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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for GATA1_GATA4
Z-value: 1.29
Motif logo
Transcription factors associated with GATA1_GATA4
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
GATA1
|
ENSG00000102145.9 | GATA binding protein 1 |
|
GATA4
|
ENSG00000136574.13 | GATA binding protein 4 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GATA4 | hg19_v2_chr8_+_11534462_11534475 | -0.84 | 4.1e-06 | Click! |
| GATA1 | hg19_v2_chrX_+_48644962_48644983 | 0.05 | 8.4e-01 | Click! |
Activity profile of GATA1_GATA4 motif
Sorted Z-values of GATA1_GATA4 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of GATA1_GATA4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 3.9 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 0.8 | 3.3 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 0.8 | 5.3 | GO:0002786 | regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) |
| 0.6 | 6.6 | GO:0072656 | maintenance of protein location in mitochondrion(GO:0072656) |
| 0.5 | 1.5 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
| 0.4 | 2.2 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.4 | 2.5 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.4 | 2.0 | GO:0032474 | otolith morphogenesis(GO:0032474) |
| 0.4 | 1.5 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 0.4 | 2.5 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.3 | 1.6 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.3 | 1.2 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 0.3 | 1.1 | GO:0048936 | visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258) |
| 0.3 | 2.0 | GO:0097461 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.2 | 0.7 | GO:0032747 | positive regulation of interleukin-23 production(GO:0032747) |
| 0.2 | 0.7 | GO:1902732 | positive regulation of chondrocyte proliferation(GO:1902732) |
| 0.2 | 1.7 | GO:0071461 | cellular response to redox state(GO:0071461) |
| 0.2 | 1.4 | GO:0060437 | lung growth(GO:0060437) |
| 0.2 | 1.1 | GO:0071477 | hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477) |
| 0.2 | 0.7 | GO:0031247 | actin rod assembly(GO:0031247) |
| 0.2 | 1.3 | GO:0051673 | membrane disruption in other organism(GO:0051673) |
| 0.2 | 0.8 | GO:0001828 | inner cell mass cellular morphogenesis(GO:0001828) |
| 0.2 | 1.0 | GO:0002317 | plasma cell differentiation(GO:0002317) |
| 0.2 | 0.7 | GO:0060448 | dichotomous subdivision of terminal units involved in lung branching(GO:0060448) |
| 0.2 | 0.5 | GO:0048633 | negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.2 | 2.2 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 0.1 | 0.9 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 0.1 | 1.7 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
| 0.1 | 0.4 | GO:2000742 | anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744) |
| 0.1 | 1.4 | GO:1903764 | regulation of potassium ion export across plasma membrane(GO:1903764) |
| 0.1 | 0.6 | GO:0071344 | diphosphate metabolic process(GO:0071344) |
| 0.1 | 0.5 | GO:0051413 | response to cortisone(GO:0051413) |
| 0.1 | 0.4 | GO:1904719 | excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
| 0.1 | 0.6 | GO:0070317 | negative regulation of G0 to G1 transition(GO:0070317) |
| 0.1 | 4.2 | GO:0060644 | mammary gland epithelial cell differentiation(GO:0060644) |
| 0.1 | 0.2 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.1 | 0.6 | GO:0030311 | poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 0.1 | 0.5 | GO:0010593 | negative regulation of lamellipodium assembly(GO:0010593) |
| 0.1 | 0.2 | GO:0007493 | endodermal cell fate determination(GO:0007493) |
| 0.1 | 0.6 | GO:0038098 | sequestering of BMP from receptor via BMP binding(GO:0038098) |
| 0.1 | 1.3 | GO:0006657 | CDP-choline pathway(GO:0006657) |
| 0.1 | 1.6 | GO:0070970 | interleukin-2 secretion(GO:0070970) |
| 0.1 | 0.8 | GO:1900425 | negative regulation of defense response to bacterium(GO:1900425) |
| 0.1 | 0.7 | GO:2000670 | positive regulation of dendritic cell apoptotic process(GO:2000670) |
| 0.1 | 0.8 | GO:1902730 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 0.1 | 0.3 | GO:1904000 | positive regulation of growth rate(GO:0040010) positive regulation of eating behavior(GO:1904000) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768) |
| 0.1 | 0.7 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.1 | 0.4 | GO:2000097 | negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.1 | 2.1 | GO:0071481 | cellular response to X-ray(GO:0071481) |
| 0.1 | 0.6 | GO:0071955 | recycling endosome to Golgi transport(GO:0071955) |
| 0.1 | 0.6 | GO:0006196 | AMP catabolic process(GO:0006196) |
| 0.1 | 0.3 | GO:1904875 | regulation of DNA ligase activity(GO:1904875) |
| 0.1 | 0.8 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.1 | 1.0 | GO:0035986 | senescence-associated heterochromatin focus assembly(GO:0035986) |
| 0.1 | 0.3 | GO:2000502 | negative regulation of natural killer cell chemotaxis(GO:2000502) |
| 0.1 | 0.4 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
| 0.1 | 0.5 | GO:1904217 | regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222) |
| 0.1 | 0.4 | GO:1905167 | positive regulation of lysosomal protein catabolic process(GO:1905167) |
| 0.1 | 1.2 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 0.1 | 1.1 | GO:0060613 | fat pad development(GO:0060613) |
| 0.1 | 1.1 | GO:0010499 | proteasomal ubiquitin-independent protein catabolic process(GO:0010499) |
| 0.1 | 0.4 | GO:1900827 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.1 | 0.2 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 0.1 | 2.4 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.1 | 0.7 | GO:0071847 | TNFSF11-mediated signaling pathway(GO:0071847) |
| 0.1 | 1.7 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.1 | 0.2 | GO:0061485 | memory T cell proliferation(GO:0061485) |
| 0.1 | 0.3 | GO:0036378 | calcitriol biosynthetic process from calciol(GO:0036378) |
| 0.1 | 0.7 | GO:0009449 | gamma-aminobutyric acid biosynthetic process(GO:0009449) |
| 0.1 | 0.2 | GO:0070781 | arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781) |
| 0.1 | 0.4 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.1 | 0.4 | GO:2001288 | positive regulation of caveolin-mediated endocytosis(GO:2001288) |
| 0.1 | 2.0 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.1 | 0.6 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.1 | 0.4 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 0.1 | 2.2 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 0.2 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
| 0.1 | 0.3 | GO:0033088 | negative regulation of immature T cell proliferation in thymus(GO:0033088) |
| 0.1 | 0.6 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
| 0.1 | 0.2 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.1 | 0.2 | GO:0098884 | postsynaptic neurotransmitter receptor internalization(GO:0098884) |
| 0.1 | 0.2 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 0.1 | 0.4 | GO:1902164 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
| 0.1 | 0.8 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 0.1 | 2.8 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.1 | 0.2 | GO:0016094 | polyprenol biosynthetic process(GO:0016094) |
| 0.1 | 0.7 | GO:0021702 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.1 | 0.5 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
| 0.1 | 0.3 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.1 | 3.1 | GO:0032731 | positive regulation of interleukin-1 beta production(GO:0032731) |
| 0.1 | 0.7 | GO:0060235 | lens induction in camera-type eye(GO:0060235) |
| 0.1 | 0.2 | GO:0021827 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
| 0.0 | 0.1 | GO:1902613 | regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) |
| 0.0 | 0.4 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.0 | 0.8 | GO:0060056 | mammary gland involution(GO:0060056) |
| 0.0 | 1.1 | GO:1900103 | positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103) |
| 0.0 | 0.4 | GO:0003025 | regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564) |
| 0.0 | 1.2 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 0.0 | 1.3 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.0 | 0.5 | GO:0045950 | negative regulation of mitotic recombination(GO:0045950) |
| 0.0 | 0.9 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.0 | 0.3 | GO:0006789 | bilirubin conjugation(GO:0006789) |
| 0.0 | 2.7 | GO:0046329 | negative regulation of JNK cascade(GO:0046329) |
| 0.0 | 0.1 | GO:0042270 | protection from natural killer cell mediated cytotoxicity(GO:0042270) |
| 0.0 | 0.1 | GO:0030327 | prenylated protein catabolic process(GO:0030327) |
| 0.0 | 0.4 | GO:0072189 | ureter development(GO:0072189) |
| 0.0 | 0.5 | GO:0036500 | ATF6-mediated unfolded protein response(GO:0036500) |
| 0.0 | 0.2 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.0 | 0.4 | GO:0007288 | sperm axoneme assembly(GO:0007288) |
| 0.0 | 0.3 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.0 | 0.3 | GO:0097428 | protein maturation by iron-sulfur cluster transfer(GO:0097428) |
| 0.0 | 0.4 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.0 | 0.1 | GO:1902769 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 0.0 | 0.7 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.7 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.0 | 0.4 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.0 | 1.1 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.0 | 0.4 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.0 | 2.8 | GO:0048488 | synaptic vesicle endocytosis(GO:0048488) |
| 0.0 | 0.4 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 0.0 | 0.2 | GO:1902269 | positive regulation of polyamine transmembrane transport(GO:1902269) |
| 0.0 | 3.0 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.0 | 0.9 | GO:0003298 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.3 | GO:2001206 | positive regulation of osteoclast development(GO:2001206) |
| 0.0 | 0.1 | GO:0018879 | biphenyl metabolic process(GO:0018879) |
| 0.0 | 1.1 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.0 | 0.2 | GO:0044778 | meiotic DNA integrity checkpoint(GO:0044778) |
| 0.0 | 1.1 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
| 0.0 | 0.1 | GO:0070602 | regulation of centromeric sister chromatid cohesion(GO:0070602) |
| 0.0 | 9.2 | GO:0007173 | epidermal growth factor receptor signaling pathway(GO:0007173) |
| 0.0 | 0.5 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 0.5 | GO:0098814 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.0 | 0.4 | GO:0097475 | motor neuron migration(GO:0097475) |
| 0.0 | 0.6 | GO:0001946 | lymphangiogenesis(GO:0001946) |
| 0.0 | 1.2 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.0 | 0.1 | GO:0021849 | neuroblast division in subventricular zone(GO:0021849) |
| 0.0 | 1.2 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 1.3 | GO:2000178 | negative regulation of neural precursor cell proliferation(GO:2000178) |
| 0.0 | 0.5 | GO:0048227 | plasma membrane to endosome transport(GO:0048227) |
| 0.0 | 0.3 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
| 0.0 | 0.2 | GO:0061055 | myotome development(GO:0061055) |
| 0.0 | 1.1 | GO:0048305 | immunoglobulin secretion(GO:0048305) |
| 0.0 | 3.4 | GO:0009301 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.0 | 0.1 | GO:0018874 | benzoate metabolic process(GO:0018874) |
| 0.0 | 0.2 | GO:0060215 | primitive hemopoiesis(GO:0060215) |
| 0.0 | 0.4 | GO:0090235 | regulation of metaphase plate congression(GO:0090235) |
| 0.0 | 0.2 | GO:0060686 | negative regulation of prostatic bud formation(GO:0060686) |
| 0.0 | 0.2 | GO:0072752 | cellular response to rapamycin(GO:0072752) |
| 0.0 | 0.7 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.0 | 0.1 | GO:0060708 | spongiotrophoblast differentiation(GO:0060708) |
| 0.0 | 1.0 | GO:0014037 | Schwann cell differentiation(GO:0014037) |
| 0.0 | 0.3 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.0 | 0.4 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.0 | 1.0 | GO:0043090 | amino acid import(GO:0043090) |
| 0.0 | 1.4 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.0 | 0.2 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.0 | 0.2 | GO:0009744 | response to sucrose(GO:0009744) response to disaccharide(GO:0034285) |
| 0.0 | 0.4 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 0.0 | 0.3 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.0 | 0.2 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.0 | 0.4 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
| 0.0 | 0.3 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.0 | 0.5 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.0 | 0.2 | GO:0071895 | odontoblast differentiation(GO:0071895) |
| 0.0 | 0.2 | GO:1902774 | late endosome to lysosome transport(GO:1902774) |
| 0.0 | 0.7 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.0 | 0.1 | GO:0090611 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 0.0 | 0.2 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
| 0.0 | 0.4 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.0 | 0.9 | GO:0061003 | positive regulation of dendritic spine morphogenesis(GO:0061003) |
| 0.0 | 0.1 | GO:0010166 | wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166) |
| 0.0 | 0.2 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.0 | 0.4 | GO:0043086 | negative regulation of catalytic activity(GO:0043086) |
| 0.0 | 0.1 | GO:0090234 | regulation of kinetochore assembly(GO:0090234) |
| 0.0 | 0.3 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.0 | 0.1 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 0.0 | 0.1 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.0 | 0.1 | GO:1902262 | apoptotic process involved in patterning of blood vessels(GO:1902262) |
| 0.0 | 0.5 | GO:0043518 | negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518) |
| 0.0 | 0.3 | GO:0045048 | protein insertion into ER membrane(GO:0045048) |
| 0.0 | 0.1 | GO:0093001 | glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001) |
| 0.0 | 0.1 | GO:0015808 | L-alanine transport(GO:0015808) |
| 0.0 | 0.2 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.0 | 0.3 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.3 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
| 0.0 | 0.2 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.0 | 0.3 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.0 | 0.1 | GO:0021778 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.0 | 0.2 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
| 0.0 | 0.9 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 0.0 | 0.1 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.0 | 0.0 | GO:1903215 | negative regulation of protein targeting to mitochondrion(GO:1903215) |
| 0.0 | 0.1 | GO:1902310 | positive regulation of peptidyl-serine dephosphorylation(GO:1902310) |
| 0.0 | 0.7 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.2 | GO:0035826 | rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680) |
| 0.0 | 0.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.0 | 0.1 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 0.0 | 1.6 | GO:0007049 | cell cycle(GO:0007049) |
| 0.0 | 0.1 | GO:0052696 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.0 | 1.6 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.0 | 0.1 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.0 | 0.0 | GO:0032713 | negative regulation of interleukin-4 production(GO:0032713) |
| 0.0 | 0.7 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 0.2 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.0 | 0.8 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
| 0.0 | 0.2 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.0 | 0.2 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 0.0 | 0.1 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.0 | 0.1 | GO:0002316 | follicular B cell differentiation(GO:0002316) |
| 0.0 | 0.1 | GO:0034312 | diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512) |
| 0.0 | 0.0 | GO:0036269 | swimming behavior(GO:0036269) |
| 0.0 | 0.2 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.0 | 0.2 | GO:0045657 | positive regulation of monocyte differentiation(GO:0045657) |
| 0.0 | 0.2 | GO:0051607 | defense response to virus(GO:0051607) |
| 0.0 | 0.2 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.0 | 0.1 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.0 | 0.2 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.0 | 0.2 | GO:2000766 | negative regulation of cytoplasmic translation(GO:2000766) |
| 0.0 | 0.3 | GO:0051290 | protein heterotetramerization(GO:0051290) |
| 0.0 | 0.1 | GO:0002643 | regulation of tolerance induction(GO:0002643) |
| 0.0 | 0.1 | GO:0072221 | distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) |
| 0.0 | 0.8 | GO:0002223 | stimulatory C-type lectin receptor signaling pathway(GO:0002223) |
| 0.0 | 0.1 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 0.0 | 0.6 | GO:0003382 | epithelial cell morphogenesis(GO:0003382) |
| 0.0 | 0.2 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 1.1 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 1.1 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 0.1 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 0.0 | 1.2 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.0 | 0.5 | GO:0016577 | histone demethylation(GO:0016577) |
| 0.0 | 0.3 | GO:0007184 | SMAD protein import into nucleus(GO:0007184) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 5.3 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 0.5 | 1.9 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.4 | 3.4 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.3 | 2.1 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 0.2 | 2.2 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.2 | 6.8 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 1.1 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.1 | 1.4 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.1 | 1.6 | GO:0012505 | endomembrane system(GO:0012505) |
| 0.1 | 0.8 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.1 | 0.1 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.1 | 1.4 | GO:0097025 | lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.1 | 1.0 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.1 | 0.4 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
| 0.1 | 0.9 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.1 | 1.9 | GO:0005922 | connexon complex(GO:0005922) |
| 0.1 | 0.1 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 0.7 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.1 | 0.7 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.1 | 0.2 | GO:0098844 | postsynaptic endocytic zone membrane(GO:0098844) |
| 0.1 | 0.3 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 0.1 | 0.3 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.1 | 3.9 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.0 | 1.9 | GO:0031105 | septin complex(GO:0031105) |
| 0.0 | 0.6 | GO:0030057 | desmosome(GO:0030057) |
| 0.0 | 0.6 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.0 | 0.5 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 0.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.0 | 0.1 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
| 0.0 | 1.8 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 0.7 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.0 | 2.7 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 0.4 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 5.1 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.7 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 0.1 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.0 | 0.4 | GO:0071986 | Ragulator complex(GO:0071986) |
| 0.0 | 0.5 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 0.2 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.0 | 0.3 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.0 | 0.4 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 0.6 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 1.6 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.8 | GO:0071011 | precatalytic spliceosome(GO:0071011) |
| 0.0 | 0.4 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 0.3 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.0 | 0.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.2 | GO:0055028 | cortical microtubule(GO:0055028) |
| 0.0 | 0.0 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.0 | 3.5 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 0.2 | GO:0097413 | Lewy body(GO:0097413) |
| 0.0 | 0.4 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.2 | GO:0000347 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.0 | 0.2 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.0 | 0.2 | GO:0002177 | manchette(GO:0002177) |
| 0.0 | 2.2 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 0.2 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.0 | 0.2 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 0.3 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.0 | 1.5 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 0.1 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.0 | 0.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.5 | GO:0033268 | node of Ranvier(GO:0033268) |
| 0.0 | 0.2 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.0 | 1.0 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.0 | GO:1990716 | axonemal central apparatus(GO:1990716) |
| 0.0 | 2.6 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.1 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.0 | 0.1 | GO:0030061 | mitochondrial crista(GO:0030061) |
| 0.0 | 3.3 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 1.5 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.4 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.3 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.0 | 0.3 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.7 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 1.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.1 | GO:1990246 | uniplex complex(GO:1990246) |
| 0.0 | 1.0 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.8 | GO:0016235 | aggresome(GO:0016235) |
| 0.0 | 0.8 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 0.2 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.0 | 0.4 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.0 | 0.0 | GO:0036025 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 0.0 | 1.1 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 0.2 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 0.1 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.8 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.2 | GO:0031672 | A band(GO:0031672) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.5 | GO:0002113 | interleukin-33 binding(GO:0002113) |
| 0.7 | 2.2 | GO:0036313 | phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313) |
| 0.7 | 6.4 | GO:0004396 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.5 | 1.5 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 0.5 | 9.9 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.4 | 1.7 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644) |
| 0.3 | 0.9 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 0.3 | 2.0 | GO:0008823 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 0.3 | 1.3 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
| 0.3 | 2.0 | GO:0045118 | azole transporter activity(GO:0045118) |
| 0.2 | 3.9 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.2 | 1.3 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
| 0.2 | 1.5 | GO:0008481 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
| 0.2 | 1.9 | GO:0019798 | procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798) |
| 0.2 | 0.8 | GO:0032184 | SUMO polymer binding(GO:0032184) |
| 0.1 | 1.7 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.1 | 0.7 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 0.1 | 0.4 | GO:0016964 | alpha-2 macroglobulin receptor activity(GO:0016964) |
| 0.1 | 3.9 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 1.7 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.1 | 0.3 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.1 | 1.4 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.1 | 0.6 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.1 | 0.6 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.1 | 0.3 | GO:0031768 | growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768) |
| 0.1 | 1.9 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 0.7 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.1 | 0.6 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.1 | 1.1 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.1 | 0.8 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 0.1 | 0.3 | GO:1902271 | D3 vitamins binding(GO:1902271) |
| 0.1 | 0.3 | GO:0030343 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
| 0.1 | 3.3 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.1 | 1.3 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.1 | 3.4 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 1.6 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.1 | 0.2 | GO:1904854 | proteasome core complex binding(GO:1904854) |
| 0.1 | 0.3 | GO:0010348 | lithium:proton antiporter activity(GO:0010348) |
| 0.1 | 0.7 | GO:0046790 | virion binding(GO:0046790) |
| 0.1 | 1.0 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.1 | 1.1 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.1 | 0.7 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 0.6 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.1 | 0.5 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.1 | 0.5 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
| 0.1 | 0.6 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.2 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) |
| 0.1 | 0.4 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.1 | 1.7 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.1 | 0.2 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.1 | 0.6 | GO:0016015 | morphogen activity(GO:0016015) |
| 0.0 | 0.4 | GO:0003846 | 2-acylglycerol O-acyltransferase activity(GO:0003846) |
| 0.0 | 1.1 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 0.2 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) |
| 0.0 | 0.3 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.0 | 0.5 | GO:0004305 | ethanolamine kinase activity(GO:0004305) |
| 0.0 | 0.5 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.0 | 0.4 | GO:0030250 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 0.0 | 0.6 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.0 | 0.9 | GO:0042301 | phosphate ion binding(GO:0042301) |
| 0.0 | 0.2 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.0 | 0.3 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.0 | 0.3 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.0 | 5.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.3 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.0 | 1.2 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.0 | 1.2 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.0 | 9.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 0.8 | GO:0070016 | gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016) |
| 0.0 | 0.1 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 0.0 | 0.5 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 0.2 | GO:0047756 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin 4-sulfotransferase activity(GO:0047756) |
| 0.0 | 0.3 | GO:0004849 | uridine kinase activity(GO:0004849) |
| 0.0 | 0.7 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 0.7 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.0 | 0.4 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.0 | 0.1 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.0 | 0.3 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
| 0.0 | 0.2 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.0 | 0.2 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 0.0 | 0.1 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.0 | 0.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.2 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 1.7 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.0 | 0.5 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 0.1 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.0 | 0.6 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.1 | GO:0080019 | fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019) |
| 0.0 | 1.3 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 0.1 | GO:0015180 | L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858) |
| 0.0 | 0.1 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.0 | 0.2 | GO:0042978 | ornithine decarboxylase activator activity(GO:0042978) |
| 0.0 | 0.2 | GO:0070139 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
| 0.0 | 3.6 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 1.3 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.0 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 0.0 | 0.8 | GO:0004385 | guanylate kinase activity(GO:0004385) |
| 0.0 | 0.2 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.0 | 12.1 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.0 | 0.8 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.7 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.4 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.0 | 0.9 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.8 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 0.2 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 0.4 | GO:0070008 | serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008) |
| 0.0 | 0.2 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.0 | 0.4 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.0 | 0.3 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.0 | 0.1 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 1.7 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.4 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.2 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 0.4 | GO:0005261 | cation channel activity(GO:0005261) |
| 0.0 | 3.0 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.9 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 0.1 | GO:0016670 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670) |
| 0.0 | 0.4 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 0.3 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 0.5 | GO:0008236 | serine-type peptidase activity(GO:0008236) |
| 0.0 | 0.4 | GO:0015464 | acetylcholine receptor activity(GO:0015464) |
| 0.0 | 0.1 | GO:0005471 | ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207) |
| 0.0 | 0.3 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 0.9 | GO:0018024 | histone-lysine N-methyltransferase activity(GO:0018024) |
| 0.0 | 0.2 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.0 | 0.2 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.1 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
| 0.0 | 1.1 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 1.1 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.4 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.1 | GO:0005280 | hydrogen:amino acid symporter activity(GO:0005280) |
| 0.0 | 0.2 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.0 | 0.0 | GO:0004803 | transposase activity(GO:0004803) |
| 0.0 | 0.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.1 | GO:0017040 | ceramidase activity(GO:0017040) |
| 0.0 | 0.2 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 0.5 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 0.4 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 0.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 3.1 | PID IL2 STAT5 PATHWAY | IL2 signaling events mediated by STAT5 |
| 0.0 | 1.0 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.0 | 1.4 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.0 | 1.6 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.8 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 1.4 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.0 | 0.1 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.0 | 2.1 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 2.8 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.8 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.0 | 0.7 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 2.0 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 3.0 | PID P73PATHWAY | p73 transcription factor network |
| 0.0 | 0.2 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.0 | 0.9 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 1.8 | PID TCR PATHWAY | TCR signaling in naïve CD4+ T cells |
| 0.0 | 1.4 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.7 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.2 | PID ERBB4 PATHWAY | ErbB4 signaling events |
| 0.0 | 0.7 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.4 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.6 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 0.1 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.4 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.1 | 1.7 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.1 | 1.9 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.1 | 2.4 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 1.9 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 1.5 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.1 | 1.3 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.1 | 1.1 | REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA | Genes involved in Activation of Chaperones by ATF6-alpha |
| 0.1 | 1.1 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.0 | 0.5 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 1.1 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.0 | 1.3 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 1.8 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 1.9 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.0 | 1.0 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.0 | 3.0 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 1.6 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.7 | REACTOME IL RECEPTOR SHC SIGNALING | Genes involved in Interleukin receptor SHC signaling |
| 0.0 | 1.1 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 0.5 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 0.0 | 2.9 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.0 | 0.4 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.0 | 0.6 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.6 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 1.0 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.6 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 0.2 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.0 | 0.6 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.7 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
| 0.0 | 0.2 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.0 | 0.6 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.2 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 0.4 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 0.5 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.0 | 0.1 | REACTOME INTEGRATION OF ENERGY METABOLISM | Genes involved in Integration of energy metabolism |
| 0.0 | 0.7 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.0 | 0.4 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.0 | 0.4 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 0.2 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.0 | 0.6 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 2.0 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.0 | 0.2 | REACTOME CELL CYCLE CHECKPOINTS | Genes involved in Cell Cycle Checkpoints |
| 0.0 | 1.1 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 1.0 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |