ISMARA results: ETV6

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ETV6

Z-value: 1.87

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Transcription factors associated with ETV6

Gene Symbol	Gene ID	Gene Info
ETV6 Ensembl NCBI GeneCards UniProt	ENSG00000139083.6	ETS variant transcription factor 6

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ETV6	hg19_v2_chr12_+_11802753_11802834	-0.78	4.8e-05	Click!

Activity profile of ETV6 motif

Sorted Z-values of ETV6 motif

No targets for ETV6

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV6

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.8	6.0	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2	3.9	GO:0031167	rRNA methylation(GO:0031167)
0.0	3.5	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.1	3.4	GO:0050655	dermatan sulfate proteoglycan metabolic process(GO:0050655)
0.1	2.7	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.5	2.5	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1	2.4	GO:0006527	arginine catabolic process(GO:0006527)
0.1	2.4	GO:0001510	RNA methylation(GO:0001510)
0.1	2.3	GO:0051601	exocyst localization(GO:0051601)
0.0	2.3	GO:0016601	Rac protein signal transduction(GO:0016601)

Showing 1 to 10 of 163 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.0	GO:0005581	collagen trimer(GO:0005581)
0.1	3.1	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	2.9	GO:1904115	axon cytoplasm(GO:1904115)
0.0	2.7	GO:0035579	specific granule membrane(GO:0035579)
0.1	2.6	GO:0030914	STAGA complex(GO:0030914)
0.0	2.6	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2	2.5	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.1	2.5	GO:0000145	exocyst(GO:0000145)
0.0	2.4	GO:0005801	cis-Golgi network(GO:0005801)
0.2	2.2	GO:0097255	R2TP complex(GO:0097255)

Showing 1 to 10 of 89 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.0	GO:0005518	collagen binding(GO:0005518)
0.1	3.3	GO:0017091	AU-rich element binding(GO:0017091)
0.1	2.8	GO:0042609	CD4 receptor binding(GO:0042609)
0.3	2.6	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.5	2.5	GO:0015018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3	2.4	GO:0016403	dimethylargininase activity(GO:0016403)
0.2	2.2	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.1	2.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.5	2.1	GO:0016435	rRNA (guanine) methyltransferase activity(GO:0016435)
0.5	2.1	GO:0016429	tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)

Showing 1 to 10 of 107 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
6.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
2.5	PID MYC PATHWAY	C-MYC pathway
2.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
2.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
2.0	PID FANCONI PATHWAY	Fanconi anemia pathway
1.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
1.5	PID AURORA A PATHWAY	Aurora A signaling
1.2	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
1.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
1.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity

Showing 1 to 10 of 15 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.7	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	2.7	REACTOME KINESINS	Genes involved in Kinesins
0.2	2.5	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1	2.5	REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS	Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0	2.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	2.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	2.2	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	2.2	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	1.9	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	1.9	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis

Showing 1 to 10 of 44 entries

Results for ETV6

Z-value: 1.87

Motif logo

Transcription factors associated with ETV6

Activity-expression correlation:

Activity profile of ETV6 motif

Sorted Z-values of ETV6 motif

No targets for ETV6

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV6

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: