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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOMEZ

Z-value: 1.61

Motif logo

Transcription factors associated with HOMEZ

Gene Symbol Gene ID Gene Info
ENSG00000215271.6 homeobox and leucine zipper encoding

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HOMEZhg19_v2_chr14_-_23762777_237628210.587.2e-03Click!

Activity profile of HOMEZ motif

Sorted Z-values of HOMEZ motif

Network of associatons between targets according to the STRING database.

First level regulatory network of HOMEZ

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.8 2.3 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.4 1.3 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.4 3.9 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.4 1.2 GO:0071048 nuclear mRNA surveillance of spliceosomal pre-mRNA splicing(GO:0071030) nuclear retention of unspliced pre-mRNA at the site of transcription(GO:0071048)
0.4 1.8 GO:0035519 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.4 1.5 GO:0006597 spermine biosynthetic process(GO:0006597)
0.4 1.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.3 1.7 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.3 1.3 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.3 1.5 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.3 1.1 GO:0052363 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.3 0.8 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.3 1.8 GO:0071461 cellular response to redox state(GO:0071461)
0.2 0.7 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.2 0.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.2 0.7 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.2 1.9 GO:0006741 NADP biosynthetic process(GO:0006741)
0.2 1.0 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.2 0.9 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 0.6 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.2 1.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.2 0.6 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 1.5 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 0.9 GO:0043686 co-translational protein modification(GO:0043686)
0.2 2.7 GO:0001778 plasma membrane repair(GO:0001778)
0.2 0.5 GO:0033320 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.2 0.7 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 2.0 GO:0032202 telomere assembly(GO:0032202)
0.2 1.0 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.2 1.0 GO:0071422 tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746) succinate transmembrane transport(GO:0071422)
0.2 0.9 GO:0018032 protein amidation(GO:0018032)
0.2 5.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.6 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.1 1.0 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.6 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.6 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.7 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 2.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.5 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 1.5 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 3.2 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.6 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.7 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.8 GO:1901377 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.1 2.7 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.5 GO:0016598 protein arginylation(GO:0016598)
0.1 0.3 GO:0032242 regulation of nucleoside transport(GO:0032242) positive regulation of necroptotic process(GO:0060545)
0.1 0.5 GO:0035397 helper T cell enhancement of adaptive immune response(GO:0035397)
0.1 0.7 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.7 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.3 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 2.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.5 GO:0050812 regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 0.7 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.5 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.1 0.5 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.1 2.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 1.0 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.5 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.8 GO:0048625 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.3 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.1 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.4 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.4 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 1.8 GO:0000338 protein deneddylation(GO:0000338)
0.1 0.5 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.1 1.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 1.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 1.6 GO:0090168 Golgi reassembly(GO:0090168)
0.1 0.7 GO:0009597 detection of virus(GO:0009597)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 1.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.8 GO:0051013 microtubule severing(GO:0051013)
0.1 0.5 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.1 0.4 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 0.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0033088 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.1 0.4 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.3 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.2 GO:0034471 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.1 1.2 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.5 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 1.0 GO:0048706 embryonic skeletal system development(GO:0048706)
0.1 1.0 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.3 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.3 GO:1990637 response to prolactin(GO:1990637)
0.1 0.4 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.5 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 0.2 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 1.2 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.5 GO:0048254 snoRNA localization(GO:0048254)
0.1 2.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.4 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.3 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.1 0.3 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.1 1.8 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.8 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.6 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 1.7 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.4 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.3 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:1904647 response to rotenone(GO:1904647)
0.0 2.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 2.0 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.9 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.3 GO:0010994 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.0 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.7 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.4 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.4 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.0 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.9 GO:0006853 carnitine shuttle(GO:0006853)
0.0 1.3 GO:0014829 vascular smooth muscle contraction(GO:0014829)
0.0 0.3 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 1.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.3 GO:1903750 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481) positive regulation of MHC class I biosynthetic process(GO:0045345) regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.0 0.2 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 5.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.9 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.9 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.6 GO:0051451 myoblast migration(GO:0051451)
0.0 0.4 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 1.2 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.5 GO:2000674 regulation of type B pancreatic cell apoptotic process(GO:2000674) negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.5 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.0 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.8 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.3 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 1.6 GO:0032400 melanosome localization(GO:0032400)
0.0 1.2 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.3 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.3 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.4 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 1.2 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 1.5 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.8 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0009183 purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.0 0.1 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.5 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.7 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.5 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 2.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:1905229 cellular response to glycoprotein(GO:1904588) cellular response to thyrotropin-releasing hormone(GO:1905229)
0.0 0.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.7 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.9 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.5 GO:0001895 retina homeostasis(GO:0001895)
0.0 0.5 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.0 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0 0.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.0 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 1.7 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.4 GO:0003416 endochondral bone growth(GO:0003416) positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.0 0.2 GO:0007030 Golgi organization(GO:0007030)
0.0 0.0 GO:0050823 peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.0 0.2 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.8 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.6 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.1 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0 0.6 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.4 GO:0045124 regulation of bone resorption(GO:0045124)
0.0 0.3 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.1 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 1.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.1 GO:0045921 positive regulation of exocytosis(GO:0045921)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.4 4.0 GO:0033503 HULC complex(GO:0033503)
0.3 2.0 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.3 1.2 GO:0071020 post-spliceosomal complex(GO:0071020)
0.2 0.7 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.2 1.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.2 1.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 2.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 1.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.2 3.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 2.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 0.5 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2 1.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.9 GO:0097149 centralspindlin complex(GO:0097149)
0.1 1.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.4 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.5 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.1 0.6 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.1 0.3 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.1 2.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 0.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 1.5 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.1 GO:0034464 BBSome(GO:0034464)
0.1 3.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.4 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.5 GO:0030891 VCB complex(GO:0030891)
0.1 5.4 GO:0045095 keratin filament(GO:0045095)
0.1 0.8 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 1.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.8 GO:0000796 condensin complex(GO:0000796)
0.1 1.0 GO:0097470 ribbon synapse(GO:0097470)
0.1 0.5 GO:0071203 WASH complex(GO:0071203)
0.1 0.6 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.1 1.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.5 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.1 2.3 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 0.7 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.0 GO:0044754 autolysosome(GO:0044754)
0.1 0.7 GO:0000322 storage vacuole(GO:0000322)
0.0 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 3.7 GO:0002102 podosome(GO:0002102)
0.0 0.8 GO:0001741 XY body(GO:0001741)
0.0 2.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 1.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 2.6 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 1.2 GO:0097386 glial cell projection(GO:0097386)
0.0 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.4 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.7 GO:0030897 HOPS complex(GO:0030897)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.9 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 1.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 1.0 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 3.6 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.3 GO:0005605 basal lamina(GO:0005605)
0.0 1.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.3 GO:0043203 axon hillock(GO:0043203)
0.0 0.9 GO:0005770 late endosome(GO:0005770)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:0005694 chromosome(GO:0005694)
0.0 0.1 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.5 GO:0097342 ripoptosome(GO:0097342)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.0 GO:0034657 GID complex(GO:0034657)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.7 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 1.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 2.6 GO:0034399 nuclear periphery(GO:0034399)
0.0 1.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.4 GO:0030686 90S preribosome(GO:0030686)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.0 GO:0036064 ciliary basal body(GO:0036064)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.5 1.5 GO:0016768 spermine synthase activity(GO:0016768)
0.4 1.5 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.4 2.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.4 1.4 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.3 1.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.3 0.8 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.3 0.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.7 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.2 1.2 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.2 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 1.5 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.2 0.7 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.2 0.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.5 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.2 1.0 GO:0017153 citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.2 0.9 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.2 0.6 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.1 1.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 2.3 GO:0008517 folic acid transporter activity(GO:0008517)
0.1 0.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.6 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 1.8 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 2.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.3 GO:0045545 syndecan binding(GO:0045545)
0.1 0.4 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.1 1.2 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 2.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.5 GO:0004057 arginyltransferase activity(GO:0004057)
0.1 2.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1 1.0 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.3 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.5 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.5 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.1 3.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.1 0.5 GO:0003883 CTP synthase activity(GO:0003883)
0.1 0.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 1.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.1 0.4 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.8 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.3 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 0.5 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.7 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 3.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.6 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 0.3 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.2 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 6.5 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.8 GO:0042731 PH domain binding(GO:0042731)
0.1 1.0 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.0 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 3.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.8 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.5 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.4 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 1.0 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 1.9 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 2.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0098625 methylselenol reductase activity(GO:0098625) methylseleninic acid reductase activity(GO:0098626)
0.0 0.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.7 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.0 1.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 2.1 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.6 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 3.9 GO:0002039 p53 binding(GO:0002039)
0.0 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 1.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 2.2 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.3 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.4 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.7 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.6 GO:0030515 snoRNA binding(GO:0030515)
0.0 1.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 2.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.3 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 3.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.8 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.2 GO:0035497 cAMP response element binding(GO:0035497)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 11.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 5.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 3.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 3.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 3.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 1.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 2.2 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 1.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.9 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.9 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 1.0 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.8 PID P73PATHWAY p73 transcription factor network
0.0 1.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 3.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 3.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 1.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.7 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 0.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 1.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.0 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.7 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 1.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 3.3 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.0 0.9 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 2.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.6 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 1.4 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.0 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 1.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 1.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.7 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.0 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.6 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 9.5 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.7 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.3 REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 2.0 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway