ISMARA results: FOXJ2

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXJ2

Z-value: 1.97

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Transcription factors associated with FOXJ2

Gene Symbol	Gene ID	Gene Info
FOXJ2 Ensembl NCBI GeneCards UniProt	ENSG00000065970.4	forkhead box J2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOXJ2	hg19_v2_chr12_+_8185288_8185339	0.73	2.5e-04	Click!

Activity profile of FOXJ2 motif

Sorted Z-values of FOXJ2 motif

No targets for FOXJ2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXJ2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	9.2	GO:0060216	definitive hemopoiesis(GO:0060216)
1.7	8.4	GO:1903282	negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.1	6.0	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.3	5.6	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
1.3	5.1	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.3	4.5	GO:0008090	retrograde axonal transport(GO:0008090)
1.1	4.2	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
0.4	3.9	GO:0003350	pulmonary myocardium development(GO:0003350)
0.0	3.9	GO:0021954	central nervous system neuron development(GO:0021954)
0.6	3.7	GO:0032571	response to vitamin K(GO:0032571) regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) bone regeneration(GO:1990523)

Showing 1 to 10 of 79 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	8.9	GO:0001527	microfibril(GO:0001527) fibril(GO:0043205)
0.2	8.4	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.8	4.5	GO:0031673	H zone(GO:0031673)
0.4	4.2	GO:0097208	alveolar lamellar body(GO:0097208)
0.5	3.9	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
0.1	3.9	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	3.7	GO:0031594	neuromuscular junction(GO:0031594)
0.1	3.3	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.2	3.1	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	3.0	GO:0030315	T-tubule(GO:0030315)

Showing 1 to 10 of 53 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	10.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
1.7	8.4	GO:0060961	phospholipase D inhibitor activity(GO:0060961)
0.2	7.3	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	5.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.2	3.9	GO:0030215	semaphorin receptor binding(GO:0030215)
0.2	3.9	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	3.9	GO:0002162	dystroglycan binding(GO:0002162)
0.0	3.7	GO:0019838	growth factor binding(GO:0019838)
0.9	3.6	GO:0035241	protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0	3.3	GO:0048365	Rac GTPase binding(GO:0048365)

Showing 1 to 10 of 59 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	10.2	PID NOTCH PATHWAY	Notch signaling pathway
0.0	8.8	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	8.1	PID ALPHA SYNUCLEIN PATHWAY	Alpha-synuclein signaling
0.0	4.5	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	4.2	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	3.9	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	3.7	PID LKB1 PATHWAY	LKB1 signaling events
0.0	3.7	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0	2.5	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	2.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.

Showing 1 to 10 of 21 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	11.9	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	4.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	3.9	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.1	3.3	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	3.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.1	2.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	2.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	2.1	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	1.9	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	1.6	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus

Showing 1 to 10 of 31 entries

Results for FOXJ2

Z-value: 1.97

Motif logo

Transcription factors associated with FOXJ2

Activity-expression correlation:

Activity profile of FOXJ2 motif

Sorted Z-values of FOXJ2 motif

No targets for FOXJ2

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXJ2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: