ISMARA results: HOMEZ

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOMEZ

Z-value: 1.61

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Transcription factors associated with HOMEZ

Gene Symbol	Gene ID	Gene Info
HOMEZ Ensembl NCBI GeneCards UniProt	ENSG00000215271.6	homeobox and leucine zipper encoding

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HOMEZ	hg19_v2_chr14_-_23762777_23762821	0.58	7.2e-03	Click!

Activity profile of HOMEZ motif

Sorted Z-values of HOMEZ motif

No targets for HOMEZ

Network of associatons between targets according to the STRING database.

First level regulatory network of HOMEZ

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	5.8	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	5.5	GO:0006368	transcription elongation from RNA polymerase II promoter(GO:0006368)
1.1	4.2	GO:0006428	isoleucyl-tRNA aminoacylation(GO:0006428)
0.4	3.9	GO:2001168	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1	3.2	GO:0003334	keratinocyte development(GO:0003334)
0.1	2.8	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.2	2.7	GO:0001778	plasma membrane repair(GO:0001778)
0.1	2.7	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	2.6	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.1	2.5	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)

Showing 1 to 10 of 210 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	5.4	GO:0045095	keratin filament(GO:0045095)
0.4	4.0	GO:0033503	HULC complex(GO:0033503)
0.2	3.9	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	3.7	GO:0002102	podosome(GO:0002102)
0.0	3.6	GO:0005901	caveola(GO:0005901)
0.6	3.4	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1	3.0	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	2.6	GO:0008180	COP9 signalosome(GO:0008180)
0.0	2.6	GO:0034399	nuclear periphery(GO:0034399)
0.1	2.5	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)

Showing 1 to 10 of 112 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.5	GO:0097110	scaffold protein binding(GO:0097110)
1.1	4.2	GO:0004822	isoleucine-tRNA ligase activity(GO:0004822)
0.0	3.9	GO:0002039	p53 binding(GO:0002039)
0.0	3.5	GO:0017137	Rab GTPase binding(GO:0017137)
0.1	3.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.1	3.2	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.1	3.0	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	2.6	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.4	2.5	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1	2.5	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)

Showing 1 to 10 of 153 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	11.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	5.6	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	3.8	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.1	3.5	PID BARD1 PATHWAY	BARD1 signaling events
0.0	3.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	2.6	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	2.2	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.0	1.8	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	1.6	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	1.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells

Showing 1 to 10 of 32 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	9.5	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.1	3.9	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
0.1	3.7	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.1	3.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	3.3	REACTOME PI METABOLISM	Genes involved in PI Metabolism
0.1	2.5	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	2.3	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	2.0	REACTOME PACKAGING OF TELOMERE ENDS	Genes involved in Packaging Of Telomere Ends
0.0	2.0	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.1	1.9	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha

Showing 1 to 10 of 58 entries

Results for HOMEZ

Z-value: 1.61

Motif logo

Transcription factors associated with HOMEZ

Activity-expression correlation:

Activity profile of HOMEZ motif

Sorted Z-values of HOMEZ motif

No targets for HOMEZ

Network of associatons between targets according to the STRING database.

First level regulatory network of HOMEZ

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: