ISMARA results: FOSB

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOSB

Z-value: 1.06

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Transcription factors associated with FOSB

Gene Symbol	Gene ID	Gene Info
FOSB Ensembl NCBI GeneCards UniProt	ENSG00000125740.9	FosB proto-oncogene, AP-1 transcription factor subunit

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOSB	hg19_v2_chr19_+_45971246_45971265	-0.34	1.5e-01	Click!

Activity profile of FOSB motif

Sorted Z-values of FOSB motif

No targets for FOSB

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSB

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.3	GO:0006735	NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2	2.3	GO:0090385	phagosome-lysosome fusion(GO:0090385)
0.0	2.3	GO:0072348	sulfur compound transport(GO:0072348)
0.4	2.0	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0	2.0	GO:0051225	spindle assembly(GO:0051225)
0.1	1.9	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	1.9	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.1	1.7	GO:0070307	lens fiber cell development(GO:0070307)
0.1	1.6	GO:0042908	xenobiotic transport(GO:0042908)
0.0	1.6	GO:0071377	cellular response to glucagon stimulus(GO:0071377)

Showing 1 to 10 of 103 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	2.3	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.2	2.0	GO:0005638	lamin filament(GO:0005638)
0.1	2.0	GO:0070652	HAUS complex(GO:0070652)
0.0	2.0	GO:0042641	actomyosin(GO:0042641)
0.2	1.9	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1	1.7	GO:0005577	fibrinogen complex(GO:0005577)
0.0	1.5	GO:0044291	cell-cell contact zone(GO:0044291)
0.0	1.4	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	1.3	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Showing 1 to 10 of 46 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.1	2.3	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.1	2.3	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	1.9	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	1.9	GO:0017075	syntaxin-1 binding(GO:0017075)
0.4	1.6	GO:0004967	glucagon receptor activity(GO:0004967)
0.1	1.6	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.2	1.5	GO:1990254	keratin filament binding(GO:1990254)
0.2	1.3	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1	1.3	GO:0019957	C-C chemokine binding(GO:0019957)

Showing 1 to 10 of 73 entries

Gene overrepresentation in C2:CP category:

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Total log-likelihood	Term	Description
1.9	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
1.6	PID AURORA B PATHWAY	Aurora B signaling
1.4	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
1.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.8	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.6	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.6	PID TNF PATHWAY	TNF receptor signaling pathway
0.4	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.4	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.4	PID ARF 3PATHWAY	Arf1 pathway

Showing 1 to 10 of 10 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.5	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.1	2.9	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	2.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	2.3	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	2.2	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	1.7	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	1.6	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	1.6	REACTOME GLUCAGON TYPE LIGAND RECEPTORS	Genes involved in Glucagon-type ligand receptors
0.0	1.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	1.4	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines

Showing 1 to 10 of 32 entries

Results for FOSB

Z-value: 1.06

Motif logo

Transcription factors associated with FOSB

Activity-expression correlation:

Activity profile of FOSB motif

Sorted Z-values of FOSB motif

No targets for FOSB

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSB

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: