ISMARA results: GCUACAU

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GCUACAU

Z-value: 0.58

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miRNA associated with seed GCUACAU

Name	miRBASE accession
hsa-miR-221-3p miRBase	MIMAT0000278
hsa-miR-222-3p miRBase	MIMAT0000279

Activity profile of GCUACAU motif

Sorted Z-values of GCUACAU motif

No targets for GCUACAU

Network of associatons between targets according to the STRING database.

First level regulatory network of GCUACAU

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0002605	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1	1.0	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	0.7	GO:0010609	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0	0.5	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.5	GO:0001573	ganglioside metabolic process(GO:0001573)
0.1	0.4	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.1	0.4	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1	0.4	GO:0021553	olfactory nerve development(GO:0021553)
0.0	0.4	GO:0031087	deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.4	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)

Showing 1 to 10 of 45 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	GO:0005577	fibrinogen complex(GO:0005577)
0.1	1.0	GO:0061700	GATOR2 complex(GO:0061700)
0.2	0.5	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
0.0	0.3	GO:0035976	AP1 complex(GO:0035976)
0.0	0.3	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.3	GO:0031209	SCAR complex(GO:0031209)
0.1	0.2	GO:0097489	multivesicular body, internal vesicle lumen(GO:0097489)
0.0	0.2	GO:1990578	perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0	0.2	GO:0031089	platelet dense granule lumen(GO:0031089)
0.0	0.2	GO:0016600	flotillin complex(GO:0016600)

Showing 1 to 10 of 16 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0070052	collagen V binding(GO:0070052)
0.2	0.5	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.5	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.4	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1	0.3	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.0	0.3	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.3	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0	0.2	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.2	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.2	GO:0072542	protein phosphatase activator activity(GO:0072542)

Showing 1 to 10 of 23 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	0.6	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt

Showing 1 to 4 of 4 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.8	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.3	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors

Showing 1 to 2 of 2 entries

Results for GCUACAU

Z-value: 0.58

Motif logo

miRNA associated with seed GCUACAU

Activity profile of GCUACAU motif

Sorted Z-values of GCUACAU motif

No targets for GCUACAU

Network of associatons between targets according to the STRING database.

First level regulatory network of GCUACAU

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: