avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
EBF3 Links Ensembl NCBI GeneCards UniProt	ENSG00000108001.9	EBF transcription factor 3

Gene	Promoter	Pearson corr. coef.	P-value	Plot
EBF3	hg19_v2_chr10_-_131762105_131762105	0.44	5.4e-02	Click!

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Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.9	14.5	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
1.4	4.3	GO:0099558	maintenance of synapse structure(GO:0099558)
1.3	2.5	GO:0060738	epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
1.2	6.0	GO:1902228	mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
1.0	7.9	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.8	2.4	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.7	2.2	GO:0031548	regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.7	14.6	GO:1990573	potassium ion import across plasma membrane(GO:1990573)
0.7	5.0	GO:0007352	zygotic specification of dorsal/ventral axis(GO:0007352)
0.7	2.1	GO:0090427	activation of meiosis(GO:0090427)
0.6	5.1	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.6	1.9	GO:0033967	box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.6	2.9	GO:0032218	riboflavin transport(GO:0032218)
0.5	2.1	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.5	3.5	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.4	4.5	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.4	5.2	GO:0045078	positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.4	1.9	GO:0061150	apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.4	1.9	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.3	2.4	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.3	2.4	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659)
0.3	1.0	GO:0061727	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.3	1.0	GO:0055073	cadmium ion homeostasis(GO:0055073)
0.3	2.8	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.3	1.3	GO:1990637	response to prolactin(GO:1990637)
0.3	3.6	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.3	1.2	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.3	3.7	GO:0019375	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3	1.1	GO:0072248	metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.3	1.0	GO:0000412	histone peptidyl-prolyl isomerization(GO:0000412)
0.3	1.0	GO:0006669	sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.3	1.3	GO:0042631	cellular response to water deprivation(GO:0042631)
0.3	1.0	GO:0044537	regulation of circulating fibrinogen levels(GO:0044537)
0.2	1.0	GO:0002432	granuloma formation(GO:0002432)
0.2	1.7	GO:0007598	blood coagulation, extrinsic pathway(GO:0007598)
0.2	4.2	GO:0060242	contact inhibition(GO:0060242)
0.2	5.3	GO:0032060	bleb assembly(GO:0032060)
0.2	1.9	GO:0007256	activation of JNKK activity(GO:0007256)
0.2	2.7	GO:0031580	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2	7.7	GO:0022038	corpus callosum development(GO:0022038)
0.2	0.8	GO:0010725	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.2	0.6	GO:1903251	multi-ciliated epithelial cell differentiation(GO:1903251)
0.2	1.1	GO:0048022	negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.2	1.9	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.2	0.5	GO:1904530	negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.2	3.4	GO:0016322	neuron remodeling(GO:0016322)
0.2	1.7	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
0.2	0.7	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.2	3.5	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.2	0.5	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.2	0.6	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.2	0.9	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
0.2	1.6	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2	0.8	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.2	0.9	GO:0002378	immunoglobulin biosynthetic process(GO:0002378) negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.2	0.9	GO:0097460	ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.1	2.8	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.1	2.8	GO:0005984	disaccharide metabolic process(GO:0005984)
0.1	1.5	GO:0070560	protein secretion by platelet(GO:0070560)
0.1	4.5	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.1	0.7	GO:0034224	cellular response to zinc ion starvation(GO:0034224)
0.1	0.4	GO:0061536	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1	0.5	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1	0.4	GO:1902283	negative regulation of primary amine oxidase activity(GO:1902283)
0.1	0.5	GO:0090293	nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1	0.8	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	1.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.1	0.9	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1	4.4	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1	0.5	GO:0000415	negative regulation of histone H3-K36 methylation(GO:0000415)
0.1	0.4	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1	0.5	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1	0.5	GO:0071469	cellular response to alkaline pH(GO:0071469)
0.1	1.9	GO:0035372	protein localization to microtubule(GO:0035372)
0.1	1.6	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.1	0.7	GO:0033133	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1	0.5	GO:0036371	protein localization to T-tubule(GO:0036371)
0.1	2.5	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1	0.3	GO:0019085	early viral transcription(GO:0019085)
0.1	0.9	GO:0045144	meiotic sister chromatid segregation(GO:0045144)
0.1	1.2	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.1	1.8	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.1	0.8	GO:0044375	peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.1	0.8	GO:0097461	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1	1.0	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1	0.7	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1	0.5	GO:0060010	Sertoli cell fate commitment(GO:0060010)
0.1	1.0	GO:1902218	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1	1.7	GO:0019532	oxalate transport(GO:0019532)
0.1	3.3	GO:0032201	telomere maintenance via semi-conservative replication(GO:0032201)
0.1	1.0	GO:0071850	mitotic cell cycle arrest(GO:0071850)
0.1	1.0	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.4	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1	0.2	GO:0061508	dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.1	0.5	GO:0097473	cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1	0.3	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.1	0.3	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.1	0.4	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.1	0.2	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
0.1	0.3	GO:0039507	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1	0.2	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.1	0.2	GO:0061184	Spemann organizer formation(GO:0060061) positive regulation of dermatome development(GO:0061184)
0.1	0.2	GO:0038178	complement component C5a signaling pathway(GO:0038178)
0.1	1.0	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1	0.4	GO:0050915	sensory perception of sour taste(GO:0050915)
0.1	0.1	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1	0.8	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.1	0.5	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1	0.2	GO:1903625	negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.1	2.0	GO:0039702	viral budding via host ESCRT complex(GO:0039702)
0.1	0.3	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.1	1.0	GO:0015886	heme transport(GO:0015886)
0.1	0.5	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.5	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.0	1.1	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.0	0.2	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.3	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.0	0.4	GO:0032621	interleukin-18 production(GO:0032621)
0.0	0.5	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.6	GO:0042373	vitamin K metabolic process(GO:0042373)
0.0	1.9	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.4	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
0.0	0.1	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
0.0	0.3	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.0	0.5	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.1	GO:0007509	mesoderm migration involved in gastrulation(GO:0007509)
0.0	1.6	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.3	GO:0050930	induction of positive chemotaxis(GO:0050930)
0.0	0.2	GO:0031577	spindle checkpoint(GO:0031577)
0.0	0.9	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.2	GO:0009386	translational attenuation(GO:0009386)
0.0	1.8	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	1.2	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.2	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.2	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.5	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.2	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	2.0	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	6.0	GO:1990830	response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0	0.8	GO:0006465	signal peptide processing(GO:0006465)
0.0	0.2	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.0	0.6	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.0	0.3	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	3.0	GO:0051298	centrosome duplication(GO:0051298)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.4	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	1.0	GO:0042438	melanin biosynthetic process(GO:0042438)
0.0	0.1	GO:1990535	neuron projection maintenance(GO:1990535)
0.0	1.2	GO:0090383	phagosome acidification(GO:0090383)
0.0	0.5	GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.0	1.0	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.4	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.2	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.8	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.2	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.6	GO:0007501	mesodermal cell fate specification(GO:0007501)
0.0	0.1	GO:0003418	growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0	3.0	GO:0035690	cellular response to drug(GO:0035690)
0.0	0.6	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	1.3	GO:0032007	negative regulation of TOR signaling(GO:0032007)
0.0	0.1	GO:0032252	secretory granule localization(GO:0032252)
0.0	0.7	GO:0021516	dorsal spinal cord development(GO:0021516)
0.0	0.1	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.0	0.5	GO:0048714	positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0	0.2	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	1.3	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.3	GO:0006824	cobalt ion transport(GO:0006824)
0.0	1.2	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	0.5	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.8	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0	2.7	GO:0016266	O-glycan processing(GO:0016266)
0.0	1.1	GO:0032878	regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0	0.5	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	1.6	GO:0080171	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.3	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0	0.2	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	1.9	GO:0071277	cellular response to calcium ion(GO:0071277)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.7	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.4	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	1.6	GO:0030641	regulation of cellular pH(GO:0030641)
0.0	0.2	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.0	0.4	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.5	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.0	1.5	GO:0007029	endoplasmic reticulum organization(GO:0007029)
0.0	0.6	GO:0046475	glycerophospholipid catabolic process(GO:0046475)
0.0	0.0	GO:0002818	intracellular defense response(GO:0002818)
0.0	0.6	GO:0009649	entrainment of circadian clock(GO:0009649)
0.0	0.4	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.4	GO:0045332	phospholipid translocation(GO:0045332)
0.0	1.7	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	2.1	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway(GO:0017015)
0.0	0.4	GO:0050962	detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0	0.2	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.6	GO:0045214	sarcomere organization(GO:0045214)
0.0	0.8	GO:0060612	adipose tissue development(GO:0060612)
0.0	2.4	GO:0001837	epithelial to mesenchymal transition(GO:0001837)
0.0	1.0	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.9	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.3	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.3	GO:1903779	regulation of cardiac conduction(GO:1903779)
0.0	4.7	GO:0006352	DNA-templated transcription, initiation(GO:0006352)
0.0	0.4	GO:0002076	osteoblast development(GO:0002076)
0.0	0.8	GO:0018149	peptide cross-linking(GO:0018149)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	1.4	GO:0051289	protein homotetramerization(GO:0051289)
0.0	0.2	GO:0018146	keratan sulfate biosynthetic process(GO:0018146)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.1	4.3	GO:0044301	climbing fiber(GO:0044301)
0.9	6.0	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.7	3.5	GO:0070701	mucus layer(GO:0070701)
0.6	3.5	GO:0016035	zeta DNA polymerase complex(GO:0016035)
0.6	14.0	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.5	3.3	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.4	1.1	GO:0005608	laminin-3 complex(GO:0005608)
0.3	1.9	GO:0005921	gap junction(GO:0005921)
0.3	1.9	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.3	0.9	GO:0000818	nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.3	4.5	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.2	0.6	GO:0097543	ciliary inversin compartment(GO:0097543)
0.2	1.3	GO:0019815	B cell receptor complex(GO:0019815)
0.2	1.2	GO:0045298	tubulin complex(GO:0045298)
0.2	0.7	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.2	0.6	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.1	5.3	GO:0043218	compact myelin(GO:0043218)
0.1	1.3	GO:0032009	early phagosome(GO:0032009)
0.1	0.7	GO:1990876	cytoplasmic side of nuclear pore(GO:1990876)
0.1	0.5	GO:0032127	dense core granule membrane(GO:0032127)
0.1	1.3	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1	2.4	GO:0034709	methylosome(GO:0034709)
0.1	3.7	GO:0071565	nBAF complex(GO:0071565)
0.1	6.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	1.4	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	1.6	GO:0000137	Golgi cis cisterna(GO:0000137)
0.1	0.4	GO:0045160	myosin I complex(GO:0045160)
0.1	2.0	GO:0000813	ESCRT I complex(GO:0000813)
0.1	0.8	GO:0005787	signal peptidase complex(GO:0005787)
0.1	0.5	GO:0097452	GAIT complex(GO:0097452)
0.1	0.5	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	8.3	GO:0016459	myosin complex(GO:0016459)
0.1	0.8	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.1	5.1	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.1	0.9	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.5	GO:0070852	cell body fiber(GO:0070852)
0.1	4.2	GO:0001772	immunological synapse(GO:0001772)
0.1	2.1	GO:0031231	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.1	1.1	GO:0043020	NADPH oxidase complex(GO:0043020)
0.1	0.9	GO:0032433	filopodium tip(GO:0032433)
0.0	7.1	GO:0005581	collagen trimer(GO:0005581)
0.0	1.0	GO:0042555	MCM complex(GO:0042555)
0.0	0.9	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	1.2	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	1.0	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	0.9	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.6	GO:0031143	pseudopodium(GO:0031143)
0.0	0.8	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.6	GO:0044754	autolysosome(GO:0044754)
0.0	0.6	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	2.9	GO:0005876	spindle microtubule(GO:0005876)
0.0	2.1	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0009346	citrate lyase complex(GO:0009346)
0.0	1.5	GO:0000791	euchromatin(GO:0000791)
0.0	0.3	GO:0042587	glycogen granule(GO:0042587)
0.0	1.0	GO:0009925	basal plasma membrane(GO:0009925)
0.0	1.5	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.9	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.2	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	1.7	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	1.0	GO:0031941	filamentous actin(GO:0031941)
0.0	7.1	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.3	GO:0097433	dense body(GO:0097433)
0.0	1.1	GO:0030315	T-tubule(GO:0030315)
0.0	0.8	GO:0016592	mediator complex(GO:0016592)
0.0	0.8	GO:0005771	multivesicular body(GO:0005771)
0.0	2.3	GO:0043202	lysosomal lumen(GO:0043202)
0.0	1.1	GO:0005844	polysome(GO:0005844)
0.0	1.7	GO:0070821	tertiary granule membrane(GO:0070821)
0.0	0.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.3	GO:0031265	CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0	2.1	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.9	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	1.0	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	0.2	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	5.0	GO:0070698	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617) type I activin receptor binding(GO:0070698)
0.9	3.5	GO:0030760	nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.7	6.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.7	5.1	GO:0008955	peptidoglycan glycosyltransferase activity(GO:0008955)
0.7	15.0	GO:0003680	AT DNA binding(GO:0003680)
0.7	14.0	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.6	1.9	GO:1990259	protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.6	2.9	GO:0032217	riboflavin transporter activity(GO:0032217)
0.5	1.5	GO:0050571	1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.5	1.9	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.4	1.3	GO:0098640	integrin binding involved in cell-matrix adhesion(GO:0098640)
0.4	1.3	GO:0045322	unmethylated CpG binding(GO:0045322)
0.4	2.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.4	4.2	GO:0070097	delta-catenin binding(GO:0070097)
0.4	1.1	GO:0050613	delta14-sterol reductase activity(GO:0050613)
0.3	1.0	GO:0004947	bradykinin receptor activity(GO:0004947)
0.3	1.0	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3	1.0	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.3	1.0	GO:0051139	metal ion:proton antiporter activity(GO:0051139)
0.3	1.2	GO:0099609	microtubule lateral binding(GO:0099609)
0.3	3.6	GO:0001733	galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.3	0.9	GO:0016250	N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.3	2.5	GO:0043237	laminin-1 binding(GO:0043237)
0.3	2.2	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.3	2.4	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.2	1.0	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
0.2	0.9	GO:0004998	transferrin receptor activity(GO:0004998)
0.2	0.7	GO:0004794	L-threonine ammonia-lyase activity(GO:0004794)
0.2	2.9	GO:0032027	myosin light chain binding(GO:0032027)
0.2	0.8	GO:0004583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.2	0.7	GO:0032427	GBD domain binding(GO:0032427)
0.2	1.7	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.2	0.5	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2	1.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.2	2.7	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.2	3.5	GO:0008432	JUN kinase binding(GO:0008432)
0.2	0.6	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1	1.0	GO:0017050	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1	2.8	GO:0043295	glutathione binding(GO:0043295)
0.1	1.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.1	1.9	GO:0070700	BMP receptor binding(GO:0070700)
0.1	0.5	GO:1902122	chenodeoxycholic acid binding(GO:1902122)
0.1	1.2	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
0.1	1.1	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	1.6	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.1	1.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.6	GO:0031208	POZ domain binding(GO:0031208)
0.1	3.0	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	0.8	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1	0.4	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.1	0.6	GO:0003998	acylphosphatase activity(GO:0003998)
0.1	0.4	GO:0052593	tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1	2.4	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	0.4	GO:0070052	collagen V binding(GO:0070052)
0.1	1.7	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.4	GO:0045131	pre-mRNA branch point binding(GO:0045131)
0.1	4.6	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	2.7	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	2.2	GO:0042043	neurexin family protein binding(GO:0042043)
0.1	1.9	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.1	3.3	GO:0003887	DNA-directed DNA polymerase activity(GO:0003887)
0.1	4.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.1	0.4	GO:0086089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1	3.0	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1	0.4	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.1	5.3	GO:0016504	peptidase activator activity(GO:0016504)
0.1	2.5	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1	1.0	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.6	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.1	2.1	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.1	0.2	GO:0004878	complement component C5a receptor activity(GO:0004878)
0.1	0.9	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.1	0.5	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	1.0	GO:0015232	heme transporter activity(GO:0015232)
0.1	0.4	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.3	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	5.5	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.1	0.5	GO:0030348	syntaxin-3 binding(GO:0030348)
0.0	0.9	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.8	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.7	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.4	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0	0.3	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0	1.1	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	3.5	GO:0043621	protein self-association(GO:0043621)
0.0	1.0	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.2	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	1.7	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.3	GO:0001047	core promoter binding(GO:0001047)
0.0	0.6	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.7	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.4	GO:0016215	stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0	6.2	GO:0004860	protein kinase inhibitor activity(GO:0004860)
0.0	1.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.2	GO:0016900	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0	5.0	GO:0008081	phosphoric diester hydrolase activity(GO:0008081)
0.0	0.8	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.8	GO:0017171	serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0	0.6	GO:0051393	alpha-actinin binding(GO:0051393)
0.0	4.1	GO:0008080	N-acetyltransferase activity(GO:0008080)
0.0	1.0	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0	3.5	GO:0005518	collagen binding(GO:0005518)
0.0	1.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.5	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.3	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.3	GO:0015386	potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0	0.8	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	1.8	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.1	GO:0003878	ATP citrate synthase activity(GO:0003878)
0.0	1.1	GO:0030507	spectrin binding(GO:0030507)
0.0	2.1	GO:0004620	phospholipase activity(GO:0004620)
0.0	0.2	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0016015	morphogen activity(GO:0016015)
0.0	0.3	GO:0042834	peptidoglycan binding(GO:0042834)
0.0	1.0	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.8	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	2.1	GO:0002039	p53 binding(GO:0002039)
0.0	0.2	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.0	0.4	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0008422	beta-glucosidase activity(GO:0008422)
0.0	2.8	GO:0005262	calcium channel activity(GO:0005262)
0.0	2.3	GO:0032947	protein complex scaffold(GO:0032947)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.3	GO:0005522	profilin binding(GO:0005522)
0.0	2.8	GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0	0.2	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.1	GO:0016300	tRNA (uracil) methyltransferase activity(GO:0016300)
0.0	1.0	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.0	0.4	GO:0010857	calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0	0.6	GO:0016829	lyase activity(GO:0016829)
0.0	0.4	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	1.6	GO:0048365	Rac GTPase binding(GO:0048365)
0.0	3.1	GO:0008270	zinc ion binding(GO:0008270)
0.0	0.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	1.0	GO:0050699	WW domain binding(GO:0050699)
0.0	0.5	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
0.0	0.8	GO:0008378	galactosyltransferase activity(GO:0008378)
0.0	0.5	GO:0008374	O-acyltransferase activity(GO:0008374)
0.0	0.3	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.6	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	0.1	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.4	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	3.4	GO:0005125	cytokine activity(GO:0005125)
0.0	0.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.4	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	1.9	GO:0019905	syntaxin binding(GO:0019905)
0.0	0.6	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.0	0.7	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.2	GO:0008527	taste receptor activity(GO:0008527)
0.0	0.9	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.8	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	2.9	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.0	0.4	GO:0098811	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.4	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.2	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.0	GO:0016499	orexin receptor activity(GO:0016499)
0.0	0.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	8.1	PID BMP PATHWAY	BMP receptor signaling
0.1	2.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	3.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	2.1	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	0.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.1	15.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	1.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	1.7	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	2.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	2.6	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	1.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.9	PID IFNG PATHWAY	IFN-gamma pathway
0.0	1.8	PID LKB1 PATHWAY	LKB1 signaling events
0.0	2.8	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	2.1	PID BCR 5PATHWAY	BCR signaling pathway
0.0	7.4	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	1.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	3.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.0	1.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	0.9	PID ATR PATHWAY	ATR signaling pathway
0.0	2.4	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.7	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.8	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	2.2	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.8	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	1.2	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.9	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.9	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	1.2	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	7.0	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	1.0	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.8	PID INSULIN PATHWAY	Insulin Pathway
0.0	1.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.0	0.4	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	1.2	PID RAC1 PATHWAY	RAC1 signaling pathway
0.0	0.9	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	1.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.5	PID CONE PATHWAY	Visual signal transduction: Cones
0.0	1.2	PID E2F PATHWAY	E2F transcription factor network
0.0	1.0	PID FANCONI PATHWAY	Fanconi anemia pathway
0.0	0.5	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	3.4	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2	14.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.2	2.8	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	3.3	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.2	1.3	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.1	5.5	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.1	2.0	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	4.5	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.1	5.0	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.3	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.1	4.4	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	5.2	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	3.1	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.1	1.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	2.8	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	3.0	REACTOME KINESINS	Genes involved in Kinesins
0.1	1.0	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1	2.9	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	2.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	1.0	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	1.6	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0	0.8	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	1.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	1.7	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	2.0	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	2.3	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.0	3.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.8	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	3.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.9	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.7	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.1	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	3.6	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.5	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.5	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.8	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0	3.0	REACTOME DNA REPAIR	Genes involved in DNA Repair
0.0	3.1	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.5	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.4	REACTOME RNA POL I TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase I Transcription Termination
0.0	0.5	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	1.9	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	0.2	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	1.1	REACTOME PPARA ACTIVATES GENE EXPRESSION	Genes involved in PPARA Activates Gene Expression
0.0	2.9	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.5	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0	0.3	REACTOME SEMA4D IN SEMAPHORIN SIGNALING	Genes involved in Sema4D in semaphorin signaling
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	1.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.8	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.3	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis