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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GUAACAG

Z-value: 0.60

Motif logo

miRNA associated with seed GUAACAG

NamemiRBASE accession
MIMAT0000460

Activity profile of GUAACAG motif

Sorted Z-values of GUAACAG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAACAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.9 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.6 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.6 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.5 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.3 GO:0048007 synaptic vesicle recycling via endosome(GO:0036466) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.4 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.6 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.3 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.1 0.3 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.2 GO:0045210 FasL biosynthetic process(GO:0045210)
0.1 1.0 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.1 GO:0071109 superior temporal gyrus development(GO:0071109)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.3 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.2 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.0 0.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.2 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.3 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0070052 collagen V binding(GO:0070052)
0.1 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.0 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.9 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.6 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.5 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.9 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)