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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GTF2I

Z-value: 1.33

Motif logo

Transcription factors associated with GTF2I

Gene Symbol Gene ID Gene Info
ENSG00000077809.8 general transcription factor IIi

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GTF2Ihg19_v2_chr7_+_74072288_740723570.587.0e-03Click!

Activity profile of GTF2I motif

Sorted Z-values of GTF2I motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GTF2I

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0021623 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.4 1.8 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.4 1.4 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.3 3.4 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.3 1.0 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.3 1.7 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.3 1.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 1.9 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.3 0.8 GO:0045041 B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041)
0.3 0.8 GO:0001300 chronological cell aging(GO:0001300)
0.3 0.8 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.3 1.0 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.2 1.5 GO:0070384 Harderian gland development(GO:0070384)
0.2 1.7 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.2 1.0 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 0.7 GO:1901420 negative regulation of vitamin D receptor signaling pathway(GO:0070563) negative regulation of response to alcohol(GO:1901420)
0.2 1.4 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.2 0.6 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.2 2.6 GO:0006477 protein sulfation(GO:0006477)
0.2 0.7 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.2 0.7 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 0.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 2.5 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 0.7 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 1.3 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.7 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.1 0.8 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.4 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.1 0.4 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 2.0 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 1.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.4 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.7 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 1.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 5.1 GO:0006783 heme biosynthetic process(GO:0006783)
0.1 0.3 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.1 0.7 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.3 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 0.4 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.3 GO:0050822 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1 0.3 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.3 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.1 0.4 GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.1 0.5 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.1 1.5 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.5 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.3 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.5 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.5 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.3 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 1.1 GO:0060982 coronary artery morphogenesis(GO:0060982)
0.1 1.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.3 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.1 0.8 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.2 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 1.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:1900155 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.1 0.2 GO:0052255 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1 0.2 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.4 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.1 0.2 GO:0071109 superior temporal gyrus development(GO:0071109)
0.1 0.5 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.1 0.3 GO:0051796 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.3 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 0.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.4 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 0.2 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.8 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 0.2 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.4 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.1 0.2 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.1 0.4 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 0.3 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.2 GO:0048627 myoblast development(GO:0048627)
0.1 0.2 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.3 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
0.1 0.8 GO:0060056 mammary gland involution(GO:0060056)
0.1 0.6 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.5 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1 0.5 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 0.3 GO:1990927 vesicle-mediated cholesterol transport(GO:0090119) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 1.5 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.7 GO:1904379 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.1 0.3 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.1 0.6 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1 0.7 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.3 GO:0061015 snRNA import into nucleus(GO:0061015)
0.1 0.2 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.1 1.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.9 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 1.6 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.4 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
0.1 0.6 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.1 0.2 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.2 GO:1905044 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.1 0.5 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.1 0.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.1 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 1.0 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 1.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.6 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.1 1.1 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.3 GO:0071543 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.3 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.9 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.1 0.3 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1 0.3 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.1 0.3 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.7 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 1.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.2 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 0.2 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.2 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.4 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0086044 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.0 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.3 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.5 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.4 GO:0019255 glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.8 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0 0.5 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.1 GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.5 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 3.4 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.3 GO:0014004 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.0 0.1 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.0 0.1 GO:0046349 UDP-N-acetylglucosamine biosynthetic process(GO:0006048) amino sugar biosynthetic process(GO:0046349)
0.0 0.2 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.3 GO:0097048 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.6 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0002192 IRES-dependent translational initiation(GO:0002192)
0.0 0.1 GO:0048075 positive regulation of eye pigmentation(GO:0048075)
0.0 0.2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.3 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.2 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.5 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.5 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 1.2 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.3 GO:0019075 virus maturation(GO:0019075)
0.0 0.1 GO:0090472 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.0 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.2 GO:0071897 DNA biosynthetic process(GO:0071897)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.7 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 1.1 GO:0016246 RNA interference(GO:0016246)
0.0 0.8 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 1.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:1903450 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.2 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) positive regulation of prolactin secretion(GO:1902722) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.2 GO:0097327 response to antineoplastic agent(GO:0097327) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.5 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.3 GO:1990834 response to odorant(GO:1990834)
0.0 0.5 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.3 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0016321 female meiosis chromosome segregation(GO:0016321)
0.0 0.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.5 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.5 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:1902811 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:1904117 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.7 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.2 GO:0006868 glutamine transport(GO:0006868) L-cystine transport(GO:0015811)
0.0 0.7 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.3 GO:0060413 atrial septum morphogenesis(GO:0060413)
0.0 0.4 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.6 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 1.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.6 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.2 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.8 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.0 0.4 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.8 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.1 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.0 0.6 GO:0014741 negative regulation of cardiac muscle hypertrophy(GO:0010614) negative regulation of muscle hypertrophy(GO:0014741)
0.0 0.1 GO:1902617 response to fluoride(GO:1902617)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.2 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.2 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.6 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.0 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.2 GO:0010452 regulation of histone H3-K36 methylation(GO:0000414) histone H3-K36 methylation(GO:0010452)
0.0 0.7 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.3 GO:0015684 ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0 0.0 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.3 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:0043622 cortical microtubule organization(GO:0043622) establishment of centrosome localization(GO:0051660)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0001768 establishment of T cell polarity(GO:0001768)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.0 GO:0010159 specification of organ position(GO:0010159)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.0 0.6 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.3 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.2 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:1901725 regulation of histone deacetylase activity(GO:1901725)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.2 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.3 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.5 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.0 0.3 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.0 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.5 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 1.1 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.0 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.0 GO:1903060 regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.0 1.1 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.0 0.6 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.8 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 1.7 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.2 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.4 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.8 GO:0045453 bone resorption(GO:0045453)
0.0 0.4 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.3 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.3 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.2 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.0 0.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.1 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.4 GO:0036065 fucosylation(GO:0036065)
0.0 0.1 GO:0097012 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0051798 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 1.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.0 GO:0001777 T cell homeostatic proliferation(GO:0001777)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 2.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0006412 translation(GO:0006412)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.2 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway(GO:2001237)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.3 2.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.7 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)
0.2 0.7 GO:0097444 spine apparatus(GO:0097444)
0.2 0.7 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 1.5 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 1.4 GO:0097209 epidermal lamellar body(GO:0097209)
0.2 0.2 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.2 0.9 GO:0071942 XPC complex(GO:0071942)
0.2 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 2.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.5 GO:1990032 parallel fiber(GO:1990032)
0.1 0.6 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 0.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.3 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.5 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1 0.3 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 0.3 GO:0036117 hyaluranon cable(GO:0036117)
0.1 0.8 GO:0097452 GAIT complex(GO:0097452)
0.1 2.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.4 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.9 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 2.3 GO:0071564 npBAF complex(GO:0071564)
0.1 0.7 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.4 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.5 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.1 GO:0097422 tubular endosome(GO:0097422)
0.1 0.5 GO:0032437 cuticular plate(GO:0032437)
0.1 0.2 GO:0045160 myosin I complex(GO:0045160)
0.1 0.7 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.7 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.2 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0075341 host cell PML body(GO:0075341)
0.0 0.3 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.8 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.8 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.3 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.2 GO:0072534 perineuronal net(GO:0072534)
0.0 0.4 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.2 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0031417 NatC complex(GO:0031417)
0.0 1.1 GO:0031143 pseudopodium(GO:0031143)
0.0 1.5 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 1.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.8 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.1 GO:0005595 collagen type XII trimer(GO:0005595)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.7 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 1.0 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.6 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 2.4 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0030904 retromer complex(GO:0030904)
0.0 3.2 GO:0042641 actomyosin(GO:0042641)
0.0 0.4 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 2.7 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.7 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 1.1 GO:0001772 immunological synapse(GO:0001772)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0032797 SMN complex(GO:0032797) SMN-Sm protein complex(GO:0034719)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.0 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.0 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 1.9 GO:0005884 actin filament(GO:0005884)
0.0 0.1 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.1 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.0 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.0 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.4 GO:1990752 microtubule end(GO:1990752)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.1 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 1.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0033643 host cell part(GO:0033643)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.4 2.6 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.3 1.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.9 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.2 0.5 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.2 0.5 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 1.0 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.2 0.5 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.4 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.8 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 1.3 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.1 0.3 GO:0036440 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 2.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 4.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.3 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.1 0.3 GO:0005199 structural constituent of cell wall(GO:0005199)
0.1 0.3 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 0.5 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.3 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.6 GO:0042835 BRE binding(GO:0042835)
0.1 1.4 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 3.7 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 1.8 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 0.1 GO:0048185 activin binding(GO:0048185)
0.1 1.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.1 GO:0038064 collagen receptor activity(GO:0038064)
0.1 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 1.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.5 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.3 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.1 0.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433)
0.1 2.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.4 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.3 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.1 0.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 0.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.3 GO:0052844 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 1.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 1.8 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.2 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 0.3 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.1 0.3 GO:0039552 RIG-I binding(GO:0039552)
0.1 0.9 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.1 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.3 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.1 0.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.3 GO:0097001 ceramide binding(GO:0097001)
0.0 0.4 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0086076 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.0 0.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.9 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 1.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 3.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0086039 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.0 0.5 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.4 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 1.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.6 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.0 0.2 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.3 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.7 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.7 GO:0048156 tau protein binding(GO:0048156)
0.0 0.6 GO:0008517 folic acid transporter activity(GO:0008517)
0.0 0.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 1.6 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 1.6 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0003867 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.2 GO:0045118 azole transporter activity(GO:0045118)
0.0 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.2 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.7 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.3 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 1.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 2.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.9 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0005115 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.9 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 2.6 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 1.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.4 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.8 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0003678 DNA helicase activity(GO:0003678)
0.0 1.6 GO:0070035 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.2 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.0 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.2 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.1 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.0 GO:0031433 telethonin binding(GO:0031433)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0098639 protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 2.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 4.3 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 ST STAT3 PATHWAY STAT3 Pathway
0.0 3.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 3.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.0 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 2.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 2.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID IGF1 PATHWAY IGF1 pathway
0.0 2.4 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.8 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 2.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.2 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.1 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.2 0.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.2 2.5 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 2.0 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 2.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.2 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 2.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 4.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 2.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.6 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.9 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.5 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.5 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.6 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 3.3 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling