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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXN1

Z-value: 1.83

Motif logo

Transcription factors associated with FOXN1

Gene Symbol Gene ID Gene Info
ENSG00000109101.3 forkhead box N1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXN1hg19_v2_chr17_+_26833250_26833278-0.243.1e-01Click!

Activity profile of FOXN1 motif

Sorted Z-values of FOXN1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXN1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0019303 D-ribose catabolic process(GO:0019303)
0.5 3.1 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.5 4.8 GO:0045218 zonula adherens maintenance(GO:0045218)
0.5 1.4 GO:0099558 maintenance of synapse structure(GO:0099558)
0.5 2.3 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.4 4.5 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.4 1.1 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.4 1.1 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.4 1.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.4 3.2 GO:0030242 pexophagy(GO:0030242)
0.3 2.0 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.3 2.3 GO:0046208 spermine catabolic process(GO:0046208)
0.3 1.1 GO:0014060 regulation of epinephrine secretion(GO:0014060) negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625) epinephrine secretion(GO:0048242)
0.2 0.7 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.2 1.8 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 0.8 GO:0031392 regulation of prostaglandin biosynthetic process(GO:0031392) regulation of unsaturated fatty acid biosynthetic process(GO:2001279)
0.2 0.8 GO:0072302 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
0.2 2.0 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.2 1.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.2 0.6 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.2 0.7 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.2 1.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 0.5 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.4 GO:0021793 chemorepulsion of branchiomotor axon(GO:0021793)
0.1 0.9 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 3.0 GO:0071318 cellular response to ATP(GO:0071318)
0.1 1.1 GO:0010159 specification of organ position(GO:0010159) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 1.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 1.0 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.4 GO:0006106 fumarate metabolic process(GO:0006106)
0.1 1.0 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.9 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.1 0.7 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.1 0.8 GO:0035865 cellular response to potassium ion(GO:0035865)
0.1 0.9 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 1.7 GO:0002158 osteoclast proliferation(GO:0002158)
0.1 1.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.7 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.6 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.6 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.3 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.3 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.1 0.3 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 1.0 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.2 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.1 1.3 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.6 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.5 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 1.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.1 1.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.4 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 1.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.9 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.5 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 0.9 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.4 GO:0061074 regulation of neural retina development(GO:0061074) negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.3 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.6 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.3 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.8 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.4 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.1 0.7 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 1.9 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 1.0 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 1.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.6 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:0060018 positive regulation of chromatin assembly or disassembly(GO:0045799) astrocyte fate commitment(GO:0060018)
0.0 0.7 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 1.9 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0006844 acyl carnitine transport(GO:0006844) acyl carnitine transmembrane transport(GO:1902616)
0.0 0.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.0 0.7 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.0 0.4 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 1.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.7 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.9 GO:0033260 nuclear DNA replication(GO:0033260)
0.0 0.5 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 1.9 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.3 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.8 GO:0006004 fucose metabolic process(GO:0006004)
0.0 1.4 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.8 GO:0045019 negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 1.5 GO:0097120 receptor localization to synapse(GO:0097120)
0.0 0.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.2 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.6 GO:0030335 positive regulation of cell migration(GO:0030335)
0.0 0.6 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.0 0.1 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 1.7 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.5 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.8 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.8 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.2 GO:0010748 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 3.1 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.5 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.9 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.5 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549)
0.0 0.8 GO:0043276 anoikis(GO:0043276)
0.0 0.1 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 0.3 GO:0044804 nucleophagy(GO:0044804)
0.0 0.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.0 GO:0005927 muscle tendon junction(GO:0005927)
0.4 1.4 GO:0044301 climbing fiber(GO:0044301)
0.3 1.2 GO:0044753 amphisome(GO:0044753)
0.2 0.6 GO:0008623 CHRAC(GO:0008623)
0.2 4.8 GO:0005915 zonula adherens(GO:0005915)
0.1 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.1 GO:0016589 NURF complex(GO:0016589)
0.1 0.9 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.7 GO:0043196 varicosity(GO:0043196)
0.1 0.2 GO:0039713 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.1 0.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.8 GO:0000178 exosome (RNase complex)(GO:0000178)
0.1 0.6 GO:0070852 cell body fiber(GO:0070852)
0.1 0.5 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 0.9 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.3 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 2.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.9 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.0 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 1.0 GO:0036020 endolysosome membrane(GO:0036020)
0.0 2.1 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 3.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.9 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 3.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 3.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.7 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 3.1 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 1.2 GO:1904724 specific granule lumen(GO:0035580) tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.6 GO:0016592 mediator complex(GO:0016592)
0.0 1.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0052894 norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895)
0.6 2.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.5 3.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.5 1.9 GO:0032427 GBD domain binding(GO:0032427)
0.4 1.1 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.3 2.0 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 0.8 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.3 0.8 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.1 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.2 1.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 2.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.2 0.8 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.2 0.8 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.2 0.5 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 1.0 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 4.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 0.4 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 4.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.8 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.5 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.4 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.9 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.7 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 3.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 1.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.7 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.8 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.1 4.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.1 0.9 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 1.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 1.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.2 GO:0015227 acyl carnitine transmembrane transporter activity(GO:0015227)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 1.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.8 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.9 GO:0016805 dipeptidase activity(GO:0016805)
0.0 1.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.3 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.0 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 1.2 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 1.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 3.0 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.6 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 0.2 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 2.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 3.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.9 PID INSULIN PATHWAY Insulin Pathway
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.7 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.1 4.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 4.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 1.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.1 1.2 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 3.1 REACTOME KINESINS Genes involved in Kinesins
0.1 0.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.9 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 3.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 1.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 1.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.9 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 2.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.7 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.9 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.7 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.0 0.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex