ISMARA results: HMX2

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HMX2

Z-value: 0.49

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Transcription factors associated with HMX2

Gene Symbol	Gene ID	Gene Info
HMX2 Ensembl NCBI GeneCards UniProt	ENSG00000188816.3	H6 family homeobox 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HMX2	hg19_v2_chr10_+_124907638_124907660	0.15	5.3e-01	Click!

Activity profile of HMX2 motif

Sorted Z-values of HMX2 motif

No targets for HMX2

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	GO:0001778	plasma membrane repair(GO:0001778)
0.2	0.8	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.1	0.6	GO:0060166	olfactory pit development(GO:0060166)
0.1	0.6	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.1	0.5	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.5	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.1	0.4	GO:0006880	intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0	0.4	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.4	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.4	GO:0002227	innate immune response in mucosa(GO:0002227)

Showing 1 to 10 of 55 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.8	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.7	GO:0097228	sperm principal piece(GO:0097228)
0.0	0.7	GO:0000786	nucleosome(GO:0000786)
0.1	0.6	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.4	GO:0044326	dendritic spine neck(GO:0044326)
0.0	0.4	GO:0097470	ribbon synapse(GO:0097470)
0.1	0.3	GO:1990667	PCSK9-AnxA2 complex(GO:1990667)
0.0	0.3	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.3	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)

Showing 1 to 10 of 18 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.8	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.0	0.6	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.6	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.6	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.6	GO:0031369	translation initiation factor binding(GO:0031369)
0.0	0.5	GO:0008430	selenium binding(GO:0008430)
0.0	0.4	GO:0004883	glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0	0.4	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0	0.4	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.4	GO:0000150	recombinase activity(GO:0000150)

Showing 1 to 10 of 31 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.8	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.5	PID ARF 3PATHWAY	Arf1 pathway

Showing 1 to 2 of 2 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Total log-likelihood	Term	Description
0.9	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.8	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.7	REACTOME KINESINS	Genes involved in Kinesins
0.6	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway

Showing 1 to 5 of 5 entries

Results for HMX2

Z-value: 0.49

Motif logo

Transcription factors associated with HMX2

Activity-expression correlation:

Activity profile of HMX2 motif

Sorted Z-values of HMX2 motif

No targets for HMX2

Network of associatons between targets according to the STRING database.

First level regulatory network of HMX2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: