Project

avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for FOXA1

Z-value: 1.89

Motif logo

Transcription factors associated with FOXA1

Gene Symbol Gene ID Gene Info
ENSG00000129514.4 forkhead box A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA1hg19_v2_chr14_-_38064198_380642390.595.9e-03Click!

Activity profile of FOXA1 motif

Sorted Z-values of FOXA1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.8 3.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.7 5.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.6 1.7 GO:0046521 sphingoid catabolic process(GO:0046521)
0.6 2.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.5 1.9 GO:0060166 olfactory pit development(GO:0060166)
0.5 1.9 GO:0009956 radial pattern formation(GO:0009956)
0.4 2.3 GO:0018032 protein amidation(GO:0018032)
0.4 2.2 GO:0060005 vestibular reflex(GO:0060005)
0.4 8.6 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.3 2.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.3 1.0 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.3 1.0 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.3 1.3 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.3 1.2 GO:1900190 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.3 0.9 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.3 0.9 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.2 1.0 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 1.4 GO:0010193 response to ozone(GO:0010193)
0.2 2.9 GO:0042048 olfactory behavior(GO:0042048)
0.2 3.8 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.2 4.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 1.2 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 2.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 2.0 GO:0021759 globus pallidus development(GO:0021759)
0.1 0.7 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.4 GO:1905069 allantois development(GO:1905069)
0.1 1.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 1.0 GO:1905066 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.1 2.3 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 0.8 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.7 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.3 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.1 0.5 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.1 0.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 0.4 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.1 0.4 GO:0010966 regulation of phosphate transport(GO:0010966)
0.1 0.5 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 1.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 1.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 0.6 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 1.7 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1 1.0 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.7 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.4 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 1.5 GO:0072189 ureter development(GO:0072189)
0.1 1.7 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 1.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 0.4 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.8 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 0.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 2.2 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 1.9 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.1 0.2 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.1 0.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 2.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 1.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.3 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.0 0.3 GO:0060179 male mating behavior(GO:0060179)
0.0 0.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.3 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.2 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.3 GO:0009597 detection of virus(GO:0009597)
0.0 0.4 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.6 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.5 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.2 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 6.4 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 1.4 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0007412 axon target recognition(GO:0007412)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0002870 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.6 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.2 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.2 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:1990357 terminal web(GO:1990357)
0.2 0.9 GO:0035838 growing cell tip(GO:0035838)
0.1 0.8 GO:0031673 H zone(GO:0031673)
0.1 2.9 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 1.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.4 GO:0030478 actin cap(GO:0030478)
0.1 0.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 5.6 GO:0001533 cornified envelope(GO:0001533)
0.1 0.4 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.3 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 4.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.8 GO:0042599 lamellar body(GO:0042599)
0.0 3.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.2 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0 1.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 1.0 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0016013 syntrophin complex(GO:0016013)
0.0 1.2 GO:0043198 dendritic shaft(GO:0043198)
0.0 3.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.8 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.2 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.0 0.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.3 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 1.7 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 0.7 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.2 0.9 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.2 4.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2 0.8 GO:0001855 complement component C4b binding(GO:0001855)
0.2 1.0 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.2 3.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.9 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 1.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.5 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.1 0.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.8 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 1.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 0.2 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 1.2 GO:0005537 mannose binding(GO:0005537)
0.1 0.2 GO:0005046 KDEL sequence binding(GO:0005046)
0.1 0.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 8.5 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 1.0 GO:0000150 recombinase activity(GO:0000150)
0.1 1.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 5.8 GO:0002039 p53 binding(GO:0002039)
0.1 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 1.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.9 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 1.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0004031 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.4 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 4.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 2.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 1.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.6 GO:0015385 sodium:proton antiporter activity(GO:0015385)
0.0 0.3 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.7 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.6 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 2.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.6 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 1.2 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 2.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 1.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.0 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 4.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 5.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 2.0 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.9 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.9 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.1 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 3.2 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 2.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.3 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 0.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.6 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling