ISMARA results: HSFY2

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avrg: SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HSFY2

Z-value: 1.94

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Transcription factors associated with HSFY2

Gene Symbol	Gene ID	Gene Info
HSFY2 Ensembl NCBI GeneCards UniProt	ENSG00000169953.11	heat shock transcription factor Y-linked 2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
HSFY2	hg19_v2_chrY_-_20935572_20935621	-0.63	3.1e-03	Click!

Activity profile of HSFY2 motif

Sorted Z-values of HSFY2 motif

No targets for HSFY2

Network of associatons between targets according to the STRING database.

First level regulatory network of HSFY2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	7.1	GO:0042908	xenobiotic transport(GO:0042908)
0.1	6.0	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.2	5.5	GO:0051382	kinetochore assembly(GO:0051382)
0.0	5.1	GO:0007052	mitotic spindle organization(GO:0007052)
0.6	4.9	GO:0009753	response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.9	4.6	GO:0036343	psychomotor behavior(GO:0036343)
0.9	4.5	GO:1903613	regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.1	4.4	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.4	4.2	GO:2000371	regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
1.0	4.1	GO:1990926	short-term synaptic potentiation(GO:1990926)

Showing 1 to 10 of 236 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	7.6	GO:0043235	receptor complex(GO:0043235)
0.0	5.7	GO:0000776	kinetochore(GO:0000776)
0.1	5.0	GO:0031143	pseudopodium(GO:0031143)
0.0	4.3	GO:0005758	mitochondrial intermembrane space(GO:0005758)
0.5	4.1	GO:0070032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2	4.0	GO:0001741	XY body(GO:0001741)
0.6	3.9	GO:0031262	Ndc80 complex(GO:0031262)
0.1	3.8	GO:1902711	GABA-A receptor complex(GO:1902711)
0.1	3.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	2.9	GO:0032421	stereocilium bundle(GO:0032421)

Showing 1 to 10 of 106 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	7.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.1	6.0	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.3	5.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.7	4.9	GO:0018636	phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1	4.9	GO:0005484	SNAP receptor activity(GO:0005484)
0.0	4.3	GO:0004386	helicase activity(GO:0004386)
0.4	4.2	GO:0043515	kinetochore binding(GO:0043515)
0.1	4.2	GO:0050811	GABA receptor binding(GO:0050811)
0.2	4.0	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.5	3.7	GO:0015057	thrombin receptor activity(GO:0015057)

Showing 1 to 10 of 159 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	10.5	PID AURORA B PATHWAY	Aurora B signaling
0.1	7.3	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.1	5.7	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	3.5	PID AURORA A PATHWAY	Aurora A signaling
0.1	3.4	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	2.1	PID ATR PATHWAY	ATR signaling pathway
0.0	2.0	PID MTOR 4PATHWAY	mTOR signaling pathway
0.0	1.9	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	1.6	PID CMYB PATHWAY	C-MYB transcription factor network
0.0	1.4	PID RHOA PATHWAY	RhoA signaling pathway

Showing 1 to 10 of 22 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	11.5	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.1	9.3	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	6.7	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
0.3	6.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	6.1	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.1	5.0	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.2	4.1	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1	4.1	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.1	3.8	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	2.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane

Showing 1 to 10 of 61 entries

Results for HSFY2

Z-value: 1.94

Motif logo

Transcription factors associated with HSFY2

Activity-expression correlation:

Activity profile of HSFY2 motif

Sorted Z-values of HSFY2 motif

No targets for HSFY2

Network of associatons between targets according to the STRING database.

First level regulatory network of HSFY2

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: