Project
avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for HOXB4_LHX9
Z-value: 3.67
Motif logo
Transcription factors associated with HOXB4_LHX9
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HOXB4
|
ENSG00000182742.5 | homeobox B4 |
|
LHX9
|
ENSG00000143355.11 | LIM homeobox 9 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| LHX9 | hg19_v2_chr1_+_197881592_197881635 | -0.81 | 1.5e-05 | Click! |
| HOXB4 | hg19_v2_chr17_-_46657473_46657473 | 0.52 | 1.9e-02 | Click! |
Activity profile of HOXB4_LHX9 motif
Sorted Z-values of HOXB4_LHX9 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXB4_LHX9
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.3 | 31.5 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 3.0 | 9.0 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 2.5 | 27.2 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
| 1.9 | 5.8 | GO:0060489 | orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
| 1.5 | 54.9 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 1.5 | 10.5 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 1.4 | 6.8 | GO:0043553 | vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 1.1 | 4.6 | GO:0010983 | positive regulation of high-density lipoprotein particle clearance(GO:0010983) |
| 1.0 | 4.0 | GO:0035188 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 1.0 | 4.0 | GO:0051541 | elastin metabolic process(GO:0051541) |
| 1.0 | 3.0 | GO:0019364 | NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364) |
| 0.9 | 8.4 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.9 | 2.8 | GO:1903676 | regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676) |
| 0.9 | 6.4 | GO:0038172 | interleukin-33-mediated signaling pathway(GO:0038172) |
| 0.9 | 14.1 | GO:0042420 | dopamine catabolic process(GO:0042420) |
| 0.9 | 4.3 | GO:0045914 | negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470) |
| 0.8 | 5.7 | GO:1903575 | cornified envelope assembly(GO:1903575) |
| 0.8 | 2.4 | GO:0097198 | histone H3-K36 trimethylation(GO:0097198) |
| 0.7 | 6.3 | GO:1903265 | positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) |
| 0.6 | 4.5 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.6 | 2.5 | GO:0043456 | regulation of pentose-phosphate shunt(GO:0043456) |
| 0.6 | 5.0 | GO:0006880 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.6 | 4.0 | GO:0051697 | protein delipidation(GO:0051697) |
| 0.6 | 8.5 | GO:0019317 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.6 | 2.8 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.5 | 4.6 | GO:2001206 | positive regulation of osteoclast development(GO:2001206) |
| 0.5 | 2.6 | GO:0046092 | deoxycytidine metabolic process(GO:0046092) |
| 0.5 | 3.0 | GO:1904207 | regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209) |
| 0.5 | 3.0 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 0.4 | 7.2 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.4 | 1.8 | GO:0031455 | glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456) |
| 0.4 | 10.7 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.4 | 1.5 | GO:0034344 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) positive regulation of interferon-alpha biosynthetic process(GO:0045356) |
| 0.4 | 1.5 | GO:0019859 | pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) |
| 0.4 | 1.8 | GO:0052250 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
| 0.4 | 9.2 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.4 | 6.8 | GO:0046007 | negative regulation of activated T cell proliferation(GO:0046007) |
| 0.4 | 1.8 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 0.4 | 2.5 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.3 | 1.0 | GO:1904956 | regulation of midbrain dopaminergic neuron differentiation(GO:1904956) |
| 0.3 | 1.7 | GO:0070980 | biphenyl catabolic process(GO:0070980) |
| 0.3 | 1.7 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.3 | 1.3 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.3 | 2.5 | GO:1901295 | positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
| 0.3 | 1.5 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.3 | 3.7 | GO:0090646 | mitochondrial tRNA processing(GO:0090646) |
| 0.3 | 3.2 | GO:0019367 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.3 | 1.3 | GO:0035513 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
| 0.3 | 2.3 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.2 | 1.5 | GO:1904383 | response to sodium phosphate(GO:1904383) |
| 0.2 | 4.0 | GO:0097475 | motor neuron migration(GO:0097475) |
| 0.2 | 11.5 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
| 0.2 | 1.4 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.2 | 2.3 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.2 | 0.9 | GO:0070318 | positive regulation of G0 to G1 transition(GO:0070318) |
| 0.2 | 0.9 | GO:0052362 | multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419) |
| 0.2 | 2.4 | GO:0070973 | protein localization to endoplasmic reticulum exit site(GO:0070973) |
| 0.2 | 3.9 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.2 | 10.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.2 | 4.2 | GO:0014870 | response to muscle inactivity(GO:0014870) |
| 0.2 | 0.5 | GO:0002476 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) |
| 0.2 | 3.9 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.2 | 5.2 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.2 | 1.3 | GO:0098967 | exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967) |
| 0.2 | 3.5 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.2 | 1.4 | GO:1900625 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
| 0.2 | 3.6 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.2 | 7.7 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.2 | 1.2 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 0.7 | GO:2000521 | negative regulation of immunological synapse formation(GO:2000521) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189) |
| 0.1 | 6.1 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.1 | 1.7 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.1 | 8.1 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.1 | 2.7 | GO:0010992 | ubiquitin homeostasis(GO:0010992) |
| 0.1 | 1.1 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 0.1 | 6.0 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.1 | 1.5 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.1 | 3.9 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 0.5 | GO:0032053 | ciliary basal body organization(GO:0032053) |
| 0.1 | 4.8 | GO:0048012 | hepatocyte growth factor receptor signaling pathway(GO:0048012) |
| 0.1 | 0.7 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
| 0.1 | 1.0 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.1 | 2.0 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.1 | 2.7 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.1 | 1.3 | GO:0032224 | positive regulation of synaptic transmission, cholinergic(GO:0032224) |
| 0.1 | 3.8 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.1 | 2.3 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 2.3 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.1 | 1.2 | GO:0098814 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.1 | 0.4 | GO:0046338 | phosphatidylethanolamine catabolic process(GO:0046338) |
| 0.1 | 2.6 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.1 | 1.3 | GO:0018243 | protein O-linked glycosylation via threonine(GO:0018243) |
| 0.1 | 2.5 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.1 | 0.4 | GO:0043324 | eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474) |
| 0.1 | 1.5 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.1 | 3.3 | GO:0015991 | ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.1 | 1.2 | GO:1900112 | regulation of histone H3-K9 trimethylation(GO:1900112) |
| 0.1 | 1.5 | GO:0048739 | cardiac muscle fiber development(GO:0048739) |
| 0.1 | 2.0 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 0.1 | 2.6 | GO:0000042 | protein targeting to Golgi(GO:0000042) |
| 0.1 | 0.3 | GO:0009597 | detection of virus(GO:0009597) |
| 0.1 | 1.7 | GO:0008285 | negative regulation of cell proliferation(GO:0008285) |
| 0.1 | 0.8 | GO:0098856 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.1 | 3.5 | GO:0006458 | 'de novo' protein folding(GO:0006458) |
| 0.1 | 2.6 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.1 | 9.4 | GO:0010508 | positive regulation of autophagy(GO:0010508) |
| 0.1 | 9.6 | GO:0070268 | cornification(GO:0070268) |
| 0.1 | 1.6 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) chaperone-mediated protein complex assembly(GO:0051131) |
| 0.1 | 4.4 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.1 | 0.4 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
| 0.1 | 1.0 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.1 | 2.7 | GO:0006515 | misfolded or incompletely synthesized protein catabolic process(GO:0006515) |
| 0.1 | 0.5 | GO:0030242 | pexophagy(GO:0030242) |
| 0.0 | 1.4 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 0.0 | 0.3 | GO:0052565 | response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565) |
| 0.0 | 0.2 | GO:1904798 | positive regulation of core promoter binding(GO:1904798) |
| 0.0 | 1.0 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.0 | 2.6 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.6 | GO:0015727 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.0 | 1.7 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.8 | GO:0072643 | interferon-gamma secretion(GO:0072643) |
| 0.0 | 0.3 | GO:1903826 | arginine transmembrane transport(GO:1903826) |
| 0.0 | 4.3 | GO:0042035 | regulation of cytokine biosynthetic process(GO:0042035) |
| 0.0 | 0.5 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.0 | 0.2 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.0 | 5.4 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
| 0.0 | 1.7 | GO:0016577 | histone demethylation(GO:0016577) |
| 0.0 | 0.7 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.0 | 1.3 | GO:0045730 | respiratory burst(GO:0045730) |
| 0.0 | 0.2 | GO:0048842 | positive regulation of axon extension involved in axon guidance(GO:0048842) |
| 0.0 | 1.1 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
| 0.0 | 0.4 | GO:0051096 | positive regulation of helicase activity(GO:0051096) |
| 0.0 | 5.0 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 2.7 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.2 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.0 | 0.3 | GO:2000622 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.0 | 1.7 | GO:1904837 | beta-catenin-TCF complex assembly(GO:1904837) |
| 0.0 | 3.1 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 2.4 | GO:0007588 | excretion(GO:0007588) |
| 0.0 | 1.1 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 0.1 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 0.0 | 0.9 | GO:0051764 | actin crosslink formation(GO:0051764) |
| 0.0 | 1.3 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.0 | 3.4 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 1.5 | GO:0061053 | somite development(GO:0061053) |
| 0.0 | 0.8 | GO:0060285 | cilium-dependent cell motility(GO:0060285) |
| 0.0 | 1.6 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.0 | 0.5 | GO:2000010 | positive regulation of protein localization to cell surface(GO:2000010) |
| 0.0 | 3.4 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 0.3 | GO:2000726 | negative regulation of cardiac muscle cell differentiation(GO:2000726) |
| 0.0 | 1.4 | GO:0030032 | lamellipodium assembly(GO:0030032) |
| 0.0 | 0.6 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.2 | GO:0098719 | sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.0 | 7.1 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
| 0.0 | 3.1 | GO:0019722 | calcium-mediated signaling(GO:0019722) |
| 0.0 | 0.4 | GO:0006833 | water transport(GO:0006833) |
| 0.0 | 0.1 | GO:0014717 | regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901) |
| 0.0 | 6.9 | GO:0031346 | positive regulation of cell projection organization(GO:0031346) |
| 0.0 | 2.0 | GO:0098869 | cellular oxidant detoxification(GO:0098869) |
| 0.0 | 0.8 | GO:0002763 | positive regulation of myeloid leukocyte differentiation(GO:0002763) |
| 0.0 | 1.0 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.4 | GO:0031468 | nuclear envelope reassembly(GO:0031468) |
| 0.0 | 0.3 | GO:1902895 | positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895) |
| 0.0 | 2.4 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.0 | 1.6 | GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433) |
| 0.0 | 0.4 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.1 | GO:2000628 | regulation of miRNA metabolic process(GO:2000628) |
| 0.0 | 1.1 | GO:0048207 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.0 | 1.1 | GO:0002456 | T cell mediated immunity(GO:0002456) |
| 0.0 | 0.2 | GO:2000479 | regulation of cAMP-dependent protein kinase activity(GO:2000479) |
| 0.0 | 0.2 | GO:0016255 | attachment of GPI anchor to protein(GO:0016255) |
| 0.0 | 0.6 | GO:0032755 | positive regulation of interleukin-6 production(GO:0032755) |
| 0.0 | 1.4 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 0.0 | 5.2 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 0.0 | 1.3 | GO:0003333 | amino acid transmembrane transport(GO:0003333) |
| 0.0 | 1.4 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.0 | 0.6 | GO:0007219 | Notch signaling pathway(GO:0007219) |
| 0.0 | 0.2 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 9.1 | 27.2 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
| 2.3 | 6.8 | GO:1990032 | parallel fiber(GO:1990032) |
| 1.5 | 47.4 | GO:0030056 | hemidesmosome(GO:0030056) |
| 1.4 | 5.8 | GO:0060187 | cell pole(GO:0060187) |
| 0.7 | 6.3 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
| 0.7 | 7.5 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.6 | 5.0 | GO:0044326 | dendritic spine neck(GO:0044326) |
| 0.5 | 8.4 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.5 | 11.2 | GO:0043203 | axon hillock(GO:0043203) |
| 0.5 | 3.7 | GO:0030678 | mitochondrial ribonuclease P complex(GO:0030678) |
| 0.5 | 6.9 | GO:0030478 | actin cap(GO:0030478) |
| 0.4 | 36.8 | GO:0045178 | basal part of cell(GO:0045178) |
| 0.3 | 3.8 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.3 | 8.1 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.3 | 2.6 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.3 | 1.3 | GO:1990796 | photoreceptor cell terminal bouton(GO:1990796) |
| 0.3 | 5.2 | GO:0033180 | proton-transporting V-type ATPase, V1 domain(GO:0033180) |
| 0.3 | 0.9 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.3 | 2.9 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.3 | 1.7 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.3 | 1.1 | GO:1902912 | pyruvate kinase complex(GO:1902912) |
| 0.3 | 2.5 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.3 | 6.8 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.2 | 3.9 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.2 | 2.2 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.2 | 6.1 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.2 | 3.0 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.2 | 1.0 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.2 | 7.9 | GO:0030057 | desmosome(GO:0030057) |
| 0.2 | 1.1 | GO:1990131 | Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.2 | 8.2 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.2 | 0.9 | GO:1990667 | PCSK9-AnxA2 complex(GO:1990667) |
| 0.2 | 7.2 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 1.8 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 10.7 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 0.7 | GO:0031417 | NatC complex(GO:0031417) |
| 0.1 | 2.3 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.1 | 3.8 | GO:0036020 | endolysosome membrane(GO:0036020) |
| 0.1 | 3.2 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) IkappaB kinase complex(GO:0008385) |
| 0.1 | 1.7 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 1.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 2.6 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.1 | 1.5 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.1 | 4.3 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 4.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 9.1 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 2.5 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.1 | 1.9 | GO:0032433 | filopodium tip(GO:0032433) |
| 0.1 | 0.3 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 0.1 | 0.5 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.1 | 5.7 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.1 | 0.5 | GO:0042825 | TAP complex(GO:0042825) |
| 0.1 | 3.1 | GO:0005921 | gap junction(GO:0005921) |
| 0.1 | 10.4 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 3.2 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.1 | 0.4 | GO:1990730 | VCP-NSFL1C complex(GO:1990730) |
| 0.1 | 1.7 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 0.3 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.1 | 0.4 | GO:0002177 | manchette(GO:0002177) |
| 0.1 | 0.3 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 0.1 | 3.5 | GO:1904115 | axon cytoplasm(GO:1904115) |
| 0.1 | 0.2 | GO:0036027 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 0.1 | 4.8 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 1.4 | GO:0097517 | stress fiber(GO:0001725) actin filament bundle(GO:0032432) contractile actin filament bundle(GO:0097517) |
| 0.0 | 5.2 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 10.6 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 1.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 1.2 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.0 | 1.3 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 1.4 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 11.0 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 0.4 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.0 | 0.2 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
| 0.0 | 4.5 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 1.7 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 11.2 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 4.6 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 5.2 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 3.6 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.0 | 1.6 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 2.7 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 3.9 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 2.8 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 0.9 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 7.5 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.4 | GO:0033162 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
| 0.0 | 1.1 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 3.4 | GO:0000785 | chromatin(GO:0000785) |
| 0.0 | 1.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 1.1 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 0.8 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.6 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.6 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 1.3 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 6.6 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.5 | GO:0001772 | immunological synapse(GO:0001772) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 31.5 | GO:1990254 | keratin filament binding(GO:1990254) |
| 2.1 | 6.4 | GO:0002113 | interleukin-33 binding(GO:0002113) |
| 1.6 | 14.1 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 1.2 | 4.6 | GO:0010348 | lithium:proton antiporter activity(GO:0010348) |
| 1.0 | 6.8 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 0.9 | 4.3 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 0.8 | 4.2 | GO:0052829 | inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) |
| 0.8 | 11.5 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
| 0.7 | 2.7 | GO:0016005 | phospholipase A2 activator activity(GO:0016005) |
| 0.7 | 2.6 | GO:0008281 | sulfonylurea receptor activity(GO:0008281) |
| 0.6 | 2.6 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
| 0.6 | 2.5 | GO:0004082 | bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538) |
| 0.6 | 3.5 | GO:0047006 | 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) |
| 0.6 | 1.7 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.6 | 2.8 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.5 | 2.5 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 0.5 | 1.4 | GO:0015432 | bile acid-exporting ATPase activity(GO:0015432) |
| 0.4 | 8.5 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.4 | 3.5 | GO:0000285 | 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285) |
| 0.4 | 2.6 | GO:0004137 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 0.4 | 2.0 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.4 | 9.2 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.3 | 2.7 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.3 | 2.3 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 0.3 | 1.6 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
| 0.3 | 4.4 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.3 | 3.1 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.3 | 1.2 | GO:0008260 | 3-oxoacid CoA-transferase activity(GO:0008260) |
| 0.3 | 2.1 | GO:0070728 | leucine binding(GO:0070728) |
| 0.3 | 6.8 | GO:0008603 | cAMP-dependent protein kinase regulator activity(GO:0008603) |
| 0.3 | 3.2 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.3 | 1.3 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
| 0.3 | 6.3 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.2 | 0.9 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.2 | 2.0 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.2 | 3.8 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.2 | 1.5 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.2 | 3.7 | GO:0004526 | ribonuclease P activity(GO:0004526) |
| 0.2 | 6.9 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.2 | 4.0 | GO:0000014 | single-stranded DNA endodeoxyribonuclease activity(GO:0000014) |
| 0.2 | 2.0 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 0.2 | 1.8 | GO:0089720 | caspase binding(GO:0089720) |
| 0.2 | 1.1 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
| 0.2 | 21.5 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.2 | 3.0 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.2 | 5.7 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.2 | 1.9 | GO:0060002 | plus-end directed microfilament motor activity(GO:0060002) |
| 0.2 | 8.4 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.2 | 1.6 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.2 | 7.1 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.2 | 2.9 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.2 | 5.2 | GO:0046961 | proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.1 | 5.1 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.1 | 0.7 | GO:0019863 | IgE binding(GO:0019863) |
| 0.1 | 1.3 | GO:0050544 | arachidonic acid binding(GO:0050544) |
| 0.1 | 0.4 | GO:0072544 | L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544) |
| 0.1 | 3.0 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 0.5 | GO:0015433 | peptide antigen-transporting ATPase activity(GO:0015433) |
| 0.1 | 5.0 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.1 | 5.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 4.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 6.1 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.1 | 3.9 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 5.1 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 2.1 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.1 | 2.3 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 0.8 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.1 | 2.3 | GO:0098748 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 4.5 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 1.0 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.1 | 0.3 | GO:0008466 | glycogenin glucosyltransferase activity(GO:0008466) |
| 0.1 | 1.9 | GO:0000062 | fatty-acyl-CoA binding(GO:0000062) |
| 0.1 | 1.7 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.1 | 0.8 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.1 | 11.6 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 0.4 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.1 | 8.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 1.2 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.1 | 0.3 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 0.1 | 3.4 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.1 | 1.8 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.1 | 1.0 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.0 | 4.4 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.3 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.6 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.0 | 1.7 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 1.3 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.0 | 0.7 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 1.3 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 13.8 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.0 | 5.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 4.4 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 2.2 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.0 | 3.2 | GO:0017022 | myosin binding(GO:0017022) |
| 0.0 | 3.9 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 1.4 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 2.0 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.0 | 0.8 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 0.3 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
| 0.0 | 11.6 | GO:0060090 | binding, bridging(GO:0060090) |
| 0.0 | 9.8 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.2 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
| 0.0 | 1.7 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 4.4 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
| 0.0 | 5.5 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
| 0.0 | 1.5 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.0 | 0.6 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 0.9 | GO:0008484 | sulfuric ester hydrolase activity(GO:0008484) |
| 0.0 | 0.4 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.0 | 0.9 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 0.4 | GO:0015250 | water channel activity(GO:0015250) |
| 0.0 | 0.6 | GO:0046914 | transition metal ion binding(GO:0046914) |
| 0.0 | 0.3 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 0.8 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.0 | 1.0 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.2 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.0 | 4.1 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 5.1 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.0 | 1.4 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 1.7 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 2.1 | GO:0019903 | protein phosphatase binding(GO:0019903) |
| 0.0 | 0.1 | GO:0035197 | siRNA binding(GO:0035197) |
| 0.0 | 1.7 | GO:0016779 | nucleotidyltransferase activity(GO:0016779) |
| 0.0 | 4.8 | GO:0003723 | RNA binding(GO:0003723) |
| 0.0 | 1.6 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 49.7 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.7 | 27.2 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.3 | 8.5 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.3 | 31.5 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 10.2 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.1 | 6.2 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.1 | 8.4 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 8.9 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 2.7 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 7.5 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.1 | 5.1 | PID NEPHRIN NEPH1 PATHWAY | Nephrin/Neph1 signaling in the kidney podocyte |
| 0.1 | 0.7 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.1 | 4.3 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 1.9 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 3.1 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.1 | 4.8 | PID FOXO PATHWAY | FoxO family signaling |
| 0.1 | 1.4 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 0.1 | 6.8 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 3.9 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 1.3 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.1 | 2.0 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.1 | 6.0 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 3.7 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 5.3 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 12.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 1.3 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 1.6 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 2.0 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.3 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.0 | 1.5 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 2.3 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.0 | 1.2 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 1.1 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 1.2 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 0.9 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 14.1 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 0.6 | 49.9 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.4 | 9.4 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.3 | 3.2 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.2 | 10.2 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.2 | 6.7 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.2 | 4.2 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.2 | 1.5 | REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX | Genes involved in TRAF6 mediated induction of TAK1 complex |
| 0.1 | 23.9 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 6.8 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.1 | 2.3 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.1 | 4.0 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.1 | 4.7 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.1 | 2.3 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.1 | 2.2 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.1 | 6.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 8.4 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 3.2 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.1 | 2.6 | REACTOME G1 S SPECIFIC TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
| 0.1 | 2.3 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 1.4 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.1 | 0.9 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.1 | 0.8 | REACTOME ADP SIGNALLING THROUGH P2RY1 | Genes involved in ADP signalling through P2Y purinoceptor 1 |
| 0.1 | 1.6 | REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 1.4 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.1 | 5.7 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.1 | 1.7 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 1.3 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.1 | 1.3 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 1.4 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.0 | 2.7 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 2.5 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 2.5 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.0 | 4.3 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.0 | 2.6 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.0 | 1.9 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 1.3 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 1.7 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 0.4 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 1.7 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 3.7 | REACTOME CELL JUNCTION ORGANIZATION | Genes involved in Cell junction organization |
| 0.0 | 0.9 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.0 | 1.3 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.7 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.1 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.0 | 0.3 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.4 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 0.0 | 0.4 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 0.2 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.0 | 1.1 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |