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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GATA1_GATA4

Z-value: 1.29

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Transcription factors associated with GATA1_GATA4

Gene Symbol Gene ID Gene Info
ENSG00000102145.9 GATA binding protein 1
ENSG00000136574.13 GATA binding protein 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GATA4hg19_v2_chr8_+_11534462_11534475-0.844.1e-06Click!
GATA1hg19_v2_chrX_+_48644962_486449830.058.4e-01Click!

Activity profile of GATA1_GATA4 motif

Sorted Z-values of GATA1_GATA4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GATA1_GATA4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.8 3.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.8 5.3 GO:0002786 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.6 6.6 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.5 1.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.4 2.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.4 2.5 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.4 2.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.4 1.5 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.4 2.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.3 1.6 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.3 1.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.3 1.1 GO:0048936 visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913) positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.3 2.0 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 0.7 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 0.7 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.2 1.7 GO:0071461 cellular response to redox state(GO:0071461)
0.2 1.4 GO:0060437 lung growth(GO:0060437)
0.2 1.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.2 0.7 GO:0031247 actin rod assembly(GO:0031247)
0.2 1.3 GO:0051673 membrane disruption in other organism(GO:0051673)
0.2 0.8 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.2 1.0 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 0.7 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2 0.5 GO:0048633 negative regulation of auditory receptor cell differentiation(GO:0045608) positive regulation of skeletal muscle tissue growth(GO:0048633)
0.2 2.2 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.9 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 1.7 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.4 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 1.4 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.6 GO:0071344 diphosphate metabolic process(GO:0071344)
0.1 0.5 GO:0051413 response to cortisone(GO:0051413)
0.1 0.4 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 4.2 GO:0060644 mammary gland epithelial cell differentiation(GO:0060644)
0.1 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.1 0.6 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.5 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 0.2 GO:0007493 endodermal cell fate determination(GO:0007493)
0.1 0.6 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 1.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 1.6 GO:0070970 interleukin-2 secretion(GO:0070970)
0.1 0.8 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 0.7 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.8 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.3 GO:1904000 positive regulation of growth rate(GO:0040010) positive regulation of eating behavior(GO:1904000) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.7 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.4 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 2.1 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.6 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.6 GO:0006196 AMP catabolic process(GO:0006196)
0.1 0.3 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.1 0.8 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 1.0 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.3 GO:2000502 negative regulation of natural killer cell chemotaxis(GO:2000502)
0.1 0.4 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.5 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.4 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 1.2 GO:0001955 blood vessel maturation(GO:0001955)
0.1 1.1 GO:0060613 fat pad development(GO:0060613)
0.1 1.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.4 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.2 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.1 2.4 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.7 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 1.7 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.2 GO:0061485 memory T cell proliferation(GO:0061485)
0.1 0.3 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.7 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.1 0.2 GO:0070781 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.1 2.0 GO:0007398 ectoderm development(GO:0007398)
0.1 0.6 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.4 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.1 2.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.2 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.3 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.6 GO:0030207 chondroitin sulfate catabolic process(GO:0030207)
0.1 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 0.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.2 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.4 GO:1902164 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.8 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 2.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 0.7 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 3.1 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.1 0.7 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.1 0.2 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.1 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.4 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.8 GO:0060056 mammary gland involution(GO:0060056)
0.0 1.1 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.4 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 1.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 1.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.5 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.9 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.3 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 2.7 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.0 0.5 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 1.1 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 2.8 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.4 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 3.0 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.9 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 1.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 1.1 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.1 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 9.2 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.5 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.4 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.6 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 1.2 GO:0015695 organic cation transport(GO:0015695)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 1.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 1.3 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.0 0.5 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.2 GO:0061055 myotome development(GO:0061055)
0.0 1.1 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 3.4 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 0.1 GO:0018874 benzoate metabolic process(GO:0018874)
0.0 0.2 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.4 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.2 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.0 0.2 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.7 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 1.0 GO:0014037 Schwann cell differentiation(GO:0014037)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.4 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 1.0 GO:0043090 amino acid import(GO:0043090)
0.0 1.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.4 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:0015793 glycerol transport(GO:0015793)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.3 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.5 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.7 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.4 GO:0043086 negative regulation of catalytic activity(GO:0043086)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.1 GO:1902262 apoptotic process involved in patterning of blood vessels(GO:1902262)
0.0 0.5 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0 0.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.2 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.2 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.9 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.7 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 1.6 GO:0007049 cell cycle(GO:0007049)
0.0 0.1 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 1.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.7 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.2 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.1 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.0 GO:0036269 swimming behavior(GO:0036269)
0.0 0.2 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.2 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.2 GO:0051607 defense response to virus(GO:0051607)
0.0 0.2 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.1 GO:0072221 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221)
0.0 0.8 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 0.1 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.6 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 1.1 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.0 1.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 1.2 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.5 GO:0016577 histone demethylation(GO:0016577)
0.0 0.3 GO:0007184 SMAD protein import into nucleus(GO:0007184)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 5.3 GO:0097209 epidermal lamellar body(GO:0097209)
0.5 1.9 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.4 3.4 GO:0070876 SOSS complex(GO:0070876)
0.3 2.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 2.2 GO:0005610 laminin-5 complex(GO:0005610)
0.2 6.8 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.1 1.4 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.6 GO:0012505 endomembrane system(GO:0012505)
0.1 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 1.4 GO:0097025 lateral loop(GO:0043219) MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 1.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.9 GO:0061689 tricellular tight junction(GO:0061689)
0.1 1.9 GO:0005922 connexon complex(GO:0005922)
0.1 0.1 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.7 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.7 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.2 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.3 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.1 0.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 3.9 GO:0001533 cornified envelope(GO:0001533)
0.0 1.9 GO:0031105 septin complex(GO:0031105)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 1.8 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 2.7 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 5.1 GO:0005604 basement membrane(GO:0005604)
0.0 0.7 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0051233 spindle midzone(GO:0051233)
0.0 0.4 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.8 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 3.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 0.4 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 2.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.2 GO:0042383 sarcolemma(GO:0042383)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 1.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.5 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.0 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 2.6 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 3.3 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.5 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 1.0 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.8 GO:0015030 Cajal body(GO:0015030)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.0 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 1.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.8 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.2 GO:0031672 A band(GO:0031672)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0002113 interleukin-33 binding(GO:0002113)
0.7 2.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.7 6.4 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5 1.5 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.5 9.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.4 1.7 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.3 0.9 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.3 2.0 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 1.3 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 2.0 GO:0045118 azole transporter activity(GO:0045118)
0.2 3.9 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.2 1.3 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.2 1.5 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 1.9 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 0.8 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 1.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.7 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.4 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 3.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.3 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 1.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.6 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.6 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.3 GO:0031768 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.1 1.9 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.7 GO:0032393 MHC class I receptor activity(GO:0032393)
0.1 0.6 GO:0004882 androgen receptor activity(GO:0004882)
0.1 1.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.8 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.3 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.3 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 3.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 1.3 GO:0042834 peptidoglycan binding(GO:0042834)
0.1 3.4 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 1.6 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.2 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 0.3 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.1 0.7 GO:0046790 virion binding(GO:0046790)
0.1 1.0 GO:0038132 neuregulin binding(GO:0038132)
0.1 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.7 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.6 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 0.5 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 0.4 GO:0050733 RS domain binding(GO:0050733)
0.1 1.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.6 GO:0016015 morphogen activity(GO:0016015)
0.0 0.4 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.4 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.6 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.9 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 5.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 9.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0070016 gamma-catenin binding(GO:0045295) armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.5 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0047756 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.4 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 1.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 1.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 3.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.3 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.0 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.8 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 12.1 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0070008 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.4 GO:0005261 cation channel activity(GO:0005261)
0.0 3.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.9 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 0.4 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.9 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.0 GO:0004803 transposase activity(GO:0004803)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 3.1 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.4 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 3.0 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.9 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 1.8 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.2 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 1.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 2.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.5 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.1 1.1 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 1.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 3.0 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.1 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 2.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.7 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.1 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.7 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.2 REACTOME CELL CYCLE CHECKPOINTS Genes involved in Cell Cycle Checkpoints
0.0 1.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors