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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GGCAGUG

Z-value: 1.38

Motif logo

miRNA associated with seed GGCAGUG

NamemiRBASE accession
MIMAT0000255
MIMAT0000686
MIMAT0001541
MIMAT0003327

Activity profile of GGCAGUG motif

Sorted Z-values of GGCAGUG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GGCAGUG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.8 3.3 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.5 1.6 GO:0051866 general adaptation syndrome(GO:0051866)
0.4 1.6 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.4 1.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.3 0.9 GO:0014016 neuroblast differentiation(GO:0014016)
0.3 6.9 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.2 0.7 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.2 0.7 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 1.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.2 1.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 0.7 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.7 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 2.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 0.3 GO:0002537 nitric oxide production involved in inflammatory response(GO:0002537)
0.1 0.6 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.1 0.7 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.4 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 1.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.1 0.8 GO:0072069 ascending thin limb development(GO:0072021) DCT cell differentiation(GO:0072069) metanephric ascending thin limb development(GO:0072218) metanephric DCT cell differentiation(GO:0072240)
0.1 0.6 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.6 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.5 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.1 1.3 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 1.8 GO:0072718 response to cisplatin(GO:0072718)
0.1 0.5 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 2.7 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.1 0.3 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 1.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.5 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 1.3 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 2.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.6 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.1 0.5 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.7 GO:1903593 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308) regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.3 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.1 0.5 GO:0097350 neutrophil clearance(GO:0097350) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 1.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.6 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.9 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.6 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.5 GO:0051697 protein delipidation(GO:0051697)
0.1 0.9 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1 0.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.6 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 1.2 GO:0021978 telencephalon regionalization(GO:0021978)
0.1 1.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.3 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.3 GO:0031133 regulation of axon diameter(GO:0031133) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.1 0.2 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.1 0.3 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.2 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.1 0.4 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.4 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.5 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.1 0.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.2 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.1 0.3 GO:0072560 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.1 2.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.1 0.8 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.4 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 1.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.2 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.1 1.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.4 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.3 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.3 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 0.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.3 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.4 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.4 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.4 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.4 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0098907 protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.4 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 1.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.4 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 1.0 GO:0021535 cell migration in hindbrain(GO:0021535)
0.0 0.5 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.6 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.6 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.7 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.3 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0015820 leucine transport(GO:0015820)
0.0 0.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.9 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 1.0 GO:0043524 negative regulation of neuron apoptotic process(GO:0043524)
0.0 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.4 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.0 0.1 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.3 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 1.4 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 0.4 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.3 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 2.5 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.7 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.5 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.2 GO:0006390 transcription from mitochondrial promoter(GO:0006390) bone trabecula formation(GO:0060346)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.6 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 1.0 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.2 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.3 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.4 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 1.5 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.4 GO:0046839 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.6 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.7 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.7 3.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 2.0 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 2.1 GO:0005883 neurofilament(GO:0005883)
0.1 1.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 0.5 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.9 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 0.5 GO:0045298 tubulin complex(GO:0045298)
0.1 1.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 0.6 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 2.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.4 GO:0016589 NURF complex(GO:0016589)
0.0 1.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0044305 calyx of Held(GO:0044305)
0.0 0.7 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.5 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.9 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.0 GO:1902710 GABA receptor complex(GO:1902710)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 1.2 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.7 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.5 1.5 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.3 0.9 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 0.8 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.2 0.7 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 0.7 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.2 12.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.2 0.6 GO:0031177 phosphopantetheine binding(GO:0031177)
0.2 0.2 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.4 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 1.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.5 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 1.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.1 0.8 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 4.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.4 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.8 GO:0071837 HMG box domain binding(GO:0071837)
0.1 0.4 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 1.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 1.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.7 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.6 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.3 GO:0005287 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.1 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 0.3 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.1 0.2 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 1.8 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 1.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.6 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.4 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 3.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.8 GO:0016594 glycine binding(GO:0016594)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.6 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 2.9 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0004945 angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.6 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.5 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.4 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.5 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.1 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.4 PID IGF1 PATHWAY IGF1 pathway
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 5.4 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 6.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.0 2.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 2.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 2.1 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.5 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 3.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases