ISMARA results: GUGCAAA

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GUGCAAA

Z-value: 1.50

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miRNA associated with seed GUGCAAA

Name	miRBASE accession
hsa-miR-19a-3p miRBase	MIMAT0000073
hsa-miR-19b-3p miRBase	MIMAT0000074

Activity profile of GUGCAAA motif

Sorted Z-values of GUGCAAA motif

No targets for GUGCAAA

Network of associatons between targets according to the STRING database.

First level regulatory network of GUGCAAA

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.7	GO:0042744	hydrogen peroxide catabolic process(GO:0042744)
0.0	3.7	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
1.2	3.5	GO:0002605	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1	3.3	GO:0071481	cellular response to X-ray(GO:0071481)
0.2	3.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	3.0	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.5	2.8	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.3	2.8	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1	2.5	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	2.3	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)

Showing 1 to 10 of 221 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.1	GO:0055037	recycling endosome(GO:0055037)
0.0	3.9	GO:0005811	lipid particle(GO:0005811)
0.2	3.5	GO:0005577	fibrinogen complex(GO:0005577)
0.4	3.3	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	3.2	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	3.2	GO:0016605	PML body(GO:0016605)
0.0	2.9	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	2.9	GO:0016528	sarcoplasm(GO:0016528)
0.0	2.7	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	2.5	GO:0090543	Flemming body(GO:0090543)

Showing 1 to 10 of 91 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.7	3.7	GO:0005152	interleukin-1 receptor antagonist activity(GO:0005152)
0.9	3.5	GO:0070052	collagen V binding(GO:0070052)
0.1	2.8	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.1	2.5	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1	2.5	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	2.0	GO:0004707	MAP kinase activity(GO:0004707)
0.0	2.0	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	2.0	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	2.0	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.5	1.9	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)

Showing 1 to 10 of 139 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	4.8	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	3.5	PID LKB1 PATHWAY	LKB1 signaling events
0.1	3.4	PID ALK1 PATHWAY	ALK1 signaling events
0.1	3.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	3.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	3.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	2.8	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	2.6	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	1.9	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	1.7	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction

Showing 1 to 10 of 30 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	4.1	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	3.7	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	3.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	2.6	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0	2.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	2.5	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1	2.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	2.0	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	1.9	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.7	REACTOME PROLONGED ERK ACTIVATION EVENTS	Genes involved in Prolonged ERK activation events

Showing 1 to 10 of 48 entries

Results for GUGCAAA

Z-value: 1.50

Motif logo

miRNA associated with seed GUGCAAA

Activity profile of GUGCAAA motif

Sorted Z-values of GUGCAAA motif

No targets for GUGCAAA

Network of associatons between targets according to the STRING database.

First level regulatory network of GUGCAAA

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: