ISMARA results: HOXB5

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HOXB5

Z-value: 0.75

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Transcription factors associated with HOXB5

Gene Symbol	Gene ID	Gene Info
HOXB5 Ensembl NCBI GeneCards UniProt	ENSG00000120075.5	homeobox B5

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HOXB5	hg19_v2_chr17_-_46671323_46671323	0.79	3.3e-05	Click!

Activity profile of HOXB5 motif

Sorted Z-values of HOXB5 motif

No targets for HOXB5

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB5

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	3.7	GO:1901642	nucleoside transmembrane transport(GO:1901642)
0.2	3.6	GO:0006228	UTP biosynthetic process(GO:0006228)
0.7	2.9	GO:0042377	menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1	1.8	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.1	1.8	GO:0042776	mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0	1.2	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.1	0.9	GO:0019348	dolichol metabolic process(GO:0019348)
0.1	0.9	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.1	0.7	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.0	0.7	GO:0035641	locomotory exploration behavior(GO:0035641)

Showing 1 to 10 of 29 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.8	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1	1.8	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1	1.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.2	0.9	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	0.9	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.6	GO:0032433	filopodium tip(GO:0032433)
0.0	0.2	GO:0042825	TAP complex(GO:0042825)
0.0	0.2	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)

Showing 1 to 9 of 9 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	3.7	GO:0008504	monoamine transmembrane transporter activity(GO:0008504)
0.1	3.6	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
0.1	3.5	GO:0005504	fatty acid binding(GO:0005504)
0.1	1.8	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	1.8	GO:0017075	syntaxin-1 binding(GO:0017075)
0.2	0.9	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1	0.9	GO:0030621	U4 snRNA binding(GO:0030621)
0.2	0.7	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
0.2	0.6	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.1	0.5	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923)

Showing 1 to 10 of 21 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	PID TRAIL PATHWAY	TRAIL signaling pathway

Showing 1 to 1 of 1 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.7	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1	1.8	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.1	0.9	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.8	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.4	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs

Showing 1 to 5 of 5 entries

Results for HOXB5

Z-value: 0.75

Motif logo

Transcription factors associated with HOXB5

Activity-expression correlation:

Activity profile of HOXB5 motif

Sorted Z-values of HOXB5 motif

No targets for HOXB5

Network of associatons between targets according to the STRING database.

First level regulatory network of HOXB5

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: