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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HES1

Z-value: 2.42

Motif logo

Transcription factors associated with HES1

Gene Symbol Gene ID Gene Info
ENSG00000114315.3 hes family bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HES1hg19_v2_chr3_+_193853927_193853944-0.623.5e-03Click!

Activity profile of HES1 motif

Sorted Z-values of HES1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HES1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0043181 vacuolar sequestering(GO:0043181)
1.4 4.2 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
1.4 4.2 GO:0035623 renal glucose absorption(GO:0035623)
1.3 3.9 GO:0003168 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
1.2 6.0 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
1.0 4.0 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
1.0 4.9 GO:0036343 psychomotor behavior(GO:0036343)
0.8 3.2 GO:0060032 notochord regression(GO:0060032)
0.8 2.4 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.8 2.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.6 2.5 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.6 3.8 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.6 2.5 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.6 4.8 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.6 1.8 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.6 2.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.5 1.6 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.5 1.6 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.5 2.2 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.5 2.7 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.5 1.5 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.5 1.5 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.5 2.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.4 1.3 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.4 2.6 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.4 1.3 GO:1900369 transcription, RNA-templated(GO:0001172) negative regulation of RNA interference(GO:1900369)
0.4 2.5 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.4 1.2 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.4 5.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.4 1.2 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.4 5.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.4 1.6 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.4 1.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.4 1.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.4 1.9 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.4 1.1 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.4 3.6 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.4 1.1 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.3 2.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 3.1 GO:1904386 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.3 1.3 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.3 2.9 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.3 2.5 GO:0007498 mesoderm development(GO:0007498)
0.3 0.9 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.3 1.2 GO:0008355 olfactory learning(GO:0008355)
0.3 0.3 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.3 1.2 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.3 2.0 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.3 0.6 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.3 1.4 GO:0031296 B cell costimulation(GO:0031296)
0.3 2.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.3 1.2 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.3 1.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.3 2.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.3 0.8 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.3 1.9 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.3 1.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 1.0 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.2 1.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 0.7 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.2 2.7 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.2 1.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.2 1.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 1.9 GO:0055064 chloride ion homeostasis(GO:0055064)
0.2 1.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 2.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 1.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 0.8 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.2 2.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.2 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.2 0.8 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.2 0.8 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.2 4.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 1.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.2 0.6 GO:0006097 glyoxylate cycle(GO:0006097)
0.2 0.8 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.2 0.8 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.2 0.6 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.2 0.9 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.2 0.9 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 0.7 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.2 3.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.2 1.3 GO:0021546 rhombomere development(GO:0021546) midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.2 0.3 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.2 1.0 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.2 0.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.2 0.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.5 GO:0061010 endodermal cell fate determination(GO:0007493) regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796) gall bladder development(GO:0061010)
0.2 0.5 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.2 2.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 0.6 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 0.8 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 1.9 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 3.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.7 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.1 0.7 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 1.0 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.1 0.4 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 1.3 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.1 1.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 1.0 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.1 0.6 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 2.6 GO:0019532 oxalate transport(GO:0019532)
0.1 1.2 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.1 0.5 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 2.9 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.1 1.2 GO:0099515 nuclear migration along microfilament(GO:0031022) actin filament-based transport(GO:0099515)
0.1 0.4 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 1.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 1.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 1.4 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.5 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.4 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 1.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 1.3 GO:0015820 leucine transport(GO:0015820)
0.1 0.5 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 7.3 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 2.3 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 1.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 1.2 GO:0097338 response to clozapine(GO:0097338)
0.1 0.5 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.7 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.4 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.1 0.7 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 1.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.2 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.1 1.6 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 1.9 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.1 0.4 GO:0003274 endocardial cushion fusion(GO:0003274)
0.1 0.8 GO:0071461 cellular response to redox state(GO:0071461)
0.1 1.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.9 GO:0045007 depurination(GO:0045007)
0.1 0.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.3 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 2.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 1.5 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.9 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 1.9 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.3 GO:0043095 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.1 0.7 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 0.7 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.3 GO:0097531 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 1.0 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 1.0 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.9 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 2.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.9 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.2 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.1 1.4 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 1.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.8 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.8 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.4 GO:1903998 regulation of eating behavior(GO:1903998)
0.1 0.7 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 1.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.6 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.2 GO:0061184 Spemann organizer formation(GO:0060061) positive regulation of dermatome development(GO:0061184)
0.1 1.0 GO:0061525 hindgut development(GO:0061525)
0.1 0.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 1.3 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.1 0.5 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.0 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.5 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.1 3.7 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.4 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.2 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.2 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 0.4 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.1 1.3 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.1 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 1.5 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.6 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.2 GO:0010562 positive regulation of phosphorus metabolic process(GO:0010562) positive regulation of phosphate metabolic process(GO:0045937)
0.1 1.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.4 GO:0015886 heme transport(GO:0015886)
0.1 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 1.8 GO:0042474 middle ear morphogenesis(GO:0042474)
0.1 3.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.1 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 5.3 GO:0035329 hippo signaling(GO:0035329)
0.1 1.0 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.9 GO:0000479 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 1.0 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 1.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 0.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.7 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 1.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.2 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
0.1 2.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 0.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.6 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 1.9 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 0.2 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 0.4 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.1 1.1 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 2.3 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 1.0 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 0.6 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.2 GO:2000977 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) regulation of forebrain neuron differentiation(GO:2000977)
0.1 0.7 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.3 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.6 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 2.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.5 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0 0.9 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.6 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.3 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.5 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 1.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 1.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.7 GO:0071897 DNA biosynthetic process(GO:0071897)
0.0 0.3 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.9 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 1.6 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.5 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.6 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 1.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.5 GO:0022604 regulation of cell morphogenesis(GO:0022604)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.0 GO:0071305 cellular response to vitamin D(GO:0071305)
0.0 0.6 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.6 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.5 GO:0015866 ADP transport(GO:0015866)
0.0 0.3 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.5 GO:0015074 DNA integration(GO:0015074)
0.0 0.7 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 1.1 GO:0036035 osteoclast development(GO:0036035)
0.0 0.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.3 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.9 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 2.8 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.5 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.3 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.4 GO:0006768 biotin metabolic process(GO:0006768)
0.0 1.5 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 1.2 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.5 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.5 GO:0010634 positive regulation of epithelial cell migration(GO:0010634)
0.0 0.4 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.0 0.7 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 3.5 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.5 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0001878 response to yeast(GO:0001878)
0.0 0.5 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 1.2 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.9 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) phagosome acidification(GO:0090383) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.5 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.5 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.5 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.0 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.6 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 4.6 GO:0021543 pallium development(GO:0021543)
0.0 0.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.1 GO:0031648 protein destabilization(GO:0031648)
0.0 0.5 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0 1.3 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.0 0.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 1.4 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.0 0.6 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.0 GO:1905098 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 1.2 GO:0045137 development of primary sexual characteristics(GO:0045137)
0.0 0.7 GO:0009268 response to pH(GO:0009268)
0.0 0.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 1.3 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.0 0.6 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.5 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.0 0.2 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.3 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 3.2 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.0 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0 0.5 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 3.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 2.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.5 GO:0048208 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 1.4 GO:0055072 iron ion homeostasis(GO:0055072)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.9 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.3 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.5 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 0.3 GO:0007596 blood coagulation(GO:0007596)
0.0 0.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.6 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 1.3 GO:0045333 cellular respiration(GO:0045333)
0.0 0.1 GO:2000078 columnar/cuboidal epithelial cell maturation(GO:0002069) glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560) positive regulation of type B pancreatic cell development(GO:2000078)
0.0 0.5 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.4 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.0 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 1.8 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.5 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 7.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.7 3.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.6 2.5 GO:0000811 GINS complex(GO:0000811)
0.5 1.6 GO:0035189 Rb-E2F complex(GO:0035189)
0.5 2.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.4 1.3 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.4 1.7 GO:1990742 microvesicle(GO:1990742)
0.4 2.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 2.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.3 1.0 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.3 5.0 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.3 1.9 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.3 5.5 GO:0031209 SCAR complex(GO:0031209)
0.3 1.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 1.2 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 0.7 GO:0032783 ELL-EAF complex(GO:0032783)
0.2 0.9 GO:0097629 extrinsic component of omegasome membrane(GO:0097629) extrinsic component of autophagosome membrane(GO:0097635)
0.2 0.7 GO:0008623 CHRAC(GO:0008623)
0.2 1.1 GO:0000938 GARP complex(GO:0000938)
0.2 0.6 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.2 0.6 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 3.0 GO:0042555 MCM complex(GO:0042555)
0.2 2.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 0.8 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.2 3.6 GO:0036038 MKS complex(GO:0036038)
0.2 1.9 GO:0061689 tricellular tight junction(GO:0061689)
0.2 0.8 GO:0002133 polycystin complex(GO:0002133)
0.1 0.7 GO:0031417 NatC complex(GO:0031417)
0.1 2.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 1.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.5 GO:0060187 cell pole(GO:0060187)
0.1 3.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 2.8 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.7 GO:0000796 condensin complex(GO:0000796)
0.1 0.5 GO:0045160 myosin I complex(GO:0045160)
0.1 0.9 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.3 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.1 0.3 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 2.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.4 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 1.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.1 0.7 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 3.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 2.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 1.0 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 1.9 GO:0000346 transcription export complex(GO:0000346)
0.1 2.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 7.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.5 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 1.3 GO:0045120 pronucleus(GO:0045120)
0.1 1.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 7.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 1.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.7 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.4 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.1 2.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 0.3 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.8 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 1.9 GO:0030904 retromer complex(GO:0030904)
0.1 1.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 3.2 GO:0097542 ciliary tip(GO:0097542)
0.0 3.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 2.2 GO:0030673 axolemma(GO:0030673)
0.0 1.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 2.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.9 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 3.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 1.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.2 GO:0031143 pseudopodium(GO:0031143)
0.0 4.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.5 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 4.3 GO:0005901 caveola(GO:0005901)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 3.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 3.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.5 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 1.6 GO:0030133 transport vesicle(GO:0030133)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.8 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 4.6 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.9 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 3.2 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 3.7 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.5 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 1.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 2.8 GO:0030496 midbody(GO:0030496)
0.0 0.3 GO:0099738 cell cortex region(GO:0099738)
0.0 0.5 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 1.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.3 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 1.2 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0097517 stress fiber(GO:0001725) actin filament bundle(GO:0032432) contractile actin filament bundle(GO:0097517)
0.0 0.9 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.8 GO:0016235 aggresome(GO:0016235)
0.0 0.9 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.4 GO:0042581 specific granule(GO:0042581)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
1.4 4.1 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
1.2 6.0 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.9 2.6 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.8 7.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.8 2.3 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.8 3.9 GO:0010736 serum response element binding(GO:0010736)
0.7 2.2 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.7 2.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.6 2.5 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.6 2.8 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.6 3.9 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.5 1.5 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.5 2.4 GO:0038025 reelin receptor activity(GO:0038025)
0.4 2.6 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.4 1.3 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.4 1.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.4 1.3 GO:0052831 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
0.4 1.2 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.4 1.2 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) V2 vasopressin receptor binding(GO:0031896)
0.4 2.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.3 1.0 GO:0008859 exoribonuclease II activity(GO:0008859)
0.3 0.9 GO:0080101 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.3 0.9 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.3 2.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.3 1.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.3 1.3 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.2 2.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 2.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 3.1 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.2 1.8 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.2 0.9 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.2 1.3 GO:0016213 linoleoyl-CoA desaturase activity(GO:0016213)
0.2 2.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.2 3.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 5.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.2 0.8 GO:0016662 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.2 2.5 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.2 0.8 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.2 2.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 0.6 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.2 0.8 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.2 0.6 GO:0036328 VEGF-C-activated receptor activity(GO:0036328)
0.2 0.9 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2 3.8 GO:0005542 folic acid binding(GO:0005542)
0.2 1.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.2 0.7 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.2 1.3 GO:0050815 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.2 0.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 0.6 GO:0032427 GBD domain binding(GO:0032427)
0.2 1.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.0 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 1.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.7 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 1.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 2.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 2.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.2 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 1.0 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.6 GO:0098808 mRNA cap binding(GO:0098808)
0.1 2.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.9 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 1.6 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.8 GO:0051373 FATZ binding(GO:0051373)
0.1 0.4 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.1 1.6 GO:0009881 photoreceptor activity(GO:0009881)
0.1 2.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 3.0 GO:0022840 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.1 1.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.1 0.9 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.4 GO:0047708 biotinidase activity(GO:0047708)
0.1 1.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.3 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.1 0.9 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.7 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 1.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183) vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 2.4 GO:0019841 retinol binding(GO:0019841)
0.1 0.5 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 1.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 3.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 1.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.9 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 1.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 1.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.8 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.9 GO:0004645 phosphorylase activity(GO:0004645)
0.1 0.3 GO:0051734 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.1 3.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.8 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 3.3 GO:0005109 frizzled binding(GO:0005109)
0.1 2.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.2 GO:0043295 glutathione binding(GO:0043295)
0.1 1.9 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.3 GO:0097677 STAT family protein binding(GO:0097677)
0.1 5.2 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.1 0.8 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.2 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 2.0 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 0.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.4 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.1 0.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 1.8 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.5 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 3.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.5 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 0.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 1.4 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.0 1.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.0 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.7 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.6 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.5 GO:0019238 cyclohydrolase activity(GO:0019238)
0.0 0.2 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.5 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 1.3 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 1.2 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.3 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 1.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.1 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.3 GO:0071253 connexin binding(GO:0071253)
0.0 0.5 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.5 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.7 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 2.6 GO:0008047 enzyme activator activity(GO:0008047)
0.0 4.1 GO:0017022 myosin binding(GO:0017022)
0.0 1.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.9 GO:0043495 protein anchor(GO:0043495)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 1.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 3.0 GO:0009055 electron carrier activity(GO:0009055)
0.0 1.5 GO:0030371 translation repressor activity(GO:0030371)
0.0 1.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 1.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.5 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 2.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 2.2 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0070402 NADPH binding(GO:0070402)
0.0 2.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 3.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 1.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 1.2 GO:0019843 rRNA binding(GO:0019843)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 1.7 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0022821 potassium ion antiporter activity(GO:0022821)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0042393 histone binding(GO:0042393)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.5 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.1 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 2.7 GO:0000149 SNARE binding(GO:0000149)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 2.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 3.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 3.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 9.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 5.7 PID AURORA A PATHWAY Aurora A signaling
0.1 3.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 2.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 0.5 PID IFNG PATHWAY IFN-gamma pathway
0.1 5.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 0.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 1.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.9 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 0.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 1.0 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.9 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 2.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.3 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 1.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.1 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 1.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 1.7 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 2.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 2.1 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.4 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.4 PID MTOR 4PATHWAY mTOR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.0 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 4.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.3 5.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.2 13.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 0.2 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.2 6.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.2 3.3 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.1 2.8 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 0.8 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 3.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 2.9 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 4.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.9 REACTOME OPSINS Genes involved in Opsins
0.1 1.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 1.0 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 3.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 1.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.6 REACTOME KINESINS Genes involved in Kinesins
0.1 2.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 2.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 0.9 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 3.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 2.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 2.9 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.3 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 7.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.2 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.6 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.0 1.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.9 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 1.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 2.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.6 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 1.0 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 2.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 2.5 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0 0.8 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 6.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.4 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters