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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for HOXC10_HOXD13
Z-value: 2.97
Motif logo
Transcription factors associated with HOXC10_HOXD13
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
HOXC10
|
ENSG00000180818.4 | homeobox C10 |
|
HOXD13
|
ENSG00000128714.5 | homeobox D13 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| HOXC10 | hg19_v2_chr12_+_54378923_54378970 | -0.97 | 5.4e-13 | Click! |
| HOXD13 | hg19_v2_chr2_+_176957619_176957619 | -0.73 | 2.8e-04 | Click! |
Activity profile of HOXC10_HOXD13 motif
Sorted Z-values of HOXC10_HOXD13 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of HOXC10_HOXD13
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.5 | 16.4 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
| 4.6 | 13.8 | GO:0070175 | positive regulation of enamel mineralization(GO:0070175) |
| 2.3 | 6.9 | GO:1904237 | regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237) |
| 1.7 | 5.0 | GO:0060278 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 1.7 | 6.7 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 1.6 | 4.8 | GO:0043449 | cellular alkene metabolic process(GO:0043449) |
| 1.1 | 7.6 | GO:0010046 | response to mycotoxin(GO:0010046) |
| 1.0 | 2.9 | GO:0060490 | orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) |
| 0.9 | 4.5 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.7 | 5.4 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.6 | 8.6 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
| 0.5 | 3.5 | GO:0032445 | fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 0.5 | 2.5 | GO:0039534 | negative regulation of MDA-5 signaling pathway(GO:0039534) |
| 0.5 | 1.4 | GO:0002514 | B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) |
| 0.5 | 1.4 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
| 0.5 | 2.3 | GO:0032571 | response to vitamin K(GO:0032571) |
| 0.4 | 2.7 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 0.4 | 1.7 | GO:0002384 | hepatic immune response(GO:0002384) |
| 0.4 | 2.1 | GO:0003051 | angiotensin-mediated drinking behavior(GO:0003051) receptor-mediated virion attachment to host cell(GO:0046813) |
| 0.4 | 1.7 | GO:2000097 | regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.4 | 1.5 | GO:0001835 | blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684) |
| 0.4 | 1.1 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.4 | 1.9 | GO:0021622 | optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623) |
| 0.4 | 2.2 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.4 | 2.2 | GO:0001555 | oocyte growth(GO:0001555) |
| 0.4 | 7.1 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.3 | 4.5 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.3 | 3.1 | GO:1902035 | positive regulation of hematopoietic stem cell proliferation(GO:1902035) |
| 0.3 | 21.4 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.3 | 7.8 | GO:0006704 | glucocorticoid biosynthetic process(GO:0006704) |
| 0.3 | 3.3 | GO:1901315 | negative regulation of histone ubiquitination(GO:0033183) progesterone receptor signaling pathway(GO:0050847) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) |
| 0.3 | 1.9 | GO:0001692 | histamine metabolic process(GO:0001692) |
| 0.3 | 0.3 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.3 | 1.2 | GO:0007403 | glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) |
| 0.3 | 2.4 | GO:0070649 | polar body extrusion after meiotic divisions(GO:0040038) formin-nucleated actin cable assembly(GO:0070649) |
| 0.3 | 5.4 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.3 | 0.8 | GO:0061394 | regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) |
| 0.3 | 1.7 | GO:0033489 | cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490) |
| 0.3 | 1.4 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.3 | 0.8 | GO:1903515 | calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515) |
| 0.3 | 1.1 | GO:0035905 | N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) |
| 0.3 | 3.0 | GO:0070779 | gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.3 | 1.3 | GO:0036414 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 0.2 | 1.6 | GO:1904996 | positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996) |
| 0.2 | 5.5 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.2 | 1.0 | GO:2000639 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
| 0.2 | 5.1 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
| 0.2 | 1.0 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
| 0.2 | 3.8 | GO:0006183 | GTP biosynthetic process(GO:0006183) |
| 0.2 | 0.8 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.2 | 2.8 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 0.2 | 1.6 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) |
| 0.2 | 1.4 | GO:2000795 | negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.2 | 2.5 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.2 | 1.0 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.2 | 13.5 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.2 | 1.0 | GO:0001781 | neutrophil apoptotic process(GO:0001781) |
| 0.2 | 0.7 | GO:0021502 | neural fold elevation formation(GO:0021502) |
| 0.2 | 12.8 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 0.2 | 1.6 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.2 | 1.0 | GO:0060437 | lung growth(GO:0060437) |
| 0.2 | 2.3 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.2 | 1.1 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.2 | 0.5 | GO:0035038 | female pronucleus assembly(GO:0035038) |
| 0.1 | 0.9 | GO:0002933 | lipid hydroxylation(GO:0002933) |
| 0.1 | 2.9 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 2.3 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.1 | 2.3 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
| 0.1 | 0.8 | GO:0061668 | mitochondrial ribosome assembly(GO:0061668) |
| 0.1 | 2.9 | GO:0060044 | negative regulation of cardiac muscle cell proliferation(GO:0060044) |
| 0.1 | 1.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.1 | 1.1 | GO:0003383 | apical constriction(GO:0003383) |
| 0.1 | 6.4 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.1 | 0.5 | GO:0009236 | cobalamin biosynthetic process(GO:0009236) |
| 0.1 | 2.5 | GO:0070863 | positive regulation of protein exit from endoplasmic reticulum(GO:0070863) |
| 0.1 | 1.0 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.1 | 2.1 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.1 | 0.9 | GO:0022027 | interkinetic nuclear migration(GO:0022027) |
| 0.1 | 0.9 | GO:0003185 | primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) |
| 0.1 | 0.9 | GO:0046098 | guanine metabolic process(GO:0046098) |
| 0.1 | 0.6 | GO:0070980 | biphenyl catabolic process(GO:0070980) |
| 0.1 | 1.2 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.1 | 1.8 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.1 | 1.3 | GO:0035434 | copper ion transmembrane transport(GO:0035434) |
| 0.1 | 0.8 | GO:0070966 | nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) |
| 0.1 | 0.6 | GO:1901727 | positive regulation of histone deacetylase activity(GO:1901727) |
| 0.1 | 0.3 | GO:0006429 | leucyl-tRNA aminoacylation(GO:0006429) |
| 0.1 | 1.6 | GO:0015705 | iodide transport(GO:0015705) |
| 0.1 | 1.2 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189) |
| 0.1 | 0.9 | GO:1901297 | positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068) |
| 0.1 | 0.8 | GO:2000111 | positive regulation of macrophage apoptotic process(GO:2000111) |
| 0.1 | 2.3 | GO:1902373 | negative regulation of mRNA catabolic process(GO:1902373) |
| 0.1 | 0.3 | GO:0072356 | chromosome passenger complex localization to kinetochore(GO:0072356) |
| 0.1 | 12.5 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 2.4 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.1 | 0.3 | GO:0006540 | glutamate decarboxylation to succinate(GO:0006540) |
| 0.1 | 1.1 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 0.1 | 0.4 | GO:0006408 | snRNA export from nucleus(GO:0006408) |
| 0.1 | 1.6 | GO:0008090 | retrograde axonal transport(GO:0008090) |
| 0.1 | 1.4 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.1 | 0.4 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 0.1 | 1.5 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 0.7 | GO:0021943 | regulation of collagen catabolic process(GO:0010710) formation of radial glial scaffolds(GO:0021943) |
| 0.1 | 0.9 | GO:0019255 | glucose 1-phosphate metabolic process(GO:0019255) |
| 0.1 | 1.7 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.1 | 0.6 | GO:0036493 | positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) |
| 0.1 | 0.4 | GO:0097045 | phosphatidylserine exposure on blood platelet(GO:0097045) |
| 0.1 | 1.7 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.1 | 0.2 | GO:0098712 | L-glutamate import across plasma membrane(GO:0098712) |
| 0.1 | 1.4 | GO:0070307 | lens fiber cell development(GO:0070307) |
| 0.1 | 1.1 | GO:0035973 | aggrephagy(GO:0035973) |
| 0.1 | 0.4 | GO:0048341 | paraxial mesoderm formation(GO:0048341) |
| 0.1 | 0.6 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 0.1 | 1.4 | GO:0010818 | T cell chemotaxis(GO:0010818) |
| 0.1 | 3.0 | GO:0060828 | regulation of canonical Wnt signaling pathway(GO:0060828) |
| 0.1 | 1.2 | GO:0034197 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.1 | 0.7 | GO:0030913 | paranodal junction assembly(GO:0030913) |
| 0.1 | 0.4 | GO:0035553 | oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553) |
| 0.1 | 0.8 | GO:0008286 | insulin receptor signaling pathway(GO:0008286) |
| 0.1 | 0.4 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.1 | 0.1 | GO:0060300 | regulation of cytokine activity(GO:0060300) |
| 0.1 | 0.6 | GO:0048194 | Golgi vesicle budding(GO:0048194) |
| 0.1 | 1.6 | GO:0003417 | growth plate cartilage development(GO:0003417) |
| 0.1 | 0.2 | GO:0030505 | inorganic diphosphate transport(GO:0030505) |
| 0.1 | 0.7 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.1 | 0.3 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
| 0.1 | 0.3 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 0.1 | 0.4 | GO:1904796 | regulation of core promoter binding(GO:1904796) |
| 0.1 | 1.3 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.1 | 1.1 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 3.5 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
| 0.1 | 0.9 | GO:0015727 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) |
| 0.1 | 2.7 | GO:0007184 | SMAD protein import into nucleus(GO:0007184) |
| 0.1 | 0.5 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 2.8 | GO:0097435 | fibril organization(GO:0097435) |
| 0.1 | 0.4 | GO:2001013 | epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013) |
| 0.1 | 2.8 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.1 | 0.7 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.1 | 0.3 | GO:0009441 | glycolate metabolic process(GO:0009441) |
| 0.1 | 0.9 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
| 0.1 | 0.7 | GO:0098814 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.1 | 0.5 | GO:0055118 | negative regulation of striated muscle contraction(GO:0045988) negative regulation of cardiac muscle contraction(GO:0055118) |
| 0.1 | 0.4 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.1 | 0.2 | GO:0006579 | amino-acid betaine catabolic process(GO:0006579) |
| 0.1 | 1.5 | GO:0001783 | B cell apoptotic process(GO:0001783) |
| 0.1 | 6.9 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.1 | 0.3 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.1 | 0.5 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.1 | 0.6 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
| 0.1 | 1.5 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.1 | 2.1 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.1 | 0.5 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.0 | 0.5 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.0 | 1.2 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.0 | 0.8 | GO:0051531 | NFAT protein import into nucleus(GO:0051531) |
| 0.0 | 0.3 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
| 0.0 | 0.0 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
| 0.0 | 0.6 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.0 | 0.3 | GO:2000537 | regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 0.0 | 1.2 | GO:0044342 | type B pancreatic cell proliferation(GO:0044342) |
| 0.0 | 0.5 | GO:2000074 | regulation of type B pancreatic cell development(GO:2000074) |
| 0.0 | 0.4 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
| 0.0 | 0.1 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) |
| 0.0 | 1.5 | GO:0042730 | fibrinolysis(GO:0042730) |
| 0.0 | 0.3 | GO:0019236 | response to pheromone(GO:0019236) |
| 0.0 | 0.6 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
| 0.0 | 5.3 | GO:1900181 | negative regulation of protein localization to nucleus(GO:1900181) |
| 0.0 | 0.2 | GO:0061760 | antifungal innate immune response(GO:0061760) |
| 0.0 | 0.8 | GO:0032467 | positive regulation of cytokinesis(GO:0032467) |
| 0.0 | 0.7 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.0 | 0.5 | GO:0006689 | ganglioside catabolic process(GO:0006689) |
| 0.0 | 2.1 | GO:0060706 | cell differentiation involved in embryonic placenta development(GO:0060706) |
| 0.0 | 0.3 | GO:0008343 | adult feeding behavior(GO:0008343) |
| 0.0 | 0.2 | GO:0060005 | vestibular reflex(GO:0060005) |
| 0.0 | 0.3 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.0 | 1.5 | GO:0035666 | TRIF-dependent toll-like receptor signaling pathway(GO:0035666) |
| 0.0 | 0.3 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.0 | 4.6 | GO:0022617 | extracellular matrix disassembly(GO:0022617) |
| 0.0 | 0.1 | GO:1902683 | regulation of receptor localization to synapse(GO:1902683) |
| 0.0 | 1.8 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.0 | 0.1 | GO:0061056 | sclerotome development(GO:0061056) |
| 0.0 | 0.3 | GO:2000767 | positive regulation of cytoplasmic translation(GO:2000767) |
| 0.0 | 8.4 | GO:0006906 | vesicle fusion(GO:0006906) |
| 0.0 | 0.1 | GO:0046373 | arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373) |
| 0.0 | 0.7 | GO:0007635 | chemosensory behavior(GO:0007635) |
| 0.0 | 2.1 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 1.5 | GO:0051646 | mitochondrion localization(GO:0051646) |
| 0.0 | 2.0 | GO:0070423 | nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) |
| 0.0 | 1.2 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.0 | 0.2 | GO:2001034 | positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 0.0 | 0.1 | GO:1903045 | neural crest cell migration involved in sympathetic nervous system development(GO:1903045) |
| 0.0 | 0.6 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.5 | GO:0072189 | ureter development(GO:0072189) |
| 0.0 | 0.2 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.0 | 0.4 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.0 | 0.1 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.0 | 0.2 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
| 0.0 | 1.1 | GO:0050427 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.0 | 0.4 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.2 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.0 | 0.7 | GO:0050832 | defense response to fungus(GO:0050832) |
| 0.0 | 0.2 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.0 | 1.4 | GO:0032784 | regulation of DNA-templated transcription, elongation(GO:0032784) |
| 0.0 | 1.0 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 4.5 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 0.1 | GO:0042214 | terpene metabolic process(GO:0042214) |
| 0.0 | 1.4 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) |
| 0.0 | 6.8 | GO:0016197 | endosomal transport(GO:0016197) |
| 0.0 | 0.1 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.0 | 0.1 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.0 | 0.4 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 0.0 | 0.5 | GO:0036344 | platelet formation(GO:0030220) platelet morphogenesis(GO:0036344) |
| 0.0 | 0.1 | GO:0060693 | regulation of branching involved in salivary gland morphogenesis(GO:0060693) |
| 0.0 | 0.1 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.0 | 0.2 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
| 0.0 | 0.1 | GO:0060029 | convergent extension involved in organogenesis(GO:0060029) |
| 0.0 | 0.3 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
| 0.0 | 0.2 | GO:0090084 | negative regulation of inclusion body assembly(GO:0090084) |
| 0.0 | 1.8 | GO:0030521 | androgen receptor signaling pathway(GO:0030521) |
| 0.0 | 0.6 | GO:0010591 | regulation of lamellipodium assembly(GO:0010591) |
| 0.0 | 0.1 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
| 0.0 | 0.2 | GO:0007039 | protein catabolic process in the vacuole(GO:0007039) |
| 0.0 | 0.5 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 0.0 | 0.3 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.0 | 0.1 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.0 | 0.1 | GO:0090107 | regulation of high-density lipoprotein particle assembly(GO:0090107) |
| 0.0 | 1.5 | GO:0006305 | DNA alkylation(GO:0006305) DNA methylation(GO:0006306) |
| 0.0 | 0.3 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.0 | 0.2 | GO:0006474 | N-terminal protein amino acid acetylation(GO:0006474) |
| 0.0 | 0.1 | GO:0021847 | ventricular zone neuroblast division(GO:0021847) |
| 0.0 | 0.1 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.0 | 0.1 | GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain(GO:0021902) |
| 0.0 | 0.6 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.0 | 0.1 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
| 0.0 | 0.2 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 0.2 | GO:0001502 | cartilage condensation(GO:0001502) |
| 0.0 | 0.5 | GO:0006699 | bile acid biosynthetic process(GO:0006699) |
| 0.0 | 0.5 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.0 | 0.1 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 0.2 | GO:1903392 | negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392) |
| 0.0 | 0.2 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.0 | 0.3 | GO:0033006 | regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 5.0 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.9 | 7.6 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.9 | 2.6 | GO:0005595 | collagen type XII trimer(GO:0005595) |
| 0.7 | 2.9 | GO:0060187 | cell pole(GO:0060187) |
| 0.6 | 9.7 | GO:0030478 | actin cap(GO:0030478) |
| 0.5 | 3.1 | GO:0000308 | cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308) |
| 0.5 | 1.4 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.4 | 21.6 | GO:0005605 | basal lamina(GO:0005605) |
| 0.4 | 1.2 | GO:0019008 | molybdopterin synthase complex(GO:0019008) |
| 0.4 | 1.2 | GO:0008623 | CHRAC(GO:0008623) |
| 0.3 | 1.7 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.3 | 2.0 | GO:0045272 | plasma membrane respiratory chain complex I(GO:0045272) |
| 0.3 | 0.9 | GO:0036457 | keratohyalin granule(GO:0036457) |
| 0.3 | 1.4 | GO:1990425 | ryanodine receptor complex(GO:1990425) |
| 0.3 | 1.6 | GO:0031673 | H zone(GO:0031673) |
| 0.3 | 1.1 | GO:0097635 | extrinsic component of autophagosome membrane(GO:0097635) |
| 0.3 | 1.3 | GO:0031417 | NatC complex(GO:0031417) |
| 0.2 | 0.7 | GO:0034677 | integrin alpha7-beta1 complex(GO:0034677) |
| 0.2 | 0.6 | GO:0000806 | Y chromosome(GO:0000806) |
| 0.2 | 2.5 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.2 | 13.9 | GO:0001533 | cornified envelope(GO:0001533) |
| 0.2 | 2.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.2 | 1.2 | GO:0070369 | Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664) |
| 0.2 | 0.6 | GO:0031592 | centrosomal corona(GO:0031592) |
| 0.1 | 1.0 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
| 0.1 | 0.8 | GO:1990037 | Lewy body core(GO:1990037) |
| 0.1 | 1.8 | GO:0045275 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.1 | 3.5 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 1.4 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.1 | 0.9 | GO:0005587 | collagen type IV trimer(GO:0005587) |
| 0.1 | 0.6 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.1 | 7.9 | GO:0030964 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.1 | 6.7 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 0.9 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 2.5 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 0.6 | GO:0070069 | cytochrome complex(GO:0070069) |
| 0.1 | 0.3 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
| 0.1 | 3.6 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.1 | 3.3 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 0.8 | GO:1990578 | perinuclear endoplasmic reticulum membrane(GO:1990578) |
| 0.1 | 0.7 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
| 0.1 | 0.9 | GO:0002193 | MAML1-RBP-Jkappa- ICN1 complex(GO:0002193) |
| 0.1 | 5.9 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.1 | 1.3 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.1 | 1.4 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.1 | 1.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.1 | 0.7 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.1 | 0.4 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.1 | 5.2 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 2.0 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 1.1 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 6.4 | GO:0005604 | basement membrane(GO:0005604) |
| 0.1 | 0.8 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.1 | 0.8 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 30.0 | GO:0000790 | nuclear chromatin(GO:0000790) |
| 0.0 | 1.4 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.5 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.0 | 7.0 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
| 0.0 | 4.9 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 1.1 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.0 | 5.0 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.0 | 0.9 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 0.0 | 0.5 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 0.0 | 0.3 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.0 | 0.7 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.0 | 5.2 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.4 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.0 | 0.9 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 0.2 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.0 | 0.9 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.0 | 3.4 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.6 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.0 | 0.4 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.0 | 0.3 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 0.3 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.0 | 1.2 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.0 | 0.7 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 0.0 | 0.7 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 1.3 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.0 | 0.6 | GO:0060076 | excitatory synapse(GO:0060076) |
| 0.0 | 0.7 | GO:0005686 | U2 snRNP(GO:0005686) |
| 0.0 | 0.3 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.0 | 9.4 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 3.9 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 0.3 | GO:0061200 | clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202) |
| 0.0 | 0.1 | GO:0031251 | PAN complex(GO:0031251) |
| 0.0 | 2.1 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 0.3 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.0 | 2.5 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.4 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 0.2 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.0 | 3.8 | GO:0043296 | apical junction complex(GO:0043296) |
| 0.0 | 3.0 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 0.2 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 0.3 | GO:0008091 | spectrin(GO:0008091) |
| 0.0 | 0.3 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 2.5 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 1.5 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.0 | 0.6 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.0 | 0.5 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.0 | 0.2 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 0.9 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 0.6 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.0 | GO:0000438 | core TFIIH complex portion of holo TFIIH complex(GO:0000438) |
| 0.0 | 1.2 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.9 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 0.2 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.0 | 0.7 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.0 | 0.5 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 1.7 | GO:0032587 | ruffle membrane(GO:0032587) |
| 0.0 | 0.3 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 2.6 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 0.4 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.0 | 2.0 | GO:0010008 | endosome membrane(GO:0010008) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.7 | 8.0 | GO:0003845 | 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845) |
| 1.0 | 22.1 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 1.0 | 4.8 | GO:0070576 | vitamin D 24-hydroxylase activity(GO:0070576) |
| 0.8 | 4.7 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.5 | 3.5 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 0.4 | 6.7 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.4 | 1.6 | GO:0031728 | CCR3 chemokine receptor binding(GO:0031728) |
| 0.4 | 7.5 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.4 | 7.0 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.4 | 1.4 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 0.4 | 1.1 | GO:0008441 | 3'(2'),5'-bisphosphate nucleotidase activity(GO:0008441) |
| 0.3 | 9.4 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.3 | 2.9 | GO:0043426 | MRF binding(GO:0043426) |
| 0.3 | 0.9 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 0.3 | 1.8 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 0.3 | 4.8 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.3 | 3.0 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.3 | 0.9 | GO:0034875 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 0.3 | 9.5 | GO:0005523 | tropomyosin binding(GO:0005523) |
| 0.3 | 0.8 | GO:0086039 | lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039) |
| 0.3 | 2.1 | GO:0008241 | peptidyl-dipeptidase activity(GO:0008241) |
| 0.3 | 1.3 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 0.2 | 2.6 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.2 | 1.4 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
| 0.2 | 5.5 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.2 | 1.1 | GO:0030375 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.2 | 1.8 | GO:0016679 | oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) |
| 0.2 | 14.0 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.2 | 6.8 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.2 | 1.0 | GO:0016623 | oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) |
| 0.2 | 2.5 | GO:0016909 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.2 | 5.1 | GO:0001608 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.2 | 1.6 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 0.2 | 1.7 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.2 | 2.5 | GO:0089720 | caspase binding(GO:0089720) |
| 0.2 | 2.1 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.2 | 6.9 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.2 | 2.5 | GO:0005221 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.2 | 1.7 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.2 | 6.5 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.2 | 0.8 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 0.1 | 1.0 | GO:0070728 | leucine binding(GO:0070728) |
| 0.1 | 0.7 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 0.1 | 1.5 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.1 | 3.3 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 1.0 | GO:0050816 | phosphothreonine binding(GO:0050816) |
| 0.1 | 0.7 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.1 | 0.4 | GO:0050146 | nucleoside phosphotransferase activity(GO:0050146) |
| 0.1 | 0.9 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 0.1 | 0.9 | GO:0003983 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 0.1 | 1.3 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.1 | 0.5 | GO:0008260 | 3-oxoacid CoA-transferase activity(GO:0008260) |
| 0.1 | 0.3 | GO:0004823 | leucine-tRNA ligase activity(GO:0004823) |
| 0.1 | 3.8 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.1 | 0.3 | GO:0016503 | pheromone receptor activity(GO:0016503) |
| 0.1 | 0.3 | GO:0015432 | bile acid-exporting ATPase activity(GO:0015432) |
| 0.1 | 6.9 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.1 | 1.0 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.1 | 0.5 | GO:0004666 | prostaglandin-endoperoxide synthase activity(GO:0004666) |
| 0.1 | 0.7 | GO:0098639 | collagen binding involved in cell-matrix adhesion(GO:0098639) |
| 0.1 | 0.2 | GO:0070506 | high-density lipoprotein particle receptor activity(GO:0070506) |
| 0.1 | 0.3 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.1 | 3.0 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 5.1 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 0.3 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.1 | 2.2 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.1 | 0.4 | GO:0035515 | oxidative RNA demethylase activity(GO:0035515) |
| 0.1 | 0.8 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
| 0.1 | 1.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 1.3 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 0.1 | 0.5 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.1 | 0.9 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 0.4 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.1 | 3.4 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 2.3 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 1.9 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.1 | 8.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 2.4 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.1 | 2.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.1 | 1.2 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 0.5 | GO:0052794 | exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796) |
| 0.1 | 13.3 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 1.4 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 16.6 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 1.0 | GO:0004791 | thioredoxin-disulfide reductase activity(GO:0004791) |
| 0.1 | 0.3 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.1 | 1.2 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 0.3 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.1 | 2.5 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 0.9 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 0.3 | GO:0072320 | volume-sensitive chloride channel activity(GO:0072320) |
| 0.0 | 5.4 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.0 | 1.6 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.3 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.0 | 0.9 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.0 | 0.3 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.0 | 1.8 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.0 | 0.8 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 1.4 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.0 | 1.6 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.0 | 0.2 | GO:0046997 | oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
| 0.0 | 0.9 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.0 | 2.7 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 2.3 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.0 | 1.1 | GO:0005159 | insulin-like growth factor receptor binding(GO:0005159) |
| 0.0 | 1.1 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.0 | 1.0 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 1.6 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 1.5 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 10.5 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 1.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 1.6 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
| 0.0 | 1.4 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 0.2 | GO:0004977 | melanocortin receptor activity(GO:0004977) |
| 0.0 | 0.3 | GO:0016778 | diphosphotransferase activity(GO:0016778) |
| 0.0 | 0.6 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.1 | GO:0046556 | alpha-L-arabinofuranosidase activity(GO:0046556) |
| 0.0 | 2.9 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 1.4 | GO:0001159 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159) |
| 0.0 | 0.7 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.0 | 2.6 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 1.0 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 1.4 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.0 | 0.7 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 1.6 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 0.5 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.7 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.0 | 0.6 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.0 | 0.2 | GO:0099529 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.0 | 1.0 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.0 | 0.2 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.0 | 0.4 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.0 | 3.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.6 | GO:0017136 | NAD-dependent histone deacetylase activity(GO:0017136) histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) NAD-dependent protein deacetylase activity(GO:0034979) |
| 0.0 | 0.0 | GO:0034618 | arginine binding(GO:0034618) |
| 0.0 | 0.2 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.0 | 0.6 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 15.2 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.0 | 1.1 | GO:0032452 | histone demethylase activity(GO:0032452) |
| 0.0 | 0.9 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 0.1 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.0 | 1.6 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.0 | 0.1 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.0 | 0.9 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.2 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 1.1 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.4 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.0 | 0.4 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.9 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 0.2 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.0 | 0.2 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.0 | 1.4 | GO:0034212 | peptide N-acetyltransferase activity(GO:0034212) |
| 0.0 | 0.3 | GO:0042923 | neuropeptide binding(GO:0042923) |
| 0.0 | 0.8 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.0 | 0.6 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 0.3 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.0 | 0.7 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.3 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.0 | 0.5 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 0.4 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 2.8 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.3 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 0.5 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.0 | 0.1 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.0 | 0.0 | GO:0001515 | opioid peptide activity(GO:0001515) |
| 0.0 | 0.1 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.0 | 0.5 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 1.7 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) |
| 0.0 | 0.2 | GO:0072509 | calcium-transporting ATPase activity(GO:0005388) calcium ion transmembrane transporter activity(GO:0015085) divalent inorganic cation transmembrane transporter activity(GO:0072509) |
| 0.0 | 0.4 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.0 | 0.5 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.2 | GO:0008381 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 0.0 | 0.1 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.0 | 0.5 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 30.4 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.3 | 1.5 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.1 | 26.5 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.1 | 1.7 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.1 | 2.2 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 7.4 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 8.3 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 8.2 | PID FOXO PATHWAY | FoxO family signaling |
| 0.1 | 9.5 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 1.0 | ST PAC1 RECEPTOR PATHWAY | PAC1 Receptor Pathway |
| 0.1 | 7.5 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 21.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 2.1 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.1 | 1.6 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 1.5 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.0 | 2.1 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.8 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 1.5 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.0 | 5.0 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.5 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 5.3 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 1.7 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 3.0 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 13.2 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.0 | 0.3 | ST GAQ PATHWAY | G alpha q Pathway |
| 0.0 | 0.9 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.0 | 2.0 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 2.0 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 4.2 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.7 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 0.9 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.7 | ST GA12 PATHWAY | G alpha 12 Pathway |
| 0.0 | 8.3 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 0.6 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 2.4 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.0 | 0.5 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.4 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 1.2 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.6 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 0.7 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.6 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 0.7 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 0.5 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.0 | 0.6 | PID INTEGRIN2 PATHWAY | Beta2 integrin cell surface interactions |
| 0.0 | 0.5 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.9 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.0 | 1.2 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.0 | 0.2 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.0 | 0.1 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.0 | 0.3 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 5.0 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.4 | 21.9 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.3 | 6.0 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.3 | 5.7 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.2 | 0.9 | REACTOME RECYCLING OF BILE ACIDS AND SALTS | Genes involved in Recycling of bile acids and salts |
| 0.2 | 8.0 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.1 | 2.0 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.1 | 2.5 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 12.5 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 10.0 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 3.5 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 4.3 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.1 | 6.4 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 1.7 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 3.7 | REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.1 | 2.0 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 0.8 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 2.3 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.1 | 2.2 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.1 | 1.3 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 0.7 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.1 | 2.4 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.9 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.0 | 1.5 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 1.1 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.0 | 1.0 | REACTOME ACTIVATED POINT MUTANTS OF FGFR2 | Genes involved in Activated point mutants of FGFR2 |
| 0.0 | 0.9 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.0 | 1.4 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.0 | 0.7 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 1.3 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.0 | 0.9 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.0 | 0.8 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.0 | 2.2 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.0 | 1.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.5 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.0 | 1.9 | REACTOME EXTRACELLULAR MATRIX ORGANIZATION | Genes involved in Extracellular matrix organization |
| 0.0 | 3.4 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.0 | 1.1 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 2.9 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 1.4 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 0.8 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 2.3 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 0.4 | REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS | Genes involved in NRIF signals cell death from the nucleus |
| 0.0 | 0.3 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 1.1 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.4 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.0 | 0.5 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.7 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.0 | 1.0 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.5 | REACTOME PROLACTIN RECEPTOR SIGNALING | Genes involved in Prolactin receptor signaling |
| 0.0 | 0.9 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.5 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.0 | 0.7 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.9 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.0 | 1.6 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 1.7 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.9 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.4 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.3 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.0 | 1.5 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.0 | 1.6 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 1.1 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.0 | 0.6 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.3 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 1.5 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.9 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |