1.0 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.7 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.5 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 1.0 GO:1902218 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 1.7 GO:0019532 oxalate transport(GO:0019532)
0.1 3.3 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.1 1.0 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.1 1.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.2 GO:0061508 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1 0.5 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.3 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1 0.3 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.4 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.3 GO:0039507 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.2 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.1 0.2 GO:0061184 Spemann organizer formation(GO:0060061) positive regulation of dermatome development(GO:0061184)
0.1 0.2 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.1 1.0 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.4 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.5 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.2 GO:1903625 negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1 2.0 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.1 0.3 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 1.0 GO:0015886 heme transport(GO:0015886)
0.1 0.5 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.5 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 1.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.2 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.4 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.6 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 1.9 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.4 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 0.1 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.0 0.3 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.5 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 1.6 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0031577 spindle checkpoint(GO:0031577)
0.0 0.9 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0009386 translational attenuation(GO:0009386)
0.0 1.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 1.2 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.5 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 2.0 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 6.0 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.6 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 3.0 GO:0051298 centrosome duplication(GO:0051298)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 1.0 GO:0042438 melanin biosynthetic process(GO:0042438)
0.0 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 1.2 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.5 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0 1.0 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.6 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.1 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0 3.0 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 1.3 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0014054 positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0 0.5 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 1.3 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.3 GO:0006824 cobalt ion transport(GO:0006824)
0.0 1.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.8 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 2.7 GO:0016266 O-glycan processing(GO:0016266)
0.0 1.1 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 1.6 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.3 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.2 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 1.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.7 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.4 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 1.6 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.5 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 1.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.6 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.0 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.6 GO:0009649 entrainment of circadian clock(GO:0009649)
0.0 0.4 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.4 GO:0045332 phospholipid translocation(GO:0045332)
0.0 1.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 2.1 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0 0.6 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.8 GO:0060612 adipose tissue development(GO:0060612)
0.0 2.4 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 1.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.9 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.3 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.3 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 4.7 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.4 GO:0002076 osteoblast development(GO:0002076)
0.0 0.8 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.4 GO:0051289 protein homotetramerization(GO:0051289)
0.0 0.2 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:0044301 climbing fiber(GO:0044301)
0.9 6.0 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.7 3.5 GO:0070701 mucus layer(GO:0070701)
0.6 3.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.6 14.0 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5 3.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.4 1.1 GO:0005608 laminin-3 complex(GO:0005608)
0.3 1.9 GO:0005921 gap junction(GO:0005921)
0.3 1.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 0.9 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.3 4.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 0.6 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 1.3 GO:0019815 B cell receptor complex(GO:0019815)
0.2 1.2 GO:0045298 tubulin complex(GO:0045298)
0.2 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 0.6 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 5.3 GO:0043218 compact myelin(GO:0043218)
0.1 1.3 GO:0032009 early phagosome(GO:0032009)
0.1 0.7 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.5 GO:0032127 dense core granule membrane(GO:0032127)
0.1 1.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 2.4 GO:0034709 methylosome(GO:0034709)
0.1 3.7 GO:0071565 nBAF complex(GO:0071565)
0.1 6.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.1 1.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 2.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.5 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 8.3 GO:0016459 myosin complex(GO:0016459)
0.1 0.8 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 5.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.9 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.5 GO:0070852 cell body fiber(GO:0070852)
0.1 4.2 GO:0001772 immunological synapse(GO:0001772)
0.1 2.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1 1.1 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.9 GO:0032433 filopodium tip(GO:0032433)
0.0 7.1 GO:0005581 collagen trimer(GO:0005581)
0.0 1.0 GO:0042555 MCM complex(GO:0042555)
0.0 0.9 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.2 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 1.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.6 GO:0044754 autolysosome(GO:0044754)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 2.9 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0009346 citrate lyase complex(GO:0009346)
0.0 1.5 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 1.0 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.5 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 1.7 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 7.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 1.1 GO:0030315 T-tubule(GO:0030315)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 2.3 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.1 GO:0005844 polysome(GO:0005844)
0.0 1.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 2.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 1.0 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0070698 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.9 3.5 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.7 6.0 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.7 5.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.7 15.0 GO:0003680 AT DNA binding(GO:0003680)
0.7 14.0 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.6 1.9 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.6 2.9 GO:0032217 riboflavin transporter activity(GO:0032217)
0.5 1.5 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.5 1.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.4 1.3 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.4 1.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.4 2.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.4 4.2 GO:0070097 delta-catenin binding(GO:0070097)
0.4 1.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.3 1.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.3 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.3 1.0 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.3 1.2 GO:0099609 microtubule lateral binding(GO:0099609)
0.3 3.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.3 0.9 GO:0016250 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.3 2.5 GO:0043237 laminin-1 binding(GO:0043237)
0.3 2.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.3 2.4 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.2 1.0 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.2 0.9 GO:0004998 transferrin receptor activity(GO:0004998)
0.2 0.7 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.2 2.9 GO:0032027 myosin light chain binding(GO:0032027)
0.2 0.8 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.2 0.7 GO:0032427 GBD domain binding(GO:0032427)
0.2 1.7 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.5 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 1.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 2.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 3.5 GO:0008432 JUN kinase binding(GO:0008432)
0.2 0.6 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.0 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 2.8 GO:0043295 glutathione binding(GO:0043295)
0.1 1.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.9 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.5 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 1.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 1.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.6 GO:0031208 POZ domain binding(GO:0031208)
0.1 3.0 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.8 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.6 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.4 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 2.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 1.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 4.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 2.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 3.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 4.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 3.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.4 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 5.3 GO:0016504 peptidase activator activity(GO:0016504)
0.1 2.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 1.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.6 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 2.1 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.1 0.2 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.1 0.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.5 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 1.0 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.4 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.3 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.1 5.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.9 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.7 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 3.5 GO:0043621 protein self-association(GO:0043621)
0.0 1.0 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 1.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0001047 core promoter binding(GO:0001047)
0.0 0.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 6.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 1.1 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.2 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 5.0 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.8 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.8 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 0.6 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 4.1 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 3.5 GO:0005518 collagen binding(GO:0005518)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 0.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.1 GO:0003878 ATP citrate synthase activity(GO:0003878)
0.0 1.1 GO:0030507 spectrin binding(GO:0030507)
0.0 2.1 GO:0004620 phospholipase activity(GO:0004620)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 1.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 2.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.0 0.4 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 2.8 GO:0005262 calcium channel activity(GO:0005262)
0.0 2.3 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 2.8 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.4 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.6 GO:0016829 lyase activity(GO:0016829)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.6 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 3.1 GO:0008270 zinc ion binding(GO:0008270)
0.0 0.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.5 GO:0008374 O-acyltransferase activity(GO:0008374)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 3.4 GO:0005125 cytokine activity(GO:0005125)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.6 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.9 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0 0.4 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.4 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.0 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.1 PID BMP PATHWAY BMP receptor signaling
0.1 2.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 3.1 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.3 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 15.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.9 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 2.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 2.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 7.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.2 PID AURORA A PATHWAY Aurora A signaling
0.0 3.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 2.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 2.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 1.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 7.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 1.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.2 PID E2F PATHWAY E2F transcription factor network
0.0 1.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.5 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 14.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 2.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 3.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 1.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 5.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 2.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 4.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 5.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 4.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 5.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 3.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.0 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 2.8 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 3.0 REACTOME KINESINS Genes involved in Kinesins
0.1 1.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.0 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.6 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.8 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 1.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 2.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 2.3 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 3.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 3.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 3.6 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 3.0 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 3.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.9 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 1.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 2.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.3 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis