avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Gene Symbol | Gene ID | Gene Info |
---|---|---|
HSF4
|
ENSG00000102878.11 | heat shock transcription factor 4 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
HSF4 | hg19_v2_chr16_+_67198683_67198715 | -0.78 | 5.7e-05 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.7 | 3.7 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
0.7 | 2.8 | GO:0001808 | negative regulation of type IV hypersensitivity(GO:0001808) |
0.5 | 4.1 | GO:1903750 | regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751) |
0.3 | 1.0 | GO:0010160 | sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193) |
0.3 | 0.8 | GO:1901340 | negative regulation of store-operated calcium channel activity(GO:1901340) |
0.3 | 1.0 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
0.3 | 1.8 | GO:0071603 | endothelial cell-cell adhesion(GO:0071603) |
0.2 | 2.2 | GO:0060715 | syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715) |
0.2 | 0.7 | GO:0045041 | B cell cytokine production(GO:0002368) protein import into mitochondrial intermembrane space(GO:0045041) |
0.2 | 1.5 | GO:0070370 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
0.2 | 1.0 | GO:0043335 | protein unfolding(GO:0043335) |
0.2 | 3.5 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
0.2 | 1.4 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
0.2 | 0.7 | GO:2001160 | regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162) |
0.2 | 1.4 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
0.1 | 0.5 | GO:1903660 | negative regulation of complement-dependent cytotoxicity(GO:1903660) |
0.1 | 0.4 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
0.1 | 0.5 | GO:0009956 | radial pattern formation(GO:0009956) |
0.1 | 0.7 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
0.1 | 1.7 | GO:1904871 | regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) |
0.1 | 2.3 | GO:0007191 | adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191) |
0.1 | 1.3 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
0.1 | 0.8 | GO:0035494 | SNARE complex disassembly(GO:0035494) |
0.1 | 0.5 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
0.1 | 0.2 | GO:0043397 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) |
0.1 | 0.7 | GO:0071492 | cellular response to UV-A(GO:0071492) |
0.1 | 0.5 | GO:0015798 | myo-inositol transport(GO:0015798) |
0.1 | 0.3 | GO:1902938 | regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535) |
0.1 | 0.4 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.1 | 0.5 | GO:0019236 | response to pheromone(GO:0019236) |
0.1 | 1.0 | GO:0016926 | protein desumoylation(GO:0016926) |
0.1 | 0.2 | GO:0008355 | olfactory learning(GO:0008355) |
0.1 | 0.2 | GO:0045212 | negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212) |
0.1 | 0.2 | GO:0002424 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) |
0.1 | 0.7 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
0.1 | 0.2 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.0 | 0.5 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.0 | 0.8 | GO:0070970 | interleukin-2 secretion(GO:0070970) |
0.0 | 0.3 | GO:1902231 | regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
0.0 | 0.9 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
0.0 | 0.2 | GO:0071596 | ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596) |
0.0 | 0.5 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.0 | 0.2 | GO:0051066 | dihydrobiopterin metabolic process(GO:0051066) |
0.0 | 0.2 | GO:0072658 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.0 | 1.3 | GO:0032786 | positive regulation of DNA-templated transcription, elongation(GO:0032786) |
0.0 | 0.2 | GO:1905098 | negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
0.0 | 0.1 | GO:0031247 | actin rod assembly(GO:0031247) |
0.0 | 1.1 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.0 | 0.2 | GO:0044856 | plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906) |
0.0 | 0.1 | GO:0036114 | medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535) |
0.0 | 0.6 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
0.0 | 0.6 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
0.0 | 0.2 | GO:0021796 | cerebral cortex regionalization(GO:0021796) |
0.0 | 0.4 | GO:1903599 | positive regulation of mitophagy(GO:1903599) |
0.0 | 0.6 | GO:0007021 | tubulin complex assembly(GO:0007021) |
0.0 | 0.5 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 0.2 | GO:0048254 | snoRNA localization(GO:0048254) |
0.0 | 0.4 | GO:0010917 | negative regulation of mitochondrial membrane potential(GO:0010917) |
0.0 | 0.1 | GO:0003363 | lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816) |
0.0 | 0.3 | GO:0009249 | protein lipoylation(GO:0009249) |
0.0 | 0.4 | GO:0097475 | motor neuron migration(GO:0097475) |
0.0 | 0.3 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
0.0 | 0.4 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
0.0 | 0.7 | GO:0003094 | glomerular filtration(GO:0003094) |
0.0 | 0.4 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.1 | GO:0072738 | response to diamide(GO:0072737) cellular response to diamide(GO:0072738) |
0.0 | 0.5 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
0.0 | 0.8 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.0 | 0.1 | GO:0006424 | glutamyl-tRNA aminoacylation(GO:0006424) |
0.0 | 0.4 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.0 | 0.2 | GO:0006983 | ER overload response(GO:0006983) |
0.0 | 0.5 | GO:0045730 | respiratory burst(GO:0045730) |
0.0 | 0.1 | GO:2000729 | positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729) |
0.0 | 0.2 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
0.0 | 0.9 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 0.4 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
0.0 | 0.1 | GO:0036378 | calcitriol biosynthetic process from calciol(GO:0036378) |
0.0 | 0.3 | GO:0042110 | T cell activation(GO:0042110) leukocyte aggregation(GO:0070486) T cell aggregation(GO:0070489) lymphocyte aggregation(GO:0071593) |
0.0 | 0.1 | GO:0070197 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
0.0 | 0.1 | GO:0042738 | exogenous drug catabolic process(GO:0042738) |
0.0 | 0.3 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 3.7 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
0.4 | 1.8 | GO:0071665 | gamma-catenin-TCF7L2 complex(GO:0071665) |
0.2 | 1.5 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.2 | 5.2 | GO:0071682 | endocytic vesicle lumen(GO:0071682) |
0.1 | 0.7 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
0.1 | 0.4 | GO:0030906 | retromer, cargo-selective complex(GO:0030906) |
0.1 | 0.7 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.1 | 1.7 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
0.1 | 0.4 | GO:1990037 | Lewy body core(GO:1990037) |
0.1 | 0.5 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.1 | 0.5 | GO:0034751 | aryl hydrocarbon receptor complex(GO:0034751) |
0.1 | 0.7 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
0.1 | 0.5 | GO:0032010 | phagolysosome(GO:0032010) |
0.0 | 0.5 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
0.0 | 0.2 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
0.0 | 0.5 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
0.0 | 1.2 | GO:0016580 | Sin3 complex(GO:0016580) |
0.0 | 2.3 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.6 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 0.9 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 0.6 | GO:0097512 | cardiac myofibril(GO:0097512) |
0.0 | 0.4 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.0 | 0.4 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.0 | 0.8 | GO:0042101 | T cell receptor complex(GO:0042101) |
0.0 | 1.5 | GO:0008180 | COP9 signalosome(GO:0008180) |
0.0 | 0.2 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.0 | 0.3 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
0.0 | 0.4 | GO:0044295 | axonal growth cone(GO:0044295) |
0.0 | 0.2 | GO:0043083 | synaptic cleft(GO:0043083) |
0.0 | 0.1 | GO:0044327 | dendritic spine head(GO:0044327) |
0.0 | 0.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
0.0 | 0.2 | GO:0030478 | actin cap(GO:0030478) |
0.0 | 0.8 | GO:0016235 | aggresome(GO:0016235) |
0.0 | 0.3 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.8 | GO:0005199 | structural constituent of cell wall(GO:0005199) |
0.4 | 2.5 | GO:0042015 | interleukin-20 binding(GO:0042015) |
0.3 | 3.7 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
0.3 | 4.1 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
0.2 | 1.3 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
0.2 | 0.5 | GO:0005365 | myo-inositol transmembrane transporter activity(GO:0005365) |
0.1 | 0.6 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
0.1 | 1.0 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
0.1 | 0.7 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
0.1 | 0.7 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
0.1 | 0.4 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
0.1 | 1.0 | GO:0030911 | TPR domain binding(GO:0030911) |
0.1 | 0.5 | GO:0070137 | ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139) |
0.1 | 3.2 | GO:0001671 | ATPase activator activity(GO:0001671) |
0.1 | 0.4 | GO:0070728 | leucine binding(GO:0070728) |
0.1 | 0.5 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
0.1 | 0.3 | GO:1903135 | cupric ion binding(GO:1903135) |
0.1 | 2.3 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
0.1 | 0.2 | GO:0004155 | 6,7-dihydropteridine reductase activity(GO:0004155) |
0.0 | 1.5 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.0 | 0.2 | GO:0003990 | acetylcholinesterase activity(GO:0003990) |
0.0 | 0.9 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
0.0 | 0.4 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
0.0 | 0.7 | GO:0016018 | cyclosporin A binding(GO:0016018) |
0.0 | 1.4 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
0.0 | 0.3 | GO:0019869 | chloride channel inhibitor activity(GO:0019869) |
0.0 | 0.2 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
0.0 | 0.8 | GO:0050700 | CARD domain binding(GO:0050700) |
0.0 | 0.6 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
0.0 | 0.3 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 0.5 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
0.0 | 1.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 2.0 | GO:0015485 | cholesterol binding(GO:0015485) |
0.0 | 0.5 | GO:0001163 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
0.0 | 0.5 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
0.0 | 0.8 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
0.0 | 0.1 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.0 | 0.3 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
0.0 | 3.5 | GO:0031072 | heat shock protein binding(GO:0031072) |
0.0 | 0.4 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.0 | 0.1 | GO:0004818 | glutamate-tRNA ligase activity(GO:0004818) |
0.0 | 0.7 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
0.0 | 0.4 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
0.0 | 0.1 | GO:0036042 | long-chain fatty acyl-CoA binding(GO:0036042) |
0.0 | 0.1 | GO:0030343 | vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643) |
0.0 | 0.8 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
0.0 | 0.2 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
0.0 | 0.6 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
0.0 | 0.5 | GO:0031491 | nucleosome binding(GO:0031491) |
0.0 | 0.1 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
0.0 | 1.1 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
0.0 | 0.6 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
0.0 | 0.1 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 0.1 | GO:0046790 | virion binding(GO:0046790) |
0.0 | 0.8 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 1.0 | GO:0004177 | aminopeptidase activity(GO:0004177) |
0.0 | 0.8 | GO:0031593 | polyubiquitin binding(GO:0031593) |
0.0 | 0.7 | GO:0051082 | unfolded protein binding(GO:0051082) |
0.0 | 0.2 | GO:0045159 | myosin II binding(GO:0045159) |
0.0 | 1.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.9 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
0.0 | 1.0 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
0.0 | 1.8 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
0.0 | 4.2 | PID CMYB PATHWAY | C-MYB transcription factor network |
0.0 | 0.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
0.0 | 1.4 | PID PLK1 PATHWAY | PLK1 signaling events |
0.0 | 1.5 | PID LKB1 PATHWAY | LKB1 signaling events |
0.0 | 0.2 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.9 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.1 | 3.7 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
0.1 | 2.3 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
0.0 | 1.0 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
0.0 | 1.8 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
0.0 | 1.1 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
0.0 | 0.5 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
0.0 | 1.4 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
0.0 | 0.5 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
0.0 | 0.3 | REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR | Genes involved in Prostacyclin signalling through prostacyclin receptor |
0.0 | 0.9 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
0.0 | 0.4 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
0.0 | 0.5 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
0.0 | 0.8 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
0.0 | 1.2 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
0.0 | 0.2 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
0.0 | 1.8 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
0.0 | 0.7 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |