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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ETV2

Z-value: 1.09

Motif logo

Transcription factors associated with ETV2

Gene Symbol Gene ID Gene Info
ENSG00000105672.10 ETS variant transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ETV2hg19_v2_chr19_+_36132631_361326950.661.6e-03Click!

Activity profile of ETV2 motif

Sorted Z-values of ETV2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 4.1 GO:0036343 psychomotor behavior(GO:0036343)
0.6 3.0 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.5 2.6 GO:0006203 dGTP catabolic process(GO:0006203)
0.5 2.6 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.5 4.9 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.5 1.8 GO:2000314 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.4 1.8 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.4 1.6 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.4 1.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4 2.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.4 1.8 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.3 2.7 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 1.4 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.3 0.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 1.4 GO:0072709 cellular response to sorbitol(GO:0072709)
0.3 1.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3 1.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.3 1.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.3 1.3 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520)
0.3 1.5 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.3 2.3 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.2 0.7 GO:1900738 dense core granule biogenesis(GO:0061110) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.2 5.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.2 1.8 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.2 1.1 GO:0019303 D-ribose catabolic process(GO:0019303)
0.2 1.1 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 1.5 GO:1903232 melanosome assembly(GO:1903232)
0.2 0.2 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.2 1.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.2 1.4 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.2 0.2 GO:0000349 generation of catalytic spliceosome for first transesterification step(GO:0000349)
0.2 0.6 GO:0090108 positive regulation of high-density lipoprotein particle assembly(GO:0090108) positive regulation of secretion of lysosomal enzymes(GO:0090340)
0.2 1.8 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.2 0.8 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.2 1.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 0.5 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2 0.5 GO:0043309 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 1.1 GO:0048254 snoRNA localization(GO:0048254)
0.2 1.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.2 0.9 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.2 0.5 GO:0006624 vacuolar protein processing(GO:0006624)
0.2 1.0 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 1.6 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.2 0.5 GO:0046041 ITP metabolic process(GO:0046041)
0.2 6.0 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.2 0.8 GO:0090182 regulation of secretion of lysosomal enzymes(GO:0090182)
0.2 0.5 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 0.6 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 1.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 0.7 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 3.0 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.5 GO:0061743 motor learning(GO:0061743)
0.1 0.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.1 1.0 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.4 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.9 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 0.8 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.4 GO:2000276 negative regulation of histone phosphorylation(GO:0033128) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.1 0.5 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.5 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.1 2.3 GO:0045008 depyrimidination(GO:0045008)
0.1 0.4 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 0.3 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 1.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.4 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.3 GO:0043132 NAD transport(GO:0043132)
0.1 0.7 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.3 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.1 0.3 GO:2000395 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 1.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.8 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.4 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.6 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.8 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 1.7 GO:0050713 negative regulation of interleukin-1 beta secretion(GO:0050713)
0.1 0.3 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.3 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.4 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1 0.5 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.1 1.5 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.1 0.3 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 1.0 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.6 GO:0019075 virus maturation(GO:0019075)
0.1 1.7 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1 0.7 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.5 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1 0.3 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.4 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.1 0.4 GO:0032526 response to retinoic acid(GO:0032526)
0.1 0.3 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.3 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.3 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 1.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.6 GO:0007144 female meiosis I(GO:0007144)
0.1 0.9 GO:1903441 receptor localization to nonmotile primary cilium(GO:0097500) protein localization to ciliary membrane(GO:1903441)
0.1 0.4 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.1 0.4 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.2 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 1.5 GO:0042424 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 0.3 GO:0061511 centriole elongation(GO:0061511)
0.1 1.9 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.0 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.3 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 1.9 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.4 GO:0021539 subthalamus development(GO:0021539)
0.1 0.3 GO:0036071 N-glycan fucosylation(GO:0036071)
0.1 0.6 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.1 0.4 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.9 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.2 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.1 3.8 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.2 GO:0015677 copper ion import(GO:0015677)
0.1 1.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.9 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.1 0.6 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.1 1.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 1.0 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 9.4 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 1.4 GO:0006265 DNA topological change(GO:0006265)
0.1 0.9 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.1 0.4 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.3 GO:0034227 tRNA thio-modification(GO:0034227)
0.1 1.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 0.8 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.7 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 6.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 1.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.8 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
0.1 0.4 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.1 1.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.2 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.1 0.4 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.4 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 0.5 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.5 GO:0002223 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.3 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.5 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.3 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.9 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.2 GO:0052056 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.9 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.1 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.4 GO:0035268 protein mannosylation(GO:0035268) protein O-linked mannosylation(GO:0035269)
0.0 2.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.3 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.8 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.2 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.2 GO:0006382 adenosine to inosine editing(GO:0006382)
0.0 0.6 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781) protein O-linked fucosylation(GO:0036066)
0.0 0.7 GO:0015886 heme transport(GO:0015886)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.9 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.6 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.2 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.3 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.4 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.9 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0051801 cytolysis by symbiont of host cells(GO:0001897) hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) cytolysis in other organism involved in symbiotic interaction(GO:0051801) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.7 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.5 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 1.0 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0 0.5 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.1 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.0 0.2 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 1.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.5 GO:0090520 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0043486 histone exchange(GO:0043486)
0.0 0.5 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.2 GO:0033504 floor plate development(GO:0033504)
0.0 0.1 GO:0007500 mesodermal cell fate determination(GO:0007500) negative regulation of intracellular transport of viral material(GO:1901253)
0.0 0.2 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.6 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.4 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 2.7 GO:0043462 regulation of ATPase activity(GO:0043462)
0.0 0.2 GO:0002467 germinal center formation(GO:0002467)
0.0 0.9 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.2 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.0 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.2 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.2 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.1 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 1.0 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 0.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 1.6 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803)
0.0 1.1 GO:0007566 embryo implantation(GO:0007566)
0.0 0.9 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.6 GO:0030488 tRNA methylation(GO:0030488)
0.0 1.1 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.3 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.8 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.2 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.0 0.7 GO:0042407 cristae formation(GO:0042407)
0.0 1.4 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.6 GO:0071801 regulation of podosome assembly(GO:0071801)
0.0 0.4 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0090042 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.0 0.6 GO:0008209 androgen metabolic process(GO:0008209)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 1.0 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0001916 positive regulation of T cell mediated cytotoxicity(GO:0001916)
0.0 0.1 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.3 GO:0050900 leukocyte migration(GO:0050900)
0.0 0.1 GO:0042426 choline catabolic process(GO:0042426)
0.0 0.6 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.0 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.4 GO:0006400 tRNA modification(GO:0006400)
0.0 0.6 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0032302 MutSbeta complex(GO:0032302)
0.4 3.5 GO:0005683 U7 snRNP(GO:0005683)
0.4 1.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.3 1.8 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.3 0.9 GO:0044609 DBIRD complex(GO:0044609)
0.3 1.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.3 1.6 GO:0097149 centralspindlin complex(GO:0097149)
0.3 1.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.2 2.6 GO:0005687 U4 snRNP(GO:0005687)
0.2 2.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 3.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.2 3.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 1.0 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.2 0.6 GO:0035101 FACT complex(GO:0035101)
0.2 1.1 GO:0071817 MMXD complex(GO:0071817)
0.2 0.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 1.4 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 2.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 1.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.6 GO:0097255 R2TP complex(GO:0097255)
0.1 0.9 GO:0035061 interchromatin granule(GO:0035061)
0.1 1.3 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.1 1.2 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.7 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.4 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.6 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.6 GO:1990031 pinceau fiber(GO:1990031)
0.1 1.8 GO:0016600 flotillin complex(GO:0016600)
0.1 0.2 GO:0071010 prespliceosome(GO:0071010)
0.1 1.7 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.7 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.1 0.8 GO:0043196 varicosity(GO:0043196)
0.1 1.6 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.6 GO:0089701 U2AF(GO:0089701)
0.1 0.7 GO:0061617 MICOS complex(GO:0061617)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.6 GO:0098536 deuterosome(GO:0098536)
0.1 0.2 GO:0019034 viral replication complex(GO:0019034)
0.1 8.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 1.1 GO:0008278 cohesin complex(GO:0008278)
0.1 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.1 1.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.9 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.4 GO:0032044 DSIF complex(GO:0032044)
0.1 5.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 4.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.4 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 1.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.4 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.1 0.6 GO:0034709 methylosome(GO:0034709)
0.1 4.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 6.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.7 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.7 GO:0034464 BBSome(GO:0034464)
0.0 1.3 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 1.2 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.7 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 1.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.5 GO:0043219 lateral loop(GO:0043219)
0.0 0.3 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0019815 B cell receptor complex(GO:0019815)
0.0 4.3 GO:0005776 autophagosome(GO:0005776)
0.0 2.9 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 2.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 1.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 1.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.0 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.4 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.3 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.0 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.3 GO:0005685 U1 snRNP(GO:0005685)
0.0 1.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.8 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.3 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.1 GO:0044447 axoneme part(GO:0044447)
0.0 1.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 6.0 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.9 2.6 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.5 3.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.5 1.9 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.4 2.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.4 1.3 GO:0032181 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.4 1.1 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.3 1.0 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.3 1.9 GO:0032089 NACHT domain binding(GO:0032089)
0.3 1.9 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.3 1.2 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.3 2.6 GO:0070990 snRNP binding(GO:0070990)
0.3 0.8 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.2 1.0 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.2 4.9 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.2 1.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 0.6 GO:0001133 RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding(GO:0001133)
0.2 0.6 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.2 1.0 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.2 0.9 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.2 0.9 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.2 1.6 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 0.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 2.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.2 1.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 0.5 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.2 0.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 0.9 GO:0016531 copper chaperone activity(GO:0016531)
0.2 2.3 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.2 1.4 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.1 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.1 1.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.0 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.5 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 1.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.4 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.7 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.7 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.4 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.3 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 1.2 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 1.0 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.9 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.6 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.3 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 0.6 GO:0032357 oxidized purine DNA binding(GO:0032357)
0.1 0.6 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.1 0.8 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.5 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.1 0.5 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 1.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.3 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.8 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.3 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.3 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 0.7 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.1 0.2 GO:0080122 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 1.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.9 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.3 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.1 1.3 GO:0070513 death domain binding(GO:0070513)
0.1 0.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 16.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 0.2 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.1 3.0 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.3 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.3 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.1 0.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.2 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.7 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 1.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.8 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.6 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0052856 NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857)
0.0 3.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.3 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 2.8 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 0.9 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.7 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.7 GO:0004871 signal transducer activity(GO:0004871)
0.0 0.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.4 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 1.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.5 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.0 GO:0042007 interleukin-18 binding(GO:0042007)
0.0 0.6 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.6 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 1.1 GO:0005507 copper ion binding(GO:0005507)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 1.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.0 GO:0030109 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.0 0.3 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0046873 metal ion transmembrane transporter activity(GO:0046873)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.7 PID AURORA B PATHWAY Aurora B signaling
0.1 1.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 PID ARF 3PATHWAY Arf1 pathway
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.7 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 1.4 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.8 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.1 PID INSULIN PATHWAY Insulin Pathway
0.0 0.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2 0.3 REACTOME SHC RELATED EVENTS Genes involved in SHC-related events
0.1 3.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 6.0 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.2 REACTOME NUCLEOTIDE EXCISION REPAIR Genes involved in Nucleotide Excision Repair
0.1 4.6 REACTOME KINESINS Genes involved in Kinesins
0.1 13.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 5.1 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 1.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 2.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 1.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 0.6 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 4.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 2.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.9 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.4 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 1.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.3 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)