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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GMEB2

Z-value: 3.33

Motif logo

Transcription factors associated with GMEB2

Gene Symbol Gene ID Gene Info
ENSG00000101216.6 glucocorticoid modulatory element binding protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GMEB2hg19_v2_chr20_-_62258394_622584640.184.4e-01Click!

Activity profile of GMEB2 motif

Sorted Z-values of GMEB2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GMEB2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 14.5 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
1.8 5.3 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
1.5 4.5 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.9 2.8 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.9 3.5 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.8 2.5 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.8 3.0 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.7 4.0 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.6 2.5 GO:0051664 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.6 5.7 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.6 2.5 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.6 3.7 GO:0048388 endosomal lumen acidification(GO:0048388)
0.6 11.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.6 2.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.6 1.8 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.6 1.7 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.5 2.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.5 2.7 GO:1901536 negative regulation of DNA demethylation(GO:1901536)
0.5 1.6 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.5 6.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.5 3.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.5 2.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.5 2.0 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.5 4.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.5 4.7 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.4 1.7 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.4 2.1 GO:0035617 stress granule disassembly(GO:0035617)
0.4 1.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.4 2.8 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.4 3.5 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.4 2.7 GO:0006041 glucosamine metabolic process(GO:0006041)
0.4 1.5 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.4 3.0 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.4 2.3 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.4 2.8 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.4 2.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.4 1.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.3 1.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.3 1.7 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.3 1.0 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.3 1.0 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.3 1.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.3 3.0 GO:0030242 pexophagy(GO:0030242)
0.3 1.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.3 1.0 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.3 1.0 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.3 1.6 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.3 4.7 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.3 0.9 GO:0033341 regulation of collagen binding(GO:0033341)
0.3 1.8 GO:0072752 cellular response to rapamycin(GO:0072752)
0.3 1.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.3 2.8 GO:0075713 establishment of integrated proviral latency(GO:0075713)
0.3 0.8 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.3 1.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.3 5.0 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.3 4.0 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.3 0.8 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.3 1.6 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 0.8 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.3 0.8 GO:0007113 endomitotic cell cycle(GO:0007113)
0.3 1.3 GO:1904751 positive regulation of telomeric DNA binding(GO:1904744) positive regulation of protein localization to nucleolus(GO:1904751)
0.3 0.8 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.3 1.8 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.2 2.0 GO:0042256 mature ribosome assembly(GO:0042256) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.2 1.5 GO:0030047 actin modification(GO:0030047)
0.2 4.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.2 2.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.2 0.2 GO:0035698 CD8-positive, alpha-beta T cell extravasation(GO:0035697) CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:0035698) regulation of T cell extravasation(GO:2000407) regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449) regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation(GO:2000452)
0.2 5.4 GO:0050942 positive regulation of pigment cell differentiation(GO:0050942)
0.2 1.9 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 0.7 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.2 1.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.2 0.9 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.2 0.7 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 1.8 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.2 2.7 GO:0007000 nucleolus organization(GO:0007000)
0.2 1.1 GO:0006203 dGTP catabolic process(GO:0006203)
0.2 1.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.2 1.3 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 2.2 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.2 0.9 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.2 1.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 1.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.2 3.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.2 1.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.2 2.3 GO:0000012 single strand break repair(GO:0000012)
0.2 1.0 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.2 3.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 1.4 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 2.0 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.2 0.8 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.2 1.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.2 1.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 5.1 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.2 2.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.2 3.1 GO:0015693 magnesium ion transport(GO:0015693)
0.2 1.3 GO:1902896 terminal web assembly(GO:1902896)
0.2 1.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 0.6 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.2 0.7 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.2 2.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 1.1 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.2 0.9 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.2 0.5 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.2 2.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.7 GO:0042126 nitrate metabolic process(GO:0042126)
0.2 1.4 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.2 0.5 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.2 2.0 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.2 0.5 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.2 0.7 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.2 0.5 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 0.8 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.2 0.6 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2 1.6 GO:0034036 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 2.5 GO:0044351 macropinocytosis(GO:0044351)
0.2 2.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.2 3.6 GO:0007379 segment specification(GO:0007379)
0.2 1.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.2 0.9 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 1.2 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.3 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 0.7 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.1 7.4 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 0.6 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.1 1.0 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 4.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 3.8 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.1 0.4 GO:2000437 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.1 0.7 GO:2000255 regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255)
0.1 1.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 1.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 1.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1 2.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 3.9 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.6 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 1.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.4 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 5.8 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.1 0.3 GO:0051257 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 2.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.0 GO:0006021 inositol biosynthetic process(GO:0006021)
0.1 0.8 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.8 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.4 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1 1.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 0.9 GO:0070970 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) interleukin-2 secretion(GO:0070970)
0.1 1.7 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 0.9 GO:2001138 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.1 1.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.5 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.1 0.5 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) endothelial tip cell fate specification(GO:0097102) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 2.1 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.1 0.1 GO:0046102 adenosine catabolic process(GO:0006154) hypoxanthine salvage(GO:0043103) inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.1 1.1 GO:0006983 ER overload response(GO:0006983)
0.1 1.7 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 2.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.1 0.9 GO:0090656 t-circle formation(GO:0090656)
0.1 0.6 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.9 GO:0035898 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.1 0.8 GO:0070265 necrotic cell death(GO:0070265)
0.1 0.3 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.1 0.9 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 1.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 1.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.1 1.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.4 GO:0070417 cellular response to cold(GO:0070417)
0.1 1.0 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 1.3 GO:0048368 lateral mesoderm development(GO:0048368)
0.1 0.8 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.1 0.3 GO:0090410 malonate catabolic process(GO:0090410)
0.1 1.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.3 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 2.4 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
0.1 3.4 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.3 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.1 0.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 1.4 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 1.2 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744)
0.1 0.3 GO:0000082 G1/S transition of mitotic cell cycle(GO:0000082)
0.1 1.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.1 0.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 2.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 1.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 1.7 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.8 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.1 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.1 2.8 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.1 1.6 GO:0034453 microtubule anchoring(GO:0034453)
0.1 0.9 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 4.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.5 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 1.4 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.6 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.1 0.6 GO:0071901 negative regulation of protein serine/threonine kinase activity(GO:0071901)
0.1 0.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 2.5 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.4 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
0.1 0.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.8 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.1 1.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.8 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 1.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 0.2 GO:0008628 hormone-mediated apoptotic signaling pathway(GO:0008628)
0.1 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 1.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.1 0.1 GO:1904978 regulation of endosome organization(GO:1904978)
0.1 0.2 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 0.9 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.7 GO:0036010 protein localization to endosome(GO:0036010)
0.1 0.2 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.7 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.1 0.4 GO:0060017 parathyroid gland development(GO:0060017)
0.1 0.2 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.1 3.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 0.4 GO:0060846 blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) blood vessel endothelial cell fate specification(GO:0097101)
0.0 1.7 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 1.0 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 2.1 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 1.5 GO:0032060 bleb assembly(GO:0032060)
0.0 1.5 GO:0006400 tRNA modification(GO:0006400)
0.0 2.9 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.2 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.5 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 3.7 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
0.0 1.1 GO:0007097 nuclear migration(GO:0007097)
0.0 1.8 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 1.6 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 3.6 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 2.4 GO:0007616 long-term memory(GO:0007616)
0.0 1.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124) regulation of GTP binding(GO:1904424)
0.0 3.8 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.5 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.4 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.5 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0 1.5 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.7 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 1.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 1.7 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.4 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.7 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.3 GO:0031438 negative regulation of mRNA cleavage(GO:0031438) negative regulation of IRE1-mediated unfolded protein response(GO:1903895) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 3.0 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 1.1 GO:0007099 centriole replication(GO:0007099)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 1.5 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0006924 activation-induced cell death of T cells(GO:0006924)
0.0 0.4 GO:0070141 response to UV-A(GO:0070141)
0.0 0.9 GO:0036119 response to platelet-derived growth factor(GO:0036119) cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.9 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.0 0.9 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.4 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 4.1 GO:0046324 regulation of glucose import(GO:0046324)
0.0 5.3 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 3.8 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 1.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.5 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.0 2.0 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.8 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.4 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.4 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 1.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.7 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.4 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.2 GO:0042262 DNA protection(GO:0042262)
0.0 0.5 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.0 0.1 GO:0014823 response to activity(GO:0014823)
0.0 0.5 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.4 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 0.6 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.5 GO:0003094 glomerular filtration(GO:0003094)
0.0 1.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 2.7 GO:0000910 cytokinesis(GO:0000910)
0.0 2.7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.9 GO:0006110 regulation of glycolytic process(GO:0006110)
0.0 0.7 GO:0034030 coenzyme A biosynthetic process(GO:0015937) nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 1.2 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.6 GO:0050776 regulation of immune response(GO:0050776)
0.0 0.9 GO:0014003 oligodendrocyte development(GO:0014003)
0.0 1.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0051775 response to redox state(GO:0051775)
0.0 0.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.3 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.9 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.2 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.2 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
0.0 0.3 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.2 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:2001171 regulation of ATP biosynthetic process(GO:2001169) positive regulation of ATP biosynthetic process(GO:2001171)
0.0 1.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.2 GO:0018022 peptidyl-lysine methylation(GO:0018022)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 2.6 GO:0007286 spermatid development(GO:0007286)
0.0 0.6 GO:0006979 response to oxidative stress(GO:0006979)
0.0 1.5 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.1 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.0 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.5 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.9 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.8 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:1902099 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0 1.1 GO:2000177 regulation of neural precursor cell proliferation(GO:2000177)
0.0 0.5 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.9 GO:0035065 regulation of histone acetylation(GO:0035065)
0.0 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0061055 myotome development(GO:0061055)
0.0 0.5 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.2 GO:0010165 response to X-ray(GO:0010165)
0.0 0.0 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:1990423 RZZ complex(GO:1990423)
0.8 11.7 GO:0042587 glycogen granule(GO:0042587)
0.7 2.2 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.7 4.0 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.6 3.8 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.5 4.3 GO:0097452 GAIT complex(GO:0097452)
0.5 3.0 GO:0097149 centralspindlin complex(GO:0097149)
0.5 6.4 GO:0000796 condensin complex(GO:0000796)
0.5 4.7 GO:0000125 PCAF complex(GO:0000125)
0.5 1.4 GO:0097134 Y chromosome(GO:0000806) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134)
0.5 1.8 GO:0071001 U4/U6 snRNP(GO:0071001)
0.4 2.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.4 1.3 GO:0097637 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.4 7.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.4 1.5 GO:0005846 nuclear cap binding complex(GO:0005846)
0.4 1.4 GO:0055087 Ski complex(GO:0055087)
0.3 1.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 1.0 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.3 2.2 GO:0090661 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.3 2.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.3 4.2 GO:0000124 SAGA complex(GO:0000124)
0.3 1.5 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.3 0.9 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.3 1.4 GO:0034457 Mpp10 complex(GO:0034457)
0.3 1.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.3 1.3 GO:0031417 NatC complex(GO:0031417)
0.3 1.3 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 1.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 8.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 5.8 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.2 0.9 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.2 0.6 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.2 2.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 2.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 1.0 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 3.4 GO:0097227 sperm annulus(GO:0097227)
0.2 3.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.2 1.3 GO:1990357 terminal web(GO:1990357)
0.2 1.1 GO:0098536 deuterosome(GO:0098536)
0.2 3.6 GO:0035102 PRC1 complex(GO:0035102)
0.2 1.8 GO:0031298 replication fork protection complex(GO:0031298)
0.2 4.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 2.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.4 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.7 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.1 1.6 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.1 GO:0032437 cuticular plate(GO:0032437)
0.1 3.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 2.6 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.9 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.9 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.5 GO:0042585 germinal vesicle(GO:0042585)
0.1 1.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 2.1 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.3 GO:0005715 late recombination nodule(GO:0005715)
0.1 1.8 GO:0031931 TORC1 complex(GO:0031931)
0.1 0.7 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.4 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.1 2.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 1.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.6 GO:0019012 virion(GO:0019012) virion part(GO:0044423)
0.1 1.1 GO:0042382 paraspeckles(GO:0042382)
0.1 1.6 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 2.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 2.0 GO:0032433 filopodium tip(GO:0032433)
0.1 1.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 1.6 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.8 GO:0098845 postsynaptic endosome(GO:0098845)
0.1 0.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 1.8 GO:0032156 septin cytoskeleton(GO:0032156)
0.1 0.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.4 GO:0005869 dynactin complex(GO:0005869)
0.1 10.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 1.2 GO:0045180 basal cortex(GO:0045180)
0.1 0.8 GO:0000322 storage vacuole(GO:0000322)
0.1 1.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 2.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 1.3 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 1.0 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.7 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 2.7 GO:0002080 acrosomal membrane(GO:0002080)
0.1 1.1 GO:0001741 XY body(GO:0001741)
0.1 1.0 GO:0034464 BBSome(GO:0034464)
0.1 1.1 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.3 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.2 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.5 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.1 1.3 GO:0070938 contractile ring(GO:0070938)
0.1 1.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 6.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.8 GO:0072487 MSL complex(GO:0072487)
0.1 3.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 0.9 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 2.2 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.1 0.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.0 GO:0042555 MCM complex(GO:0042555)
0.1 1.3 GO:0016580 Sin3 complex(GO:0016580)
0.1 2.3 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.6 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 5.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0097443 sorting endosome(GO:0097443)
0.0 7.6 GO:0016605 PML body(GO:0016605)
0.0 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 2.0 GO:0005921 gap junction(GO:0005921)
0.0 2.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 4.8 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 1.2 GO:0051233 spindle midzone(GO:0051233)
0.0 1.0 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 2.7 GO:0030684 preribosome(GO:0030684)
0.0 0.8 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0097342 ripoptosome(GO:0097342)
0.0 1.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.5 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.8 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 3.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 1.2 GO:0015030 Cajal body(GO:0015030)
0.0 0.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 1.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.3 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 0.4 GO:0043203 axon hillock(GO:0043203)
0.0 0.8 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 1.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.1 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 3.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.5 GO:0043204 perikaryon(GO:0043204)
0.0 3.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 4.1 GO:0030496 midbody(GO:0030496)
0.0 9.3 GO:0005769 early endosome(GO:0005769)
0.0 0.4 GO:0031045 dense core granule(GO:0031045)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0044306 neuron projection terminus(GO:0044306)
0.0 1.6 GO:0043195 terminal bouton(GO:0043195)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 8.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0044439 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.6 GO:0000922 spindle pole(GO:0000922)
0.0 0.3 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)
0.0 4.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 2.2 GO:0045111 intermediate filament cytoskeleton(GO:0045111)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 11.7 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
1.8 5.3 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.8 0.8 GO:0017076 purine nucleotide binding(GO:0017076)
0.7 3.7 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.7 2.1 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.7 2.8 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.6 2.5 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.6 3.7 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.6 2.4 GO:0098808 mRNA cap binding(GO:0098808)
0.6 1.8 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.5 2.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.5 1.9 GO:0031685 adenosine receptor binding(GO:0031685)
0.4 3.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.4 3.6 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.4 1.7 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.4 1.7 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.4 2.1 GO:0031403 lithium ion binding(GO:0031403)
0.4 5.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.4 2.3 GO:0039552 RIG-I binding(GO:0039552)
0.4 2.2 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.4 1.1 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.4 1.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.4 4.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.4 1.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.3 1.0 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.3 1.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 1.0 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
0.3 3.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.3 0.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.3 15.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 0.9 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.3 1.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.3 5.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 1.5 GO:0097677 STAT family protein binding(GO:0097677)
0.3 1.2 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.3 2.4 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.3 1.5 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.3 1.5 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.3 0.9 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.3 0.8 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908)
0.3 0.8 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.3 1.6 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.3 0.8 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 2.7 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 5.8 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.2 0.9 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 4.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.2 6.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.2 2.4 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.2 2.8 GO:0033592 RNA strand annealing activity(GO:0033592)
0.2 1.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.2 1.3 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.2 1.4 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 1.8 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 1.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 2.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 1.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.2 3.0 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.2 0.6 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.6 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.2 1.7 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 0.6 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.2 2.0 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.2 2.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 6.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 4.1 GO:0043422 protein kinase B binding(GO:0043422)
0.2 0.9 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.7 GO:0043515 kinetochore binding(GO:0043515)
0.2 1.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.2 1.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 1.8 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.2 0.8 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.2 1.0 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.2 4.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.2 0.8 GO:0017089 glycolipid transporter activity(GO:0017089)
0.2 2.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.2 1.2 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.1 1.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 1.3 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.1 5.8 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.9 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.7 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.7 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 1.8 GO:0031386 protein tag(GO:0031386)
0.1 4.3 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 1.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 4.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 0.9 GO:0000405 bubble DNA binding(GO:0000405)
0.1 3.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.4 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 4.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 1.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.6 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.1 0.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.6 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 3.7 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 0.5 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.1 3.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 5.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 4.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.6 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 1.6 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.6 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 2.0 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1 1.0 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 5.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.8 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.9 GO:0045545 syndecan binding(GO:0045545)
0.1 0.9 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.1 2.1 GO:0035173 histone kinase activity(GO:0035173)
0.1 1.0 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 4.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.3 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.1 1.0 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 3.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.2 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 2.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 7.7 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 3.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 1.0 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.2 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.1 0.3 GO:0032427 GBD domain binding(GO:0032427)
0.1 0.9 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 1.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 0.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 1.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.5 GO:0038191 neuropilin binding(GO:0038191)
0.1 5.8 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 1.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.1 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.1 0.3 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 1.8 GO:0004707 MAP kinase activity(GO:0004707)
0.1 2.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.8 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 2.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.2 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.4 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 0.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.2 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.8 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 2.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.6 GO:0042171 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 3.4 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.5 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 2.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.8 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.2 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 2.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.9 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 1.2 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 2.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 2.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.4 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.3 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 2.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.2 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 1.1 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.5 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 1.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.0 GO:0005123 death receptor binding(GO:0005123)
0.0 0.4 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0038025 reelin receptor activity(GO:0038025)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 1.1 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 2.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.9 GO:0019003 GDP binding(GO:0019003)
0.0 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 1.5 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.4 GO:0048185 activin binding(GO:0048185)
0.0 1.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0016301 kinase activity(GO:0016301)
0.0 5.7 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 2.3 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.1 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 6.0 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.4 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.7 GO:0019208 phosphatase regulator activity(GO:0019208)
0.0 0.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 8.0 GO:0045296 cadherin binding(GO:0045296)
0.0 2.2 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0009374 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.5 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 2.2 GO:0044325 ion channel binding(GO:0044325)
0.0 1.0 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.3 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.8 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.3 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.1 GO:0070403 NAD+ binding(GO:0070403)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 15.4 PID PLK1 PATHWAY PLK1 signaling events
0.1 2.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 8.0 PID AURORA B PATHWAY Aurora B signaling
0.1 2.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 7.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 4.7 PID MYC PATHWAY C-MYC pathway
0.1 4.6 PID ATM PATHWAY ATM pathway
0.1 1.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 3.4 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 2.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.1 3.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 5.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 5.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 3.7 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 0.9 PID IL5 PATHWAY IL5-mediated signaling events
0.1 3.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 2.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 2.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 1.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 3.5 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 3.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 4.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 2.8 PID BCR 5PATHWAY BCR signaling pathway
0.0 2.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 2.4 PID E2F PATHWAY E2F transcription factor network
0.0 1.0 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 2.3 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 1.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.8 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.4 14.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 11.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 3.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 8.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 4.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.2 3.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 0.5 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2 6.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 3.8 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 7.2 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.1 9.7 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 4.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 5.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 1.9 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 3.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.8 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 2.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 3.0 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
0.1 2.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 2.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 3.9 REACTOME KINESINS Genes involved in Kinesins
0.1 2.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.0 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 1.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.8 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 1.7 REACTOME METABOLISM OF RNA Genes involved in Metabolism of RNA
0.1 0.8 REACTOME TRANSCRIPTION COUPLED NER TC NER Genes involved in Transcription-coupled NER (TC-NER)
0.1 4.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 2.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 4.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 8.0 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.1 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 0.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 1.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.9 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 3.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.9 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.2 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.9 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.7 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 3.7 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 2.1 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 2.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 0.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 3.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.0 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 4.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 4.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 6.4 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.1 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation