ISMARA results: EOMES

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EOMES

Z-value: 0.95

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Transcription factors associated with EOMES

Gene Symbol	Gene ID	Gene Info
EOMES Ensembl NCBI GeneCards UniProt	ENSG00000163508.8	eomesodermin

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
EOMES	hg19_v2_chr3_-_27764190_27764208	0.23	3.2e-01	Click!

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

No targets for EOMES

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1	0.8	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
0.0	0.6	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.6	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.1	0.5	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
0.0	0.5	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.5	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1	0.4	GO:1903778	protein localization to vacuolar membrane(GO:1903778)
0.1	0.4	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.0	0.4	GO:0033235	positive regulation of protein sumoylation(GO:0033235)

Showing 1 to 10 of 117 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.7	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.7	GO:0030057	desmosome(GO:0030057)
0.0	0.5	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.5	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.4	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.4	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.4	GO:0045263	proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0	0.4	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.4	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)

Showing 1 to 10 of 41 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	0.6	GO:0070883	pre-miRNA binding(GO:0070883)
0.0	0.6	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0	0.6	GO:0008301	DNA binding, bending(GO:0008301)
0.2	0.5	GO:0008859	exoribonuclease II activity(GO:0008859)
0.0	0.5	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.0	0.5	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1	0.4	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.4	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.4	GO:0022842	leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)

Showing 1 to 10 of 62 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
1.0	PID LKB1 PATHWAY	LKB1 signaling events
0.7	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.6	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.4	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.3	PID MYC PATHWAY	C-MYC pathway
0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway

Showing 1 to 7 of 7 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Total log-likelihood	Term	Description
0.7	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.6	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.4	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.4	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.3	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.3	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.3	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.3	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway

Showing 1 to 10 of 10 entries

Results for EOMES

Z-value: 0.95

Motif logo

Transcription factors associated with EOMES

Activity-expression correlation:

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

No targets for EOMES

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: