ISMARA results: ETV7

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ETV7

Z-value: 1.20

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Transcription factors associated with ETV7

Gene Symbol	Gene ID	Gene Info
ETV7 Ensembl NCBI GeneCards UniProt	ENSG00000010030.9	ETS variant transcription factor 7

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ETV7	hg19_v2_chr6_-_36355513_36355578	-0.03	8.9e-01	Click!

Activity profile of ETV7 motif

Sorted Z-values of ETV7 motif

No targets for ETV7

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV7

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	5.3	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2	3.8	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.2	3.5	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.2	3.2	GO:0031167	rRNA methylation(GO:0031167)
0.4	3.1	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.1	3.0	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2	2.7	GO:1902101	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	2.6	GO:0042246	tissue regeneration(GO:0042246)
0.2	1.9	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	1.9	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)

Showing 1 to 10 of 203 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	5.2	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.7	3.7	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.1	3.1	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.0	3.1	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	2.9	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.1	2.7	GO:0005680	anaphase-promoting complex(GO:0005680)
0.2	1.9	GO:0034687	integrin alphaL-beta2 complex(GO:0034687)
0.1	1.7	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	1.6	GO:0005901	caveola(GO:0005901)
0.0	1.5	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)

Showing 1 to 10 of 95 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	6.7	GO:0003735	structural constituent of ribosome(GO:0003735)
0.1	5.3	GO:0005507	copper ion binding(GO:0005507)
0.6	3.4	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1	3.1	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	2.9	GO:0003697	single-stranded DNA binding(GO:0003697)
0.1	2.7	GO:0050786	RAGE receptor binding(GO:0050786)
0.1	2.7	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1	2.0	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2	1.9	GO:0030369	ICAM-3 receptor activity(GO:0030369)
0.0	1.9	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)

Showing 1 to 10 of 152 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.7	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.1	1.7	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.0	1.3	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	1.3	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.0	1.2	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.8	PID EPHA FWDPATHWAY	EPHA forward signaling
0.0	0.7	PID BCR 5PATHWAY	BCR signaling pathway
0.0	0.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.5	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	0.4	PID REELIN PATHWAY	Reelin signaling pathway

Showing 1 to 10 of 15 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	8.1	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	5.4	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	3.5	REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE	Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.1	2.4	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.0	2.3	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	2.2	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	1.9	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.1	1.7	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.1	1.4	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	1.4	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

Showing 1 to 10 of 44 entries

Results for ETV7

Z-value: 1.20

Motif logo

Transcription factors associated with ETV7

Activity-expression correlation:

Activity profile of ETV7 motif

Sorted Z-values of ETV7 motif

No targets for ETV7

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV7

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: