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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXL1

Z-value: 1.80

Motif logo

Transcription factors associated with FOXL1

Gene Symbol Gene ID Gene Info
ENSG00000176678.4 forkhead box L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXL1hg19_v2_chr16_+_86612112_86612123-0.194.2e-01Click!

Activity profile of FOXL1 motif

Sorted Z-values of FOXL1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXL1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
1.5 13.3 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
1.0 3.0 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.8 2.3 GO:0050787 detoxification of mercury ion(GO:0050787)
0.8 4.5 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.7 2.0 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.5 6.6 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.5 2.1 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.5 1.5 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.5 1.5 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.4 1.8 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.4 6.0 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 3.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.4 2.5 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.4 0.7 GO:0014016 neuroblast differentiation(GO:0014016)
0.4 9.2 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.3 2.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.3 1.4 GO:2000230 negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.3 1.7 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.3 14.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.3 0.9 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of auditory receptor cell differentiation(GO:0045608) regulation of timing of neuron differentiation(GO:0060164) common bile duct development(GO:0061009) negative regulation of pro-B cell differentiation(GO:2000974)
0.3 0.9 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.3 0.9 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.3 0.6 GO:0032354 response to follicle-stimulating hormone(GO:0032354) response to gonadotropin(GO:0034698)
0.3 0.8 GO:0030070 insulin processing(GO:0030070)
0.3 1.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.3 1.1 GO:2001248 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.3 1.0 GO:0006601 creatine biosynthetic process(GO:0006601)
0.3 0.8 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.2 0.7 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.2 1.0 GO:0008037 cell recognition(GO:0008037)
0.2 0.7 GO:0015993 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.2 3.6 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.2 0.2 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.2 1.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.2 1.8 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.2 0.2 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 0.6 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 5.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 2.1 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.2 1.0 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.2 0.4 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.2 0.2 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.2 0.4 GO:1902568 regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.2 0.2 GO:0009441 glycolate metabolic process(GO:0009441)
0.2 6.0 GO:0006825 copper ion transport(GO:0006825)
0.2 0.2 GO:0035378 carbon dioxide transmembrane transport(GO:0035378)
0.2 0.5 GO:0051086 chaperone mediated protein folding independent of cofactor(GO:0051086)
0.2 0.5 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.2 0.8 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 1.2 GO:1901523 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.2 1.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.2 0.6 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.2 0.5 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.5 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.2 0.6 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.2 0.6 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.2 0.6 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2 0.9 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.1 0.4 GO:0070408 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1 1.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 1.0 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 1.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.7 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.3 GO:0034390 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 0.6 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.5 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.1 0.7 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.4 GO:0032203 telomere formation via telomerase(GO:0032203)
0.1 1.3 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 0.5 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.1 0.5 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1 0.5 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.8 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 2.1 GO:0030238 male sex determination(GO:0030238)
0.1 0.6 GO:0036512 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.1 0.8 GO:1903899 lung goblet cell differentiation(GO:0060480) positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.7 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.1 0.6 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 2.9 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.5 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 0.5 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.1 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.1 0.3 GO:2000625 rRNA import into mitochondrion(GO:0035928) regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.1 0.5 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.1 2.1 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.1 0.3 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 1.5 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.4 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533)
0.1 1.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 0.7 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 1.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.1 0.4 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 1.1 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.1 0.4 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.6 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.3 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 1.0 GO:0002084 protein depalmitoylation(GO:0002084)
0.1 0.5 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.1 0.5 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.6 GO:0044849 estrous cycle(GO:0044849)
0.1 0.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 0.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0030185 nitric oxide transport(GO:0030185)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 1.5 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.3 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.1 2.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 0.6 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.1 0.2 GO:0071529 cementum mineralization(GO:0071529)
0.1 0.5 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.1 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.3 GO:0032641 lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109)
0.1 1.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 0.8 GO:0046078 dUMP metabolic process(GO:0046078)
0.1 0.2 GO:0034059 response to anoxia(GO:0034059)
0.1 0.4 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.1 GO:0007343 egg activation(GO:0007343)
0.1 0.3 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.1 GO:0038112 interleukin-8-mediated signaling pathway(GO:0038112) response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.1 0.5 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.1 0.3 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.1 0.1 GO:0019724 B cell mediated immunity(GO:0019724)
0.1 2.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.4 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.1 0.3 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 0.5 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.5 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 1.5 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.2 GO:0034130 toll-like receptor 1 signaling pathway(GO:0034130)
0.1 0.3 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.3 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.5 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 1.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 1.6 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.7 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.3 GO:0019566 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.1 0.9 GO:0071941 urea metabolic process(GO:0019627) nitrogen cycle metabolic process(GO:0071941)
0.1 1.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0048738 cardiac muscle tissue development(GO:0048738)
0.1 1.6 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.1 0.6 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.6 GO:2000334 blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.1 5.4 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 1.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.2 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.1 1.3 GO:0031167 rRNA methylation(GO:0031167)
0.0 1.2 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 1.8 GO:0010447 response to acidic pH(GO:0010447)
0.0 0.1 GO:0042214 terpene metabolic process(GO:0042214)
0.0 0.5 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.3 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0046968 peptide antigen transport(GO:0046968)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678) swimming behavior(GO:0036269)
0.0 0.4 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0048749 compound eye development(GO:0048749)
0.0 0.1 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.1 GO:0035038 female pronucleus assembly(GO:0035038)
0.0 0.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.2 GO:0046070 dGTP catabolic process(GO:0006203) dGTP metabolic process(GO:0046070)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 1.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0061046 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492) regulation of branching involved in lung morphogenesis(GO:0061046) positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.0 0.2 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.2 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.0 0.2 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.6 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.5 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.5 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.3 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.4 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.4 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.3 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.6 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.1 GO:0002065 columnar/cuboidal epithelial cell differentiation(GO:0002065)
0.0 0.2 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.3 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.5 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.3 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.2 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 1.1 GO:0051923 sulfation(GO:0051923)
0.0 0.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.6 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.4 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:0033383 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 0.4 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.3 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 1.1 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0052053 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0002885 positive regulation of type I hypersensitivity(GO:0001812) positive regulation of hypersensitivity(GO:0002885)
0.0 0.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 1.3 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.3 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.4 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.2 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.0 0.0 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.9 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:2000521 natural killer cell tolerance induction(GO:0002519) negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859) regulation of immunological synapse formation(GO:2000520) negative regulation of immunological synapse formation(GO:2000521)
0.0 0.1 GO:0034473 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) U1 snRNA 3'-end processing(GO:0034473) U4 snRNA 3'-end processing(GO:0034475) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.6 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.1 GO:1903719 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 1.0 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.4 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.0 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 1.3 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.1 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.5 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.3 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.4 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.6 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 1.0 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.1 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.0 0.3 GO:0030239 myofibril assembly(GO:0030239)
0.0 1.5 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.2 GO:0033604 negative regulation of catecholamine secretion(GO:0033604)
0.0 0.8 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0043102 amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.0 2.5 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.5 GO:0006855 drug transmembrane transport(GO:0006855)
0.0 0.3 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.7 GO:0035640 exploration behavior(GO:0035640)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 1.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.8 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.0 0.2 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.3 GO:0002467 germinal center formation(GO:0002467)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 0.3 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 1.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.0 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795) negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.0 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416) regulation of cholesterol transporter activity(GO:0060694)
0.0 0.4 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:0030038 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.2 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.2 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.0 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.0 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.8 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.1 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.0 0.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.5 GO:0006505 GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.5 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.3 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.4 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.1 GO:0060591 ossification involved in bone remodeling(GO:0043932) chondroblast differentiation(GO:0060591)
0.0 0.6 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.0 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.2 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.1 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0051552 flavone metabolic process(GO:0051552)
0.0 1.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:0050974 detection of mechanical stimulus involved in sensory perception(GO:0050974)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.1 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.4 6.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 1.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.2 1.7 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 1.5 GO:0036021 endolysosome lumen(GO:0036021)
0.2 0.6 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.8 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.2 4.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.2 1.0 GO:1990246 uniplex complex(GO:1990246)
0.2 2.2 GO:0042788 polysomal ribosome(GO:0042788)
0.2 1.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 0.5 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.7 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 1.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 1.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.5 GO:0097149 centralspindlin complex(GO:0097149)
0.1 1.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.4 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.8 GO:0036128 CatSper complex(GO:0036128)
0.1 0.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.1 1.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.1 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.7 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 1.1 GO:0032300 mismatch repair complex(GO:0032300)
0.1 1.2 GO:0033010 paranodal junction(GO:0033010)
0.1 0.6 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 1.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 0.6 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.6 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 4.6 GO:0031941 filamentous actin(GO:0031941)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.2 GO:1990423 RZZ complex(GO:1990423)
0.1 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.5 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.8 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0032127 dense core granule membrane(GO:0032127) microvesicle(GO:1990742)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.6 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 2.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.5 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.9 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 3.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.3 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 5.6 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.7 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 0.5 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.0 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.6 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 1.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.8 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.8 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.0 0.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 2.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0031091 platelet alpha granule(GO:0031091)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0036398 TCR signalosome(GO:0036398)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 7.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.0 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 1.0 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.6 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.9 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.2 GO:0016605 PML body(GO:0016605)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.3 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.0 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.2 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.0 GO:0048269 methionine adenosyltransferase complex(GO:0048269)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 6.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.3 1.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
1.0 3.0 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.6 3.2 GO:0047086 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.5 2.1 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.5 2.6 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.5 13.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.5 1.4 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.5 5.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 3.3 GO:0005132 type I interferon receptor binding(GO:0005132)
0.4 1.7 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.4 1.2 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.4 1.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.3 1.0 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.3 4.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 1.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.3 10.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.3 2.5 GO:1990932 5.8S rRNA binding(GO:1990932)
0.3 1.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3 1.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.3 1.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.3 0.8 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2 0.7 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.2 2.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 1.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.2 0.6 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.2 0.6 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.2 0.7 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.2 1.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.2 0.7 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 0.5 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.2 2.1 GO:0003796 lysozyme activity(GO:0003796)
0.2 0.5 GO:0031177 phosphopantetheine binding(GO:0031177)
0.2 2.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.2 1.4 GO:0050692 DBD domain binding(GO:0050692)
0.2 0.6 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.2 0.5 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.2 1.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.7 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 0.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.7 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 1.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.4 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.7 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.1 2.0 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.4 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 1.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 3.7 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 0.7 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.1 0.4 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0008124 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.1 0.6 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 1.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.3 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.3 GO:0030984 kininogen binding(GO:0030984)
0.1 0.7 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.3 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.1 0.3 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.3 GO:0001601 peptide YY receptor activity(GO:0001601)
0.1 1.0 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.2 GO:0004531 deoxyribonuclease II activity(GO:0004531)
0.1 0.4 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.5 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.1 0.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 0.3 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.1 0.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.0 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.8 GO:0000217 DNA secondary structure binding(GO:0000217)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.5 GO:0004447 iodide peroxidase activity(GO:0004447)
0.1 0.2 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.1 0.4 GO:0003998 acylphosphatase activity(GO:0003998)
0.1 0.7 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.5 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.3 GO:0030492 hemoglobin binding(GO:0030492)
0.1 1.6 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.6 GO:0043394 proteoglycan binding(GO:0043394)
0.1 0.3 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.1 0.3 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.3 GO:0031208 POZ domain binding(GO:0031208)
0.1 1.1 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.2 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.2 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.1 1.0 GO:0005549 odorant binding(GO:0005549)
0.1 0.8 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 0.6 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 2.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.1 1.5 GO:0008301 DNA binding, bending(GO:0008301)
0.1 0.2 GO:0097604 temperature-gated cation channel activity(GO:0097604)
0.1 0.7 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.4 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 4.4 GO:0004984 olfactory receptor activity(GO:0004984)
0.1 1.4 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 1.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.9 GO:0051400 BH domain binding(GO:0051400)
0.0 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 3.7 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 7.1 GO:0051087 chaperone binding(GO:0051087)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.5 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.5 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 1.1 GO:0008009 chemokine activity(GO:0008009)
0.0 0.3 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 2.5 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 2.6 GO:0005507 copper ion binding(GO:0005507)
0.0 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0031013 troponin I binding(GO:0031013)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.5 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.1 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.3 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0008048 calcium sensitive guanylate cyclase activator activity(GO:0008048)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.5 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.7 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.0 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.3 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 2.0 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.2 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 1.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.5 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.3 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 5.7 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0004918 interleukin-8 receptor activity(GO:0004918)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.0 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.0 0.1 GO:0019144 ADP-sugar diphosphatase activity(GO:0019144)
0.0 2.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 10.1 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 1.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 4.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 0.5 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 0.2 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 0.7 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.6 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 1.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 2.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 2.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.4 PID ATM PATHWAY ATM pathway
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 1.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 4.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.5 9.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 0.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 3.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 6.7 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 2.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 4.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 3.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 1.0 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 1.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 1.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.9 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 2.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 3.5 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 2.6 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.4 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 1.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.1 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 2.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME GABA B RECEPTOR ACTIVATION Genes involved in GABA B receptor activation
0.0 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.5 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.2 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.0 0.6 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.1 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.7 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 0.4 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.6 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins